eye diseases

眼部疾病
  • 文章类型: Journal Article
    Rheumatic diseases are a large group of conditions of various origins, predominantly systemic in nature, with persistent or transient joint syndrome and involvement of other organs and systems, including the eyes. Many rheumatic diseases are characterized by specific types of ocular inflammation, which manifests through its localization, symmetry, and clinical features.
    Ревматические заболевания — большая группа различных по происхождению болезней преимущественно системного характера, протекающих со стойким или преходящим суставным синдромом и вовлечением в воспалительный процесс других органов и систем, в том числе глаз. Многие ревматические заболевания характеризуются определенным типом воспаления глаз, что проявляется его локализацией, симметричностью и клиническими особенностями.
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  • 文章类型: News
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  • 文章类型: Journal Article
    目的:光学相干断层扫描(OCT)和OCT血管造影(OCTA)在眼科疾病的诊断中有着广泛的应用。本研究旨在提供眼科OCT和OCT血管造影的全面文献计量分析。
    方法:我们从WebofScienceCoreCollection检索了2003年至2022年有关眼科OCT和OCTA的出版物,并使用文献计量工具对分布进行了分析和可视化,趋势,和热点。
    结果:总计,选择了来自106个国家/地区的48,160名作者撰写的20,817篇文章。出版物数量大幅增加。在过去的二十年里,美国是生产力最高的国家,获得最高的引用。最富有成效的期刊是调查性眼科和视觉科学,并且获得了最多的引用。Moorfields眼科医院是生产力最高的机构。BandelloF发表的论文最多,而SpaideRF是最高被引作者。太空射频,2011年,AMJ眼科是被引用最多的文献。\"OCT\",“青光眼”和“OCTA”是过去二十年来的三个热点。“血管密度”和“深度学习”将成为未来的研究热点。
    结论:过去二十年来对关键词的眼科OCT和OCTA研究的文献计量分析,作者,引文,热点和趋势将为全球研究人员提供未来研究与合作的宝贵信息。
    OBJECTIVE: Optical coherence tomography (OCT) and OCT angiography (OCTA) are widely used in the diagnosis of ophthalmic diseases. This study aims to provide a comprehensive bibliometric analysis of ophthalmologic OCT and OCT angiography.
    METHODS: We retrieved publications on ophthalmic OCT and OCTA from 2003 to 2022 from the Web of Science Core Collection and used bibliometric tools to analyze and visualize the distribution, trend, and hotspots.
    RESULTS: In total, 20,817 articles written by 48,160 authors from 106 countries were selected. The number of publications has significantly increased. In the last two decades, the USA was the most productive country and received the highest citations. The most productive journal was Investigative Ophthalmology and Visual Science and received the highest number of citations. Moorfields Eye Hospital was the most productive institution. Bandello F published the most papers, while Spaide RF was the highest cited author. SPAIDE RF, 2011, AM J Ophthalmology was the most cited document. \"OCT\", \"glaucoma\" and \"OCTA\" were three hotspots in the last two decades. \"Vessel density\" and \"deep learning\" would be research hotspots in the future.
    CONCLUSIONS: The bibliometric analysis of ophthalmic OCT and OCTA research over the past two decades on keywords, authors, citations, hotspots and trends will provide global researchers with valuable information for future research and cooperation.
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  • 文章类型: Journal Article
    目的:本研究调查了眼部护理方案(ECP)对重症监护病房(ICU)患者的影响。
    方法:本研究采用随机对照设计。参与者是符合纳入标准并进入ICU的患者(实验组36例,对照组38例)。实验组接受ECP,而对照组接受标准的眼部护理,从入院后的第二天开始,为期10天。ECP根据下眼睑结膜和角膜的暴露程度将眼睑阻塞程度分为三个阶段。协议包括用生理盐水纱布清洗,服用眼药水,应用有机硅和聚氨酯薄膜,如有必要,建议咨询眼科医生。通过分析泪液体积来评估ECP的有效性,充血,化疗,和眼睛放电。使用SPSS27.0进行数据分析,采用Mann-WhitneyU检验和广义估计方程。
    结果:在第5天,与对照组相比,实验组双眼的泪液体积显着增加。然而,在充血的发生率上没有观察到统计学上的显著差异,化疗,并在干预的第5天和第10天出现眼部分泌物。
    结论:本研究中ECP的应用增加了ICU患者的泪液体积,从而减少眼睛干涩引起的不适。它有可能防止并发症,例如由于泪液体积减少而导致的眼球表面损伤。
    OBJECTIVE: This study investigated the effects of an eye care protocol (ECP) on patients in the intensive care unit (ICU).
    METHODS: This study utilized a randomized controlled design. Participants were patients who met the inclusion criteria and were admitted to the ICU (36 in the experimental group and 38 in the control group). The experimental group received an ECP, while the control group received standard eye care, starting the day after admission, for a duration of 10 days. The ECP classifies the degree of eyelid obstruction into three stages based on the degree of exposure to the lower eyelid conjunctiva and cornea. The protocol included cleansing with normal saline gauze, administering eye drops, applying silicone and polyurethane films, and recommending consultation with an ophthalmologist if necessary. The effectiveness of ECP was assessed by analyzing tear volume, hyperemia, chemosis, and eye discharge. Data analysis was conducted using SPSS 27.0, employing the Mann-Whitney U-test and generalized estimating equations.
    RESULTS: On day 5, the experimental group demonstrated a significant increase in tear volume in both eyes compared with the control group. However, no statistically significant differences were observed in the incidence of hyperemia, chemosis, and eye discharge on days 5 and 10 of the intervention.
    CONCLUSIONS: The application of the ECP in this study increased tear volume in ICU patients, thereby reducing discomfort caused by dry eyes. It has the potential to prevent complications such as damage to the surface of the eyeball resulting from decreased tear volume.
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  • 文章类型: Letter
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  • 文章类型: Journal Article
    这项研究的目的是评估COVID-19对眼部疾病的影响以及COVID-19大流行前后危险因素的变化。这项研究是使用韩国国家健康和营养检查调查(KNHANES)2015-2021年的数据进行的,这是一项国家横断面健康检查和调查。使用卡方检验和逻辑回归分析确定眼部疾病与危险因素之间的关联。进行双变量调整逻辑回归分析,以检查比值比(OR)和95%置信区间(CI),以评估COVID-19对眼部疾病的影响。将个体分为两个年龄组(<60岁和≥60岁)。共有50158人被确诊,其中7270人被诊断患有白内障,921患有青光眼,439例年龄相关性黄斑变性(AMD)。白内障的危险因素是COVID-19大流行(OR1.161),高血压(OR1.608),糖尿病(或1.573),血脂异常(OR1.167),行程(OR1.272),和抑郁症(或1.567)。AMD的危险因素是COVID-19大流行(OR1.600),血脂异常(OR1.610),和抑郁症(或1.466)。青光眼的危险因素为高血压(OR1.234),血脂异常(OR1.529),糖尿病(OR1.323),和抑郁症(OR1.830)。COVID-19大流行是白内障和AMD的危险因素,但不是青光眼。白内障和AMD可能更受获得的健康状况或环境的影响。
    The aim of this study was to evaluate the impact of COVID-19 on ocular diseases and changes in risk factors before and after the COVID-19 pandemic. This study was conducted using data from the Korea National Health and Nutrition Examination Survey (KNHANES) 2015-2021, a national cross-sectional health examination and survey. Associations between ocular diseases and risk factors were determined using the chi-squared test and logistic regression analysis. Bivariable adjusted logistic regression analysis was performed to examine the odds ratio (OR) and 95% confidence interval (CI) to evaluate of the impact of COVID-19 on ocular diseases. Individuals were divided into two age groups (< 60 and ≥ 60 years). A total of 50,158 people were diagnosed, of whom 7270 were diagnosed with cataract, 921 with glaucoma, and 439 with age-related macular degeneration (AMD). Risk factors for cataract were COVID-19 pandemic (OR 1.161), hypertension (OR 1.608), diabetes (OR 1.573), dyslipidemia (OR 1.167), stroke (OR 1.272), and depression (OR 1.567). Risk factors for AMD were COVID-19 pandemic (OR 1.600), dyslipidemia (OR 1.610), and depression (OR 1.466). Risk factors for glaucoma were hypertension (OR 1.234), dyslipidemia (OR 1.529), diabetes (OR 1.323), and depression (OR 1.830). The COVID-19 pandemic was a risk factor for cataracts and AMD, but not for glaucoma. Cataracts and AMD may be more influenced by the acquired health conditions or the environment.
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  • 文章类型: Journal Article
    目的:克鲁松综合征是一种由10号染色体FGFR2基因突变引起的先天性遗传性疾病。它通常以常染色体显性遗传,是最常见的颅骨融合综合征之一。本文重点介绍克鲁松综合征的眼科相关方面,以帮助诊断和制定个性化治疗方案。
    方法:通过使用布尔运算符AND和OR对PubMed电子数据库进行组合系统搜索,选择以下关键字:\"Crouzon\",“颅骨融合症”,\"eye\",\"oculus\",“眼”,“眼科”,“眼科”,“眼科”,\"地球仪\",\"轨道\",“眼球突出”,\"驱魔\",“角膜病变”,“视觉”等。在对这些文章进行初步筛选后,重复文献被排除。
    结果:选择了47篇文章。本文介绍了眼部表现,克鲁松综合征可能的发病机制及治疗进展。
    结论:克鲁宗综合征的眼部异常发生率很高,比如浅轨道,眼球突出,超端粒,暴露性角膜病变,斜视,视神经病变,屈光不正,青光眼,等。这些眼部异常的发病机制与眼眶畸形有关。目前,大多数治疗方法都旨在弥补异常的解剖结构。
    OBJECTIVE: Crouzon syndrome is a congenital genetic disease caused by mutations of the FGFR2 gene on chromosome 10. It is usually inherited in an autosomal dominant pattern and is one of the most common types of craniosynostosis syndromes. This article focuses on the ophthalmology-related aspects of Crouzon syndrome in order to help diagnose and develop personalized treatment plans.
    METHODS: A combined systematic search of PubMed electronic database by using Boolean operators AND and OR was conducted, choosing the following keywords: \"Crouzon\", \"craniosynostosis\", \" eye \", \" oculus \", \" ocular \", \" ophthalmic \", \" ophthalmologic \", \" ophthalmology \", \" globe \", \" orbit \", \" exophthalmos \", \" exorbitism \", \" keratopathy \", \" visual \" etc. After the initial screening of these articles, repetitive literatures were excluded.
    RESULTS: 47 articles were selected. This article introduces the ocular manifestations, possible pathogenesis and treatment progress in Crouzon syndrome.
    CONCLUSIONS: The incidence of ocular abnormalities in Crouzon syndrome is very high, such as shallow orbits, exophthalmos, hypertelorism, exposure keratopathy, strabismus, optic neuropathy, ametropia, glaucoma, etc. The pathogenesis of these ocular abnormalities is related to orbital deformities. Most of the treatments are aimed at compensating the abnormal anatomic structure at present.
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  • 文章类型: Journal Article
    背景:眼科临床数据的无缝互操作性有利于通过整合来自各种来源的数据来改善患者护理和推进研究。这种整合增加了可用的数据量,导致更强大的统计分析,提高人工智能模型的准确性和可靠性。然而,缺乏一致性,统一的数据格式和含义(语法和语义互操作性)对共享眼科数据提出了重大挑战。
    方法:健康等级7(HL7)快速医疗保健互操作性资源(FHIR),医疗保健数据交换的标准,成为一个有希望的解决方案。为了促进研究中的跨站点数据交换,德国医学信息学计划(MII)开发了基于FHIR的核心数据集(CDS)。
    结果:这项工作调查了MIICDS规范在交换眼科临床数据方面的适用性,这些数据是训练和验证用于预测视力的特定机器学习模型所必需的。在跨学科合作中,我们对所需的眼科临床数据进行了鉴定和分类,并探讨了使用MIICDS规范将其映射到FHIR的可能性.
    结论:我们发现当前的FHIRMIICDS规范并不能完全适应我们研究的眼科临床数据,表明创建扩展模块是必不可少的。
    BACKGROUND: Seamless interoperability of ophthalmic clinical data is beneficial for improving patient care and advancing research through the integration of data from various sources. Such consolidation increases the amount of data available, leading to more robust statistical analyses, and improving the accuracy and reliability of artificial intelligence models. However, the lack of consistent, harmonized data formats and meanings (syntactic and semantic interoperability) poses a significant challenge in sharing ophthalmic data.
    METHODS: The Health Level 7 (HL7) Fast Healthcare Interoperability Resources (FHIR), a standard for the exchange of healthcare data, emerges as a promising solution. To facilitate cross-site data exchange in research, the German Medical Informatics Initiative (MII) has developed a core data set (CDS) based on FHIR.
    RESULTS: This work investigates the suitability of the MII CDS specifications for exchanging ophthalmic clinical data necessary to train and validate a specific machine learning model designed for predicting visual acuity. In interdisciplinary collaborations, we identified and categorized the required ophthalmic clinical data and explored the possibility of its mapping to FHIR using the MII CDS specifications.
    CONCLUSIONS: We found that the current FHIR MII CDS specifications do not completely accommodate the ophthalmic clinical data we investigated, indicating that the creation of an extension module is essential.
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