目的:神经血管内手术依赖于成功的导航和目标血管的稳定通路。稳定器是一根300厘米长的交换线,直径为0.014,远端柔性支架设计用于辅助导航和装置输送。本研究旨在评估稳定器在各种具有挑战性的环境中的导航功效。
方法:使用三种具有挑战性的血管模型评估稳定剂的功效:巨大的动脉瘤模型,严重的弯曲模型,和M1狭窄模型。在每个模型的导航过程中,将稳定器与常规导线进行了比较。
结果:在巨大动脉瘤模型中,与传统导丝相比,将带稳定器的中间导管推进超过动脉瘤颈部时,在拉直环线期间的成功率没有显著差异,且成功率明显更高.与传统导丝相比,当推进中间导管通过严重弯曲的模型时,稳定器还显著提高了成功率。以及与交换线相比,狭窄模型中颅内支架置入的交换操作。
结论:在我们的实验模型中,与传统的电线相比,稳定器在各种具有挑战性的环境下显着改善了导航和设备交付。
OBJECTIVE: Neuroendovascular procedures rely on successful navigation and stable access to the target vessel. The Stabilizer is a 300 cm long exchange wire with a 0.014 diameter and a soft, flexible stent at the distal end designed to assist with navigation and device delivery. This study aims to assess the efficacy of the Stabilizer for navigation in a variety of challenging environments.
METHODS: The efficacy of the Stabilizer was evaluated using three challenging vascular models: a giant aneurysm model, a severe tortuosity model, and an M1 stenosis model. The Stabilizer was compared with a conventional wire during navigation in each model.
RESULTS: In the giant aneurysm model, there was no significant difference of success during straightening of a looped wire and significantly higher success rates when advancing an intermediate catheter with the Stabilizer beyond the aneurysm neck compared to a conventional guidewire. The Stabilizer also significantly increased success rates when advancing an intermediate catheter through a model with severe tortuosity compared to a conventional guidewire, as well as exchange maneuver for intracranial stenting in a stenosis model compared to an exchange wire.
CONCLUSIONS: In our experimental model, the Stabilizer significantly improved navigation and device delivery in a variety of challenging settings compared to conventional wires.