UNASSIGNED:根据2020年的职业事故状况分析,在1,180例职业死亡中,463例患者由心血管疾病(CVD)引起。应根据职业安全和健康标准的规定,定期评估工人的CVD风险,以预防与工作有关的CVD。然而,之前没有研究涉及风险和死亡率.因此,这项纵向研究旨在评估一般健康体检的10年心血管风险与死亡率之间的关系.
UNASSIGNED:该研究包括545,859名参与者,他们从2002年1月1日至2017年12月31日访问了KangbukSamsungTotalHealthcareCenters。我们对参与者进行了10年的心血管风险评估,并将风险分为4组(低,中度,高,并且非常高)。该研究使用韩国国家统计局截至2019年12月31日的生存状况死亡数据作为结果变量,根据国际疾病分类,确定了第10次修订(ICD-10)。统计学分析采用Cox比例风险回归分析,以首次访视至死亡之日或2019年12月31日的时间总和作为时间尺度.我们还对基线和性别的年龄进行了分层分析。
未经评估:在5,253,627.9人年期间,总共发生了4,738例死亡和654例心血管死亡。当将低风险组设置为参考时,在多变量调整模型中,中等风险组总死亡率的风险比(HR)(95%置信区间[CI])为3.36(2.87-3.95),11.08(9.27-13.25)在高风险组中,在极高风险组中为21.20(17.42-25.79),所有这些都有统计学意义。在心血管死亡中,根据风险分类的差异更为明显.HR(95%CI)为8.57(4.95-14.83),38.95(21.77-69.69),每组78.81(42.62-145.71)。根据年龄和性别进行亚组分析的结果,在高危人群中,全因死亡率和心血管死亡率的HR往往较高.
UNASSIGNED:这项大规模纵向研究证实,死亡风险随着一般健康检查的10年心血管风险而增加。
UNASSIGNED: According to the occupational accident status analysis in 2020, of 1,180 occupational deaths, 463 were caused by cardiovascular disease (CVD). Workers should be assessed for CVD risk at regular intervals to prevent work-related CVD in accordance with the rules on occupational safety and health standards. However, no previous study has addressed risk and mortality. Therefore, this longitudinal study was conducted to evaluate the relationship between 10-year cardiovascular risk of the general health checkup and mortality.
UNASSIGNED: The study included 545,859 participants who visited Kangbuk Samsung Total Healthcare Centers from January 1, 2002, to December 31, 2017. We performed 10-year cardiovascular risk assessment for the participants and the risk was divided into 4 groups (low, moderate, high, and very high). The study used death data from the Korea National Statistical Office for survival status as an outcome variable by December 31, 2019, and the cause of death based on the International Classification of Diseases, 10th Revision (ICD-10) was identified. Statistical analysis was performed using Cox proportional hazards regression analysis, and the sum of the periods from the first visit to the date of death or December 31, 2019, was used as a time scale. We also performed a stratified analysis for age at baseline and sex.
UNASSIGNED: During 5,253,627.9 person-years, 4,738 overall deaths and 654 cardiovascular deaths occurred. When the low-risk group was set as a reference, in the multivariable-adjusted model, the hazard ratios (HRs) (95% confidence interval [CI]) for overall mortality were 3.36 (2.87-3.95) in the moderate-risk group, 11.08 (9.27-13.25) in the high-risk group, and 21.20 (17.42-25.79) in the very-high-risk group, all of which were statistically significant. In cardiovascular deaths, the difference according to the risk classification was more pronounced. The HRs (95% CI) were 8.57 (4.95-14.83), 38.95 (21.77-69.69), and 78.81 (42.62-145.71) in each group. As a result of a subgroup analysis by age and sex, the HRs of all-cause mortality and cardiovascular mortality tended to be higher in the high-risk group.
UNASSIGNED: This large-scale longitudinal study confirmed that the risk of death increases with the 10-year cardiovascular risk of general health checkup.