寻常痤疮(AV),皮脂腺中的皮脂产生过多和痤疮杆菌增殖,显着影响身心健康。最近的治疗进展集中在皮脂腺的选择性光热解。这篇综述评估了两种创新疗法:1726nm激光和纳米粒子辅助激光治疗。我们使用主要术语“寻常痤疮”或“痤疮”和“激光”对PubMed和Embase进行了全面搜索,\"\"光热疗法,\"\"纳米粒子,\"\"治疗,“或”1726nm激光。“纳入标准是在同行评审的期刊上以英文发表的文章,重点是通过针对皮脂腺来治疗AV,产生11项研究。金纳米粒子,与800纳米激光一起使用,1064-nmNd:YAG激光器,或光气动装置,和铂纳米粒子与1450纳米二极管激光,显示痤疮病变的严重程度和数量显着改善,安全,患者满意度。1726nm激光治疗也显示出相当大的损伤减少和耐受性,具有最小的副作用,如红斑和水肿。它的效率归功于它的简短,有效靶向皮脂腺的高功率脉冲,提供精确的治疗与更少的副作用相比,低功率脉冲。使用纳米粒子辅助激光治疗或1726nm激光的选择性光热分解为传统AV治疗提供了有希望的替代方案,展示疗效和高患者满意度。1726纳米激光流线治疗,但涉及新的设备成本,虽然纳米粒子辅助疗法很好地整合到现有的设置中,但依赖于外部药物,不适合某些过敏。未来的研究应包括长期研究和比较分析。治疗方式的选择应考虑患者的喜好,成本影响,以及特定疗法的可用性。
Acne vulgaris (AV), characterized by excessive sebum production and Cutibacterium acnes proliferation in the sebaceous glands, significantly impacts physical and psychological health. Recent treatment advancements have focused on selective photothermolysis of sebaceous glands. This review evaluates two innovative therapies: the 1726-nm laser and nanoparticle-assisted laser treatments. We conducted a comprehensive search of PubMed and Embase using the primary terms \"acne vulgaris\" or \"acne\" AND \"laser,\" \"photothermal therapy,\" \"nanoparticles,\" \"treatment,\" or \"1726 nm laser.\" Inclusion criteria were articles published in English in peer-reviewed journals that focused on treating AV through targeting the sebaceous glands, yielding 11 studies. Gold nanoparticles, used with 800-nm laser, 1064-nm Nd: YAG laser, or photopneumatic device, and platinum nanoparticles with 1450-nm diode laser, showed notable improvements in severity and number of acne lesions, safety, and patient satisfaction. The 1726-nm laser treatments also showed considerable lesion reduction and tolerability, with minimal side effects such as erythema and edema. Its efficiency is credited to its short, high-power pulses that effectively target sebaceous glands, offering precise treatment with fewer side effects compared to lower-power pulses. Selective photothermolysis using nanoparticle-assisted laser therapy or the 1726-nm laser offers a promising alternative to conventional AV treatments, showcasing efficacy and high patient satisfaction. The 1726-nm laser streamlines treatment but involves new equipment costs, while nanoparticle-assisted therapy integrates well into existing setups but relies on external agents and is unsuitable for certain allergies. Future research should include long-term studies and comparative analyses. The choice of treatment modality should consider patient preferences, cost implications, and availability of specific therapies.