allograft

同种异体移植物
  • 文章类型: Journal Article
    肱骨近端骨折占阑尾骨骼损伤的4%-8%。大多数是稳定的,老年人骨质疏松性骨折的最小移位,是低能量下降的结果。这些患者中的大多数无需手术干预即可恢复足够的肩部功能。大约20%的患者考虑手术,因为他们需要改善肩关节功能以进行日常生活活动,或者因为他们的骨折严重畸形和需要恢复功能对齐,长度,并在活动中旋转,个人要求更高。然而,由于骨质量差和肩袖的移位力,这些骨折的固定可能会带来挑战。在3部分和4部分骨折中尤其如此。这些因素导致早期尝试进行骨合成时看到的高失败率。在过去的20年里,锁定钢板技术是治疗这些复杂骨折的一项创新。尽管扭转强度和刚度有所改善,锁定钢板技术的结局研究显示结果不明确,并发症发生率高达20%-30%,翻修率为10%.具体来说,这些并发症包括血管坏死,内翻塌陷,关节内螺钉穿刺,术后僵硬。当弱骨质疏松性骨在植入物周围失效时,发生内翻塌陷。反过来,引入腓骨支柱骨膜内增强术,以提供额外的支持,并降低移位的骨折伴内翻冠状畸形和严重的干phy端骨质流失的植入物失败率。尽管临床上成功且生物力学优于仅钢板结构,一些担忧仍然存在。反过来,我们介绍了一种新颖的技术,可以创建单个松质骨股骨头同种异体移植支柱或“法式炸薯条”,该技术为肱骨头提供了结构支撑,但没有皮质腓骨支柱的潜在问题。
    Fractures of the proximal humerus account for 4%-8% of injuries to the appendicular skeleton. Most are stable, minimally displaced osteoporotic fractures in the elderly, and are the result of low-energy falls. A large majority of these patients regain adequate shoulder function without operative intervention. Surgery is considered in approximately 20% of patients because they require improved shoulder function for their activities of daily living or because of the significant deformity of their fracture and the need to restore functional alignment, length, and rotation in active, higher demand individuals. However, fixation of these fractures can pose a challenge due to poor bone quality and displacing forces of the rotator cuff. This is especially true in 3-part and 4-part fractures. These factors lead to the high failure rates seen with early attempts at osteosynthesis. In the last 2 decades, locking plate technology has been an innovation in treating these complex fractures. Despite the improvements in torsional strength and rigidity, outcome studies on locking plate technology demonstrate equivocal results with complication rates as high as 20%-30% and a revision rate of 10%. Specifically, these complications include avascular necrosis, varus collapse, intra-articular screw penetration, and postoperative stiffness. Varus collapse occurs when the weak osteoporotic bone fails around the implant. In turn, fibular strut endosteal augmentation was introduced to provide additional support and decrease implant failure rates in displaced fractures with varus coronal malalignment and significant metaphyseal bone loss. Although clinically successful and biomechanically superior to plate-only constructs, a few concerns remain. In turn, we introduce a novel technique of creating individual cancellous femoral head allograft struts or \"French fries\" that provides structural support for the humeral head but does not have the potential problems of a cortical fibular strut.
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  • 文章类型: Journal Article
    选择合适的移植物进行前交叉韧带(ACL)重建需要考虑患者的偏好,目标,年龄,和身体需求以及每种移植选择的风险和收益。
    确定患者中最受欢迎的ACL重建移植物以及影响其决定的最重要因素。
    横断面研究;证据水平,3.
    在2022年10月至2023年4月期间接受ACL重建的患者在与外科医生交谈之前(非咨询组)或之后(咨询组)完成了一项调查,谁提供了同种异体移植物和以下自体移植物的利弊的循证描述:骨-髌腱-骨(BPTB),腿筋肌腱(HT),和股四头肌腱(QT)。患者特征,移植选择,影响他们移植选择的信息,收集并比较两组之间的外科医生推荐。
    在纳入的100名患者中,59.0%为男性,平均年龄28.3±10.4岁。最受欢迎的移植物是BPTB(56.0%),其次是QT(29.0%),HT(8.0%),和同种异体移植(7.0%)。咨询组之间的移植物选择没有显着差异(n=60;BPTB,46.7%;QT,38.3%;HT,8.3%;同种异体移植,6.7%)和非咨询组(n=40;BPTB,70.0%;QT,15.0%;HT,7.5%;同种异体移植,7.5%)(P=.0757)。在咨询小组中,81.7%的患者选择了外科医生推荐给他们的移植物。选择移植物的前2个原因是专业运动员的使用率和失败率,而前2名ACL手术的关注点是恢复到他们所需的运动水平和移植物失败的风险。在访问前研究ACL移植选项的93名患者中,最受欢迎的信息来源是某种形式的媒体(72.0%[67/93])。
    研究结果强调了患者选择移植物时患者偏好和外科医生推荐的重要性,并强调在研究移植物选择时需要了解患者可用的信息源。
    UNASSIGNED: Selecting an appropriate graft for anterior cruciate ligament (ACL) reconstruction requires consideration of a patient\'s preferences, goals, age, and physical demands alongside the risks and benefits of each graft choice.
    UNASSIGNED: To determine the most popular ACL reconstruction grafts among patients and the most important factors influencing their decisions.
    UNASSIGNED: Cross-sectional study; Level of evidence, 3.
    UNASSIGNED: Patients undergoing ACL reconstruction between October 2022 and April 2023 completed a survey either before (nonconsult group) or after (consult group) speaking with their surgeon, who provided an evidence-based description of the pros and cons of an allograft and the following autografts: bone-patellar tendon-bone (BPTB), hamstring tendon (HT), and quadriceps tendon (QT). Patient characteristics, graft choice, information influencing their graft choice, and surgeon recommendation were collected and compared between the groups.
    UNASSIGNED: Among the 100 included patients, 59.0% were male, and the mean age was 28.3 ± 10.4 years. The most popular grafts were the BPTB (56.0%), followed by the QT (29.0%), HT (8.0%), and allograft (7.0%). No significant difference was observed in the graft selection between the consult group (n = 60; BPTB, 46.7%; QT, 38.3%; HT, 8.3%; allograft, 6.7%) and nonconsult group (n = 40; BPTB, 70.0%; QT, 15.0%; HT, 7.5%; allograft, 7.5%) (P = .0757). In the consult group, 81.7% of patients selected the graft recommended to them by their surgeon. The top 2 graft selection reasons were usage in professional athletes and failure rates, while the top 2 ACL surgery concerns were returning to their desired level of athletics and graft failure risk. Among the 93 patients who researched their ACL graft options before their visit, the most popular information source was some form of media (72.0% [67/93]).
    UNASSIGNED: The study findings underscore the importance of patient preference and surgeon recommendation in a patient\'s graft selection and highlight the need to be cognizant of the information sources available to patients when researching their graft options.
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  • 文章类型: Journal Article
    刚度的变化,固定方法,不同移植类型和前交叉韧带缝合修复(ACLSR)的前交叉韧带重建(ACLR)后的供体部位发病率可导致动态膝关节松弛的差异,并因此导致创伤后骨关节炎(PTOA)发展的差异。
    比较用于原发性ACLR的不同移植物类型之间以及原发性ACLR和ACLSR之间的PTOA发生率。据推测,PTOA的发生率在具有不同自体移植物和同种异体移植物的ACLR之间以及ACLR和ACLSR之间会有所不同。
    系统评价;证据水平,1.
    进行了文献搜索,以确定所有随机对照试验(RCT),比较了不同类型的移植物-绳肌腱(HT)自体移植物之间ACLR后PTOA的影像学证据,骨-髌腱-骨(BPTB)自体移植,股四头肌腱自体移植,和同种异体移植-以及ACLR和ACLSR之间。最少随访2年。使用改良的Coleman方法评分评估研究质量。进行荟萃分析以确定不同移植物类型之间以及ACLR和ACLSR之间的PTOA发生率是否存在差异。
    11项随机对照试验纳入荟萃分析-HT:440例患者(平均随访,9.7年);BPTB:307例患者(平均随访,11.8年);同种异体移植:246例患者(平均随访,5年);ACLSR,22例(5年)。未纳入报告股四头肌腱ACLR后发生率的研究。研究质量从70到88。荟萃分析表明,用于ACLR的移植物类型之间以及ACLR和ACLSR之间的PTOA发生率没有显着差异(风险比:HTvsBPTB,1.05;HT与同种异体移植物,0.81;BPTB与同种异体移植物,0.82;HT与ACLSR,不可估计的[全部P>.05])。在每种移植物类型的所有研究中,患有PTOA的患者的合并数量表明,接受BPTB自体移植物的ACLR患者的PTOA百分比最高(HT,23.4%;BPTB,29.6%;同种异体移植,8.1%;ACLSR,0%)。然而,排除随访<5年的研究,对于接受HT自体移植和BPTB自体移植的患者,结果相似.
    这项荟萃分析报告,用于ACLR的移植物类型之间以及ACLR和ACLSR之间的PTOA发生率没有差异。需要更多的研究才能得出可靠的结论,即哪种技术与ACL手术后的PTOA发生率最低有关。
    UNASSIGNED: Variation in stiffness, fixation methods, and donor-site morbidity after anterior cruciate ligament reconstruction (ACLR) with different graft types and with anterior cruciate ligament suture repair (ACLSR) can lead to differences in dynamic knee laxity and consequent differences in posttraumatic osteoarthritis (PTOA) development.
    UNASSIGNED: To compare the incidence of PTOA between different graft types used for primary ACLR and between primary ACLR and ACLSR. It was hypothesized that the incidence of PTOA would vary between ACLR with different autografts and allografts and between ACLR and ACLSR.
    UNASSIGNED: Systematic review; Level of evidence, 1.
    UNASSIGNED: A search of the literature was performed to identify all randomized controlled trials (RCTs) comparing radiographic evidence of PTOA after ACLR between different graft types-hamstring tendon (HT) autograft, bone-patellar tendon-bone (BPTB) autograft, quadriceps tendon autograft, and allograft-and between ACLR and ACLSR. The minimum follow-up was 2 years. Study quality was assessed using the modified Coleman Methodology Score. A meta-analysis was performed to determine whether there was a difference in the incidence of PTOA between the different graft types and between ACLR and ACLSR.
    UNASSIGNED: Eleven randomized controlled trials were included in the meta-analysis-HT: 440 patients (mean follow-up, 9.7 years); BPTB: 307 patients (mean follow-up, 11.8 years); allograft: 246 patients (mean follow-up, 5 years); ACLSR, 22 patients (5 years). No study reporting the incidence after ACLR with quadriceps tendon was included. The study quality ranged from 70 to 88. The meta-analysis indicated no significant difference in the incidence of PTOA between graft types used for ACLR and between ACLR and ACLSR (risk ratios: HT vs BPTB, 1.05; HT vs allograft, 0.81; BPTB vs allograft, 0.82; HT vs ACLSR, not estimable [P > .05 for all]). The combined number of patients with PTOA in all studies per graft type showed that patients who underwent ACLR with a BPTB autograft had the highest percentage of PTOA (HT, 23.4%; BPTB, 29.6%; allograft, 8.1%; ACLSR, 0%). However, excluding studies with a follow-up <5 years resulted in similar outcomes for patients with an HT autograft and a BPTB autograft.
    UNASSIGNED: This meta-analysis reported no difference in the incidence of PTOA between graft types used for ACLR and between ACLR and ACLSR. More research is necessary to make a reliable conclusion about which technique is associated with the lowest incidence of PTOA after ACL surgery.
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  • 文章类型: Case Reports
    经皮肾镜取石术是一种微创手术,用于设置复杂的结石负担。在其用途中,PCNL可用于治疗同种异体肾移植结石。此病例提出了独特的挑战,并罕见地使用了PCNL,其中涉及切除了2.6厘米的结石,该结石在43岁的男性中出现,患有双重肾脏同种异体移植物。同种异体移植物的独特位置提出了挑战,这些挑战通过平稳的术后过程和没有残留的结石负担来成功导航。文献中很少报道使用PCNL治疗双同种异体肾移植结石。
    Percutaneous Nephrolithotomy is a minimally-invasive procedure used in the setting of complex stone burden. Among its uses, PCNL can be employed to treated renal allograft calculi. This case presented a unique challenge and a rare usage of PCNL that involved removal of a 2.6 cm stone that presented in a 43-year-old male with dual renal allografts. The unique location of the allograft presented challenges that were navigated successfully with an uneventful postoperative course and no residual stone burden. The utilization of PCNL to treat calculi in dual renal allografts has been minimally reported in the literature.
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  • 文章类型: Journal Article
    在原发性前交叉韧带(ACL)重建(ACLR)中,同种异体肌腱被认为具有较高的ACL移植失败率。历史系列可能会因移植物处理方法而产生偏差,这些方法会降低供体肌腱的生物力学特性,例如辐照。超临界二氧化碳(SCCO2)是一种在生理温度下对生物材料进行最终灭菌而无需辐照的有效方法,但迄今为止尚未报道SCCO2处理的同种异体肌腱移植物用于原发性ACLR。
    使用SCCO2同种异体移植物的ACLR将导致可接受的故障率,主观膝关节评分,术后2年进行临床评估。
    案例系列;证据级别,4.
    患者接受了经最终灭菌的SCCO2处理的人gracilis的初级ACLR,长腓骨,半腱肌,胫骨前肌,和胫骨后肌腱同种异体移植。收集患者的人口统计数据,随着肌腱供体的年龄和性别。术后1年,收集主观国际膝关节文献委员会(IKDC)和ACL-受伤后恢复运动(ACL-RSI)评分,以及临床评估。术后2年,重复IKDC和ACL-RSI评分,并恢复运动,并记录了进一步的膝盖受伤。
    总共144名中等年龄为26(IQR14)岁的患者组成了研究组。患者主要为男性(58%)。随访损失率为8%(n=12)。同种异体肌腱供体的平均年龄为37岁(17-58岁),大多数是男性(83%)。平均同种异体移植物直径为8.9±1.0mm。在2年,ACL移植失败发生率为5%(n=7)。所有移植失败的患者年龄≤25岁(P=.007)。供体年龄(≤40岁或>40岁)和供体性别均与移植失败无关(P>.05)。IKDC主观评分中位数为95分,ACL-RSI评分中位数为75分。术后前2年内未对脓毒症进行修订。
    SCCO2处理同种异体肌腱在连续一系列原发性ACLR患者术后24个月显示出令人满意的临床和患者报告结果。与已发表的腿筋肌腱自体移植和新鲜冷冻的未经辐照的同种异体移植系列报道相比,ACL移植失败率和主观膝关节评分相似。
    UNASSIGNED: Allograft tendons are perceived to have a high ACL graft failure rate in primary anterior cruciate ligament (ACL) reconstruction (ACLR). Historical series may be biased by graft processing methods that degrade the biomechanical properties of donor tendons such as irradiation. Supercritical carbon dioxide (SCCO2) is a validated method of terminally sterilizing biomaterials at physiological temperatures without irradiation, but in vivo use of SCCO2-processed tendon allografts for primary ACLR has not been reported to date.
    UNASSIGNED: ACLR with SCCO2 allografts would result in acceptable failure rates, subjective knee scores, and clinical evaluation at 2 years postoperatively.
    UNASSIGNED: Case series; Level of evidence, 4.
    UNASSIGNED: Patients underwent primary ACLR with terminally sterilized SCCO2-processed human gracilis, peroneus longus, semitendinosus, tibialis anterior, and tibialis posterior tendon allografts. Patient demographics were collected, along with tendon donor age and sex. At 1 year postoperatively, subjective International Knee Documentation Committee (IKDC) and ACL-Return to Sport After Injury (ACL-RSI) scores were collected, as well as clinical evaluation. At 2 years postoperatively, the IKDC and ACL-RSI scores were repeated, and return to sports and further knee injuries were recorded.
    UNASSIGNED: A total of 144 patients with a medianage of 26 (IQR 14) years formed the study group. Patients were predominately male (58%). The loss to follow-up rate was 8% (n = 12). The mean age of allograft tendon donors was 37 (range 17-58) years, and the majority were male (83%). The mean allograft diameter was 8.9 ± 1.0 mm. At 2 years, ACL graft failureoccurred in 5% (n = 7). All graft failureswere in patients aged ≤25 years (P = .007). Neither donor age (≤40 or >40 years) nor donor sex was associated with graft failure (P > .05). The median IKDC subjective score was 95 and ACL-RSI score was 75. There were no revisions for sepsis within the first 2 years postoperatively.
    UNASSIGNED: SCCO2 processing of allograft tendons demonstrated satisfactory clinical and patient-reported outcomes at 24 months postoperatively in a consecutive series of patients with primary ACLR, with similar ACL graft failure rates and subjective knee scores compared with those reported in published series of hamstring tendon autograft and fresh frozen nonirradiated allograft.
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  • 文章类型: Journal Article
    目的:唇腭裂是全球最常见的颅面畸形。牙槽突裂用植骨治疗,4至7岁之间的混合牙列。这是一个重要的步骤,因为它提供了高质量的颌骨,并在裂口侧提供了对嘴唇和翼软骨的更好的支撑。骨自体移植与髂骨收获仍然是最常用的技术,但这并非没有风险。因此,已经描述了同种异体移植技术来降低这种发病率(疼痛,感染风险,出血性风险,骨折风险)。这项研究的目的是评估,同种异体移植一年后,牙槽突裂同种异体骨移植的有效性和巩固性。
    方法:在里昂妇女母婴医院的小儿颅颌面外科进行了一项回顾性研究,法国。
    方法:本系列包括22例患者或25例牙槽突裂骨移植,包括16个男孩和6个女孩,平均年龄为6.1岁。
    方法:通过在术前和术后锥形束计算机断层扫描中评估骨移植物的体积与初始空间的体积之间的比率来量化残余同种异体骨。
    结果:1年同种异体骨残植率为58.5%(±22.3)。
    结论:采用同种异体骨移植的牙槽突裂骨移植可替代自体骨移植以降低供区发病率。
    OBJECTIVE: Cleft lip and palate are the most common craniofacial malformations worldwide. The alveolar cleft is treated with a bone graft, between 4 and 7 years of age in mixed dentition. This is an important step because it provides good quality jawbone and a better support of the lip and the alar cartilage on the side of the cleft. Bone autografting with iliac harvesting remains the most commonly used technique, but it is not without risks. Allograft techniques have therefore been described to reduce this morbidity (pain, infectious risk, hemorrhagic risk, fracture risk). The aim of this study was to evaluate, one year after allografting, the efficiency and consolidation of the bone allograft in the alveolar cleft.
    METHODS: A retrospective study was conducted in the department of pediatric craniomaxillofacial surgery in the Woman-Mother-Child Hospital in Lyon, France.
    METHODS: This series includes 22 patients or 25 alveolar cleft bone grafts, including 16 boys and 6 girls, with an average age of 6.1 years.
    METHODS: Quantify the residual bone allograft by evaluating the ratio between the volume of the bone graft and the volume of the initial space on pre- and post-operative cone beam computed tomography.
    RESULTS: The residual bone allograft percentage at 1 year was 58.5% (± 22.3).
    CONCLUSIONS: Alveolar cleft bone graft with bone allograft is an alternative to iliac autografting to reduce donor site morbidity.
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  • 文章类型: Journal Article
    背景:牙齿周围的骨缺损影响了很大一部分人群。现有牙齿区域的骨再生与无牙区域的骨再生完全不同。迄今为止,尚未开发出在保留牙齿的区域进行三维(3D)骨骼重建的方法。
    目的:本研究旨在放射学上评估使用定制的同种异体骨块在保留的牙列中进行3D下颌骨重建的新方法的结果,并进行6个月的随访。
    方法:使用锥形束计算机断层扫描(CBCT)扫描在32例患者(192颗牙齿)的重建前和重建后6个月进行影像学评估。重建使用了先前使用CAD/CAM技术计划和准备的骨块。
    结果:在大多数情况下,观察到的牙槽骨尺寸的变化非常显着(p<0.001)。越靠近牙根尖,矢状尺寸的骨生长越低(在测量高度中检查的每颗牙齿的平均值的平均值):CEJ2:2.9mm,½CEJ2:2.7毫米,?CEJ2:1.9毫米,和API:1.4毫米。在牙齿43(9.9毫米)上观察到垂直尺寸的最大骨骼生长,其次是32(9.8毫米),33(8.5mm),31(8.4mm),42(8毫米),和41(7毫米)。牙齿越靠近中线,骨骼前庭开裂的减少程度越大(中切牙平均为-3.8mm和-3.4mm;侧切牙平均为-2.8mm和-2.6mm;犬齿平均为-2.6mm和-2.5mm)。
    结论:结果证明,正畸治疗患者可以预防骨开裂,提高覆盖衰退的能力和有效性,改善面部下部的形态。
    BACKGROUND: Bone defects around the teeth affect a large portion of the population. Bone regeneration in the area of existing teeth is completely different from that in an edentulous area. To date, no method has been developed for three-dimensional (3D) bone reconstruction in regions with preserved teeth.
    OBJECTIVE: This study aimed to radiologically evaluate the results of the new method of 3D mandibular bone reconstruction in preserved dentition using a custom-made allogeneic bone block with a 6-month follow-up.
    METHODS: Alveolar ridge dimensions were radiographically assessed before and 6 months after reconstruction using cone beam computed tomography (CBCT) scans in 32 patients (192 teeth). Reconstruction used a bone block that had been previously planned and prepared using CAD/CAM technology.
    RESULTS: The observed changes in alveolar bone dimensions were highly significant in most cases (p < 0.001). The closer to the tooth root apex, the lower the bone growth in the sagittal dimension (average of the mean values for each tooth examined in the measured heights): CEJ2: 2.9 mm, ½ CEJ2: 2.7 mm, ¼ CEJ2: 1.9 mm, and API: 1.4 mm. The maximum bone growth in the vertical dimension was observed on tooth 43 (9.9 mm), followed by 32 (9.8 mm), 33 (8.5 mm), 31 (8.4 mm), 42 (8 mm), and 41 (7 mm). The degree of decrease in vestibular dehiscence of the bone was greater the closer the tooth was to the midline (average of -3.8 mm and -3.4 mm for the central incisors; average of -2.8 mm and -2.6 mm for the lateral incisors; average of -2.6 mm and -2.5 mm for the canines).
    CONCLUSIONS: The results prove that it is possible to prevent bone dehiscence in patients undergoing orthodontic treatment, increasing the ability and effectiveness of covering recessions and improving the morphology of the lower part of the face.
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  • 文章类型: Journal Article
    背景:由于骨骼质量差以及垂直骨高度的损失,上颌骨后部对植入物插入提出了挑战。当需要增加几毫米的高度时,建议采用间接的经齿窦提升技术。这项研究旨在评估窦膜球囊技术与Densahburs在同时放置植入物的情况下进行经颌骨上颌窦提升的临床和影像学结果。
    方法:这项随机临床试验是对22例患者进行的,这些患者接受了32次牙种植体,用于在上颌窦抬升后替换错过的上颌后牙。将患者随机分为两组。第1组,患者使用窦膜球囊技术同时进行植入植入,同时进行窦底抬高。第2组,患者使用Densahburs同时进行植入物植入,同时进行了窦底抬高。立即定期使用锥形束计算机断层扫描(CBCT)对患者进行临床和影像学评估,术后6个月和12个月。对所有临床和影像学参数进行统计分析。
    结果:所有牙种植体均成功,随访12个月。关于植入物的主要稳定性,有统计学上的显著差异,有利于Densah组(P=0.004),6个月后差异无统计学意义(P=0.07)。射线照相,球囊组术后即刻垂直骨高度有统计学意义(P<0.0001),6个月后垂直骨高度显著降低(P<0.0001)。Densah组骨密度显著增加(P≤0.05)。
    结论:两种技术均显示出成功的临床和影像学结果。窦膜球囊组表现出更好的术后即刻垂直骨增益,而DensahBurs具有较高的种植体初级稳定性和骨密度。
    背景:本研究已在Clinical-Trials.govPRS(https://register。
    结果:gov),ID号为NCT05922592,日期为2023年6月28日。
    BACKGROUND: The posterior maxilla presents challenges for implant insertion because of the poor bone quality as well as the loss of vertical bone height. Indirect transcrestal sinus lift techniques are advised when a few millimeters of additional height are needed. This study aimed to evaluate the clinical and radiographic outcomes of antral membrane balloon technique versus Densah burs for transcrestal maxillary sinus lifting with simultaneous implant placement.
    METHODS: This randomized clinical trial was conducted on 22 patients received 32 dental implants for replacement of missed maxillary posterior teeth after crestal maxillary sinus lifting. The patients were randomly divided into two groups. Group 1, patients underwent crestal sinus floor elevation with simultaneous implant placement using antral membrane balloon technique. Group 2, patients underwent crestal sinus floor elevation with simultaneous implant placement using Densah burs. Patients were evaluated clinically and radiographically using cone beam computed tomography (CBCT) at regular time intervals immediately, 6 months and 12 months after surgery. All clinical and radiographic parameters were statistically analyzed.
    RESULTS: All dental implants were successful for 12 months of follow up. Regarding implant primary stability, there was a statistical significant difference between the study groups in favor of Densah group (P = 0.004), while there was no significant difference after 6 months (P = 0.07). Radiographically, balloon group showed a statistically significant immediate postoperative vertical bone height (P < 0.0001), and significant reduction in vertical bone height after 6 months (P < 0.0001). Densah group showed significant increase in bone density (P ≤ 0.05).
    CONCLUSIONS: Both techniques demonstrated successful clinical and radiographic outcomes for crestal sinus lift. The antral membrane balloon group demonstrated better immediate postoperative vertical bone gain, while Densah burs had higher implant primary stability and bone density.
    BACKGROUND: This study was registered in Clinical-Trials.gov PRS ( https://register.
    RESULTS: gov ) under identification number NCT05922592 on 28/06/2023.
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  • 文章类型: Case Reports
    这项研究介绍了一名40岁的男性患者在肾移植后的情况。CT扫描显示下腹部和骨盆有一个大肿块,右髂外动脉的分支与生长相交。经过全面检查,研究表明,肿块来自移植的肾脏,并进行了根治性肾切除术(包括肿块)。我们记录了一例发生在移植肾中的非典型血管平滑肌脂肪瘤(AAM)。本文报道了该病例的研究,并对其临床表现进行了简要的文献综述,AAM的诊断和治疗。
    This study presents the case of a 40-year-old male patient after renal transplantation. The CT scan revealed a large mass in the lower abdomen and pelvis, with a branch of the right external iliac artery intersecting the growth. After a comprehensive examination, it was shown that the mass originated from the transplanted kidney, and a radical nephrectomy (including the mass) was performed. We document a case of atypical angiomyolipoma (AAM) occurring in a transplanted kidney. This article reports the case study and a brief literature review of the clinical presentation, diagnosis and treatment of AAM.
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  • 文章类型: Journal Article
    背景:隆鼻是世界五大美学手术之一。据报道,膨胀聚四氟乙烯(ePTFE)是增加鼻背和鼻尖的合理选择。然而,其在鼻尖扩张中的应用存在一些争论。这项研究提出了一种使用ePTFE移植物与人无细胞真皮基质(HADM)相结合的技术,以重建由先前的鼻成形术引起的畸形鼻子。
    方法:从2022年8月至2022年9月来医院进行鼻畸形手术翻修的50例女性患者。ePTFE用于重建鼻背,tip,和小柱支柱。HADM移植物用于加固重建的框架。对患者的美学和功能结果进行了至少12个月的评估。
    结果:术后,鼻背长度从38.9±1.32mm增加到43.4±1.22mm;鼻尖的突起也从19.8±1.16上升到23.9±1.05mm。38名患者(76%)报告说,他们的呼吸和气味与术前相比有所改善。没有病例有植入反应,挤压,或者扭曲小柱支柱。大多数患者(84%)对手术结果感到满意。三名患者(6%)在鼻尖发红。10例患者(20%)的鼻尖在术后3个月内变硬。术后3个月,有6%的患者发生感染,2%的患者尖端软组织不对称。
    结论:该技术为患者带来了令人满意的美学和功能效果,术后12个月未观察到挤压或排斥。感染是一种突出的并发症,应予以考虑并严格监测。
    方法:本期刊要求作者为每篇文章分配一定程度的证据。对于这些循证医学评级的完整描述,请参阅目录或在线作者说明www。springer.com/00266.
    BACKGROUND: Augmentation rhinoplasty is one of five aesthetic surgeries in the world. Expanded polytetrafluoroethylene (ePTFE) has been reported as a rational choice to augment the nasal dorsum and tip. However, its application for nasal tip augmentation has some debates. This study presented a technique using ePTFE grafts combined with human acellular dermis matrix (HADM) to reconstruct a deformed nose caused by previous rhinoplasties.
    METHODS: 50 female patients who came to the hospital from 08/2022 to 09/2022 for surgical revision of their nasal deformity. ePTFE was applied to reconstruct the nasal dorsum, tip, and columella strut. HADM grafts were utilized to reinforce the reconstructed framework. Patients were evaluated for at least 12 months for both aesthetic and functional results.
    RESULTS: Postoperatively, the nasal dorsal length increased from 38.9 ± 1.32 to 43.4 ± 1.22 mm; while, the projection of the nasal tip also raised from 19.8 ± 1.16 to 23.9 ± 1.05 mm. 38 patients (76%) reported that their breathing and smelling were improved compared to preoperatively. No cases had implant reactions, extrusion, or warping columella strut. Most of the patients (84%) were satisfied with the surgical outcomes. Three patients (6%) had redness at the nasal tip. The nasal tip of ten patients (20%) was hardened for 3 months postoperatively. There were 6% of patients who developed an infection and 2% of patients had asymmetric soft tissues of the tip 3 postoperative months.
    CONCLUSIONS: This technique brought satisfactory aesthetic and functional results to patients, with no extrusion or rejection observed 12 months postoperatively. Infection was a prominent complication that should be considered and strictly monitored.
    METHODS: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to Table of Contents or the online Instructions to Authors www.springer.com/00266 .
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