■患有慢性疾病的青少年(AYA)通常难以发展药物依从性技能。这项试点试验评估了移动健康教练干预的影响,手机支持(CPS),关于药物依从性。
■这项随机试验中的干预措施是通过电话(CPS-C)进行的CPS,通过文本消息(CPS-T)传递的CPS,或自动短信提醒(ATR)。参与者是患有不同慢性疾病的AYA(即,镰状细胞病,实体器官移植,2型糖尿病),15-20岁(N=34)。我们研究了可行性,可接受性,及各干预措施的初步疗效。
■我们检查了可行性,可接受性,两种CPS干预措施的初步疗效。CPS是可行和可接受的。有证据表明,参与者发现CPS比ATR更有用。在这个试点试验中,接受CPS的参与者报告说,依从性增加相对更强,与分配给ATR的相比。CPS-C的性能略高于CPS-T。
■为AYA提供指导通过手机与疾病自我管理作斗争可能会促进他们获得药物依从性技能。尽管需要更大的研究来证实这项初步研究的结果,电话和短信都是提供人类手机支持的有希望的方式。
■该试验于2020年1月27日在ClinicalTrials.gov(NCT04241627)进行了前瞻性注册。
UNASSIGNED: Adolescents and young adults (AYA) living with chronic medical conditions often struggle to develop medication adherence skills. This pilot trial evaluated the impact of a mobile health coaching intervention, Cell Phone Support (CPS), on medication adherence.
UNASSIGNED: Interventions in this randomized trial were CPS delivered by phone calls (CPS-C), CPS delivered by text messages (CPS-T), or automated text message reminders (ATR). Participants were AYA with different chronic medical conditions (i.e., sickle cell disease, solid organ transplant, type 2 diabetes), aged 15-20 years (N = 34). We examined the feasibility, acceptability, and preliminary efficacy of each intervention.
UNASSIGNED: We examined the feasibility, acceptability, and preliminary efficacy of both CPS interventions. CPS was feasible and acceptable. There was evidence that participants found CPS to be more useful than ATR. In this pilot trial, participants receiving CPS reported relatively stronger increases in adherence, compared to those assigned to ATR. CPS-C slightly outperformed CPS-T.
UNASSIGNED: Providing coaching to AYA struggling with illness self-management via their cell phones may promote their acquisition of medication adherence skills. Although larger studies are needed to confirm the results of this pilot study, phone calls and text messages are both promising modalities for delivering human cell phone support.
UNASSIGNED: This trial was registered prospectively at ClinicalTrials.gov (NCT04241627) on 1/27/2020.