目的:最常见的异常是起源于肺动脉的左冠状动脉异常。这些变体可以是不同的,并且取决于位置以及它们如何在它们的解剖分布和它们的症状关系中呈现它们自己。由于这些原因,这篇综述旨在确定冠状动脉的变异以及它们如何与不同的临床状况相关联。
方法:数据库Medline,Scopus,WebofScience,谷歌学者,CINAHL,和LILACS的研究一直持续到2024年1月。两位作者独立进行了搜索,研究选择,和数据提取。使用解剖学研究的保证工具(AQUA)评估方法学质量。使用随机效应模型估计合并患病率。
结果:共有39项研究符合既定的选择标准。在这项研究中,21篇文章共578,868名受试者纳入荟萃分析。冠状动脉起源变异为1%(CI=0.8-1.2%)。对于第三个样本,漏斗图显示了一个重要的不对称性,p值为0.162,这与这种不对称性直接相关。
结论:建议诊断为偶然且没有症状的患者进行定期控制,以防止将来出现并发症,包括死亡。最后,我们相信进一步的研究可以改善解剖学,胚胎学,以及对心脏这种变异的生理理解。
OBJECTIVE: The most common anomaly is an anomalous left coronary artery originating from the pulmonary artery. These variants can be different and depend on the location as well as how they present themselves in their anatomical distribution and their symptomatological relationship. For these reasons, this review aims to identify the variants of the coronary artery and how they are associated with different clinical conditions.
METHODS: The databases Medline, Scopus, Web of Science, Google Scholar, CINAHL, and LILACS were researched until January 2024. Two authors independently performed the search, study selection, and data extraction. Methodological quality was evaluated using an assurance tool for anatomical studies (AQUA). Pooled prevalence was estimated using a random effects model.
RESULTS: A total of 39 studies met the established selection criteria. In this study, 21 articles with a total of 578,868 subjects were included in the meta-analysis. The coronary artery origin variant was 1% (CI = 0.8-1.2%). For this third sample, the funnel plot graph showed an important asymmetry, with a p-value of 0.162, which is directly associated with this asymmetry.
CONCLUSIONS: It is recommended that patients whose diagnosis was made incidentally and in the absence of symptoms undergo periodic controls to prevent future complications, including death. Finally, we believe that further studies could improve the anatomical, embryological, and physiological understanding of this variant in the heart.