背景:需要采取干预措施,以解决服用甲基苯丙胺的人寻求治疗的延误和治疗覆盖率低的问题。
目的:我们的目标是确定基于智能手机的自我管理干预措施是否,“S-Check应用程序”可以增加寻求帮助和改变甲基苯丙胺使用的动机,并确定与应用参与度相关的因素。
方法:这项研究是一项随机的,28天候补名单控制试验。居住在澳大利亚的同意成年人在上个月至少使用过一次甲基苯丙胺,有资格从Android或iOS应用程序商店免费下载该应用程序。那些随机分配到干预组的人可以立即访问S-Check应用程序,对照组在获得访问之前等待了28天,然后所有人都可以进入,直到第56天。实际寻求帮助和寻求帮助的意图通过修改后的实际寻求帮助问卷(MAHSQ)进行评估,修改后的一般帮助寻求问卷,以及修改后的准备统治者改变甲基苯丙胺使用的动机。对MAHSQ的阳性反应比例的χ2比较,修改后的一般帮助寻求问卷,两组之间进行了修改的准备标尺。Logistic回归模型比较了实际求助的几率,寻求帮助的意图,以及在第28天两组之间改变的动机。次要结果是应用程序最常访问的功能,甲基苯丙胺的使用,应用程序的可行性和可接受性,以及S-Check应用程序参与度与参与者人口统计和甲基苯丙胺使用特征之间的关联。
结果:总计,560名参与者下载了应用程序;259名(46.3%)完成了eConsent和基线;84名(32.4%)在第28天提供数据。与对照组相比,即时访问组的参与者在第28天更有可能寻求专业帮助(MAHSQ)(n=15,45.5%vsn=12,23.5%;χ21=4.42,P=.04)。实际寻求帮助的几率没有显着差异,寻求帮助的意图,在主要逻辑回归分析中,或改变两组之间甲基苯丙胺使用的动机,而在辅助分析中,估算的数据集显示,与等候组对照组相比,即时访问组参与者寻求专业帮助的几率存在显著差异(调整后比值比2.64,95%CI1.19-5.83,P=.02).对于未在基线寻求帮助的参与者,应用中的每一分钟都会使第28天寻求专业帮助的可能性增加8%(比率1.08,95%CI1.02-1.22,P=.04).在干预组中,应用参与时间增加10分钟与甲基苯丙胺使用天数减少0.4天相关(回归系数[β]-0.04,P=.02).
结论:对于消耗甲基苯丙胺的澳大利亚成年人,S-Check应用程序是一种可行的低资源自我管理干预措施。研究人员很高,虽然在移动健康干预中很常见,保证对S-Check应用程序进行更大规模的研究。
背景:澳大利亚新西兰临床试验注册中心ACTRN12619000534189;https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=377288&isReview=true。
BACKGROUND: Interventions are required that address delays in treatment-seeking and low treatment coverage among people consuming methamphetamine.
OBJECTIVE: We aim to determine whether a self-administered smartphone-based intervention, the \"S-Check app\" can increase help-seeking and motivation to change methamphetamine use, and determine factors associated with app
engagement.
METHODS: This study is a randomized, 28-day waitlist-controlled trial. Consenting adults residing in Australia who reported using methamphetamine at least once in the last month were eligible to download the app for free from Android or iOS app stores. Those randomized to the intervention group had immediate access to the S-Check app, the control group was wait-listed for 28 days before gaining access, and then all had access until day 56. Actual help-seeking and intention to seek help were assessed by the modified Actual Help Seeking Questionnaire (mAHSQ), modified General Help Seeking Questionnaire, and motivation to change methamphetamine use by the modified readiness ruler. χ2 comparisons of the proportion of positive responses to the mAHSQ, modified General Help Seeking Questionnaire, and modified readiness ruler were conducted between the 2 groups. Logistic regression models compared the odds of actual help-seeking, intention to seek help, and motivation to change at day 28 between the 2 groups. Secondary outcomes were the most commonly accessed features of the app, methamphetamine use, feasibility and acceptability of the app, and associations between S-Check app
engagement and participant demographic and methamphetamine use characteristics.
RESULTS: In total, 560 participants downloaded the app; 259 (46.3%) completed eConsent and baseline; and 84 (32.4%) provided data on day 28. Participants in the immediate access group were more likely to seek professional help (mAHSQ) at day 28 than those in the control group (n=15, 45.5% vs n=12, 23.5%; χ21=4.42, P=.04). There was no significant difference in the odds of actual help-seeking, intention to seek help, or motivation to change methamphetamine use between the 2 groups on the primary logistic regression analyses, while in the ancillary analyses, the imputed data set showed a significant difference in the odds of seeking professional help between participants in the immediate access group compared to the waitlist control group (adjusted odds ratio 2.64, 95% CI 1.19-5.83, P=.02). For participants not seeking help at baseline, each minute in the app increased the likelihood of seeking professional help by day 28 by 8% (ratio 1.08, 95% CI 1.02-1.22, P=.04). Among the intervention group, a 10-minute increase in app
engagement time was associated with a decrease in days of methamphetamine use by 0.4 days (regression coefficient [β] -0.04, P=.02).
CONCLUSIONS: The S-Check app is a feasible low-resource self-administered intervention for adults in Australia who consume methamphetamine. Study attrition was high and, while common in mobile health interventions, warrants larger studies of the S-Check app.
BACKGROUND: Australian New Zealand Clinical Trials Registry ACTRN12619000534189; https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=377288&isReview=true.