Anestesia regional

  • 文章类型: Journal Article
    OBJECTIVE: The aim of this study is to evaluate the effect of erector spinae plane block (ESPB) as a rescue therapy in the recovery room.
    METHODS: This single-center historical cohort study included patients who received either ESPB or intravenous meperidine for pain management in the recovery room. Patients\' numeric rating scale (NRS) scores and opoid consumptions were evaluated.
    RESULTS: One hundred and eight patients were included in the statistical analysis. Sixty-two (57%) patients received ESPB postoperatively (pESPB) and 46 (43%) patients were managed with IV meperidine boluses only (IV). The cumulative meperidine doses administered were 0 (0-40) and 30 (10-80) mg for the pESPB and IV groups, respectively (p < 0.001). NRS scores of group pESPB were significantly lower than those of Group IV on T30 and T60.
    CONCLUSIONS: ESPB reduces the frequency of opioid administration and the amount of opioids administered in the early post-operative period. When post-operative rescue therapy is required, it should be considered before opioids.
    OBJECTIVE: Evaluar el efecto del bloqueo del plano erector espinal (ESPB) como terapia de rescate en la sala de recuperación.
    UNASSIGNED: Este estudio de cohortes histórico de un solo centro incluyó a pacientes que recibieron ESPB o meperidina intravenosa para el tratamiento del dolor en la sala de recuperación. Se evaluaron las puntuaciones de la escala de calificación numérica (NRS) de los pacientes y los consumos de opiáceos.
    RESULTS: En el análisis estadístico se incluyeron 108 pacientes. Recibieron ESPB 62 (57%) pacientes y los otros 46 (43%) fueron manejados solo con bolos de meperidina intravenosa. Las dosis acumuladas de meperidina administradas fueron 0 (0-40) y 30 (10-80) mg para los grupos de ESPB y de meperidina sola, respectivamente (p < 0.001). Las puntuaciones de dolor del grupo ESPB fueron significativamente más bajas que las del grupo de meperidina sola en T30 y T60.
    CONCLUSIONS: El ESPB reduce la frecuencia de administración de opiáceos y la cantidad de estos administrada en el posoperatorio temprano. Cuando se requiera terapia de rescate posoperatoria, se debe considerar antes que los opiáceos.
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  • 文章类型: Journal Article
    医学在大多数领域的不断发展要求医生应用最新的方法和技术来确保患者的安全。在麻醉学领域,我们是确保患者安全的措施应用的先驱,使死亡率在所有其他专业中的最大降低成为可能。由于引入了诸如本评论文章中介绍的更改,因此实现了这一目标。神经轴和其他区域麻醉应用的特定NRFit®连接可防止发生错误路径的用药错误。这些药物错误与高发病率和死亡率有关。本文根据我们在阿斯图里亚斯大学医院的两年经验回顾了这项新技术(AlcaládeHenares,马德里)以及使用PubMed的文献综述,UpToDate和ClinicalKey。
    The continuous development of medicine in most fields requires physicians to apply the latest methods and technology to ensure patients\' safety. In the field of anesthesiology we are pioneers in the application of measures that guarantee the security of our patients, making possible the greatest reduction in mortality seen among all other specialties. This objective has been achieved thanks to the introduction of changes such as the one presented in this review article. The specific NRFit® connections for neuraxial and other regional anesthesia applications prevent wrong route medication errors to occur. These medication errors have been related to a high morbidity and mortality rate. This article reviews this new technology based in our own two-year experience at Hospital Universitario Príncipe de Asturias (Alcalá de Henares, Madrid) as well as a literature review using PubMed, UpToDate and ClinicalKey.
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  • 文章类型: Journal Article
    背景:先前的研究表明,超声引导的锁骨阻滞可能需要两次注射才能提供足够的,快速感觉和运动阻滞。在这次审判中,我们假设在进行单次锁骨阻滞时,如果使用角袋入路(在腋窝动脉和正中脊髓之间)而不是中央入路(在3根脊髓的中点),封锁的开始将不劣于双射技术。
    方法:在三级医院接受上肢手术的90例患者随机分为2组,分别接受超声引导下前锁骨阻滞(CCB)。一组使用角袋方法接受超声引导的单发CCB,另一组接受超声引导的双发-第一发在3根绳索的中心,第二发在腋下动脉和正中绳索之间。对小组分配视而不见的观察者记录了阻滞开始时间(定义为达到16分中的14分的最小感觉运动综合评分所需的时间)。
    结果:在评估合格的101名患者中,在1年期间(2022年2月至2023年1月)招募了90人,每组45人。单发组发病时间为22.1±3.1min,双发组发病时间为22.4±2.9min。这种差异是不显著的(p=0.3)。
    结论:在单次注射角袋CCB和两次注射CCB中,阻滞和完全麻醉的开始时间相似。需要进一步的研究来确定所述技术所需的局部麻醉剂的最小有效体积。
    BACKGROUND: Previous studies have shown that ultrasound guided costoclavicular block may require a double shot to provide adequate, rapid sensory and motor blockade. In this trial, we hypothesized that if the corner pocket approach (between axillary artery and median cord) is used instead of the central approach (at the midpoint of the 3 cords) when performing single-shot costoclavicular block, the onset of blockade would be non-inferior to the double-shot technique.
    METHODS: Ninety patients undergoing upper limb surgery were randomized to 2 groups for ultrasound-guided costoclavicular block (CCB) at a tertiary hospital. One group received ultrasound guided single-shot CCB using the corner pocket approach and other received ultrasound guided double-shot - the first shot at the centre of the 3 cords and the second between the axillary artery and the median cord. An observer blinded to group assignment recorded blockade onset time (defined as the time required to achieve a minimal sensorimotor composite score of 14 out of 16 points).
    RESULTS: Of the 101 patients assessed for eligibility, 90 were recruited over period of 1 year (February 2022 to January 2023), with 45 in each group. Onset time was 22.1 ± 3.1 min in the single-shot group and 22.4 ± 2.9 min in the double-shot group. This difference was insignificant (P = .3).
    CONCLUSIONS: Time to onset of blockade and full anaesthesia are similar in single-shot corner pocket CCB vs double-shot CCB. Further studies are required to determine the minimum effective volume of local anaesthetic required for the described technique.
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  • 文章类型: Case Reports
    PENG阻滞(包膜神经组)是最近描述的解决髋关节神经支配的技术,在局部区域水平治疗的最复杂的解剖区域之一。我们介绍了一例急性淋巴细胞白血病并发双侧股骨头缺血性坏死,先前有严重的慢性疼痛病史,可能对阿片类药物有中枢敏感性,并由于化疗引起的骨髓毒性而导致严重的血小板减少症。鉴于需要骨科手术来处理股骨头坏死,并且预期复杂的围手术期疼痛管理,我们计划采用多模式策略,包括双侧超声引导下连续PENG阻滞,以在围手术期实现适当的疼痛控制并促进早期恢复.手术和最初恢复顺利,患者在24小时内出院并按计划开始早期康复。患者恢复成功,功能良好。
    The PENG block (pericapsular nerve group) is a recently described technique to address the innervation of the hip, one of the most complex anatomical regions to treat at the locoregional level. We present the case of a patient with acute lymphoblastic leukaemia complicated by avascular necrosis of the bilateral femoral head and previous history of severe chronic pain with probable central sensitization to opioids and a severe thrombocytopenia due to myelotoxicity from chemotherapy treatment. Given the need for orthopaedic surgery to manage femoral necrosis and in anticipation of complex perioperative pain management, a multimodal strategy was planned including bilateral ultrasound-guided continuous PENG blocks to achieve proper pain control in the perioperative period and promote early recovery. The operation and initial recovery were uneventful and the patient was discharged to the ward within 24 h and started early rehabilitation as planned. The patient had a successful recovery with good functionality.
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  • 文章类型: Journal Article
    背景:全髋关节置换术是医院环境中最常见的外科干预措施之一。尽管如此,治疗术后疼痛的理想方法仍然未知.基于区域麻醉的多模式镇痛技术是最有前途的解决方案之一。
    目的:本研究的目的是根据是否进行周围神经阻滞(股骨阻滞,髂筋膜阻滞和囊周神经组阻滞)。测量患者在麻醉后监护病房期间的静脉吗啡消耗量,以及干预后24小时和48小时的阿片类药物抢救次数。作为次要目标,神经损伤的患病率,延长四头肌阻滞,和吗啡消费量是根据其他感兴趣的变量确定的。
    方法:在这项观察性回顾性研究中,数据来自2018年4月至2020年8月656名创伤手术患者的电子病历,纳入标准如下:18岁以上,ASAI-III,在全身麻醉或蛛网膜下腔麻醉下进行初次全髋关节置换术(仅使用高压布比卡因),并使用左布比卡因进行周围神经阻滞。
    结果:共选择362例患者。手术指征主要为髋关节病(61.3%),其次是髋部骨折(22.6%)。对169例患者进行了周围神经阻滞(66.3%,27.7%PENG,和6.0%的髂筋膜)。在接受PENG(2.2mg)或股骨(3.27mg)阻滞的患者中,PACU的平均术后阿片类药物消耗量较低,与未接受治疗的患者相比(6.69mg)。手术后24小时和48小时的阿片类药物抢救没有差异。神经损伤发生率较低(.8%),与神经阻滞无关.长期四头肌麻痹的发生率也很低(1.3%),并且主要与股神经阻滞有关(占病例的75%)。
    结论:这项回顾性研究支持使用区域块作为遮光剂保护技术,强调它们在无运动损害的快速功能恢复中的作用。
    BACKGROUND: Total hip arthroplasty is one of the most frequent surgical interventions in the hospital setting. Nonetheless, the ideal method to manage post-operative pain is still unknown. Multimodal analgesia techniques based on regional anaesthesia are amongst the most promising solutions.
    OBJECTIVE: The aim of this study was to evaluate postoperative pain after total hip arthroplasty according to whether peripheral nerve block was performed (femoral block, fascia iliaca block and pericapsular nerve group block). Intravenous morphine consumption during the patient\'s stay in the post-anaesthesia care unit was measured, as well as the number of opioid rescues at 24 and 48 h post intervention. As secondary objectives, the prevalence of nerve injury, prolonged quadricipital block, and morphine consumption were established according to other variables of interest.
    METHODS: In this observational retrospective study, data was collected from the electronic medical record of 656 traumatological surgery patients from April 2018 to August 2020, with the following inclusion criteria: over 18 years old, ASA I-III, primary total hip arthroplasty under general anaesthesia or subarachnoid anaesthesia (only with hyperbaric bupivacaine) and use of levobupivacaine for peripheral nerve block.
    RESULTS: A total of 362 patients were selected. The main surgical indication was coxarthrosis (61.3%), followed by hip fracture (22.6%). Peripheral nerve blocks were performed on 169 patients (66.3% femoral, 27.7% PENG, and 6.0% fascia iliaca). Mean postoperative opioid consumption in PACU was lower in patients in who received a PENG (2.2 mg) or a femoral (3.27 mg) block, compared to those who received neither (6.69 mg). There were no differences in opioid rescues at 24 and 48 h after the procedure. Nerve injury incidence was low (.8%), and not associated with nerve blocks. The incidence of prolonged quadricipital paralysis was also low (1.3%), and was mainly associated with femoral nerve block (75% of cases).
    CONCLUSIONS: This retrospective study supports the use of regional blocks as opioid-sparing techniques, highlighting their role in rapid functional recovery with no motor impairment.
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    文章类型: English Abstract
    UNASSIGNED: Comprehensive health care includes the evaluation of satisfaction in patient care and the quality of medical services. High-precision instruments have been used to assess the quality of recovery after anesthesia (QoR), such as the QoR-15 questionnaire, a validated and accurate assessment tool that considers aspects of emotionality, physical and psychological well-being, pain, and autonomy.
    UNASSIGNED: To assess QoR in postoperative patients who underwent anesthesia.
    UNASSIGNED: Observational, descriptive, cross-sectional study, carried out from March to August 2022. 80 patients from 18 to 70 years who underwent an anesthetic procedure and to which the anesthetic quality QoR-15 questionnaire was administered 24 hours after surgery were included. Descriptive statistics were performed according to the Shapiro-Wilk test. For quantitative variables it was used Mann-Whitney U, and for qualitative variables chi-squared; it was considered significant a value of p < 0.05.
    UNASSIGNED: The 80 patients obtained a QoR-15 score of 122.06 (52-147), and their QoR was considered good. Anesthetic recovery quality in patients undergoing regional anesthetic techniques was excellent in 42.5% and 10% had balanced general anesthesia, p = 0.011.
    UNASSIGNED: QoR was higher with regional anesthetic techniques. Quality assessment through validated tools allows objective evaluation and monitoring of the care process in medical services.
    UNASSIGNED: la atención sanitaria integral incluye la satisfacción en la atención del paciente y la calidad de servicios médicos. Se han empleado instrumentos con alta precisión para evaluar la calidad de recuperación anestésica (CRA), como el cuestionario validado QoR-15, el cual considera aspectos sobre emocionalidad, bienestar físico y psicológico, dolor y autonomía física.
    UNASSIGNED: evaluar la CRA en pacientes postoperados sometidos a anestesia.
    UNASSIGNED: estudio observacional, descriptivo, transversal, realizado de marzo a agosto de 2022. Se incluyeron 80 pacientes de 18 a 70 años sometidos a procedimiento anestésico y a quienes se les aplicó el cuestionario de calidad anestésica QoR-15 a las 24 horas de postoperados. Se empleó estadística descriptiva de acuerdo con la prueba de Shapiro-Wilk. Las variables cuantitativas se analizaron con U de Mann-Whitney y las cualitativas con chi cuadrada; se consideró significativo un valor de p < 0.05.
    UNASSIGNED: los 80 pacientes obtuvieron 122.06 (52-147) puntos en el cuestionario QoR-15 y su CRA se consideró como buena; en los pacientes sometidos a técnicas anestésicas regionales la CRA fue excelente en 42.5% y 10% tuvieron anestesia general balanceada, p = 0.011.
    UNASSIGNED: la CRA fue mayor con las técnicas anestésicas regionales. La evaluación de la calidad mediante herramientas validadas permite su evaluación objetiva y hacer seguimiento del proceso de atención en los servicios médicos.
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  • 文章类型: Journal Article
    目的:颈动脉内膜切除术中颈动脉交叉钳夹可能导致术中神经功能缺损,增加中风/死亡风险。如果发现缺陷,颈动脉分流术已被推荐用于降低中风的风险。然而,分流可能会维持栓塞事件的特定机会并随后造成伤害。关于其明显的益处,目前的证据仍然值得怀疑。目的是确定选择性分流政策是否会影响动脉内膜切除术后的并发症发生率。
    方法:从2013年1月至2021年5月,在区域麻醉下进行颈动脉内膜切除术的所有患者进行术中神经系统改变。将接受选择性分流的患者与非分流组进行比较。进行1:1倾向评分匹配(PSM)。计算组间差异和临床结果,诉诸单变量分析。
    结果:选择98例患者,其中23人使用分流术进行手术。PSM之后,将22名非分流患者与22名匹配的分流患者进行比较。关于人口统计学和合并症,两组均与PSM前和后相当,除了慢性心力衰竭,在分流患者中更为普遍(26.1%,在PSM前分析中P=0.036)。关于30天的卒中和Clavien-Dindo评分≥2,没有发现显着关联(P=0.730,P=0.635和P=0.942,P=0.472,相应地,对于PSM之前和之后)。
    结论:在这个队列中,对于30天的卒中或Clavien-Dindo≥2的发生率,采用分流术未显示出优势。然而,需要更多更广泛的研究来获得关于颈动脉分流在区域麻醉下的这一部分患者中的准确效用的准确结果.
    Carotid cross-clamping during carotid endarterectomy might lead to intraoperative neurologic deficits, increasing stroke/death risk. If deficits are detected, carotid shunting has been recommended to reduce the risk of stroke. However, shunting may sustain a specific chance of embolic events and subsequently incurring harm. Current evidence is still questionable regarding its clear benefit. The aim is to determine whether a policy of selective shunt impacts the complication rate following an endarterectomy.
    From January 2013 to May 2021, all patients undergoing carotid endarterectomy under regional anesthesia with intraoperative neurologic alteration were retrieved. Patients submitted to selective shunt were compared to a non-shunt group. A 1:1 propensity score matching (PSM) was performed. Differences between the groups and clinical outcomes were calculated, resorting to univariate analysis.
    Ninety-eight patients were selected, from which 23 were operated on using a shunt. After PSM, 22 non-shunt patients were compared to 22 matched shunted patients. Concerning demographics and comorbidities, both groups were comparable to pre and post-PSM, except for chronic heart failure, which was more prevalent in shunted patients (26.1%, P=0.036) in pre-PSM analysis. Regarding 30-day stroke and score Clavien-Dindo ≥2, no significant association was found (P=0.730, P=0.635 and P=0.942, P=0.472, correspondingly, for pre and post-PSM).
    In this cohort, resorting to shunting did not demonstrate an advantage regarding 30-day stroke or a Clavien-Dindo ≥ 2 rates. Nevertheless, additional more extensive studies are mandatory to achieve precise results concerning the accurate utility of carotid shunting in this subset of patients under regional anesthesia.
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  • 文章类型: Case Reports
    我们报告了一例儿科患者,该患者在急诊科就诊,因蝎子刺痛而导致右下肢严重疼痛。镇痛药无效,所以我们决定做一个超声引导下的关节阻滞.这个,实现了完全镇痛,并允许患者在门诊接受随访,没有不良影响。在西班牙发现的蝎子种类的刺痛对人类生命并不危险;但是,它会导致持续24-48小时的自限性局部疼痛,可能很严重。一线治疗是有效的镇痛。区域麻醉技术可用于控制急性疼痛,是麻醉学和紧急服务之间有效合作的一个例子。
    We report the case of a paediatric patient who presented at the Emergency Department with severe pain in the right lower extremity caused by a scorpion sting. Analgesics were ineffective, so we decided to perform an ultrasound-guided popliteal block, which provided complete analgesia and allowed the patient to be followed up in the outpatient department, with no adverse effects. The sting of the species of scorpion found in Spain is not dangerous to human life; however, it causes self-limiting localised pain that lasts for 24-48h, and can be severe. The first-line treatment is effective analgesia. Regional anaesthesia techniques are useful in the control of acute pain, and are an example of effective collaboration between the Anaesthesiology and Emergency services.
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  • 文章类型: Case Reports
    传统上,乳房切除术是在全身麻醉和有创通气下进行的,并经常辅以区域性技术。在此设置中,气管狭窄可能对气道管理构成挑战。本报告的目的是描述一名68岁的女性,该女性患有严重的声门下气管狭窄,因乳腺癌而接受乳房切除术。在无阿片类药物的方案下,在没有气道器械的情况下进行手术,丙泊酚和右美托咪定灌注,和非阿片类镇痛药。实现了自发通气和充分的围手术期镇痛。无阿片类药物无气道器械麻醉,包括胸段硬膜外麻醉和镇静,对于接受乳房切除术的患者是一个很好的选择,在这些患者中,最好避免气道操作。
    The report of anesthetic technique failure is crucial and the etiology of the problem should be determined. We describe a case of locoregional anesthesia failure, in which, after excluding its most common causes, the resistance to local anesthetics was considered as the most probable clinical hypothesis. For this reason, a genetic test was performed, as well as the efficacy of other local anesthetics was evaluated, constituting a different approach in the cases of locoregional anesthesia failure. True resistance to local anesthetics is difficult to diagnose so information about this is scarce in the literature. One of the proposed causes is a mutation of sodium channels where local anesthetics bind. If not recognized, the application of locorregional anesthesia in this patient\'s condition can lead to unpleasant experiences and unnecessary risks, related to toxic levels of local anesthetics. For this reason, the resistance to local anesthetics should be always precluded in cases of strong clinical suspicion. This approach could be applied in similar cases.
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  • 文章类型: Systematic Review
    药物和给药途径的结合产生了协同作用,多模式镇痛策略的最重要组成部分之一是,因此,用于疼痛管理的神经阻滞。局部麻醉剂的作用可以通过施用佐剂来延长。在这次系统审查中,我们纳入了最近5年发表的关于周围神经阻滞中与局部麻醉药相关的佐剂的研究,以评估其有效性.根据PRISMA指南报告结果。使用我们的标准选择的79项研究显示,地塞米松(n=24)和右美托咪定(n=33)明显高于其他佐剂。比较佐剂的不同荟萃分析表明,与右美托咪定相比,经神经外给药的地塞米松可实现更好的阻滞,副作用更少。根据审查的研究,我们发现中度证据推荐在可引起中度至重度疼痛的手术中使用地塞米松作为外周区域麻醉的辅助药物.
    The combination of drugs and routes of administration produces a synergistic effect, and one of the most important components of multimodal analgesic strategies are, therefore, nerve blocks for pain management. The effect of a local anaesthetic can be prolonged by administering an adjuvant. In this systematic review, we included studies on adjuvants associated with local anaesthetics in peripheral nerve blocks published in the last 5 years in order to evaluate their effectiveness. The results were reported according to the PRISMA guidelines. The 79 studies selected using our criteria showed a clear prevalence of dexamethasone (n=24) and dexmedetomidine (n=33) over other adjuvants. Different meta-analyses comparing adjuvants suggest that dexamethasone administered perineurally achieves superior blockade with fewer side effects than dexmedetomidine. Based on the studies reviewed, we found moderate evidence to recommend the use of dexamethasone as an adjuvant to peripheral regional anaesthesia in surgeries that can cause moderate to severe pain.
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