传染性软疣(MC)是儿童常见的病毒感染,免疫受损,和性活跃的成年人。它通常的临床表现是2-5毫米,发白或肤色的丘疹,有光泽的表面和中心的脐带,通常聚集并随机分布在皮肤表面。皮肤镜检查显示黄白色多叶结构伴外周毛细血管扩张。诊断通常由皮肤镜检查提供临床支持。然而,在某些情况下,炎症表现可能与这种感染有关,并且可以模仿其他皮肤病,使诊断困难,导致不必要的治疗。本文的目的是描述与MC感染相关的主要皮肤反应,以便为处理这些疾病的临床医生提供诊断和初始管理工具。报告的表现包括BOTE标志,周围性湿疹,Gianotti-Crosti综合征样反应,ID反应,环带红斑离心机,多形性红斑,毛囊炎,白色光环,和非典型表现(巨大,传播,坏死,息肉状,结节性病变,假性囊肿,脓肿)。在具有上述临床表现的儿科患者中,在鉴别诊断中,应考虑感染传染性痘病毒的软体动物,在某些情况下,应转诊给皮肤科医生。
Molluscum contagiosum (MC) is a common viral infection in children, immunocompromised, and sexually active adults. Its usual clinical presentation is 2-5 mm, whitish or skin-colored papules, with a shiny surface and central umbilication, generally clustered and randomly distributed over the skin surface. Dermoscopy reveals yellowish-white polylobulated structures with peripheral telangiectasia. Diagnosis is usually clinical supported by dermoscopy. However, in some cases, inflammatory manifestations can be associated with this infection and can mimic other dermatological conditions, making the diagnosis difficult and leading to unnecessary treatments. The objective of this article is to describe the main skin reactions associated with MC infection in order to provide a diagnostic and initial management tool for clinicians dealing with these conditions. Reported manifestations include the BOTE sign, perilesional eczema, Gianotti-Crosti syndrome-like reaction, ID reaction, erythema annulare centrifugum, erythema multiforme, folliculitis, white halo, and atypical manifestations (giant, disseminated, necrotic, polypoidal, and nodular lesions, pseudocysts, abscesses). In pediatric patients with the clinical manifestations described above, infection by molluscum contagiosum pox virus should be considered among the differential diagnoses, and referral to a dermatologist should be made in selected cases.