背景:隐孢子虫是一种原虫寄生虫引起隐孢子虫腹泻,这通常是一种短暂的良性感染,但在免疫受损的个体中可能变得严重且无法解决。本研究的目的是确定在哈马丹地区与牲畜接触的牲畜和人类中隐孢子虫感染的患病率。伊朗。
方法:在这项横断面研究中,共收集了660个粪便标本;228、195和237个来自人类,他们饲养牲畜,它们的小牛和羔羊/山羊,分别在2012年春季。通过福尔马林-醚浓缩技术浓缩样品并使用冷改良的Ziehl-Neelsen染色法检查。
结果:人类粪便样本中的228个样本中有2个(0.87%),195个样本中有25个(12.8%),237个样本中有6个(2.5%),小牛和羔羊/山羊的隐孢子虫卵囊呈阳性,分别。隐孢子虫感染与人类人口统计学变量之间没有显着关系。然而,腹泻型小牛隐孢子虫感染率较高(OR=3.81;95%CI:1.30,11.21;P=0.010)。
结论:尽管在伊朗一些地区进行的研究导致与牲畜接触的人类感染率相对较高,我们的结果显示哈马丹地区无症状人群的患病率低,携带者状态低.因为小牛和羔羊/山羊的感染率相对较高,这些动物可能是该地区人类感染的可能宿主。
BACKGROUND: Cryptosporidium is a protozoan parasite causes cryptosporidial diarrhea, which is typically a short-lasting benign infection, but can become severe and non-resolving in immunocompromised individuals. The aim of the present study was to determinate the prevalence of Cryptosporidium infection in livestock and humans that were in contact with livestock in Hamadan district, Iran.
METHODS: In this cross sectional study a total of 660 fecal specimens were collected; 228, 195 and 237 from humans, whom raising livestock, their calves and lambs/goats, respectively in spring 2012. Samples were concentrated by formalin-ether concentration technique and examined using cold modified Ziehl-Neelsen staining method.
RESULTS: Two (0.87%) out of 228, 25 (12.8%) out of 195 and 6 (2.5%) out of 237 fecal samples of humans, calves and lambs/goats were positive for Cryptosporidium oocysts, respectively. There was no significant relationship between the infection to Cryptosporidium and demographic variables of humans. However, Cryptosporidium infection rate was higher in diarrheic calves (OR=3.81; 95% CI: 1.30, 11.21; P=0.010).
CONCLUSIONS: Despite studies conducted in some regions of Iran that resulted in a relatively high rate of infection in humans in contact with livestock, our results showed low prevalence and low carrier status in the asymptomatic persons in Hamadan region. Because the infection in calves and lambs/goats was relatively high, these animals could be probable reservoir of infection for humans in this area.