Anaesthetics

麻醉药
  • 文章类型: Journal Article
    人工智能(AI)在麻醉中的潜在应用是广泛的。~然而,像任何技术进步一样,人工智能在麻醉实践中的整合既有好处,也有潜在的风险。本文旨在阐明在麻醉领域使用AI技术的一些优点和缺点。在麻醉中应用AI的好处包括改善围手术期风险分层,麻醉计划的个性化,提高效率,最终降低医疗成本。然而,对技术的依赖可能会降低临床敏锐度,但此外,还有围绕数据质量的问题,隐私以及法律和道德问题,这需要进一步评估。虽然麻醉实践中的AI拥有巨大的前景,有大量的挑战需要仔细考虑和持续评估。需要医护人员采取协作方式,开发商和监管机构推广保险箱,负责任,人工智能在麻醉实践中的有效应用。
    The potential applications of Artificial Intelligence (AI) in anaesthesia are expansive.~However, like any technological advancement, the integration of AI in anaesthetic practice comes with both benefits and potential risks. This article seeks to set out some of the advantages and disadvantages of the use of AI technologies within the field of anaesthesia. Benefits of the application of AI in anaesthesia include an improvement in perioperative risk stratification, personalisation of anaesthetic plans, improvement in efficiency and ultimately reduce healthcare costs. However, reliance on technology may reduce clinical acumen but furthermore there are issues surrounding data quality, privacy as well as legal and ethical concerns, which require further evaluation. Whilst AI within anaesthetic practice holds immense promise, there are substantial challenges which require careful consideration and ongoing evaluation. A collaborative approach will be required from healthcare staff, developers and regulators to promote the safe, responsible, and effective application of AI in anaesthesia practice.
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  • 文章类型: Journal Article
    在澳大利亚的碳足迹中,7%归因于医疗保健。在英国,吸入剂占医疗保健碳足迹的5%。本系统评价旨在确定哪些关于吸入性麻醉剂对环境的影响的教育方法可用于促进行为改变。减少与麻醉相关的碳足迹。本系统综述来自CINAHL的记录,EMBASE,ERIC,JBI和MEDLINE从1970年到2022年3月。搜索确定了589条记录,其中13人在筛选过程后符合资格标准,其中10个记录是会议摘要。教育课程侧重于吸入剂的选择(69%),在维持麻醉期间降低新鲜气体流量(69%),鼓励替代方案,如全静脉麻醉(23%)和/或在转移时关闭气体(8%)。教育课程中最常用的教学技巧是说教式讲座(85%),视觉提示(54%),电子邮件(46%),和对话论坛(31%)。除一项研究外,所有研究都报告了教学课程与行为变化之间的正相关关系,从而导致参与者及其组织使用吸入麻醉药的减少。减少与医疗保健相关的排放。这一系统的审查表明,单一的教育课程以及多重点,关于绿色麻醉主题的多模式教育课程有助于促进行为改变。
    Of the total carbon footprint of Australia, 7% is attributed to healthcare. In the UK, inhalational agents make up 5% of the healthcare carbon footprint. This systematic review aims to determine which methods of education about the environmental impact of inhalational anaesthetic agents can be utilised to promote behaviour change, reducing the anaesthetic-related carbon footprint. This systematic review sourced records from CINAHL, EMBASE, ERIC, JBI and MEDLINE from 1970 to March 2022. The search identified 589 records, 13 of which met eligibility criteria after the screening process, in which 10 of these records were conference abstracts. Education curricula focused on inhalational agent choice (69%), lowering the fresh gas flow during maintenance anaesthesia (69%), encouraging alternatives such as total intravenous anaesthesia (23%) and/or switching off the gas on transfer (8%). The most common teaching techniques utilised in education curricula were didactic lectures (85%), visual prompts (54%), emails (46%), and conversation forums (31%). All but one study reported a positive relationship between teaching sessions and behavioural change resulting in lower inhalational anaesthetic use by participants and their organisations, reducing healthcare-associated emissions. This systematic review has demonstrated that single education sessions as well as multi-focused, multimodal education curricula on the topic of greener anaesthesia can be beneficial in promoting behavioural change.
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  • 文章类型: Journal Article
    困难的气道管理是儿科麻醉的主要挑战之一,特别是在低收入和中等收入国家。
    本研究的目的是探讨儿科插管困难的主要预测因素。
    在这项观察性研究中,我们纳入了所有5岁以下接受气管插管的腹内手术的儿童.根据插管困难的发生率将患者分为两组。然后,我们调查了儿科困难插管的预测因素.
    我们包括217个孩子,在其中10%的患者中观察到困难的插管。预测因素如下:MallampatiIII-IV级(调整后的比值比=2.21;95%置信区间=1.1-6.4),张口受限(调整后的赔率比=2.4;95%置信区间=1.8-3.5),面部畸形(调整后的比值比=2.6;95%置信区间=1.32-7.4)和无肌肉松弛剂麻醉(调整后的比值比=1.8;95%置信区间=1.0-5.1)或无阿片类药物麻醉(调整后的比值比=1.7;95%置信区间=1.01-4.8).
    面部畸形和张口受限是儿童插管困难的预测因素。此外,Mallampati类和麻醉技术似乎也可以预测具有挑战性的插管,这可能会指导我们改变围手术期的做法。
    UNASSIGNED: Difficult airway management is one of the main challenges in paediatric anaesthesia, particularly in low- and middle-income countries.
    UNASSIGNED: The aim of this study was to investigate the main predictors of difficult paediatric intubation.
    UNASSIGNED: In this observational study, we included all children aged less than five years undergoing intra-abdominal surgery with endotracheal intubation. Patients were divided into two groups according to the incidence of difficult intubation. Then, we investigated predictors for difficult paediatric intubation.
    UNASSIGNED: We included 217 children, and difficult intubation was observed in 10% of them. Predictors were as follows: Mallampati III-IV class (adjusted odds ratio = 2.21; 95% confidence interval = 1.1-6.4), limited mouth opening (adjusted odds ratio = 2.4; 95% confidence interval = 1.8-3.5), facial dysmorphia (adjusted odds ratio = 2.6; 95% confidence interval = 1.32-7.4) and anaesthesia without muscle relaxant (adjusted odds ratio = 1.8; 95% confidence interval = 1.0-5.1) or without opioids during crash inductions (adjusted odds ratio = 1.7; 95% confidence interval = 1.01-4.8).
    UNASSIGNED: Facial dysmorphia and limited mouth opening were predictors of difficult intubation in children. Furthermore, it seems that Mallampati class and anaesthesia technique may also predict challenging intubation, which may guide us to change our perioperative practice.
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  • 文章类型: Editorial
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  • 文章类型: Journal Article
    背景技术运行国民健康服务(NHS)的经济负担很高。工作人员应该意识到他们使用的设备的成本,以便有效利用资源,减少浪费,控制支出。然而,本科和初级阶段有限的金融教育导致各级医护人员知识相对贫乏。麻醉学是使用大量设备的专业;因此,我们旨在评估员工对常用消耗品的成本意识。此外,我们旨在评估工作人员对他们使用的设备对财务和环境影响的态度,以及这是否会改变他们的做法。方法在一个月的时间内向MedwayNHSFoundationTrust麻醉部门的工作人员发送了电子调查。受访者被要求估计19种常用麻醉消耗品的成本,如果估计在实际成本的20%以内,则估计为正确。调查结束时,关于他们目前的医疗保健实践对财务和环境的影响以及可能的替代方案,有五个问题需要受访者回答。结果麻醉科共有69名不同角色的受访者。总的来说,只有9.37%的项目被正确估计,便宜的物品通常被高估,更昂贵的物品被低估。总的来说,60%的受访者表示,物品的成本会影响其使用。绝大多数人声称环境影响是一个问题,大多数人会赞成可回收/可重复使用的替代品。结论麻醉人员对常用设备的成本意识较差。在这一领域需要更多的教育和培训,因为对服务成本的有限知识限制了做出当前NHS所需的具有成本效益的选择的能力。
    Background The financial burden of running the National Health Service (NHS) is high. Staff members should be aware of the cost of the equipment they use to enable efficient use of resources, reduce waste, and control spending. However, limited financial education at undergraduate and junior stages has contributed to relatively poor knowledge among healthcare workers at all levels. Anaesthetics is a speciality which uses a large amount of equipment; therefore, we aim to assess the cost awareness among staff for commonly used consumables. Furthermore, we aim to assess staff members\' attitudes towards the financial and environmental impact of the equipment they use and whether this would change their practice. Methodology An electronic survey was sent to staff members from the anaesthetic department of the Medway NHS Foundation Trust during a one-month period. Respondents were asked to estimate the cost of 19 commonly used anaesthetic consumables, with an estimate categorised as correct if it was within 20% of the actual cost. At the end of the survey, there were five questions for respondents to answer regarding the financial and environmental impact of their current healthcare practice and possible alternatives. Results There were 69 respondents within the anaesthetic department from a variety of roles. Overall, only 9.37% of items were estimated correctly, with cheaper items commonly being overestimated and more expensive items being underestimated. Overall, 60% of respondents said the cost of an item would influence their use. The overwhelming majority claimed that the environmental impact was a concern, and most would favour recyclable/reusable alternatives. Conclusions Cost awareness among anaesthetic staff for commonly used equipment is poor. More education and training are necessary in this area as limited knowledge of service costs restricts the ability to make cost-efficient choices which are needed in the current NHS.
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  • 文章类型: Journal Article
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  • 文章类型: Letter
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  • 文章类型: Journal Article
    目的:腹腔局部麻醉作为多模式镇痛方案的一部分,可有效减轻术后疼痛。最近的研究表明,腹腔内利多卡因可能具有镇痛作用。主要目的是确定腹膜内利多卡因对静息术后疼痛评分的影响。
    方法:我们根据系统评价和荟萃分析(PRISMA)的首选报告项目进行了系统评价和荟萃分析。
    方法:MEDLINE数据库,EMBASE,和CENTRAL从成立日期到2023年5月进行搜索。纳入了在接受手术的成年人中比较腹膜内利多卡因和安慰剂的随机临床试验(RCT)。
    结果:我们的系统评价包括24项随机对照试验(n=1,824)。在手术后的成年患者中,腹膜内利多卡因组与休息时(MD:-0.87,95%CI:-1.04至-0.69)和运动时(MD:-0.50,95%Cl:-0.93至-0.08)的术后疼痛评分降低显着相关。它的给药也显着减少了吗啡的消耗(MD:-6.42mg,95%Cl:-11.56至-1.27),降低了需要镇痛的发生率(OR:0.22,95%Cl:0.14至0.35)。腹膜内利多卡因在统计学上减少了恢复正常饮食的时间(MD:0.16天;95%Cl:-0.31至-0.01),并降低术后恶心和呕吐的发生率(OR:0.54,95%Cl:0.39至0.75)。
    结论:在这篇综述中,我们的研究结果应谨慎解释.未来的研究有必要确定在接受手术的成年患者中腹膜内施用利多卡因的最佳剂量。
    OBJECTIVE: The administration of local anaesthesia in intraperitoneal space as part of the multi-modal analgesic regimen has shown to be effective in reducing postoperative pain. Recent studies demonstrated that intraperitoneal lidocaine may provide analgesic effects. Primary objective was to determine the impact of intraperitoneal lidocaine on postoperative pain scores at rest.
    METHODS: We carried out a systematic review and meta-analysis according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA).
    METHODS: Databases of MEDLINE, EMBASE, and CENTRAL were searched from their inception date until May 2023. Randomized clinical trials (RCT) comparing intraperitoneal lidocaine and placebo in adults undergoing surgery were included.
    RESULTS: Our systematic review included 24 RCTs (n = 1,824). The intraperitoneal lidocaine group was significantly associated with lower postoperative pain scores at rest (MD: -0.87, 95% CI: -1.04 to -0.69) and at movement (MD: -0.50, 95% Cl: -0.93 to -0.08) among adult patients after surgery. Its administration also significantly decreased morphine consumption (MD: -6.42 mg, 95% Cl: -11.56 to -1.27), lowered the incidence of needing analgesia (OR: 0.22, 95% Cl: 0.14 to 0.35). Intraperitoneal lidocaine statistically reduced time to resume regular diet (MD: 0.16 days; 95% Cl: -0.31 to -0.01), and lowered postoperative incidence of nausea and vomiting (OR: 0.54, 95% Cl: 0.39 to 0.75).
    CONCLUSIONS: In this review, our findings should be interpreted with caution. Future studies are warranted to determine the optimal dose of administering intraperitoneal lidocaine among adult patients undergoing surgery.
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  • 文章类型: Journal Article
    背景:外周静脉导管(PVC)放置期间多次穿刺会增加并发症的风险。成人静脉穿刺困难评分(A-DIVA量表)存在,但从未在护理算法框架中进行过评估(与新的穿刺条件决策树相关的评分,A-DIVA树)。我们寻求实施导管放置算法以减少每位患者的平均穿刺次数。该算法将根据临床数据分析显示的障碍和杠杆进行调整。将使用该方法的逐步实现来评估该算法的益处。
    方法:794PVC放置将记录在两个包含中心(50%/50%)。在第一阶段,297PVC放置将被收集,将进行16次个人半结构化访谈,以评估各中心的做法。在第二阶段,将记录200个PVC放置以评估A-DIVA量表的影响。中间阶段将允许基于A-DIVA树的初步结果开发。在第三阶段,将记录297个PVC放置以评估算法对每位患者的平均穿刺次数的影响。
    背景:该研究和相关同意书于2023年4月25日由机构审查委员会(Sud-MéditerranéeI)批准,参考号为2023-A00223-42。结果将以原创文章的形式传播,介绍和指导方针。
    背景:NCT05935228。
    BACKGROUND: Multiple punctures during peripheral venous catheter (PVC) placement increase the risk of complications. Scoring for adult difficult intravenous access (A-DIVA Scale) exists but has never been assessed in the framework of a care algorithm (scoring associated with a new decision-making tree for puncture conditions, the A-DIVA Tree). We seek to implement an catheter placement algorithm to decrease the mean number of punctures per patient. The algorithm will be adjusted based on obstacles and levers revealed by the analysis of clinical data. The benefits of the algorithm will be assessed using a step-by-step implementation of the approach.
    METHODS: 794 PVC placements will be recorded in two inclusion centres (50%/50%). In phase I, 297 PVC placements will be collected, and 16 individual semistructured interviews will be conducted to evaluate the centres\' practices. In phase II, 200 PVC placements will be recorded to assess the impact of the A-DIVA Scale alone. The interphase will allow preliminary results based development of the A-DIVA Tree. In phase III, 297 PVC placements will be recorded to assess the impact of the algorithm on the mean number of punctures per patient.
    BACKGROUND: The study and related consent forms were approved by an institutional review board (Comité de Protection des Personnes Sud-Méditerranée I) on 25 April 2023 under reference number 2023-A00223-42. The results will be disseminated in the form of original articles, presentations and guidelines.
    BACKGROUND: NCT05935228.
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  • 文章类型: Journal Article
    背景:Diamedica引气蒸发器2(DDV2)是英国国防医疗服务部门使用的七氟醚蒸发器,用于提供部署的挥发性全身麻醉。防御麻醉系统采用带有涡轮驱动呼吸机的DDV2作为“推倒”蒸发器,从制造商的设计修改。我们调查了七氟醚在不同分钟体积(MV)下的输送,蒸发器设置和温度在这个配置。
    方法:一系列DDV2设置(1%,2%,3%,4%和诱导)和MV(2、4、6和8L/min,每分钟12次通风)在两个环境温度(20和30±3°C)下进行了30分钟的测试。一个补充实验,模拟损伤控制手术期间的麻醉,也完成了,其中DDV2设定为2%,MV为6L/min,持续90分钟。
    结果:在两个实验中,观察到七氟烷递送的两个不同阶段,一个“清洗阶段”,后跟一个“维护期”。洗入阶段通常持续少于5分钟。在维护期间,在低MV和蒸发器设置DDV2提供了一个恒定的输出,而在更高的MV和设置下,蒸汽产量可预见地下降。在20±3°C时,使用临床实践中可能遇到的DDV2设置,七氟醚给药在设定的20%以内.更高的蒸发器设置,MV和温度导致蒸发器设置和试剂输送之间的较大变化。这种变化由DDV2的不完全温度补偿来解释。
    结论:DDV2在一系列设置下可预测地发挥作用,MV和温度。防御麻醉配置中的麻醉递送类似于先前在抽出配置中描述的麻醉递送。该设备被发现是可靠和坚固的。这项实验工作支持继续使用防御麻醉系统来提供和培训已部署的全身麻醉。
    BACKGROUND: The Diamedica Draw-over Vaporiser 2 (DDV2) is the sevoflurane vaporiser used by the UK Defence Medical Services to provide deployed volatile general anaesthesia. The Defence Anaesthesia System employs the DDV2 with a turbine-driven ventilator as a \'push-over\' vaporiser, a modification from the manufacturer\'s design. We investigated sevoflurane delivery at varying minute volumes (MVs), vaporiser settings and temperatures in this configuration.
    METHODS: A range of DDV2 settings (1%, 2%, 3%, 4% and induction) and MVs (2, 4, 6 and 8 L/min at 12 ventilations per minute) were tested at two ambient temperatures (20 and 30±3°C) over 30 min. A supplemental experiment, simulating anaesthesia during damage control surgery, was also completed, where he DDV2 was set to 2% with a 6 L/min MV for 90 min.
    RESULTS: In both experiments, two distinct phases of sevoflurane delivery were noted, a \'wash-in phase\' followed by a \'maintenance period\'. The wash-in phase normally lasted less than 5 min. During the maintenance period at low MVs and vaporiser settings the DDV2 delivered a constant output, while at higher MVs and settings vapour output fell predictably. At 20±3°C, using DDV2 settings likely to be encountered in clinical practice, sevoflurane delivery was within 20% of that set. Higher vaporiser settings, MVs and temperatures resulted in greater variation between vaporiser setting and agent delivery. This variation is explained by the incomplete temperature compensation of the DDV2.
    CONCLUSIONS: The DDV2 functions predictably at a range of settings, MVs and temperatures. Anaesthetic delivery in the defence anaesthesia configuration is like that previously described in the draw-over configuration. The equipment was found to be reliable and robust. This experimental work supports the continued use of the Defence Anaesthesia System for the delivery of and training in deployed general anaesthesia.
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