Obsessive compulsive disorder

强迫症
  • 强迫症(OCD)在症状内容和洞察力方面是临床上异质性的精神疾病。
    研究强迫症中与洞察力相关的各种因素。
    对40名强迫症患者进行了一项基于医院的横断面研究,这些患者采用耶鲁-布朗强迫症量表进行了评估,汉密尔顿焦虑量表,汉密尔顿抑郁量表,布朗信念评估量表,元认知问卷,WHOQOL-BREF,和希恩残疾量表。使用SPSS版本22进行统计学分析。
    元认知,强迫症的严重程度,和相关残疾是强迫症患者自知力的重要预测因素。
    与OCD的洞察力相关的因素可以增强我们对OCD管理的理解。
    UNASSIGNED: Obsessive compulsive disorder (OCD) is a clinically heterogeneous psychiatric disorder in terms of symptom content and insight.
    UNASSIGNED: To study the various factors associated with insight in OCD.
    UNASSIGNED: A cross-sectional hospital-based study was conducted among 40 patients with OCD who were evaluated on Yale-Brown Obsessive-Compulsive Scale, Hamilton Anxiety Rating Scale, Hamilton Depression Rating Scale, Brown Assessment of Beliefs Scale, Meta-Cognitions Questionnaire, WHOQOL-BREF, and Sheehan Disability Scale. Statistical analysis was done using SPSS version 22.
    UNASSIGNED: Metacognition, severity of OCD, and associated disability were the significant predictors for insight in patients with OCD.
    UNASSIGNED: Factors associated with insight in OCD can enhance our understanding in the management of OCD.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    患有强迫症(OCD)的服务用户通常会因为害怕与强迫症和强迫症相关的判断或羞耻感而延迟或避免寻求诊断或治疗。他们可能觉得自己的行为违背了社会规范,这会导致社会孤立,反过来,进一步加剧了健康不平等。当这些人出现身体疾病并被地区护士看到时,必须适当地理解和处理行为。重要的是发展治疗关系并考虑其整体福祉。作为一个多学科团队,与心理健康团队建立密切的工作关系,并将团队用作资源,可能有助于OCD服务用户的整体健康结果。
    Service users living with Obsessive compulsive disorder (OCD) often delay or avoid seeking diagnosis or treatment because of a fear of judgement or feelings of shame associated with their obsessions and compulsions. They may feel that their behaviour defies societal norms, which can lead to social isolation, and in turn, further contribute to health inequality. When such individuals present with physical illness and are seen by district nurses, it is imperative that behaviours are understood and approached appropriately. It is important to develop therapeutic relationships and consider their holistic wellbeing. Developing a close working relationship with the mental health team as a multidisciplinary team and using the team as a resource may contribute to the overall health outcome of service users with OCD.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Editorial
    暂无摘要。
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    本研究旨在介绍一种间歇性theta爆发刺激(iTBS)和连续theta爆发刺激(cTBS)双重刺激治疗产后强迫症(OCD)的情况。目的是在药物和心理治疗不是首选或禁忌的情况下提供可参考的治疗方法。此病例进一步强调了非侵入性神经调节技术在改善产后OCD患者病情中的重要性。
    一名32岁女性在分娩后2个月被诊断为强迫症。由于担心会干扰婴儿的母乳喂养,患者拒绝服用药物和心理治疗。随后,进行为期2周的iTBS和cTBS联合治疗。病人的强迫症状,焦虑,抑郁症改善。治疗期间无明显不良反应,治疗结束后2周,治疗效果仍保持。
    该临床病例提供了证据,表明iTBS和cTBS联合治疗可在短期内潜在地有效缓解强迫症状。值得注意的是,这种治疗方法可能为产后强迫症患者提供有希望的解决方案,因为它解决了实际问题,如母乳喂养母亲的药物安全和这一人群的具体需求。为了进一步确定这种联合疗法的疗效,未来需要大样本随机对照试验和长期随访,以验证其治疗潜力.
    UNASSIGNED: This study aimed to present a case of intermittent theta-burst stimulation (iTBS) and continuous theta-burst stimulation (cTBS) dual stimulation for the treatment of postpartum obsessive-compulsive disorder (OCD). The objective was to provide a referenceable therapy in cases where medication and psychotherapy treatment are not preferred or contraindicated. This case further emphasized the importance of non-invasive neuromodulation techniques in improving the condition of postpartum OCD patients.
    UNASSIGNED: A 32-year-old female was diagnosed with OCD 2 months after delivery. The patient refused to take medication and psychotherapy due to concerns that it would interfere with the infant\'s breastfeeding. Subsequently, a 2-week combined iTBS and cTBS treatment was carried out. The patient\'s obsessive-compulsive symptoms, anxiety, and depression improved. There were no significant adverse effects during the treatment, and the treatment effect remained 2 weeks after the end of the treatment.
    UNASSIGNED: This clinical case provides evidence that the combined iTBS and cTBS treatment can potentially effectively alleviate obsessive-compulsive symptoms in the short term. Notably, this therapeutic approach may offer a promising solution for postpartum OCD patients, as it addresses practical concerns such as medication safety for breastfeeding mothers and the specific needs of this population. To further establish the efficacy of this combined therapy, future randomized controlled trials with large samples and long-term follow-up are warranted to validate its therapeutic potential.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    强迫症(OCD)已经脱颖而出,特别是COVID-19大流行可以说是在工作生活范围内被忽视的。出于这个原因,有必要进行组织心理学研究,以检查工作生活中的OCB。
    本研究的目的是研究员工的强迫症倾向与工作成瘾和工作压力的关系。
    定量研究旨在达到研究目的。共有771名白领员工完成了一项调查,其中包括上述三个变量的心理评估工具。
    相关分析表明,强迫症与工作成瘾(p<0.001)和工作压力(p<0.001)均呈正相关。多元回归分析表明,反思性(OCD量表上的一个子量表)与工作成瘾(β=0.39p<0.001)和工作压力(β=0.40p<0.001)显着相关。
    从理论上解释了所获得的发现,凭经验,实际上,并讨论了有关工作生活中强迫症检查的可能研究建议。
    UNASSIGNED: Obsessive-compulsive disorder (OCD) which has come to the fore, especially with the COVID-19 pandemic is arguably neglected within the scope of working life. For this reason, there is a need for research in organizational psychology to examine OCB in working life.
    UNASSIGNED: The purpose of the present study was to examine the associations of OCD tendencies of employees with work addiction and job stress.
    UNASSIGNED: Quantitative research was designed to achieve the research purpose. A total of 771 white-collar employees completed a survey that included psychometric assessment tools for the three aforementioned variables.
    UNASSIGNED: Correlation analysis indicated that OCD was positively associated with both work addiction (p < 0.001) and job stress (p < 0.001). Multiple regression analysis showed that the rumination (a subscale on the OCD scale) was significantly associated with work addiction (β= 0.39 p < 0.001) and job stress (β= 0.40 p < 0.001).
    UNASSIGNED: The obtained findings are interpreted theoretically, empirically, and practically, and possible research suggestions regarding the examination of OCD in working life are discussed.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    目的:亲人对强迫症(OCD)症状的适应非常普遍,对治疗结果有影响;然而,对影响强迫症患者浪漫伴侣住宿的因素知之甚少。这项初步调查的目的是探索这种相关性。
    方法:一个社区样本,包括50名自我识别患有OCD的患者(Mage=29.3;SD=9.3;74%女性)和20名自我识别为OCD患者的伴侣(Mage=32.1;SD=12.4;65%女性)通过在线问卷参加了这项研究。
    结果:发现了强迫症的伴侣调节与患者和伴侣样本中的一系列强迫症和强迫症之间的关联,以及患者报告的症状严重程度,功能障碍和负面情绪状态。在患者样本中,神经质也与伴侣适应呈正相关,但在其他已知的家庭适应相关因素之外,对其预测没有贡献。在合作伙伴样本中,发现外向性是伴侣适应性的独特负相关。
    结论:这些发现强调了患者和伴侣因素在浪漫伴侣适应强迫症行为中的重要作用,以及让亲人参与治疗强迫症患者的重要性。
    OBJECTIVE: The accommodation of symptoms of obsessive-compulsive disorder (OCD) by loved ones is highly prevalent and impactful on treatment outcomes; however, little is known about factors that influence accommodation by romantic partners of OCD sufferers. The aim of this preliminary investigation was to explore such correlates.
    METHODS: A community sample of 50 patients self-identifying with OCD (Mage = 29.3; SD = 9.3; 74% female) and 20 individuals self-identifying as the partner of someone with OCD (Mage = 32.1; SD = 12.4; 65% female) participated in this study via an online questionnaire.
    RESULTS: Associations were found between partner accommodation of OCD and a range of obsessions and compulsions across the patient and partner samples, as well as patient-reported symptom severity, functional impairment and negative emotion states. Neuroticism was also positively associated with partner accommodation in the patient sample but did not contribute to its prediction over and above other known correlates of family accommodation. In the partner sample, extraversion was found to be a unique negative correlate of partner accommodation.
    CONCLUSIONS: These findings highlight the vital role both patient and partner factors play in the accommodation of OCD behaviours by romantic partners and the importance of involving loved ones in the treatment of individuals with OCD.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    托林等人。(2004)开发了传染任务链(CCT),以实验方式测试传染规律和迫在眉睫的脆弱性(LV)。在CCT中,受污染的铅笔与干净的铅笔接触。转移到更多新铅笔的污染程度是指有偏见的传染性信念的水平。虽然这可能是一个重要的诊断工具,原始范例的可用性非常费力。因此,在研究1中,一项有85名参与者的非临床样本中引入并验证了基于图像和视频的CCT.在研究2中,基于图像的CCT在一项临床研究中得到了验证,其中15名参与者被诊断为与污染相关的强迫症(C-OCD)。15名患有焦虑症的参与者,和15个非临床对照。参与者的数量与Tolin的原始样本中的参与者数量一致,并且研究2的统计评估是预先注册的。两种CCT都可以验证,结果可以复制。在基于图像的CCT中,C-OCD组显示出更高的污染等级,回避倾向和LV优于两个对照组。我们认为,这种开放式获取诊断仪器可以应用于研究和治疗实践(下载CCT视频和图像:https://doi.org/10.5281/zenodo.7730459)。
    Tolin et al. (2004) developed the Chain of Contagion Task (CCT) to experimentally test the law of contagion and looming vulnerability (LV). In the CCT, contaminated pencils are brought into contact with clean pencils. The degree of contamination transferred to further new pencils refers to the level of biased contagious beliefs. Although this could be an important transdiagnostic tool, the usability of the original paradigm has been very laborious. Therefore, an imagery- and video-based CCT is introduced and validated in Study 1 in a nonclinical sample with 85 participants. In Study 2, the imagery-based CCT was validated in a clinical study with 15 participants diagnosed with contamination-related obsessive-compulsive disorder (C-OCD), 15 participants suffering from an anxiety disorder, and 15 nonclinical controls. The number of participants is consistent with those in Tolin\'s original sample and the statistical evaluation of Study 2 was preregistered. Both CCT could be validated and the results could be replicated. In the imagery-based CCT, the C-OCD group displayed significantly higher contamination ratings, avoidance tendencies and LV than the two control groups. We argue that this open access diagnostic instrument can be applied in research as well as in therapeutic practice (Download CCT videos and imagery: https://doi.org/10.5281/zenodo.7730459).
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

  • 文章类型: Journal Article
    精神病合并症已被证明是一个一贯的挑战。最近的方法强调需要从症状簇的分类描述转向精神障碍的维度视图。从现象学精神病理学的角度来看,这种转变是不够的,更详细地了解病人的生活经历也是必要的。一种现象学的方法表明,我们可以通过个性化的网络模型更好地了解精神疾病的性质,以显著节点的形式全面描述一个人的生活世界以及它们之间的关系。我们提供了一个有多种合并症的患者的详细案例研究,适应不良的应对机制,和不利的童年经历。
    此案被追踪了两年,在此期间,我们收集了多个数据流,从现象学访谈,神经心理学评估,语言分析,和半结构化访谈(反常的自我经验的检查和反常的世界经验的检查)。我们分析构建了他的生活世界的个性化网络模型。
    我们确定了一个经验类别“客观性危机”作为他生活世界的核心心理病理学主题。它指的是他对他获得的任何信息的持续不信任,他认为这些信息源于他的主观性。我们可以从发展上追溯到他不利的童年经历的客观性危机,以及他认真经历精神病发作。为了弥补精神病症状,他开发了各种适应不良的应对机制。有趣的是,我们发现了他的主观报告和其他数据来源之间的对应关系。
    Hernan在多个研究领域标准构建中表现出困难。虽然我们可以说社会感觉运动,正价,和负效价系统功能障碍可能与原发性缺陷(起源于他不利的童年经历)有关,他的认知症状可能与他的适应不良应对机制有关(尽管,它们也可能与他的原发性疾病有关)。
    UNASSIGNED: Psychiatric comorbidities have proven a consistent challenge. Recent approaches emphasize the need to move away from categorical descriptions of symptom clusters towards a dimensional view of mental disorders. From the perspective of phenomenological psychopathology, this shift is not enough, as a more detailed understanding of patients\' lived experience is necessary as well. One phenomenology-informed approach suggests that we can better understand the nature of psychiatric disorders through personalized network models, a comprehensive description of a person\'s lifeworld in the form of salient nodes and the relationships between them. We present a detailed case study of a patient with multiple comorbidities, maladaptive coping mechanisms, and adverse childhood experiences.
    UNASSIGNED: The case was followed for a period of two years, during which we collected multiple streams of data, ranging from phenomenological interviews, neuropsychological assessments, language analysis, and semi-structured interviews (Examination of Anomalous Self Experience and Examination of Anomalous World Experience). We analytically constructed a personalized network model of his lifeworld.
    UNASSIGNED: We identified an experiential category \"the crisis of objectivity\" as the core psychopathological theme of his lifeworld. It refers to his persistent mistrust towards any information that he obtains that he appraises as originating in his subjectivity. We can developmentally trace the crisis of objectivity to his adverse childhood experience, as well as him experiencing a psychotic episode in earnest. He developed various maladaptive coping mechanisms in order to compensate for his psychotic symptoms. Interestingly, we found correspondence between his subjective reports and other sources of data.
    UNASSIGNED: Hernan exhibits difficulties in multiple Research Domain Criteria constructs. While we can say that social sensorimotor, positive valence, and negative valence systems dysfunctions are likely associated with primary deficit (originating in his adverse childhood experience), his cognitive symptoms may be tied to his maladaptive coping mechanisms (although, they might be related to his primary disorder as well).
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    前囊切开术是难治性强迫症(OCD)的治疗选择之一。过去已经证明了伽玛刀囊切开术(GKC)的安全性和有效性。
    使用基于fixel的分析(FBA)和可能的疗效预测因子来表征GKC引起的变化。
    对其他治疗无效的强迫症患者进行双侧GKC治疗,最大剂量为120Gy内囊前肢(ALIC)。临床结果是Yale-Brown强迫症量表(Y-BOCS)的减少百分比。使用基于fixel的纤维密度(FD)分析(FBA)的白质变化,光纤束横截面(FC)和两者的组合(FDC)。
    7名患者接受了GKC。中位随访时间为13个月(12-58个月)。最后一次随访时Y-BOCS评分的平均(±SD)下降为61%±35%,其中五名患者被视为响应者。FBA在ALIC中显示出对称的FD减少,并延伸到前额丘脑辐射;在两个半球中,沿着上纵向束(SLF)的FC减少,在左侧占优势。FDC的减少主要在右半球检测到,具有与FD减少相似的模式,并且与Y-BOCS减少与腹侧部分通过的纤维之间呈正相关(p<0.05)。
    GKC在降低部分患者的OCD严重程度方面是安全有效的。GKC诱导的白质变化在ALIC上延伸。通过右侧ALIC腹侧部分的纤维的减少与更好的结果相关。
    UNASSIGNED: Anterior capsulotomy is one of the therapeutic options for refractory obsessive-compulsive disorder (OCD). Safety and efficacy of Gamma Knife Capsulotomy (GKC) have been demonstrated in the past.
    UNASSIGNED: To characterize changes induced by GKC using a fixel-based analysis (FBA) and possible predictors of efficacy.
    UNASSIGNED: Patients with OCD refractory to other therapies underwent bilateral GKC with 120 Gy as a maximum dose on the anterior limb of the internal capsule (ALIC). The clinical outcome was percent reduction in Yale- Brown Obsessive-Compulsive Scale (Y-BOCS). White Matter changes were analyzed using fixel-based analysis (FBA) for fibre density (FD), fibre-bundle cross-section (FC) and the combination of the two (FDC).
    UNASSIGNED: Seven patients underwent GKC. Median follow-up was 13 months (range 12-58 months). Mean (±SD) decrease in Y-BOCS score at last follow-up was 61 % ± 35 % with five patients considered as responders. FBA showed a symmetric FD reduction in the ALIC with extension to the anterior fronto-thalamic radiation; a reduction of FC along the superior longitudinal fasciculus (SLF) in both hemispheres with a predominance in the left one. Reductions in FDC were detected predominantly in the right hemisphere, with a similar pattern to FD reductions and associated with a positive correlation (p < 0.05) between Y-BOCS reduction and fibres passing in the ventral part.
    UNASSIGNED: GKC is safe and efficient in reducing OCD severity in selected patients. Changes induced in white matter by GKC extend over the ALIC. Reduction of fibres passing the ventral part of the right sided ALIC correlates with better results.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

       PDF(Pubmed)

  • 文章类型: Journal Article
    目标:以其致残性质为特征,强迫症(OCD)对个体影响深远,近40%的患者对最初的治疗方法表现出抵抗力。尽管安全且易于接近,经颅直流电刺激(tDCS)缺乏支持其治疗强迫症疗效的广泛证据。这项研究的目的是评估阴极高清经颅直流电刺激(HD-tDCS)如何应用于右眶额叶皮质对强迫症患者的疗效。
    方法:纳入47例强迫症患者。他们被随机分配到活动或假刺激组,行HD-tDCS刺激治疗2周。位于右眶额叶皮质区域的中心电极为阴极。患者强迫症状的严重程度,在治疗前后评估抑郁和焦虑。
    结果:在总数中,44例患者结束治疗,包括23名来自主动刺激组的参与者和21名来自假刺激组的参与者。值得注意的是,与强迫症相关的症状大幅减少,抑郁症,两组均表现出焦虑。主动刺激组有效率为26.1%,假刺激组有效率为23.8%。观察到的疗效没有显着差异。此外,治疗结束时抑郁和焦虑症状的减轻在主动刺激组中并不显著优于对照组.
    结论:本研究为HD-tDCS的可接受性和安全性提供了证据。然而,与假刺激组相比,该研究未显示tDCS在治疗中度至重度OCD方面的显著临床有效性.
    OBJECTIVE: Characterized by its disabling nature, obsessive compulsive disorder (OCD) affects individuals profoundly, with nearly 40% of patients showing resistance to initial treatment methods. Despite being safe and easily accessible, transcranial direct current stimulation (tDCS) lacks extensive substantiation supporting its efficacy in treating OCD. The objective of this study was to evaluate how cathodal high-definition transcranial direct current stimulation (HD-tDCS) applied to the right orbitofrontal cortex affected patients with OCD in terms of efficacy.
    METHODS: 47 patients with OCD were enrolled. They were randomly allocated to active or sham stimulation groups, and underwent HD-tDCS stimulation treatment for 2 weeks. The central electrode located in the right orbitofrontal cortex region was cathodic. The severity of the patients\' obsessive-compulsive symptoms, depression and anxiety were assessed before and after treatment.
    RESULTS: Out of the total, 44 patients concluded the treatment, comprising 23 participants from the active stimulation group and 21 from the sham stimulation group. Notably, substantial reductions in symptoms related to OCD, depression, and anxiety were exhibited in both groups. With a response rate of 26.1% in the active stimulation group and 23.8% in the sham stimulation group, there was no significant difference in efficacy observed. Furthermore, the reduction in depression and anxiety symptoms at the conclusion of the treatment was not notably superior in the active stimulation group.
    CONCLUSIONS: This study provided evidence for the acceptability and safety of HD-tDCS. Nevertheless, the study did not reveal notable clinical effectiveness of tDCS in addressing moderate to severe OCD in comparison to the sham stimulation group.
    导出

    更多引用

    收藏

    翻译标题摘要

    我要上传

    求助全文

公众号