目的:本研究旨在通过静脉注射钆增强内耳磁共振成像(ieMRI),研究复发性听音前庭症状患者的内淋巴积水(EH)阳性率。
方法:我们回顾了在奈良医科大学和其他相关医院的眩晕/头晕中心的710例反复出现听前庭症状的连续患者,2014年5月至2020年4月。我们对153例单侧复发性耳蜗前庭症状(rCV)患者进行了IEMRI,51伴有复发性眩晕症状(rVO),84例伴有单侧复发性耳蜗症状(rCO)。
结果:在69.4%的参与者中观察到EH:在rCV组中为81.7%,rVO组的19.6%,rCO组为77.4%。根据疾病持续时间将参与者分为两组:短期和长期组。在短期组(少于4年),在82.3%中观察到EH,42.9%,rCV中71.4%的患者,rVO,和rCO组,分别;在长期组(超过5年)中,在81.1%中观察到EH,10.8%,rCV中81.6%的患者,rVO,和rCO组,分别。
结论:疾病持续时间越长,rCO患者的EH阳性率越大,在那些有RVO的人中更小,并且在具有rCV的那些中保持不变。尽管IEMRI无法在梅尼埃病中以100%的准确性检测到EH,目前有复发性听觉前庭症状患者的病理学统计可能有助于考虑基于病理学的治疗策略.
OBJECTIVE: This study aimed to investigate the endolymphatic hydrops (EH)-positivity rates among patients with recurrent audiovestibular symptoms using intravenous injection of gadolinium-enhanced inner ear magnetic resonance imaging (ieMRI).
METHODS: We reviewed 710 successive patients with recurrent audiovestibular symptoms at the Vertigo/Dizziness Center of Nara Medical University and other related hospitals, between May 2014 and April 2020. We performed ieMRI on 153 patients with unilateral recurrent cochleovestibular symptoms (rCV), 51 with recurrent vertigo symptoms (rVO), and 84 with unilateral recurrent cochlear symptoms (rCO).
RESULTS: EH was observed in 69.4% of the participants: 81.7% in the rCV group, 19.6% in the rVO group, and 77.4% in the rCO group. The participants were divided into two groups according to the disease duration: short-duration and long-duration groups. In the short-duration group (less than 4 years), EH was observed in 82.3%, 42.9%, and 71.4% of the patients in rCV, rVO, and rCO groups, respectively; in the long-duration group (more than 5 years), EH was observed in 81.1%, 10.8%, and 81.6% of the patients in rCV, rVO, and rCO groups, respectively.
CONCLUSIONS: The longer the duration of the disease, the larger the EH-positivity rates in patients with rCO, smaller in those with rVO, and unchanged in those with rCV. Although ieMRI could not detect EH with 100% accuracy in Ménière\'s disease, the present pathological statistics of patients with recurrent audiovestibular symptoms might be helpful in considering the pathology-based treatment strategy.