■老年人经常服用几种药物;因此,不适当的药物处方很常见。处方可能不适当的药物(PIMs)构成严重的风险,因此,我们的目的是评估塔布克老年患者的PIMs,使用2023年啤酒标准。
■进行了回顾性横断面研究,包括2022年6月至2023年5月在两家政府医院收治的年龄≥65岁的老年人,并处方了5种或5种以上药物。PIM使用2023年啤酒标准进行评估。对分类变量和连续变量进行描述性分析。Logistic回归用于评估年龄的影响,性别,使用SPSS版本27对PIM的药物和合并症的数量。
■该研究包括420名患者。参与者的平均年龄为75.52±8.70岁(范围,65-105岁)。女性比例略高(52%)。PIMs的患病率为81.43%,其中35.41%被规定为一次PIM,26.48%的人被开了两个PIM,和17.32%被规定三个PIMs。被认为在老年患者中潜在不适当的药物比例为70.11%,质子泵抑制剂是最常用的处方药(52.99%)。慎用药物的比例为19.55%,利尿剂是最常用的药物(91.43%)。性别和合并症不影响PIMs,但年龄和用药数量显著影响PIMs的可能性。
■PIMs在老年人中普遍存在,并且与年龄和多种用药显著相关。给老年人开药时应谨慎行事。应进行频繁的审计以评估PIM,应告知临床医生,以避免与PIM相关的严重结果。需要启动旨在减少PIM的干预措施。
UNASSIGNED: Older persons are frequently prescribed several medications; therefore, inappropriate medication prescriptions are common. Prescribing potentially inappropriate medications (PIMs) poses a serious risk and hence, we aimed to assess the PIMs in older patients in Tabuk, using the 2023 Beers criteria.
UNASSIGNED: A retrospective cross-sectional study was carried out, including older persons ≥65 years of age admitted in two government hospitals from June 2022 to May 2023, and prescribed with five or more medications. PIMs were assessed using the 2023 Beers criteria. Descriptive analysis was performed for the categorical and continuous variables. Logistic regression was used to assess the influence of age, gender, number of medications and comorbidities on PIMs using SPSS version 27.
UNASSIGNED: The study included 420 patients. The mean age of the participants was 75.52 ± 8.70 years (range, 65-105 years). There was a slightly higher proportion of females (52%). The prevalence of PIMs was 81.43%, where 35.41% were prescribed one PIM, 26.48% were prescribed two PIMs, and 17.32% were prescribed three PIMs. The proportion of medications considered potentially inappropriate among older patients was 70.11%, and proton pump inhibitors were the most commonly prescribed medication (52.99%). The proportion of medications to be used with caution was 19.55%, with diuretics being the most frequently administered medication (91.43%). Gender and comorbidity did not influence PIMs, but age and number of medications significantly influenced the likelihood of PIMs.
UNASSIGNED: PIMs are prevalent among older people and are significantly associated with age and multiple medications. Caution should be exercised while prescribing medications to older persons. Frequent audits should be performed to assess PIMs, and clinicians should be informed of the same to avoid serious outcomes associated with PIMs. Interventions designed to reduce PIM need to be initiated.