关键词: Cryptosporidium Modified Ziehl-Neelsen cryptosporidiosis opportunistic infections saffranine-methylene blue yellow nail syndrome

Mesh : Humans Infant Cryptosporidiosis / complications diagnosis drug therapy Cryptosporidium Yellow Nail Syndrome / complications diagnosis Immunocompromised Host Diarrhea / parasitology Feces / parasitology

来  源:   DOI:10.2174/1871526522666220920142423

Abstract:
Cryptosporidium species infection causes malabsorption and severe diarrhea in immunocompromised hosts. Association of Yellow Nail Syndrome (YNS) and Cryptosporidiosis is rare and has not been reported till date. Immunity can also be affected in this case of YNS is associated with autoimmune disorders.
Here, we describe a case of persistent diarrhea in an 8 month old YNS patient. Modified Ziehl-Neelsen staining and Saffranine-Methylene blue revealed oocyts of Cryptosporidium species. Following appropriate treatment, the patient\'s symptoms improved and the patient was discharged in a hemodynamically stable condition.
Cryptosporidiosis is a significant cause of morbidity and mortality in immunocompromised patients. YNS per se as well as treatment including steroids leads to immunosuppression in individuals making them susceptible host for opportunistic infections like Cryptosporidiosis.
Clinicians should be aware of the condition and screen for Cryptosporidiosis in any immunocompromised patients with diarrheal symptoms, as parasitic infection like this are opportunistic in them.
摘要:
背景:隐孢子虫感染导致免疫受损宿主的吸收不良和严重腹泻。黄甲综合征(YNS)和隐孢子虫病的关联很少见,迄今为止尚未报道。在这种情况下,由于YNS与自身免疫性疾病有关,因此免疫力也受到影响。
方法:这里,我们描述了一例8个月大YNS患者的持续性腹泻病例.改良的ZiehlNeelsen染色和沙红碱-亚甲基蓝揭示了隐孢子虫的卵。经过适当的治疗,患者的症状改善并在血流动力学稳定的情况下出院。
结论:隐孢子虫病是免疫功能低下患者发病和死亡的重要原因。YNS本身以及包括类固醇在内的治疗导致个体的免疫抑制,使其对诸如隐孢子虫病的机会性感染易感。
结论:临床医生应了解病情,并在任何具有腹泻症状的免疫功能低下患者中筛查隐孢子虫病。因为像这样的寄生虫感染是机会主义的。
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