Postoperative complication

术后并发症
  • 文章类型: Journal Article
    没有关于胸外科手术后应选择的胸管数量和尺寸的标准指南。本研究旨在评估采用双尾纤导管(BPCs)引流策略对通过单孔电视辅助胸外科(VATS)进行肺叶切除术的患者的影响。
    对2021年8月至2022年8月在大连理工大学肿瘤医院胸外科接受单孔肺叶切除术的患者进行了回顾性研究。根据所采取的引流策略将患者分为以下两组:(I)传统胸管(TCT)组;(II)BPC组。测量的结果包括术后并发症,通过Clavien-Dindo方法测量,术后患者疼痛视觉模拟评分(VAS)。
    总共,868例患者在研究期间接受了肺切除术,排除后,回顾了470例接受单行肺叶切除术的患者的资料(TCT组235例,和BPC组中的235)。两组基线资料比较差异无统计学意义(P>0.05)。术后并发症发生率(7.7%vs.19.1%)和术后7-24小时的VAS疼痛评分(3.3±1.0vs.3.7±1.5)和25-48小时(3.1±0.8vs.BPC组的3.6±1.5)明显低于TCT组(均P<0.001)。此外,术后住院时间(4.6±1.5vs.5.4±4.5天)和残余肺的塌陷率(19.2%±9.1%vs.BPC组20.9%±9.6%)优于TCT组(P<0.05)。单变量和多变量分析的结果表明,TCT引流策略是减少术后并发症的独立危险因素。手术后7-24和25-48小时,中度或重度疼痛评分降低。
    我们的BPCs引流策略降低了单管胸腔镜肺叶切除术患者术后并发症的发生率,减轻了术后疼痛,是安全可行的。
    UNASSIGNED: There are no standard guidelines regarding the number and size of chest tubes that should be selected after thoracic surgery. This study aimed to evaluate the effects of adopting a drainage strategy with bi-pigtail catheters (BPCs) on patients undergoing lobectomy by uniportal video-assisted thoracic surgery (VATS).
    UNASSIGNED: A retrospective study was performed of patients undergoing uniportal lobectomy at the Department of Thoracic Surgery of the Cancer Hospital of Dalian University of Technology between August 2021 and August 2022. The patients were divided into the following two groups according to the drainage strategy adopted: (I) a traditional chest tube (TCT) group; and (II) a BPC group. The outcomes measured included postoperative complications, as measured by the Clavien-Dindo method, and the visual analogue scale (VAS) pain scores of the patients after surgery.
    UNASSIGNED: In total, 868 patients underwent lung resection during the study period, after exclusion, the data of 470 patients who underwent uniport lobectomy were reviewed (235 in the TCT group, and 235 in the BPC group). There were no statistically significant differences between the two groups in terms of baseline data (P>0.05). The incidence of postoperative complications (7.7% vs. 19.1%) and postoperative VAS pain scores at 7-24 hours (3.3±1.0 vs. 3.7±1.5) and 25-48 hours (3.1±0.8 vs. 3.6±1.5) were significantly lower in the BPC group than the TCT group (all P<0.001). Additionally, the postoperative length of stay (4.6±1.5 vs. 5.4±4.5 days) and the collapse rate of the residual lung (19.2%±9.1% vs. 20.9%±9.6%) of the BPC group were better than those of the TCT group (P<0.05). The results of univariable and multivariable analyses showed that a drainage strategy with a TCT was an independent risk factor for decreased postoperative complications, and reduced moderate or severe pain scores at 7-24 and 25-48 hours after surgery.
    UNASSIGNED: Our drainage strategy with BPCs decreased the incidence of postoperative complications and alleviated the postoperative pain of patients undergoing lobectomy by uniportal VATS and is safe and feasible.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    本研究旨在全面概述成人输尿管重建特有的并发症,强调他们的介绍,诊断,输尿管结构疾病的治疗和管理。
    这篇综述涉及对现有文献和案例研究有关输尿管重建的深入分析,重点检查手术后可能出现的并发症的范围。特别注意每个并发症的呈现,所涉及的诊断过程,以及后续的管理策略。
    输尿管重建术可以治疗输尿管狭窄疾病,发病率低;然而,并发症,虽然不常见,会有严重的后果。最显著的并发症包括尿外渗,狭窄复发,尿路感染,筋膜室综合征,有症状的膀胱输尿管反流,和Boari皮瓣坏死。每种并发症都提出了独特的诊断挑战,并需要特定的管理方法。
    输尿管重建术是治疗输尿管狭窄的有效方法。对输尿管重建后患者可能经历的潜在并发症有深刻的了解不仅对于充分咨询患者至关重要,而且还有助于在出现并发症时及时诊断和管理。
    UNASSIGNED: This study aimed to provide a comprehensive overview of the complications unique to ureteral reconstruction in adults, emphasizing their presentation, diagnosis, and management in the treatment of ureteral structure disease.
    UNASSIGNED: This review involves an in-depth analysis of existing literature and case studies pertaining to ureteral reconstruction, with a focus on examining the range of complications that can arise post-surgery. Special attention is given to the presentation of each complication, the diagnostic process involved, and the subsequent management strategies.
    UNASSIGNED: Ureteral reconstruction can treat ureteral stricture disease with low morbidity; however, complications, although uncommon, can have severe consequences. The most notable complications include urinary extravasation, stricture recurrence, urinary tract infections, compartment syndrome, symptomatic vesicoureteral reflux, and Boari flap necrosis. Each complication presents unique diagnostic challenges and requires specific management approaches.
    UNASSIGNED: Ureteral reconstruction is a highly effective treatment for ureteral stricture disease. Having a strong understanding of the potential complications that patients may experience following ureteral reconstruction is not only critical to adequately counsel patients but also facilitate prompt diagnosis and management of complications when they arise.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    目的:这篇综述文章的目的是提供良性输尿管-肠吻合口狭窄(UAS)治疗和结果的当代概述。
    结果:在本文中,我们将回顾调查UAS和评估病因的最新研究,潜在风险因素,介绍,诊断,和管理选项,以及从我们管理这种具有挑战性的重建并发症的经验中获得的个人见解。良性UAS是肠尿流改道的相对常见的长期并发症,影响大约十分之一的患者。它被认为是由吻合部位的输尿管组织缺血和纤维化引起的。风险因素似乎包括任何增加渗漏或缺血可能性的因素;目前尚不清楚吻合方法是否也会影响狭窄的风险。管理选项多种多样,包括内生逻辑,打开,和机器人方法。内窥镜入路的病态可能较少,但与输尿管休息一段时间后进行的重建相比,效果要少得多。
    OBJECTIVE: The purpose of this review article is to provide a contemporary overview of benign uretero-enteric anastomotic stricture (UAS) management and outcomes.
    RESULTS: In this article, we will review the most recent studies investigating UAS and evaluate etiology, potential risk factors, presentation, diagnosis, and management options, along with personal insight gained from our experience with managing this challenging reconstructive complication. Benign UAS is a relatively common long-term complication of intestinal urinary diversion, affecting approximately 1 in 10 patients. It is thought to be caused by ureteral tissue ischemia and fibrosis at the anastomotic site. Risk factors appear to include any that increase the likelihood of leak or ischemia; it is not clear if anastomotic approach impacts risk for stricture as well. Management options are varied and include endourologic, open, and robotic approaches. Endoscopic approaches may be less morbid but are considerably less effective than reconstruction performed after a period of ureteral rest.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    背景:尽管在日本,肺叶下切除术(楔形切除术[Wed]或节段切除术[Seg])已成为临床分期IA1和IA2非小细胞肺癌(NSCLC)的标准手术方法,在现实临床实践中,该手术对预后和术后并发症的影响尚不清楚.
    方法:本研究回顾性分析了2012年至2021年接受手术治疗的470例临床分期≤IA2NSCLC患者预后不良和术后并发症的危险因素。
    结果:在实变与肿瘤比率(CTR)高于0.5的患者中,Wed组(72.1%)的5年无复发生存率(RFS)明显低于Seg(85.8%)和Lob(86.8%)组(p<0.01),但Seg组和Lob组之间差异不显著。在CTR为0.5或更低的患者中,三组的5年RFS率无显著差异.RFS的多变量分析表明,Wed组的预后明显差于Lob组(风险比,2.83;p<0.01),但是Wed和Seg组之间或Seg和Lob组之间的差异不显著。术后并发症的多变量分析表明,Wed组的风险明显低于Seg组(比值比,0.31;p<0.01)。
    结论:Seg可以成为临床分期IA1和IA2NSCLC患者的标准手术程序。建议将Wed作为CTR为0.5或更低的患者的选择,并且具有避免术后并发症的优势。
    BACKGROUND: Although sublobar resection (wedge resection [Wed] or segmentectomy [Seg]) has become a standard operative procedure for clinical stages IA1 and IA2 non-small cell lung cancer (NSCLC) in Japan, the impact of this procedure on the prognosis and postoperative complications in real-world clinical practice is unknown.
    METHODS: This study retrospectively analyzed risk factors for a poor prognosis and postoperative complications of 470 patients with clinical stage ≤ IA2 NSCLC who underwent surgery from 2012 to 2021.
    RESULTS: Among the patients with a consolidation-to-tumor ratio (CTR) higher than 0.5, the 5-year relapse-free survival (RFS) rate was significantly lower in the Wed group (72.1%) than in the Seg (85.8%) and Lob (86.8%) groups (p < 0.01), but the difference between the Seg and Lob groups was not significant. Among patients with a CTR of 0.5 or lower, the 5-year RFS rate did not differ significantly among the three groups. Multivariable analysis of RFS showed that the prognosis was significantly worse in the Wed group than in the Lob group (hazard ratio, 2.83; p < 0.01), but the difference between the Wed and Seg groups or the between Seg and Lob groups was not significant. Multivariable analysis of postoperative complications showed a significantly lower risk in the Wed group than in the Seg group (odds ratio, 0.31; p < 0.01).
    CONCLUSIONS: Seg could become the standard operative procedure for clinical stages IA1 and IA2 NSCLC patients. Wed is suggested to be an option for patients with a CTR of 0.5 or lower and has the advantage of avoiding postoperative complications.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Case Reports
    脾动脉瘤(SAA)是最常见的内脏动脉瘤,如果破裂会导致严重的后果。本报告介绍了一名71岁的女性,该女性在接受胰十二指肠切除术治疗胰头癌19年后突然发生严重的胃肠道出血。病人带着休克的迹象来到医院,影像学显示SAA破裂并伴有胃穿孔。急诊治疗涉及血管内技术,稳定了病人并控制了出血.该病例强调了快速诊断的重要性和血管内治疗在治疗SAA破裂中的有效性。特别是有复杂手术史的患者。
    Splenic artery aneurysm (SAA) is the most common visceral artery aneurysm and can lead to severe outcomes if ruptured. This report presents the case of a 71-year-old female who experienced a sudden and severe gastrointestinal hemorrhage 19 years after undergoing pancreaticoduodenectomy for pancreatic head cancer. The patient arrived at the hospital with signs of shock, and imaging revealed an SAA rupture with associated gastric perforation. Emergency treatment involved endovascular techniques, which stabilized the patient and controlled the bleeding. This case highlights the importance of rapid diagnosis and the effectiveness of endovascular therapy in managing SAA rupture, particularly in patients with complex surgical histories.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    新辅助免疫疗法和化学疗法(NICT)的结合已成为局部晚期胃癌(LAGC)的常用治疗方案。然而,NICT后胃癌根治术(NICT-G)的安全性和有效性仍存在争议.本研究旨在分析影响NICT-G术后并发症(POCs)的危险因素。此外,旨在构建列线图,为预测POCs提供临床参考。
    这项研究包括2020年1月至2024年1月在中国人民解放军总医院第一医学中心接受NICT-G治疗的177名患者。单变量和多变量logistic回归模型用于评估影响POCs的危险因素,并建立了列线图模型。为了评估列线图模型的区分度和准确性,测量受试者工作特征曲线下面积(AUC)和校准曲线.
    在177名接受NICT-G的患者中,病理完全缓解率和主要病理缓解率分别为15.8%和45.2%,分别,而总体和严重治疗相关不良事件的发生率分别为71.8%和15.8%,分别。此外,43例(24.3%)患者出现总体POC(Clavien-Dindo分类≥II)。单变量和多变量逻辑分析表明,年龄≥70岁,估计失血更多,血小板/淋巴细胞比值(PLR)≤196,中性粒细胞/淋巴细胞比值(NLR)>1.33,非R0切除,体重指数(BMI)<18.5kg/m2是总体POC的独立危险因素(p<0.05)。使用上述变量建立的列线图模型显示,预测POC风险的AUC(95%置信区间[CI])为0.808(95%CI):0.731-0.885。校准曲线表明,列线图的预测曲线与实际POC拟合良好(Hosmer-Lemeshow检验:χ2=5.76,P=0.451)。
    NICT-G中总体POC的独立危险因素是年龄≥70岁,估计失血更多,PLR≤196,NLR>1.33,非R0切除,BMI<18.5kg/m2。基于上述指标建立的列线图模型在预测POC风险方面显示出更好的准确性。
    UNASSIGNED: The combination of neoadjuvant immunotherapy and chemotherapy (NICT) has become a common treatment regimen for locally advanced gastric cancer (LAGC). However, the safety and efficacy of radical gastrectomy following NICT (NICT-G) remain controversial. This study aimed to analyze the risk factors influencing postoperative complications (POCs) after NICT-G. Additionally, it aimed to construct a nomogram to provide a clinical reference for predicting POCs.
    UNASSIGNED: This study included 177 patients who received NICT-G at the Chinese PLA General Hospital First Medical Center from January 2020 to January 2024. Univariable and multivariable logistic regression models were used to evaluate the risk factors influencing POCs, and a nomogram model was constructed. To evaluate the discrimination and accuracy of the nomogram model, the area under the receiver operating characteristic curve (AUC) and the calibration curve were measured.
    UNASSIGNED: In 177 patients who received NICT-G, the pathological complete response and major pathological response rates were 15.8% and 45.2%, respectively, whereas the rates of the overall and severe treatment-related adverse events were 71.8% and 15.8%, respectively. In addition, 43 (24.3%) patients developed overall POCs (Clavien-Dindo classification ≥ II). Univariable and multivariable logistic analyses showed that age ≥70 years, greater estimated blood loss, platelet/lymphocyte ratio (PLR) ≤196, neutrophil/lymphocyte ratio (NLR) >1.33, non-R0 resection, and body mass index (BMI) < 18.5 kg/m2 were independent risk factors for overall POCs (p < 0.05). The nomogram model developed using the abovementioned variables showed that the AUC (95% confidence interval [CI]) was 0.808 (95% CI): 0.731-0.885 in predicting the POC risk. The calibration curves showed that the prediction curve of the nomogram was a good fit for the actual POCs (Hosmer-Lemeshow test: χ2 = 5.76, P = 0.451).
    UNASSIGNED: The independent risk factors for overall POCs in the NICT-G were age ≥ 70 years, greater estimated blood loss, PLR ≤ 196, NLR > 1.33, non-R0 resection, and BMI < 18.5 kg/m2. The nomogram model developed based on the abovementioned indicators showed better accuracy in predicting the POC risk.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    背景:本研究旨在评估腹膜引流及其类型对预后的影响,包括术后恢复和并发症,根据阑尾炎的等级,阑尾切除术后的儿科患者(≤16岁)。
    方法:在这项回顾性研究中,我们分析了2017年1月至2024年1月在我们中心符合纳入和排除标准的阑尾炎儿科患者(≤16岁),并根据阑尾炎的等级将其分为I-V级,V代表最严重的病例。根据引流状态和类型对患者进行分组。主要临床结果包括术后康复指标,如恢复软饮食的时间,时间来删除排水,术后抗生素使用时间和住院时间(LOH),以及术后并发症,包括腹内脓肿(IAA),肠梗阻和伤口感染(WI),手术后30天内再入院。
    结果:共有385例阑尾炎患儿被纳入研究,并分为无引流(ND)组(n=74),根据引流状态和类型,被动引流(PD)组(n=246)和主动引流(AD)组(n=65)。与其他两组相比,ND组恢复软饮食的时间明显较短,术后抗生素使用和LOH的持续时间,这些差异具有统计学意义。在I级患者中也观察到类似的发现(P<0.05)。在这里检查的所有案例中,与PD组相比,AD组的引流时间明显缩短(3.04[1-12]vs2.74[1-15],P=0.049);这种差异在I级患者中也很明显(2.80[1-6]vs2.47[1-9],P=0.019)。此外,在同一年级内,与PD组相比,仅在IV级AD组的术后抗生素使用时间较短(4.75[4-5]vs8.33[5-15],P=0.009)。此外,AD组LOH长于PD组(8.00[4-13]vs4.75[4-5],P=0.025)。在所有案件中,与其他两组相比,ND组的总体并发症和WI的发生率显着降低(P<0.05)。此外,ND组IAA发生率明显低于PD组(0%vs5.3%,P=0.008<0.0167)。此外,尽管总体并发症的发生率没有统计学上的显着差异,IAA,肠梗阻,在≥II级分析期间,PD组和AD组之间的WI(P>0.05),与AD组相比,PD组30天内的再入院率较高;差异无统计学意义(P>0.05)。此外,多变量分析显示,较高的阑尾炎级别与总体并发症和IAA的风险增加以及术后抗生素使用和LOH的持续时间更长相关。
    结论:阑尾炎分级是预测术后IAA和LOH的重要指标。在I级阑尾炎患者中,腹膜引流,即使主动排水,不推荐;对于≥II级阑尾炎患者,主动引流在减少术后抗生素使用时间和LOH方面可能比被动引流更有效.
    BACKGROUND: This study aimed to assess the impact of peritoneal drainage and its type on prognosis, encompassing postoperative recovery and complications, in pediatric patients (≤ 16 years old) following appendectomy based on the grade of appendicitis.
    METHODS: In this retrospective study, we analyzed pediatric patients (≤ 16 years old) with appendicitis who met the inclusion and exclusion criteria in our center from January 2017 to January 2024 and classified them into grade I-V based on the grade of appendicitis, with V representing the most serious cases. The patients were grouped according to drainage status and type. The main clinical outcomes included postoperative rehabilitation indexes such as time to resume a soft diet, time to remove the drain, duration of postoperative antibiotic use and length of hospitalization (LOH), as well as postoperative complications including intra-abdominal abscess (IAA), ileus and wound infection (WI), and readmission within 30 days after surgery.
    RESULTS: A total of 385 pediatric patients with appendicitis were included in the study and divided into No-drainage (ND) group (n = 74), Passive drainage (PD) group (n = 246) and Active drainage (AD) group (n = 65) according to drainage status and type. Compared to the other two groups, the ND group had a significantly shorter time to resume a soft diet, duration of postoperative antibiotic use and LOH, and these differences were statistically significant. Similar findings were observed in grade I patients too (P < 0.05). In all cases examined here, the AD group had a significantly shorter time for drain removal compared to the PD group (3.04 [1-12] vs 2.74 [1-15], P = 0.049); this difference was also evident among grade I patients (2.80 [1-6] vs 2.47 [1-9], P = 0.019). Furthermore, within the same grade, only in grade IV did the AD group exhibit a shorter duration of postoperative antibiotic use compared to the PD group (4.75 [4-5] vs 8.33 [5-15], P = 0.009). Additionally, the LOH in the AD group was longer than that in the PD group (8.00 [4-13] vs 4.75 [4-5], P = 0.025). Among all cases, the ND group exhibited significantly lower incidences of overall complications and WI compared to the other two groups (P < 0.05). Additionally, the incidence of IAA in the ND group was significantly lower than that in the PD group (0% vs 5.3%, P = 0.008 < 0.0167). Furthermore, although there were no statistically significant differences in the incidence of overall complications, IAA, ileus, and WI between the PD and AD groups during grade ≥ II analysis (P > 0.05), a higher readmission rate within 30 days was observed in the PD group compared to the AD group; however, these differences were not statistically significant (P > 0.05). Moreover, multivariate analysis revealed that a higher grade of appendicitis was associated with an increased risk of overall complications and IAA as well as a longer duration of postoperative antibiotic use and LOH.
    CONCLUSIONS: The appendicitis grade is a crucial indicator for predicting postoperative IAA and LOH. In patients with grade I appendicitis, peritoneal drainage, even if active drainage, is not recommended; For patients with grade ≥ II appendicitis, active drainage may be more effective than passive drainage in reducing the duration of postoperative antibiotic use and LOH.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    目的:术后谵妄(POD)是术后最常见的并发症之一,与许多不良结局密切相关。包括高死亡率和低生活质量。本研究旨在对2012-2022年POD及其危险因素进行文献计量分析,以揭示研究现状和热点。
    方法:本研究是文献计量和可视化分析。
    方法:2012年至2022年的相关出版物来自WebofScienceCoreCollection数据库。CiteSpace软件(v6.1.R2,德雷克塞尔大学),VOSviewer软件(v1.6.18,莱顿大学),利用文献计量在线分析平台对研究属性进行分析。这些出版物被用来分析研究属性,包括国家,期刊,机构,作者,关键词,和突发检测,预测趋势和热点。
    结果:我们包含了2012年至2022年的1,324份相关文件。自2016年以来,关于POD的文献大幅增加。美国和哈佛大学是主要的文学出版国(436/1324,32.9%)和机构(112/1324,8.5%)。《麻醉与镇痛》是发表频率最高的期刊。VOSviewer的关键词分析表明,关键词可以分为五个簇,包括麻醉技术,心脏手术,危险因素,术中麻醉监测,和术后认知功能障碍。我们共纳入了198份POD风险因素文件,有关POD危险因素的文献增多。中华人民共和国和哈佛大学是主要的文献出版国(53/198,26.8%)和机构(12/198,6.1%)。老年人,髋关节手术,脆弱,术后疼痛,心脏手术,痴呆症,抑郁症是POD的危险因素。
    结论:关于POD在麻醉领域的文献数量明显增加。危险因素和麻醉技术仍然是研究的关键领域。脑电图,使用镇静剂,围手术期护理可能是新的研究热点。老年人,髋部骨折,心脏手术,肝移植,痴呆症,抑郁症是POD危险因素领域的热词。
    OBJECTIVE: Postoperative delirium (POD) is one of the most frequent complications after surgery which is closely associated with many adverse outcomes, including high mortality and low quality of life. This study aims to carry out a bibliometric analysis of POD and its risk factors from 2012 to 2022 to reveal the research status and hot spots.
    METHODS: This study is a bibliometric and visualized analysis.
    METHODS: Relevant publications between 2012 and 2022 were extracted from the Web of Science Core Collection database. CiteSpace software (v6.1. R2, Drexel University), VOSviewer software (v1.6.18, Leiden University), and the Online Analysis Platform of Literature Metrology were used to analyze research attributes. These publications were used to analyze research attributes, including countries, journals, institutions, authors, keywords, and burst detection, to predict trends and hot spots.
    RESULTS: We included a total of 1,324 related documents from 2012 to 2022. The literature on POD has increased significantly since 2016. The United States and Harvard University were the leading literature publishing country (436/1324, 32.9%) and institution (112/1324, 8.5%). Anesthesia and Analgesia was the most frequently published journal. Keywords analysis with VOSviewer revealed that the keywords could be divided into five clusters, including anesthesia techniques, cardiac surgery, risk factors, intraoperative anesthesia monitoring, and postoperative cognitive dysfunction. We included a total of 198 POD risk factors documents, and the literature on POD risk factors increased. The People\'s Republic of China and Harvard University were the leading literature publishing country (53/198, 26.8%) and institution (12/198, 6.1%). Elderly, hip surgery, frailty, postoperative pain, cardiac surgery, dementia, and depression are keywords that are risk factors for POD.
    CONCLUSIONS: The number of literature on POD in the field of anesthesia has increased significantly. Risk factors and anesthesia techniques are still key areas of research. Encephalogram, the use of sedatives, and perioperative nursing may be the new research focus. Older adults, hip fractures, cardiac surgery, liver transplants, dementia, and depression are hot words in the field of POD risk factors.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    目的:本研究旨在阐明隆突下转移模式,胸段食管鳞状细胞癌的左、右喉返神经淋巴结清扫及探讨相应的淋巴结清扫策略。
    方法:对2020年12月至2024年4月行食管切除术的胸段食管鳞癌患者进行回顾性分析。隆突下的危险因素,采用卡方检验和多因素logistic回归分析确定左、右喉返神经淋巴结转移。我们根据不同的临床病理特征可视化了这些特定淋巴结的转移率。隆突下之间的相关性,同时分析左右喉返淋巴结转移及术后并发症。
    结果:共纳入503例胸段食管鳞癌患者行食管切除术。隆突下的转移率,左右喉返神经淋巴结占10.3%,10.3%,10.9%,分别。淋巴管浸润状态和肿瘤位置是隆下和右喉返神经淋巴结转移的重要预测因素,分别为(P<0.001和P=0.013)。对于左喉返神经淋巴结转移,年龄较小(P=0.020)和淋巴管浸润(P=0.009)是显著的危险因素.此外,肺部感染是隆突下夹层术后最常见的并发症,左右喉返淋巴结。吻合口漏发生率差异无统计学意义(P=0.872)。肺部感染(P=0.139),乳糜胸(P=0.702),隆突下淋巴结清扫队列和保留队列之间的声音嘶哑(P=0.179)。与保留队列相比,右侧(P=0.042)和左侧(P=0.010)喉返神经淋巴结清扫队列的声音嘶哑发生率显着增加,发病率分别为5.9%和6.7%,分别。
    结论:隆突下转移率,胸段食管鳞癌中左右喉返神经淋巴结均超过10%。隆突下淋巴结清扫术不会增加术后并发症风险,喉返神经淋巴结清扫术显著增加了声音嘶哑的发生率。因此,隆突下淋巴结的淋巴结清扫应常规进行,而喉返神经淋巴结清扫术可以在特定患者中选择性进行。
    OBJECTIVE: This research aimed to clarify the metastatic patterns of subcarinal, right and left recurrent laryngeal nerve lymph nodes in thoracic esophageal squamous cell carcinoma and to investigate appropriate strategies for lymph node dissection.
    METHODS: Patients with thoracic esophageal squamous cell carcinoma receiving esophagectomy from December 2020 to April 2024 were retrospectively analyzed. Risk factors for subcarinal, right and left recurrent laryngeal nerve lymph nodes metastasis were determined by chi-square test and multivariate logistic regression analysis. We visualized the metastasis rates of these specific lymph nodes based on the different clinicopathological characteristics. Correlation between subcarinal, right and left recurrent laryngeal lymph nodes metastasis and postoperative complications were also analyzed.
    RESULTS: A total of 503 thoracic esophageal squamous carcinoma patients who underwent esophagectomy were enrolled. The metastasis rates of subcarinal, right and left recurrent laryngeal nerve lymph nodes were 10.3%, 10.3%, and 10.9%, respectively. The lymphovascular invasion status and tumor location were the significant predictors for subcarinal and right recurrent laryngeal nerve lymph nodes metastasis, respectively (P < 0.001 and P = 0.013). For left recurrent laryngeal nerve lymph node metastasis, younger age (P = 0.020) and presence of lymphovascular invasion (P = 0.009) were significant risk factors. Additionally, pulmonary infection is the most frequent postoperative complication in patients with dissection of subcarinal, right and left recurrent laryngeal lymph nodes. There was no significant difference in the incidence of anastomotic leakage (P = 0.872), pulmonary infection (P = 0.139), chylothorax (P = 0.702), and hoarseness (P = 0.179) between the subcarinal lymph node dissection cohort and the reservation cohort. The incidence of hoarseness significantly increased in both right (P = 0.042) and left (P = 0.010) recurrent laryngeal nerve lymph nodes dissection cohorts compared by the reservation cohorts, with incidence rates of 5.9% and 6.7%, respectively.
    CONCLUSIONS: The metastasis rates of subcarinal, right and left recurrent laryngeal nerve lymph nodes in thoracic esophageal squamous cell carcinoma were all over 10%. The dissection of subcarinal lymph nodes does not increase postoperative complications risk, while recurrent laryngeal nerve lymph nodes dissection significantly increases the incidence of hoarseness. Thus, lymph node dissection of subcarinal lymph nodes should be conducted routinely, while recurrent laryngeal nerve lymph nodes dissection may be selectively performed in specific patients.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    目的:分析肾移植患者糖脂代谢指标的变化及其对术后并发症发生率的影响。目的是为临床实践和可靠安全实施RT提供参考。
    方法:选取2019年1月至2024年3月在我院接受RT治疗的131例患者进行回顾性分析:出现术后并发症的患者71例(研究组),未出现并发症的患者60例(对照组)。空腹血糖(FPG)的差异,糖化血红蛋白(HbA1c),术前和术后3天的总胆固醇(TC)和甘油三酯(TG)水平进行比较,并分析其对术后并发症的预测价值。此外,确定影响RT后并发症的相关因素。
    结果:两组术后HbA1c水平均无明显变化(p>0.05),但是FPG,两组TG和TC水平均升高(p<0.05)。观察组手术前后FPG、TC水平差异均大于对照组(p<0.05)。受试者工作特征曲线显示FPG和TC水平差异对术后并发症的诊断价值。Logistic回归分析显示,上述差异是放疗后并发症的独立危险因素(p<0.05)。
    结论:可以通过监测RT前后FPG和TC水平的差异来早期评估术后并发症,允许及时制定和实施干预措施。
    OBJECTIVE: Changes in glucolipid metabolism parameters in patients undergoing renal transplantation (RT) and their influences on the incidence of postoperative complications were analysed. The objective was to provide a reference for clinical practice and reliable and safe implementation of RT.
    METHODS: A total of 131 patients treated with RT at our institution from January 2019 to March 2024 were selected for retrospective analysis: 71 patients who developed postoperative complications (research group) and 60 patients who did not (control group). Differences in fasting plasma glucose (FPG), glycosylated haemoglobin (HbA1c), total cholesterol (TC) and triglyceride (TG) levels before and three days after surgery were compared, and their predictive value for postoperative complications was analysed. In addition, relevant factors influencing complications after RT were identified.
    RESULTS: HbA1c level changed significantly in neither group after surgery (p > 0.05), but FPG, TG and TC levels increased in both groups (p < 0.05). Differences in FPG and TC levels before and after surgery were larger than those in the control group (p < 0.05). The receiver operating characteristic curve revealed the excellent diagnostic value of differences in FPG and TC levels for postoperative complications, and logistic regression analysis indicated that such differences were independent risk factors for complications after RT (p < 0.05).
    CONCLUSIONS: The early evaluation of postoperative complications can be achieved by monitoring differences in FPG and TC levels before and after RT, allowing for the timely formulation and implementation of interventions.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

公众号