目的:研究12周运动音乐(M2M)干预对卒中后患者身体和社会心理结局的影响。
方法:双臂随机对照试验。
方法:以社区为基础的健身设施。
方法:将18至65岁中风的参与者(N=47)随机分为M2M(n=23)或候补对照(n=24)。
方法:M2M参与者每周完成3次60分钟的锻炼,为期12周。控件通过邮件每两周收到一次教育通讯。
方法:主要结果包括六分钟步行测试(6MWT,以米为单位),五次坐立测试(FTSST,以秒为单位)和定时上行和上行(TUG,以秒为单位)。次要结果是使用患者报告结果测量信息系统疲劳和疼痛干扰简表8a的自我报告测量。在基线和干预后收集结果。分析涉及描述性统计和调整后的线性混合模型。
结果:针对各自的基线值和人口统计学变量进行调整的混合模型显示,M2M参与者的6MWT距离更长(最小二乘均值差异[LSM],14.5;95%置信区间[CI],-12.9至42.0),更多FTSST时间(LSM,2.0;95%CI,-4.5至8.5),和较少的疲劳(LSM,-3.0;95%CI,-7.2至1.2)与干预后的对照组相比。当控制基线TUG和人口统计学变量时,6MWT距离增加较大(LSM,37.9;95%CI,-22.7至98.6),较低的FTSST时间(LSM,-6.1;95%CI,-18.5至6.2),和疲劳减少(LSM,-6.5;与对照组相比,M2M组中的95%CI,-13.1至0.2)。观察到中等效应大小可改善6MWT(d=0.6),FTSST(d=-0.6),和疲劳(d=-0.6)。在TUG时间和疼痛干扰的改变方面没有组间差异,具有微不足道的效应大小(d=-0.1)。
结论:M2M可能是中风成人的一种有价值的运动形式。未来的研究需要确定最佳的运动剂量,以改善该人群的健康和功能。
OBJECTIVE: To investigate the effects of a 12-week movement-to-music (M2M) intervention on physical and psychosocial outcomes in people poststroke.
METHODS: Two-arm randomized controlled trial.
METHODS: A community-based fitness facility.
METHODS: Participants (N=47) with stroke between 18 and 65 years old were randomized to M2M (n=23) or waitlist control (n=24).
METHODS: Participants in M2M completed 3 60-minute exercise sessions per week for 12 weeks. Controls received biweekly educational newsletters via mail.
METHODS: Primary outcomes included Six-Minute Walk Test (6MWT, in meters), Five Times Sit-to-Stand Test (FTSST, in seconds) and Timed Up and Go (TUG, in seconds). Secondary outcomes were self-reported measures using Patient-Reported Outcomes Measurement Information System Fatigue and Pain Interference Short Form 8a. Outcomes were collected at baseline and postintervention. Analyses involved descriptive statistics and adjusted linear mixed models.
RESULTS: Mixed models adjusted for the respective baseline values and demographic variables showed that M2M participants had longer 6MWT distance (least square mean difference [LSM], 14.5; 95% confidence interval [CI], -12.9 to 42.0), more FTSST time (LSM, 2.0; 95% CI, -4.5 to 8.5), and less fatigue (LSM, -3.0; 95% CI, -7.2 to 1.2) compared with controls postintervention. When controlling for baseline TUG and demographic variables, there was a larger increase in 6MWT distance (LSM, 37.9; 95% CI, -22.7 to 98.6), lower FTSST time (LSM, -6.1; 95% CI, -18.5 to 6.2), and decrease in fatigue (LSM, -6.5; 95% CI, -13.1 to 0.2) in the M2M group compared with controls. Moderate effect sizes were observed for improving 6MWT (d=0.6), FTSST (d=-0.6), and fatigue (d=-0.6). There was no group difference in change in TUG time and pain interference, with trivial effect sizes (d=-0.1).
CONCLUSIONS: M2M may be a valuable exercise form for adults with stroke. Future studies are needed to determine optimal exercise doses for improving health and function in this population.