epiphyses

附生
  • 文章类型: Journal Article
    全年参与涉及高水平重复运动的青年运动会营造一个可能发生过度使用伤害的环境。骨phy原发性应力损伤(PSIs),骨骼不成熟的运动员是独一无二的,是一个特别关注的问题,考虑到它们对增长的潜在干扰。最初在小联盟棒球运动员中观察到,现在已知这些损伤会影响肩膀周围的长骨,弯头,手腕,手,膝盖,脚踝,以及参与各种体育活动的未成熟运动员的脚。本文从流行病学和放射学角度对青少年运动中的骨phyPSI的范围和分布进行了研究。我们还回顾了一个新的框架,以了解导致这些损伤的病理生理机制。该信息对于骨phy病PSIs的早期识别和设计可以减少延迟诊断和长期发病率的预防措施至关重要。预防和减少对骨phy生长板的损伤至关重要,因为损伤和功能障碍会导致终身发病率和过早发生骨关节炎的风险。
    Year-round participation in youth sport that involves high levels of repetitive movement fosters an environment in which overuse injuries are likely to occur. Epiphyseal primary physeal stress injuries (PSIs), unique to skeletally immature athletes, are a particular concern, given their potential for growth disturbance. Initially observed in Little League baseball players, these injuries are now known to affect the long bones around the shoulder, elbow, wrist, hand, knee, ankle, and foot of skeletally immature athletes involved in a variety of sport activities.This article offers an epidemiological and radiologic perspective on the extent and distribution of epiphyseal PSIs in youth sport. We also review a novel framework for understanding the pathophysiologic mechanisms causing these injuries. This information is essential for the early identification of epiphyseal PSIs and devising preventive measures that can reduce a delayed diagnosis and long-term morbidity. Preventing and reducing injury to the epiphyseal growth plates is essential because impairment and dysfunction can result in lifelong morbidity and a risk of premature osteoarthritis.
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  • 文章类型: Case Reports
    背景:保肢手术是治疗儿童涉及主要关节相邻部位的骨恶性肿瘤的重要方法。这项技术可以保护肢体功能,尤其是下肢.然而,以合理的尺度切除肿瘤块后重建胫骨近端以保留膝关节总数并减少肢体长度差异是一项挑战。
    方法:我们介绍一例胫骨近端骨肉瘤。在接受了扩大的肿瘤切除术后,儿童的胫骨近端使用保留骨phy的假体置换进行了重组。该程序保留了受影响肢体的膝关节的整个关节表面和生长板,并为保留受影响肢体的功能和生长潜力提供了可行的替代方案。自初次手术以来,在3.5年的随访中,患者保持无病状态,并且观察到正常的肢体运动功能。
    结论:保留骨phy使我们的患者在保肢手术后表现出更好的肢体功能,因为他的膝关节没有受损,并且减少了肢体长度差异。我们认为,保留骨phy的假体置换可以为长骨局灶性恶性肿瘤切除后的重建提供最佳策略。
    BACKGROUND: Limb salvage surgery is an important method for treating malignant tumors of the bone involving the adjacent parts of the major joints in children. This technique allows for preservation of limb function, especially in the lower limb. However, the reconstruction of the proximal end of the tibia after removing the tumor mass with a rational scale to preserve the total knee joint and reduce limb length discrepancy presents a challenge.
    METHODS: We present a case of osteosarcoma of the proximal tibia. After being treated with an extended tumor resection, the proximal tibia of the child was restructured using endoprosthetic replacement with epiphyseal preservation. This procedure preserves the entire articular surface and growth plate of the knee joint of the affected limb and provides a feasible alternative protocol for retaining the function and growth potential of the affected limb. The patient remained disease-free and normal limb motor function was observed during the 3.5 year follow-up since the initial surgery.
    CONCLUSIONS: Preservation of the epiphysis enabled our patient to perform better limb function after limb-saving surgery as a result of his undamaged knee joint and minimized limb-length discrepancy. We believe that endoprosthetic replacement with preservation of the epiphysis can provide the best strategy for reconstruction after resection of focal malignant tumors in long bones without epiphytic involvement.
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  • 文章类型: Journal Article
    目的:本系统综述和荟萃分析的主要目的是评估3种不同的上皮固定技术在儿科人群中使用植入物治疗腿长差异(LLD)的成功率。次要目标是解决有效性(最终LLD)和报告的订书钉并发症,张力带板(TBP),和经皮表皮固定术螺钉(PETS)。
    方法:在这篇系统综述中,我们搜索了MEDLINE(PubMed),Embase,科克伦图书馆,WebofScience和Scopus对骨骼未成熟的LLD患者进行了研究。所提取的结果类别是上生理固定术的有效性(LLD测量术前/术后,成功/不成功)和按严重程度分级的并发症。
    结果:纳入44项研究(2,184例患者)。455接受了PETS的表皮固定术,578例TBP患者,和1,048个钉书钉。据报道,PETS(9项研究)成功的上皮外皮固定术占76%(95%置信区间[CI]61-89),67%(CI54-79)伴有TBP(10项研究),51%(CI28-65)患有布朗特订书钉(8项研究)。根据汇总分析,PETS的严重并发症发生率为7%,17%的TBP,布朗特主食为16%。据报道,PETS后有4%的人出现角畸形,TBP后10%,在布朗特主食之后还有17%。
    结论:我们的研究结果表明,采用PETS植入物的上皮组织固定术是最成功的技术。PETS的成功率更高,更少的严重并发症,角畸形比例较低。
    OBJECTIVE: The primary aim of this systematic review and meta-analysis was to evaluate the success rate of 3 different epiphysiodesis techniques with implant usage for the treatment of leg-length discrepancy (LLD) in the pediatric population. The secondary aim was to address effectiveness (final LLD) and the reported complications of staples, tension-band plates (TBP), and percutaneous epiphysiodesis screws (PETS).
    METHODS: In this systematic review we searched MEDLINE (PubMed), Embase, Cochrane Library, Web of Science and Scopus for studies on skeletally immature patients with LLD treated with epiphysiodesis with an implant. The extracted outcome categories were effectiveness of epiphysiodesis (LLD measurements pre-/postoperatively, successful/unsuccessful) and complications that were graded on severity.
    RESULTS: 44 studies (2,184 patients) were included. 455 underwent epiphysiodesis with PETS, 578 patients with TBP, and 1,048 with staples. Successful epiphysiodesis was reported in 76% (95% confidence interval [CI] 61-89) with PETS (9 studies), 67% (CI 54-79) with TBP (10 studies), and 51% (CI 28-65) with Blount staples (8 studies). From pooled analysis, the severe complications rate was 7% for PETS, 17% for TBP, and 16% for Blount staples. Angular deformity was reported in 4% after PETS, 10% after TBP, and 17% after Blount staples.
    CONCLUSIONS: Our results showed that epiphysiodesis with PETS implants was the most successful technique. PETS had a higher success rate, fewer severe complications, and a lower proportion with angular deformity.
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  • 文章类型: English Abstract
    Epiphysiolysis and epiphyseal fractures of the distal femur and proximal tibia are an extremely rare entity, but due to their far-reaching consequences with associated functional restrictions of the knee joint, they must be recognized and treated thoroughly. Complete and correct diagnosis is essential and, diagnostically speaking and in addition to standard x‑rays in two planes, the threshold for cross-sectional imaging examination techniques should be low. A conservative treatment attempt is possible for undisplaced fractures, but surgical retention and stabilization using wires and screws is usually indicated. Growth disorders often and inevitably occur after such injuries. Clinical monitoring of complications only ends once growth is complete.
    UNASSIGNED: Epiphysiolysen und Epiphysenfrakturen von distalem Femur und proximaler Tibia sind eine äußerst seltene Entität, müssen aufgrund ihrer weitreichenden Konsequenzen mit einhergehenden Funktionseinschränkungen des Kniegelenks aber obligat erkannt und richtig behandelt werden. Die richtige Diagnostik ist unverzichtbar und beinhaltet neben dem Standardröntgen in zwei Ebenen auch niederschwellig schnittbildgebende Untersuchungstechniken. Ein konservativer Therapieversuch ist bei undislozierten Frakturen möglich, meist ist aber die operative Retention und Stabilisierung mittels Drähten und Schrauben indiziert. Wachstumsstörungen treten häufig und schicksalshaft nach solchen Verletzungen auf. Die klinische Überwachung der Komplikationen ist erst mit dem abgeschlossenen Wachstum beendet.
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  • 文章类型: Case Reports
    小儿踝关节损伤是常见的;踝骨phy骨折在儿童中也很常见。但是孤立的腓骨远端骨腓骨远端骨折在临床上很少见。我们描述了一例青少年完全移位的Salter-HarrisII型腓骨远端骨phy骨折的不寻常病例。闭合还原的尝试失败,患者需要切开复位和内固定。局部骨膜和腓骨上支持带从腓骨远端干phy端撕脱,腓骨肌腱在下面露出,但没有明显的半脱位。据我们所知,这种组合的伤害以前没有报道过。
    Pediatric ankle injuries are common; ankle epiphyseal fractures are also common in children. But isolated distal epiphyseal fibular fractures of the distal fibula are clinically rare. We describe one unusual case of an adolescent with a completely displaced Salter-Harris type II distal fibular epiphyseal fracture. The attempt of closed reduction failed, and the patient required open reduction and internal fixation. The localized periosteum and the superior peroneal retinaculum were avulsed from the distal fibular metaphysis, with the peroneal tendons underneath exposed but no obvious subluxation. To the best of our knowledge, this combination of injuries has not been previously reported.
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  • 文章类型: Case Reports
    在以前的报告中,甲状腺功能减退,垂体功能减退,性腺功能减退是SCFE的常见内分泌原因,但这是第一次观察到先天性肾上腺增生。因此,接受长期内分泌治疗的先天性肾上腺增生患者可能面临更高的SCFE风险.
    In previous reports, hypothyroidism, hypopituitrism, and hypogonadism were common endocrine causes of SCFE, but this is the first time that congenital adrenal hyperplasia has been observed. As such, patients who have undergone long-term endocrine treatment for congenital adrenal hyperplasia could potentially be subjected to a higher risk for SCFE.
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  • 文章类型: Journal Article
    背景:儿童胫骨远端骨phy骨折常伴有关节面破坏。随着流离失所的增加,内固定通常使用骨phy螺钉进行,以闭合骨折间隙。尽管有限,高水平的临床证据支持植入物移除,骨phy螺钉通常在骨折愈合后被移除,因为胫骨关节上的接触力可能会增加。这项研究的目的是调查和比较儿童的结果和并发症,这些儿童接受了胫骨远端骨phy骨折的手术治疗,并放置了骨phy螺钉,并且在至少2年的术后随访中保留了植入物。
    方法:来自两个城市三级护理中心的18岁以下儿童接受了胫骨远端Salter-HarrisIII和IV骨折的手术治疗(2013-2020年)。人口统计,术中,术后,并收集射线照相数据。在最后的随访中收集使用足踝能力测量(FAAM)和单一评估数字评估(SANE)问卷的患者报告结果(PRO)。统计分析,包括功率分析,已执行。
    结果:包括52名儿童(30名男性,22名女性),受伤时平均年龄为13.3岁(范围,7.7-16.4年)。35名儿童保留了植入物;17名儿童移除了植入物。所有人都完成了FAAM问卷,平均随访时间为4.4±1.9年,29人完成了SANE问卷,平均随访4.4±1.7年。患者人口统计学无统计学差异,手术变量,或观察到PROs。六个孩子从最初的手术中经历了并发症,包括感染和复杂的区域疼痛综合征,两组间并发症发生率无差异(P=0.08)。此外,未观察到植入物移除导致的并发症.
    结论:与胫骨远端骨phy骨折固定和愈合后取出植入物的儿童相比,保留骨phy植入物的儿童具有相似的功能结局。
    方法:III级回顾性比较研究。
    BACKGROUND: Fractures of the distal tibial epiphysis in children are often accompanied by articular surface disruption. With increased displacement, internal fixation is frequently performed with an epiphyseal screw to close the fracture gap. Despite limited, high-level clinical evidence to support implant removal, epiphyseal screws are commonly removed after fracture healing due to potentially increased contact forces on the tibiotalar joint. The purpose of this study was to investigate and compare outcomes and complications in children that underwent surgical treatment of distal tibial epiphyseal fractures with placement of an epiphyseal screw(s) and had the implant(s) retained versus removed at a minimum of 2-year postoperative follow-up.
    METHODS: Children younger than 18 years from two urban tertiary care centers who underwent operative management of distal tibia Salter-Harris III and IV fractures using epiphyseal screws (2013-2020) were divided into two cohorts: retained epiphyseal screws and implant removed. Demographics, intraoperative, postoperative, and radiographic data were collected. Patient-reported outcomes (PROs) using the Foot and Ankle Ability Measure (FAAM) and Single Assessment Numeric Evaluation (SANE) questionnaires were collected at the final follow-up. Statistical analysis, including power analysis, was performed.
    RESULTS: Fifty-two children were included (30 males, 22 females) with a mean age of 13.3 years at the time of injury (range, 7.7-16.4 years). Thirty-five children retained the implants; seventeen had implants removed. All completed the FAAM questionnaires at a mean follow-up of 4.4 ± 1.9 years, while 29 completed the SANE questionnaire at a mean follow-up of 4.4 ± 1.7 years. No statistically significant difference in patient demographics, surgical variables, or PROs was observed. Six children experienced complications from the initial surgery, including infections and complex regional pain syndrome, with no difference in complication rates between the cohorts ( P =0.08). Furthermore, no complication was observed as a result of implant removal.
    CONCLUSIONS: Children with retained epiphyseal implants have similar functional outcomes as compared with those who had implants removed after distal tibial epiphyseal fracture fixation and union.
    METHODS: Level III-Retrospective comparative study.
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  • 文章类型: Journal Article
    2022年6月9日,张某(男)因涉嫌强制猥亵同学,于案发当时被依法刑事拘留。在审讯过程中,张某自报出生于2006年9月22日;户籍资料记载张某出生于2005年9月22日,男性,汉族,公民身份号码为******20050922****。为正确处理此案,某市公安局委托本鉴定机构对张某本次摄片时(2022年6月10日)的骨龄进行法医学鉴定。.
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  • 文章类型: Journal Article
    对第二次世界大战时期的26个岩骨和掌骨骨的骨p的比较分析显示,DNA产量或STR分型的成功率没有显着差异。岩骨之间DNA保存的意外均等,骨骼遗骸中内源性DNA的著名来源,和掌骨的骨phy,它们是多孔的,容易受到植物学变化的影响,令人惊讶。在这项研究中,我们引入ATR-FTIR光谱作为一种方法来揭示骨分子结构和DNA保存之间的相关性。对具有相同织物学历史的掌骨和岩骨进行采样并准备进行DNA分析。虽然一部分样本用于DNA分析,另一例接受了ATR-FTIR光谱检查.比较了掌骨骨和岩骨骨的归一化光谱和FTIR指数。因为使用的遗骸的纺织历史相对较短和稳定,ATR-FTIR光谱揭示了两种骨骼类型之间的细微结构差异。岩骨表现出更高的矿化,而附生含有更多的有机物。在掌骨骨phy中意外保存DNA可能归因于小梁内软组织残留物的存在。在这里观察到的骨骼分子结构的差异表明,有不同的机制可以在骨骼组织中保存DNA。
    A comparative analysis of 26 petrous bones and epiphyses of metacarpals from the Second World War era revealed no significant differences in DNA yield or success in STR typing. This unexpected parity in DNA preservation between the petrous bone, a renowned source of endogenous DNA in skeletal remains, and the epiphyses of metacarpals, which are porous and susceptible to taphonomic changes, is surprising. In this study, we introduced ATR-FTIR spectroscopy as an approach to unravel the correlation between bone molecular structure and DNA preservation. Metacarpals and petrous bones with same taphonomic history were sampled and prepared for DNA analyses. While one portion of the sample was used for DNA analysis, the other underwent ATR-FTIR spectroscopic examination. The normalized spectra and FTIR indices between the epiphyses of metacarpals and petrous bones were compared. Because the taphonomic history of the remains used is relatively short and stable, the ATR-FTIR spectroscopy unveiled subtle structural differences between the two bone types. Petrous bones exhibited higher mineralization, whereas epiphyses contained more organic matter. The unexpected preservation of DNA in the epiphyses of metacarpals can likely be attributed to the presence of soft tissue remnants within the trabeculae. Here observed differences in the molecular structure of bones indicate there are different mechanisms enabling DNA preservation in skeletal tissues.
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  • 文章类型: Journal Article
    背景和目的:骨龄测定是对不明遗骸进行法医和灾难鉴定的一种有价值的方法,以及医疗和外科手术目的。这项回顾性研究的目的是确定基于骨phy融合阶段的年龄,并调查与性别相关的差异。材料和方法:从约旦南部医院的医学影像中心收集膝盖的X射线,并由两名确定股骨闭合骨epi相的观察者进行检查,胫骨,和腓骨的末端靠近膝盖根据三阶段分类。结果:主要结果表明,与男性相比,女性在股骨下端以及胫骨和腓骨上端显示出较早的骨phy结合(II期)。在男性中,在17-18岁时,可以看到膝关节骨完全愈合的开始(第三阶段),而在女性中,它是在16-17岁的时候看到的。此外,在21-22岁和20-21岁的年龄组中,100%的男性和女性膝关节骨骼显示完全愈合,分别。尽管女性表现出比男性更早的骨phy完全结合的开始和结束,对收集到的数据进行分析显示,在膝关节骨的骨连接的三个阶段,男性和女性之间没有显着的年龄差异。结论:膝关节骨epi骨融合的影像学分析结果是确定实际年龄的有用方法。这项研究支持不同地理位置之间的性别和种族差异。需要大量样本的研究来验证我们的发现。
    Background and Objectives: Bone age determination is a valuable method for forensic and disaster identifications of unknown human remains, as well as for medical and surgical procedural purposes. This retrospective research study aimed to determine the age based on epiphyseal fusion stages and investigate differences related to gender. Materials and Methods: X-rays of the knee were collected from medical imaging centers in hospitals in the south of Jordan and examined by two observers who determined the bone epiphyseal phase of closure for the femur, tibia, and fibula bone ends close to the knee based on a three-stage classification. Results: The main results revealed that females showed earlier epiphyseal union (Stage II) at the lower end of the femur and the upper ends of the tibia and fibula compared to males. In males, the start of complete union (Stage III) at knee bones was seen at the age of 17-18 years, while in females, it was seen at the age of 16-17 years. Additionally, knee bones showed complete union in 100% of males and females in the age groups 21-22 years and 20-21 years, respectively. Although females showed an earlier start and end of epiphyseal complete union than males, analysis of collected data showed no significant age differences between males and females at the three stages of epiphyseal union of the knee bones. Conclusions: Findings of the radiographic analysis of bone epiphyseal fusion at the knee joint are a helpful method for chronological age determination. This study supports the gender and ethnicity variation among different geographical locations. Studies with a high sample number would be needed to validate our findings.
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