斑疹伤寒,流行的热带感染,有时可能表现为不寻常的并发症。这里,我们介绍了一个年轻人的案例,他在过去的三天里发烧,并从那天早上开始出现深色尿液。在调查中,我们发现了血管内溶血性贫血.通过细致的检查,在他的右臀部发现了一个黑色坏死病变(焦痂),斑疹伤寒感染的病理标志。用口服多西环素100mg开始治疗,每天两次。随后,通过ELISA和焦痂组织的PCR分析,斑疹伤寒IgM阳性结果证实了斑疹伤寒的诊断。患者对口服多西环素反应良好,在接下来的几天内症状缓解。此病例突出了与斑疹伤寒感染相关的严重血管内溶血。
Scrub typhus, a prevalent tropical infection, may sometimes manifest with unusual complications. Here, we present the case of a young man who was admitted to our facility with a fever for the past 3 days and passage of dark-coloured urine since that morning. On investigation, we identified intravascular haemolytic anaemia. Through meticulous examination, a black necrotic lesion (eschar) was discovered on his right buttock, a pathognomonic sign of scrub typhus infection. Treatment was initiated with oral doxycycline 100 mg two times a day. Subsequently, diagnosis of scrub typhus was confirmed through positive results from scrub typhus IgM via ELISA and PCR analysis from the eschar tissue. The patient responded well to oral doxycycline and his symptoms resolved within the next few days. This case highlights severe intravascular haemolysis associated with scrub typhus infection.