deglutition disorders

吞咽障碍
  • 文章类型: Case Reports
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  • 文章类型: Journal Article
    背景:本研究的目的是确定喉部症状的围手术期危险因素,并为接受冠状动脉旁路移植术(CABG)的中国住院患者建立可实施的风险预测模型。
    方法:纳入2020年1月至2022年6月武汉亚洲心脏病医院收治的1476例中国CABG患者,然后分为建模队列和验证队列。单因素分析用于确定喉部症状的危险因素。应用多因素logistic回归建立CABG术后喉症状预测模型。基于受试者工作特性(ROC)曲线下面积和Hosmer-Lemeshow(H-L)检验,对该模型进行了鉴别和校准。分别。
    结果:接受CABG的患者喉部症状的发生率为6.48%。模型中包括四个独立的危险因素,建立的咽部并发症风险计算公式为Logit(P)=-4.525+0.824×女性+2.09×体重指数<18.5Kg/m2+0.793×经食管超声心动图+1.218×重症监护病房插管时间。对于喉部症状,衍生队列的ROC曲线下面积为0.769(95%置信区间[CI]:0.698~0.840),验证队列为0.811(95%CI:0.742~0.879).根据H-L检验,模型组和验证组的P值分别为0.659和0.838.
    结论:本研究开发的预测模型可用于识别接受CABG的喉部症状的高风险患者,并帮助临床医生实施后续治疗。
    BACKGROUND: The aim of this study was to identify perioperative risk factors of laryngeal symptoms and to develop an implementable risk prediction model for Chinese hospitalized patients undergoing coronary artery bypass grafting (CABG).
    METHODS: A total of 1476 Chinese CABG patients admitted to Wuhan Asian Heart Hospital from January 2020 to June 2022 were included and then divided into a modeling cohort and a verification cohort. Univariate analysis was used to identify laryngeal symptoms risk factors, and multivariate logistic regression was applied to construct a prediction model for laryngeal symptoms after CABG. Discrimination and calibration of this model were validated based on the area under the receiver operating characteristic (ROC) curve and the Hosmer-Lemeshow (H-L) test, respectively.
    RESULTS: The incidence of laryngeal symptoms in patients who underwent CABG was 6.48%. Four independent risk factors were included in the model, and the established aryngeal complications risk calculation formula was Logit (P) = -4.525 + 0.824 × female + 2.09 × body mass index < 18.5 Kg/m2 + 0.793 × transesophageal echocardiogram + 1.218 × intensive care unit intubation time. For laryngeal symptoms, the area under the ROC curve was 0.769 in the derivation cohort (95% confidence interval [CI]: 0.698-0.840) and 0.811 in the validation cohort (95% CI: 0.742-0.879). According to the H-L test, the P-values in the modeling group and the verification group were 0.659 and 0.838, respectively.
    CONCLUSIONS: The prediction model developed in this study can be used to identify high-risk patients for laryngealsymptoms undergoing CABG, and help clinicians implement the follow-up treatment.
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  • 文章类型: Journal Article
    颈椎前路手术后的吞咽困难在手术后1年后的发生率为5%至15%,通常归因于机械因素,如咽部增厚和会厌内翻。尽管神经系统检查和肌电图正常,在这些患者中,与拉伸相关的神经变形也仍然存在可能性,并可能导致异常性疼痛,导致吞咽困难和吞咽困难。颈椎前路椎间盘切除术和融合术后吞咽困难的当前治疗选择仅限于局部术中类固醇注射和气管牵引锻炼。在我们的病人身上,舌咽神经阻滞有效地用于控制舌咽异常痛,从而减少吞咽困难和吞咽困难,最终增强口服耐受性。
    Dysphagia after anterior cervical spine surgery has a 5% to 15% incidence beyond 1-year postsurgery, often attributed to mechanical factors such as pharyngeal thickening and epiglottis inversion. Despite normal neurological examination and electromyography, nerve distortion related to stretching also remains a possibility in these patients and may cause allodynia resulting in odynophagia and dysphagia. Current treatment options for dysphagia after anterior cervical discectomy and fusion are limited to local intraoperative steroid injections and tracheal traction exercises. In our patient, a glossopharyngeal nerve block was effectively used to manage the glossopharyngeal allodynia, thereby reducing the odynophagia and dysphagia, ultimately enhancing oral tolerance.
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  • 文章类型: Journal Article
    在研究中与利益相关者进行有意义的接触需要有意识的方法。本文介绍了一个框架的开发,以指导利益相关者作为研究伙伴参与一项务实试验,该试验旨在评估头颈部癌症患者吞咽困难的行为干预措施。我们强调利益相关者参与的核心原则,包括代表所有观点,有意义的参与,尊重与利益相关者的伙伴关系,以及对利益相关者的责任;并描述这些原则是如何在整个大型临床试验过程中实施的,以吸引相关利益相关者的参与。
    Meaningful engagement with stakeholders in research demands intentional approaches. This paper describes the development of a framework to guide stakeholder engagement as research partners in a pragmatic trial proposed to evaluate behavioral interventions for dysphagia in head and neck cancer patients. We highlight the core principles of stakeholder engagement including representation of all perspectives, meaningful participation, respectful partnership with stakeholders, and accountability to stakeholders; and describe how these principles were operationalized to engage relevant stakeholders throughout the course of a large clinical trial.
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  • 文章类型: Journal Article
    这篇立场文件涉及奥地利嗜酸性食管炎网络发布的关于嗜酸性食管炎和食道食物嵌塞的诊断和管理的专家共识,由奥地利胃肠病学和肝病学会(OGGH)赞助的工作组。需要一种标准化的EoE管理方法,建议是根据国际准则和具有里程碑意义的研究提出的。
    This position paper deals with an expert consensus on diagnosis and management of eosinophilic esophagitis and esophageal food impaction issued by the Austrian Eosinophilic Esophagitis Network, a working group under the patronage of the Austrian Society of Gastroenterology and Hepatology (ÖGGH). In need of a standardized approach on the management of EoE, recommendations were made based on international guidelines and landmark studies.
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  • 文章类型: Journal Article
    对小新生儿进行口腔感觉运动干预的现有证据不强。在很大程度上缺乏对病足月新生儿进行干预的证据。研究受到偏见和不一致风险的限制。依赖于单一刺激技术的干预措施的证据似乎只有低至非常低。需要不断的研究。贡献:我们描述了嵌入袋鼠母亲护理(KMC)实践中的五部分新生儿吞咽和母乳喂养干预计划。借鉴口咽生理学,新生儿科,神经发育护理,母乳喂养和KMC科学,该计划是语言治疗师和医生之间合作的产物,和他们的团队。它的实施取决于指导母亲和新生儿护理团队。邀请研究人员确定该计划的结果。
    Available evidence of oral sensorimotor interventions for small neonates is not strong. Evidence of interventions for sick term neonates is largely lacking. Studies are limited by risk of bias and inconsistency. Evidence of interventions relying on a single stimulation technique only appears to be low to very low. Ongoing research is required.Contribution: We describe a five-component neonatal swallowing and breastfeeding intervention programme embedded in the practice of kangaroo mother care (KMC). Drawing on oropharyngeal physiology, neonatology, neurodevelopmental care, breastfeeding- and KMC science, the programme is the product of collaboration between a speech-language therapist and a medical doctor, and their team. Its implementation is dependent on coaching mothers and the neonatal care team. Researchers are invited to determine outcomes of the programme.
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  • 文章类型: Journal Article
    目的:了解成人吞咽困难患者家庭照顾者的认知和体验。
    背景:吞咽困难是一种常见的症状,给护理人员带来很大的负担。有越来越多的研究集中在照顾者和照顾经验。然而,没有进行定性的荟萃综合来探索家庭照顾者的看法和经验.
    方法:定性荟萃人种学。
    方法:在六个电子数据库(PubMed,WebofScience,CINAHL,奥维德,科克伦图书馆,ProQuest)和两个中文数据库(CNKI,万方数据)从成立至2023年2月。使用JoannaBriggs研究所定性评估和审查仪器(JBI-QARI)评估研究质量。元人种学方法用于综合来自定性研究的数据。该研究是根据EQUATOR指南报告的。
    结果:纳入了11项研究,出现了三个主题:(1)情感和感知,(2)变化与挑战(3)适应与应对。
    结论:这篇综述强调了护理人员所面临的挑战和积极应对。研究结果直接指导支持性干预措施的制定和实施,以减轻护理人员的压力并促进适应性应对。
    结论:关注吞咽困难家庭照顾者的需求。家庭护理人员对吞咽困难的严重程度需要评估。护理人员需要知识,支持,和指导减轻他们的负担和发挥作用。
    OBJECTIVE: To understand the perceptions and experiences of family caregivers of adult patients with dysphagia.
    BACKGROUND: Dysphagia is a common symptom and burdens caregivers greatly. There is a growing body of studies concentrating on caregivers and caregiving experiences. However, no qualitative meta-synthesis has been conducted to explore the perceptions and experiences of family caregivers.
    METHODS: A qualitative meta-ethnography.
    METHODS: A search was conducted for relevant articles in six electronic databases (PubMed, Web of Science, CINAHL, Ovid, Cochrane Library, ProQuest) and two Chinese databases (CNKI, Wanfang Data) from inception to February 2023. The Joanna Briggs Institute Qualitative Assessment and Review Instrument (JBI-QARI) was used to evaluate study quality. The meta-ethnographic method was used to synthesize data from qualitative studies. The study was reported according to EQUATOR guidelines.
    RESULTS: Eleven studies were included and three themes emerged: (1) emotion and perception, (2) change and challenge (3) adaption and coping.
    CONCLUSIONS: This review highlighted the challenges and positive coping experienced by caregivers. Findings directly inform the development and implementation of supportive interventions to reduce caregivers\' stress and promote adaptive coping.
    CONCLUSIONS: Pay attention to the needs of family caregivers of dysphagia. Family caregivers\' perceived severity of dysphagia requires assessment. Caregivers need knowledge, support, and guidance to reduce their burden and fulfill their role.
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  • 文章类型: Journal Article
    背景:在重症监护病房(ICU)气管内插管后,拔管后吞咽困难(PED)是一种常见的并发症。PED与不良后果密切相关,包括抽吸,肺炎,营养不良,死亡率上升,和长期住院,导致医疗支出增加。然而,报告的PED发病率在现有文献中差异很大.因此,本综述的主要目的是对接受经口气管插管的ICU患者的PED发生率进行综合评估.
    方法:我们搜索了Embase,PubMed,WebofScience,科克伦图书馆,中国国家知识基础设施(CNKI),万方数据库,中国科学,科技期刊数据库(VIP),和SinoMed数据库从成立到2023年8月。两名评审员独立筛选研究并提取数据。随后,利用StataSE15.0版中的"metaprop"命令,采用随机效应模型进行荟萃统计分析,以确定PED的发生率.此外,我们进行了亚组分析和荟萃回归,以阐明纳入研究的异质性的潜在来源.
    结果:在4144项研究中,本综述包括30项研究。PED的总体合并发生率为36%(95%置信区间[CI]29-44%)。亚组分析揭示了PED的合并发病率,按评估时间分层(≤3小时,4-6小时,≤24h,且≤48h),如下:31.0%(95%CI8.0-59.0%),28%(95%CI22.0-35.0%),41%(95%CI33.0-49.0%),和49.0%(95%CI34.0-63.0%),分别。当样本量为100结论:在接受经口气管插管的ICU患者中,PED的发生率较高。ICU专业人员应提高对PED的认识。同时,对于准确评估PED的发生率,必须就最合适的PED评估时间和评估工具制定指南或达成共识.
    BACKGROUND: Post-extubation dysphagia (PED) emerges as a frequent complication following endotracheal intubation within the intensive care unit (ICU). PED has been strongly linked to adverse outcomes, including aspiration, pneumonia, malnutrition, heightened mortality rates, and prolonged hospitalization, resulting in escalated healthcare expenditures. Nevertheless, the reported incidence of PED varies substantially across the existing body of literature. Therefore, the principal objective of this review was to provide a comprehensive estimate of PED incidence in ICU patients undergoing orotracheal intubation.
    METHODS: We searched Embase, PubMed, Web of Science, Cochrane Library, China National Knowledge Infrastructure (CNKI), Wanfang Database, China Science, Technology Journal Database (VIP), and SinoMed databases from inception to August 2023. Two reviewers independently screened studies and extracted data. Subsequently, a random-effects model was employed for meta-statistical analysis utilizing the \"meta prop\" command within Stata SE version 15.0 to ascertain the incidence of PED. In addition, we performed subgroup analyses and meta-regression to elucidate potential sources of heterogeneity among the included studies.
    RESULTS: Of 4144 studies, 30 studies were included in this review. The overall pooled incidence of PED was 36% (95% confidence interval [CI] 29-44%). Subgroup analyses unveiled that the pooled incidence of PED, stratified by assessment time (≤ 3 h, 4-6 h, ≤ 24 h, and ≤ 48 h), was as follows: 31.0% (95% CI 8.0-59.0%), 28% (95% CI 22.0-35.0%), 41% (95% CI 33.0-49.0%), and 49.0% (95% CI 34.0-63.0%), respectively. When sample size was 100 < N ≤ 300, the PED incidence was more close to the overall PED incidence. Meta-regression analysis highlighted that sample size, assessment time and mean intubation time constituted the source of heterogeneity among the included studies.
    CONCLUSIONS: The incidence of PED was high among ICU patients who underwent orotracheal intubation. ICU professionals should raise awareness about PED. In the meantime, it is important to develop guidelines or consensus on the most appropriate PED assessment time and assessment tools to accurately assess the incidence of PED.
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  • 文章类型: Journal Article
    吞咽困难,一种影响吞咽能力的疾病,在老年人中患病率很高,并可能导致严重的健康并发症。因此,早期发现吞咽困难很重要。这项研究评估了新开发的深度学习模型的有效性,该模型分析了音节分段数据以诊断吞咽困难,以前的研究中没有提到的一个方面。从16例吞咽困难患者和24例对照中收集了日常对话的音频数据。吞咽困难的存在是通过视频透视吞咽研究确定的。使用语音到文本模型将数据分段为音节,并使用卷积神经网络进行分析,以在吞咽困难患者和对照组之间进行二元分类。本研究中提出的模型从两个不同的方面进行了评估。首先,通过音节分段分析,它对吞咽困难的诊断准确率为0.794,敏感性为0.901,特异性为0.687,阳性预测值为0.742,阴性预测值为0.874。其次,在个人层面,它实现了0.900的整体精度和0.953的曲线下面积。这项研究强调了深度学习模式作为早期,非侵入性,以及在日常环境中检测吞咽困难的简单方法。
    Dysphagia, a disorder affecting the ability to swallow, has a high prevalence among the older adults and can lead to serious health complications. Therefore, early detection of dysphagia is important. This study evaluated the effectiveness of a newly developed deep learning model that analyzes syllable-segmented data for diagnosing dysphagia, an aspect not addressed in prior studies. The audio data of daily conversations were collected from 16 patients with dysphagia and 24 controls. The presence of dysphagia was determined by videofluoroscopic swallowing study. The data were segmented into syllables using a speech-to-text model and analyzed with a convolutional neural network to perform binary classification between the dysphagia patients and control group. The proposed model in this study was assessed in two different aspects. Firstly, with syllable-segmented analysis, it demonstrated a diagnostic accuracy of 0.794 for dysphagia, a sensitivity of 0.901, a specificity of 0.687, a positive predictive value of 0.742, and a negative predictive value of 0.874. Secondly, at the individual level, it achieved an overall accuracy of 0.900 and area under the curve of 0.953. This research highlights the potential of deep learning modal as an early, non-invasive, and simple method for detecting dysphagia in everyday environments.
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  • 文章类型: Journal Article
    背景:口咽吞咽困难(OD)难以从口腔到喉咙操纵食物推注。高达70%的老年人发展OD;然而,它在初级保健中得不到管理,导致可避免的住院。
    目的:本行为科学现实主义者综述旨在开发计划理论,以描述干预措施如何促进初级保健医疗保健专业人员(HCP)主动管理OD。
    方法:我们利用利益相关者的专业知识和理论领域框架(TDF),归纳地开发了初始计划理论(IPT)。搜索数据库以识别有关上下文的证据,与积极管理OD和提供可转移学习的比较行为相关的行为机制和结果。IPT经过测试,有证据证实,提炼或反驳,产生最终的方案理论。
    结果:包括36个证据来源。产生了五个最终计划理论,解释了如何促进初级保健HCP主动管理OD:(1)OD教育和培训,(2)有OD体征和症状的检查表,(3)将OD识别纳入现有工作流程,(4)使HCP意识到老年人和护理人员期望他们管理OD;(5)提高对OD不良后果的认识。
    结论:五种计划理论提供了行为机制,通过这些机制,干预措施可以促进初级保健HCP主动管理OD。通过程序理论与TDF的联系,可以选择映射到相关TDF域的行为改变技术(BCT)进行干预。应使用共同设计方法将选定的BCT操作成连贯的干预方案。
    CRD42022320327。
    BACKGROUND: Oropharyngeal dysphagia (OD) is difficulty manipulating a food bolus from the mouth to the throat. Up to 70% of older adults develop OD; however, it is unmanaged in primary care, leading to avoidable hospitalisation.
    OBJECTIVE: This behavioural science realist review aimed to develop programme theories to describe how interventions facilitate primary care healthcare professionals (HCPs) to proactively manage OD.
    METHODS: We developed initial programme theories (IPTs) inductively using the expertise of stakeholders and deductively using the theoretical domains framework (TDF). Databases were searched to identify evidence regarding contexts, behavioural mechanisms and outcomes related to proactive management of OD and comparative behaviours which offer transferrable learning. IPTs were tested with the evidence to confirm, refine or refute, to produce final programme theories.
    RESULTS: 36 sources of evidence were included. Five final programme theories were generated explaining how primary care HCPs can be facilitated to proactively manage OD: (1) OD education and training, (2) checklists with OD signs and symptoms, (3) incorporating OD identification into existing workflow, (4) making HCPs aware that older adults and carers expect them to manage OD and (5) raising awareness of the adverse outcomes of OD.
    CONCLUSIONS: The five programme theories provide the behavioural mechanisms by which an intervention may facilitate primary care HCPs to proactively manage OD. Through the programme theories\' linkage to the TDF, behaviour change techniques (BCTs) mapped to the relevant TDF domain can be selected for an intervention. Operationalisation of selected BCTs into a coherent intervention package should be undertaken using codesign methodology.
    UNASSIGNED: CRD42022320327.
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