功能性消化不良是一种常见的功能性胃肠病,通常难以治疗。心理治疗干预已被提议作为常规治疗的替代或辅助方法。但其疗效尚不清楚.
本系统综述和荟萃分析旨在评估心理治疗干预治疗功能性消化不良的疗效。
对电子数据库进行了全面检索,从开始到2023年3月,用于评估心理治疗干预对功能性消化不良患者的影响的随机对照试验(RCT)。主要结果指标是胃肠道症状,生活质量,抑郁症,和焦虑。使用ReviewManager5.3软件提取和分析数据。使用Cochrane偏差风险工具评估纳入研究的偏差风险。
包含1550例功能性消化不良患者的16个RCT纳入荟萃分析。纳入研究中使用的心理治疗干预措施的类型是认知行为疗法(CBT),催眠疗法,和基于正念的减压(MBSR)。对照组进行常规护理,安慰剂,支持疗法,或者没有治疗。荟萃分析显示,心理治疗干预对减轻胃肠道症状有显著作用,功能性消化不良患者的抑郁和焦虑。然而,与对照组相比,接受心理治疗干预的患者的生活质量评分没有显著改善.
心理治疗干预,比如CBT,催眠疗法,MBSR,可能是功能性消化不良常规治疗的有用辅助手段,因为发现它们可以显着减轻患者的胃肠道症状和焦虑。然而,需要进一步的研究来评估这些干预措施的长期效果和普遍性.
Functional
dyspepsia is a common functional gastrointestinal disorder that is often challenging to treat. Psychotherapeutic interventions have been proposed as an alternative or adjunctive approach to conventional treatments, but their efficacy remains unclear.
This systematic review and meta-analysis aimed to evaluate the efficacy of psychotherapeutic interventions in the treatment of functional
dyspepsia.
A comprehensive search of electronic databases was conducted, from inception to March 2023, for randomized controlled trials (RCTs) that evaluated the effects of psychotherapeutic interventions on patients with functional
dyspepsia. The primary outcome measures were gastrointestinal symptoms, quality of life, depression, and anxiety. Data were extracted and analyzed using Review Manager 5.3 software. The risk of bias of the included studies was assessed using the Cochrane Risk of Bias tool.
Sixteen RCTs comprising 1550 patients with functional
dyspepsia were included in the meta-analysis. The types of psychotherapeutic interventions used in the included studies were cognitive-behavioral therapy (CBT), hypnotherapy, and mindfulness-based stress reduction (MBSR). The control groups were usual care, placebo, supportive therapy, or no treatment. The meta-analysis showed that psychotherapeutic interventions had a significant effect on reducing gastrointestinal symptoms,depression and anxiety in patients with functional dyspepsia. However, no significant improvement was observed in the quality-of-life scores of patients who received psychotherapeutic interventions compared to those in the control group.
Psychotherapeutic interventions, such as CBT, hypnotherapy, and MBSR, could be a useful adjunct to conventional treatments for functional
dyspepsia, as they were found to significantly reduce gastrointestinal symptoms and anxiety in patients. However, further studies are needed to assess the long-term effects and generalizability of these interventions.