Iraq

伊拉克
  • 文章类型: Journal Article
    肩锁关节(ACJ)脱位和锁骨远端骨折是常见的肩关节损伤。不同的固定方法用于治疗这种损伤,每个都有其优点和缺点。在这项研究中,我们用钩板测试了固定。我们认为这在技术上很简单,在某些手术情况下可靠且更有效。然而,由于钢板放置的潜在并发症,包括肩峰下骨溶解,它没有得到足够的普及,撞击,肩袖损伤等。传统上需要进行第二次钢板切除手术以应对此类并发症。
    本研究的目的包括评估钩钢板内固定治疗ACJ脱位和锁骨远端骨折的临床和放射学愈合情况,以及评估肩峰下骨溶解的发生率和临床意义。
    这是一项前瞻性观察性研究,共96例,包括64例ACJ脱位和32例锁骨远端骨折。Constant-Murley评分用于临床评估。定期对患者进行评估,最低随访时间为去除钢板后12个月。
    在研究结束时,我们发现两组的钩板固定结果在临床和放射学上都很好。发现ACJ脱位患者的临床结果评分最初较高,这主要是由于这些患者较早地切除了钢板。然而,两组的最终评分具有可比性.发现锁骨骨折患者肩峰下骨溶解的发生率更高,因为钢板保留的时间更长。然而,我们发现,肩峰下骨溶解并不意味着与X线片上未显示这种并发症的患者相比,症状的发生率有任何增加。
    基于这些观察,我们建议将钩板固定添加到整形外科医生的医疗设备中,因为它易于实施,经久耐用,能够处理困难的情况。这种方法的主要缺点是需要第二次手术来去除钢板。
    UNASSIGNED: Acromioclavicular joint (ACJ) dislocation and distal clavicle fractures are common shoulder injuries. Different methods of fixation are used to treat such injuries, each has its advantages and disadvantages. In this study, we tested fixation using the hook plate. We think that it is technically simple, reliable and more effective in certain surgical situations. However, it is not gaining adequate popularity due to the potential complications of the plate placement including subacromial osteolysis, impingement, rotator cuff injury and others. A second surgery for plate removal is classically indicated to cope with such complications.
    UNASSIGNED: The aim of this study included evaluating the clinical and radiological healing after hook plate fixation in ACJ dislocation and distal clavicle fractures and assessing the incidence and clinical significance of subacromial osteolysis.
    UNASSIGNED: It is a prospective observational study with a total of 96 cases including 64 ACJ dislocations and 32 distal clavicle fractures. Constant-Murley score was used for clinical evaluation. The patients were evaluated regularly with a minimum follow up of 12 months after plate removal.
    UNASSIGNED: At the end of the study we found that the results of the hook plate fixation for both groups were good clinically and radiologically. The clinical result score was found to be initially higher among the patients of the ACJ dislocation mainly due to the earlier plate removal in these patients. However, the final score was found to be comparable in both groups. The incidence of the subacromial osteolysis was found to be higher among the patients with clavicle fractures as the plate was retained for a longer time. However we found that subacromial osteolysis did not imply any increased rate of symptoms over the patients who did not show this complication on the X-ray.
    UNASSIGNED: Based on these observations, we recommend the hook plate fixation to be added to the armamentarium of the orthopaedic surgeon treating such injuries as it is simple to implement, durable and capable of dealing with difficult situations. The main disadvantage of this method is the need for a second surgery for plate removal.
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  • 文章类型: Journal Article
    Dega截骨术越来越广泛地用于治疗发育性髋关节发育不良(DDH)。
    由于许多技术方面尚未完全定义,因此需要对此程序进行全面描述。此外,还需要更多的后续系列来评估其结果。
    在这项研究中,我们对该手术进行了详细的解剖学描述,并介绍了我们作为回顾性影像学和病例记录研究的经验.我们检查了44例(48髋)不同程度的DDH患者的临床和影像学记录。
    患者平均年龄为2个月和7个月,平均随访时间为41个月。进行了临床和影像学评估,包括CT和3D重建以检查截骨术的解剖特征。我们发现同心减少了93.7%,具有出色的临床和影像学结果。只有3例需要修正Dega截骨术。再次手术率为12.5%。CT扫描显示,在大多数情况下,截骨穿过弓形线。在20.7%的病例中,我们发现,原本打算做Dega截骨术的骨切口,在不经意间被实施为另一种截骨术变体.然而,这对结果没有显著影响。
    我们发现,实施良好的Dega截骨术是应对DDH髋臼变化的可靠工具。
    UNASSIGNED: Dega osteotomy is becoming more widely used for the treatment of developmental dysplasia of the hip (DDH).
    UNASSIGNED: A thorough description of this procedure is needed as many of the technical aspects are not fully defined. Moreover, more follow-up series are also needed to evaluate its outcomes.
    UNASSIGNED: In this study, we gave a detailed anatomic description for this procedure and also presented our experience as a retrospective radiographic and case-note study. We examined the clinical and radiographic records of 44 patients (48 hips) with varying degrees of DDH.
    UNASSIGNED: The average age of the patients was 2 months and 7 months while the average follow up period was 41 months. Clinical and radiographic assessment including CT with 3D reconstruction to examine the anatomic characteristics of the osteotomy were undertaken. We found that concentric reduction was achieved in 93.7% with excellent clinical and radiographic outcomes. Only 3 cases needed revision of the Dega osteotomy. The re-operation rate was 12.5%. CT scan revealed that the arcuate line was crossed by the osteotomy in the majority of cases. In 20.7% of cases, a bone cut that was intended to be a Dega osteotomy was found to have been inadvertently implemented as another osteotomy variant. However, this bore no significant effect on the outcome.
    UNASSIGNED: We found that a well-implemented Dega osteotomy is a reliable tool to cope with the acetabular changes in DDH.
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  • 文章类型: Journal Article
    分析SNPs(rs1801131和rs1801133)中MTHFR基因的遗传变异与伊拉克类风湿关节炎(RA)患者的治疗结果之间的关系。该研究是对95名伊拉克RA患者进行的。根据他们的治疗反应,该队列分为两组:应答者(47例患者)和无应答者(48例患者),在甲氨蝶呤(MTX)治疗至少三个月后鉴定。采用聚合酶链反应-限制性片段长度多态性(PCR-RFLP)技术分析MTHFR变异,特别是在rs1801133和rs1801131。总的来说,rs1801131遵循共同主导和主导模式,在共支配模型中,与TT基因型相比,GG[OR(95%CI)0.11(0.022-0.553)]和TG[OR(95%CI)0.106(0.021-0.528)]预测反应者;同时,对于主导模型,与TT基因型相比,GG和TG基因型[OR(95%CI)0.108(0.023-0.507)]的存在共同预测应答者.Ars1801133Grs1801131单倍型与应答者显著相关[OR(95%CI):0.388(0.208-0.723)],而Grs1801133Trs1801131单倍型与无反应者略有相关[OR(95%CI)1.980(0.965-4.064)].在最后的多变量分析中,GG/TGrs1801131基因型在调整患者后与应答者独立相关,疾病,和治疗特点,而TTrs1801131基因型与无反应者相关。伊拉克RA患者显示MTHFR基因rs1801131的遗传多态性,T携带者等位基因与MTX治疗无反应者相关。rs1801131遵循共显性和显性模型。rs1801131的G携带等位基因在调整患者后显示出与MTX治疗应答者的独立关联,疾病,和治疗特点。
    Analyze the relationship between genetic variations in the MTHFR gene at SNPs (rs1801131 and rs1801133) and the therapy outcomes for Iraqi patients with rheumatoid arthritis (RA). The study was conducted on a cohort of 95 RA Iraqi patients. Based on their treatment response, the cohort was divided into two groups: the responder (47 patients) and the nonresponder (48 patients), identified after at least three months of methotrexate (MTX) treatment. A polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) technique was employed to analyze the MTHFR variations, specifically at rs1801133 and rs1801131. Overall, rs1801131 followed both codominant and dominate models, in which in the codominant model, GG [OR (95% CI) 0.11 (0.022-0.553)] and TG [OR (95% CI) 0.106 (0.021-0.528)] predict responders compared to the TT genotype; meanwhile, for the dominate model, the presence of both GG and TG genotypes [OR (95% CI) 0.108 (0.023-0.507)] together predict responders compared to the TT genotype. The Ars1801133Grs1801131 haplotype was significantly associated with responders [OR (95% CI): 0.388 (0.208-0.723)], while the Grs1801133Trs1801131 haplotype was associated marginally with nonresponders [OR (95% CI) 1.980 (0.965-4.064)]. In the final multivariate analysis, GG/TGrs1801131 genotypes were independently related to responders after adjustment for patients, disease, and treatment characteristics, while TTrs1801131 genotypes were associated with nonresponders. The Iraqi RA patients showed genetic polymorphism in MTHFR gene rs1801131 with T carrier allele associated with nonresponders to MTX therapy. The rs1801131 followed both codominant and dominant models. The G-carried allele for rs1801131 showed an independent association with responder to MTX therapy after adjustment for patients, disease, and treatment characteristics.
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  • 文章类型: Journal Article
    背景:克里米亚-刚果出血热病毒(CCHFV)在伊拉克流行,在过去的五年中,不断观察到反复流行的流行病。本研究旨在确定2022年DhiQar省与克里米亚-刚果出血热(CCHF)病例相关的因素。
    方法:采用检测阴性病例对照设计分析621例CCHF患者,其中162例确诊,459例为疑似病例。为了识别确诊和疑似病例,使用逆转录聚合酶链反应(RT-PCR)。选取PCR检测结果阴性的可疑患者作为对照组。收集了有关CCHF潜在风险因素的数据,作为DhiQar省相同地理位置的前几年的现有数据。Logistic回归分析用于确定可能的危险因素与确诊的CCHF病例之间的相关性。
    结果:CCHF的发生率为每100,000人中6.8%。病死率为7.7%的患者死亡总数为48例。患者年龄从1岁到65岁不等,总体平均值±SD为36.08±18.29年。98.2%的患者年龄在15至65岁之间;58%的报告患者为男性,男女比例为1.4:1。此外,与生肉接触,动物接触,在CCHF阳性病例中,蜱咬伤的百分比最高。
    结论:男性,像家庭主妇这样的高风险工作,卫生工作人员,牧羊人,屠夫,动物贩子,屠宰场工人,兽医人员,和农民,蜱叮咬,与生肉的接触是2022年DhiQar省CCHF发病率增加的有统计学意义的预测因素。
    BACKGROUND: Crimean-Congo hemorrhagic fever virus (CCHFV) is endemic in Iraq, where recurrent epidemics have been constantly observed during the last five years. The present study aimed to determine the factors associated with Crimean-Congo hemorrhagic fever (CCHF) cases in Dhi Qar province during the year 2022.
    METHODS: A test-negative case-control design was used to analyze 621 CCHF patients, of which 162 were confirmed and 459 were suspected cases. To identify the confirmed and suspected cases, reverse transcriptase polymerase chain reaction (RT-PCR) was used. Suspected patients whose PCR test results were negative were selected as the control group. Data on potential risk factors for CCHF were collected as existing data for previous years for the same geographical locations in Dhi Qar province. Logistic regression analyses were used to determine the correlation between probable risk factors and confirmed CCHF cases.
    RESULTS: The incidence rate of CCHF was 6.8% per 100,000 people. The total number of deaths was 48 for patients with a case fatality rate of 7.7%. The patients\' ages ranged from one year to 65 years, with an overall mean ± SD of 36.08 ± 18.29 years. A total of 98.2% of the patients were between 15 and 65 years of age; 58% of the reported patients were male, and the male-to-female ratio was 1.4:1. Additionally, contact with raw meat, animal contact, and tick bite had the highest percentages for CCHF positivity cases.
    CONCLUSIONS: Male gender, high-risk jobs like housewives, health staff, shepherds, butchers, animal dealers, slaughterhouse workers, veterinary staff, and farmers, tick bites, and contact with raw meat were statistically significant predictors for increasing CCHF incidence in Dhi Qar province during the year 2022.
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  • 文章类型: Editorial
    这篇社论探讨了社会转型对伊拉克妇女生活的影响,特别是关于美容标准和美容程序,如抽脂。它考察了现代化的影响,社交媒体,和社会压力与传统保守价值观并列。从镇压政权向更加开放的过渡,尽管不稳定,政治景观导致了女性角色的重大转变,保守主义的增加与新兴的现代主义影响形成鲜明对比。社交媒体在放大现代美丽理想中的作用为女性努力平衡这些理想与传统期望造成了内部冲突。对美容程序的日益接受表明,伊拉克社会正在向整合现代美容标准转变。
    This editorial explores the impact of societal transformation on Iraqi women\'s lives, particularly concerning beauty standards and cosmetic procedures like liposuction. It examines the influences of modernization, social media, and social pressures juxtaposed with traditional conservative values. The transition from repressive regimes to more open, albeit unstable, political landscapes has led to significant shifts in women\'s roles, with increased conservatism contrasting with emerging modernist influences. The role of social media in amplifying modern beauty ideals creates internal conflicts for women striving to balance these with traditional expectations. The growing acceptance of cosmetic procedures indicates a shift toward integrating modern beauty standards within Iraqi society.
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  • 文章类型: Journal Article
    背景:冠状病毒病19(COVID-19),一种由称为严重急性呼吸道综合症冠状病毒2(SARS-COV-2)的病毒引起的传染病,于2019年在中国发现,并导致几种轻度至中度呼吸系统疾病。这项研究旨在通过研究依诺肝素的作用并评估IL-10作为疾病活动标志物的潜力,揭示伊拉克COVID-19患者与健康对照组相比血清白介素10(IL-10)和其他参数的变化。
    方法:这是一项病例对照研究,包括180个样本:2022年11月至2023年4月20日90例COVID-19住院患者(40例患者从未使用过依诺肝素,而50例患者服用了依诺肝素)和90例健康,年龄和性别匹配的控制。其中女性患者44例,男性患者46例。患者和对照组的平均年龄为53.8岁。50.8年,分别。夹心酶联免疫吸附试验(ELISA)方法测定IL-10水平,而其他参数使用比色法进行评估。
    结果:研究结果表明,患者和健康对照组之间的IL-10,D-二聚体,和C反应蛋白(CRP)水平,以及肝和肾功能。这些发现阐明了依诺肝素患者与非依诺肝素患者在IL-10、D-二聚体、和CRP水平。然而,肝肾功能无明显改变.Spearman秩相关检验探讨血清IL-10与CRP的关系。
    结论:结果显示IL-10和CRP之间有很强的正相关关系。其他分析参数之间没有显着差异;因此,患者的IL-10、D-二聚体、和一些其他参数比健康控制。此外,IL-10可用作疾病活动的标志物。依诺肝素可能有助于控制患者的IL-10和D-二聚体浓度,因为依诺肝素治疗的患者IL-10水平降低。
    BACKGROUND: Coronavirus disease 19 (COVID-19), an infectious disease resulting from a virus known as severe acute respiratory syndrome coronavirus 2 (SARS-COV-2), was discovered in China in 2019 and causes several mild to moderate respiratory conditions. This study aimed to reveal the changes in serum interleukin-10 (IL-10) and other parameters in Iraqi COVID-19 patients compared with healthy controls by studying the effects of enoxaparin and evaluating the potential of IL-10 as a disease activity marker.
    METHODS: This was a case-control study that included 180 samples: 90 patients hospitalized with COVID-19 from November 2022 to 20 April 2023 (40 patients had never used enoxaparin, whereas 50 patients had taken enoxaparin) and 90 healthy, age- and sex-matched control. There were 44 female patients and 46 male patients. The mean age of the patients and controls was 53.8 years vs. 50.8 years, respectively. The sandwich enzyme-linked immunosorbent assay (ELISA) method was used to measure IL-10 levels, while other parameters were assessed using the colorimetric method.
    RESULTS: The results of the study indicated highly significant changes between the patients and healthy controls in IL-10, D-dimer, and C-reactive protein (CRP) levels, as well as liver and renal functions. These findings elucidated a significant change between enoxaparin patients and non-enoxaparin patients in IL-10, D-dimer, and CRP levels. However, the liver and renal functions were not significantly altered. The Spearman\'s rank correlation test investigated the relationship between serum IL-10 and CRP.
    CONCLUSIONS: The results displayed a strong positive relationship between IL-10 and CRP. There were no significant differences between the other analyzed parameters; consequently, the patients had higher concentrations of IL-10, D-dimer, and some other parameters than the healthy controls. Additionally, IL-10 may be used as a marker of disease activity. Enoxaparin will likely help control IL-10 and D-dimer concentrations in patients since IL-10 levels decreased in patients treated with enoxaparin.
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  • 文章类型: Journal Article
    沙门氏菌感染被认为是引起人畜共患感染和食物中毒的最常见的食源性病原体。抗菌素耐药性被认为是全球性的焦虑,因为它会引起人类公共卫生的影响,以及导致动物发病率和死亡率的增加。
    本研究的目的是分离和鉴定肠沙门氏菌,以及使用聚合酶链反应(PCR)和从鸡肉产品(鸡蛋,肝脏,和肉末)和伊拉克瓦西特省的人类。
    总共300个样品(150个鸡肉产品样品,包括鸡蛋,肝脏,还有肉末,和150个人类粪便样本)于2022年1月至12月从伊拉克瓦西特省收集。根据ISO6579标准和全球食源性感染网络实验室协议的建议进行细菌分离。根据临床和实验室标准研究所的建议,通过使用19种抗生素进行血清分型测试和AST。2022年通过使用圆盘扩散敏感性测试和Vitik2测试。最后,使用常规PCR方法和一个独特的rRNA基因测序确认可疑分离株.
    结果表明,鸡肉产品中肠链球菌的分离率为8.66%(鸡蛋的12%,6%的肝脏,和8%的肉末),而在人类中,它是4.6%。此外,在人类中显示出100%的伤寒沙门氏菌。同时,在鸡蛋伤寒中,鼠伤寒沙门氏菌,肠炎沙门氏菌占50%,33.33%,和16.66%,分别。此外,在肝脏和肉末中均显示出100%的鼠伤寒沙门氏菌。人体分离物中的AST对氨苄青霉素具有抗性,头孢噻肟,头孢他啶,头孢吡肟,阿米卡星,庆大霉素,环丙沙星,诺氟沙星,和头孢曲松,虽然对阿莫西林没有抗药性,Pipracillin,Ertapenem,亚胺培南,美罗培南,磷霉素,呋喃妥因,甲氧苄啶,阿奇霉素,和四环素.在鸡肉产品中,分离株对阿米卡星耐药率不同,庆大霉素,四环素,环丙沙星,诺氟沙星,呋喃妥因,氨苄青霉素,头孢噻肟,头孢他啶,头孢吡肟,和甲氧苄啶;虽然对阿莫西林没有抗药性,Pipracillin,Ertapenem,亚胺培南,美罗培南,磷霉素,阿奇霉素,和头孢曲松.使用rRNA基因对四种PCR产物进行测序。
    这项研究表明肠链球菌的基因突变的存在,导致分子特征的变化,从鸡肉产品和人类中分离出的肠球菌的耐药性。
    UNASSIGNED: Salmonella infections are considered the most common foodborne pathogens responsible for zoonotic infections and food poisoning in humans and animal species such as birds. Antimicrobial resistance is considered a global anxiety because it causes human public health repercussions, as well as leads to an increase in animal morbidity and death.
    UNASSIGNED: The aims of this study are the isolation and identification of Salmonella enterica, as well as to investigate the antimicrobial susceptibility test (AST) and the molecular characteristics using polymerase chain reaction (PCR) and sequences for isolates from chicken products (eggs, livers, and minced meat) and human in the Wasit Governorate of Iraq.
    UNASSIGNED: A total of 300 samples (150 chicken product samples including eggs, livers, and minced meat, and 150 human fecal samples) were collected from the Wasit governorate of Iraq from January to December 2022. The bacterial isolation was done according to recommendations of ISO 6579 standard and the Global Foodborne Infections Network laboratory protocol. Serotyping test and AST were done by using 19 antibiotic agents according to the recommendations of the Clinical and Laboratory Standards Institute, 2022 by using disc diffusion susceptibility test and Vitik 2 test. Finally, the suspected isolates were confirmed using the conventional PCR method and sequencing for a unique rRNA gene.
    UNASSIGNED: The results showed that the isolation percentage of S. enterica in chicken products was 8.66% (12% eggs, 6% livers, and 8% minced meat), while in humans it was 4.6%. Also, showed 100% of Salmonella typhi in humans. While, in chicken eggs S. typhi, Salmonella typhimurium, and Salmonella enteritidis were 50%, 33.33%, and 16.66%, respectively. Also, showed 100% of S. typhimurium in both livers and minced meat. The AST in human isolates showed resistance to Ampicillin, Cefotaxime, Ceftazidime, Cefepime, Amikacin, Gentamicin, Ciprofloxacin, Norfloxacin, and Ceftriaxone, while no resistance to Amoxicillin, Pipracillin, Ertapenem, Imipenem, Meropenem, Fosfomycin, Nitrofurantoin, Trimethoprim, Azithromycin, and Tetracycline. In chicken products, isolates were resistant with different percentages to Amikacin, Gentamicin, Tetracycline, Ciprofloxacin, Norfloxacin, Nitrofurantoin, Ampicillin, Cefotaxime, Ceftazidime, Cefepime, and Trimethoprim; while no resistance to Amoxicillin, Pipracillin, Ertapenem, Imipenem, Meropenem, Fosfomycin, Azithromycin, and Ceftriaxone. Sequencing by using rRNA gene was done for four PCR products.
    UNASSIGNED: This study showed the presence of genetic mutations for S. enterica which led to variations in the molecular characteristics, and antimicrobial drug resistance of S. enterica isolated from chicken products and humans.
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  • 文章类型: Journal Article
    β-葡聚糖(β-葡聚糖)是含有β-糖苷键的多糖,是不同酵母细胞的重要结构部分。
    研究的目的是表征从白色念珠菌获得的β-葡聚糖(C.白色念珠菌)从山羊乳腺炎中分离出来。
    通过使用碱性-酸性提取技术提取β-葡聚糖。提取的β-葡聚糖的干重为7.47/150g,其中4.98%。
    结果表明,与标准形式的β-葡聚糖相比,使用高效液相色谱法提取的β-葡聚糖在液体样品的主峰5.78中具有相似性。然而,扫描电子显微镜研究表明,β-葡聚糖的标准在形态上不同,但与从白色念珠菌中分离的β-葡聚糖相似,粒径在1.60-2.65m范围内,并且缺乏细胞壁痕迹。使用能量色散X射线荧光光谱法(EDS/EDX)对提取的和标准的β-葡聚糖进行调查的结果,显示发现的主要元素是碳(C),氧(O),和氮(N)。铝(Al),硅(Si),镍(Ni),金(Au)也存在,但数量较少。
    提取的β-葡聚糖与标准的β-葡聚糖表现出高度的相似性和纯度,根据傅里叶变换红外光谱(FT-IR)的研究结果。
    UNASSIGNED: Beta-glucan (β-glucan) is a polysaccharide containing β-glycosidic bonds that is an important structure part of different yeast cells.
    UNASSIGNED: The purpose of the study is to characterize β-glucan obtained from Candida albicans (C. albicans) isolated from caprine mastitis.
    UNASSIGNED: The β-glucan was extracted by using utilizing an Alkaline-acidic extraction technique. The dry weight of extracted β-glucan was 7.47/150 g with 4.98%.
    UNASSIGNED: The findings demonstrated that the extracted β-glucan had similarity in the primary peak 5.78 of liquid samples using the method of high-performance liquid chromatography when compared to the standard form of β-glucan. However, scanning electron microscopy studies revealed that the standard of β-glucan was distinct in morphology but similar to β-glucan isolated from C. albicans in terms of particle sizes in the range of 1.60-2.65 m and the lack of cell wall traces. The findings of an investigation using energy-dispersive X-ray fluorescence spectroscopy (EDS/EDX) of extracted and standard β-glucan, showed the principal elements discovered were carbon (C), oxygen (O), and nitrogen (N). Aluminum (Al), silicon (Si), nickel (Ni), and gold (Au) were also present, but in less amounts.
    UNASSIGNED: The extracted β-glucan displayed a high degree of similarity and purity to the standard β-glucan, according to the findings of Fourier transform infrared spectroscopy (FT-IR) research.
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  • 文章类型: Journal Article
    空气暴露对眼睛表面的影响是一个需要探索的领域,特别是鉴于平民和军事环境中发生的事件越来越多。在这项研究中,基于包含软件应用组合和技术生态系统的平台的计算机模拟方法用于测试伊拉克烧伤坑和东巴勒斯坦的数据中潜在的表面眼部毒性,俄亥俄州,火车脱轨.此分析的目的是更好地了解这种暴露于眼表的长期影响以及表面刺激的表现,包括干眼症。计算机模拟方法用于确定对化合物的眼部刺激。从许多公开来源引入了此类化学品的清单,用于燃烧坑和火车脱轨。结果表明,这些暴露事件中存在的某些化学物质的眼部刺激评分很高。这样的分析旨在为已经接近烧伤坑或火车出轨的个体以及未来将经历毒性暴露的个体提供与所需的眼科护理和随访相关的指导。
    The effect of airborne exposure on the eye surface is an area in need of exploration, particularly in light of the increasing number of incidents occurring in both civilian and military settings. In this study, in silico methods based on a platform comprising a portfolio of software applications and a technology ecosystem are used to test potential surface ocular toxicity in data presented from Iraqi burn pits and the East Palestine, Ohio, train derailment. The purpose of this analysis is to gain a better understanding of the long-term impact of such an exposure to the ocular surface and the manifestation of surface irritation, including dry eye disease. In silico methods were used to determine ocular irritation to chemical compounds. A list of such chemicals was introduced from a number of publicly available sources for burn pits and train derailment. The results demonstrated high ocular irritation scores for some chemicals present in these exposure events. Such an analysis is designed to provide guidance related to the needed ophthalmologic care and follow-up in individuals who have been in proximity to burn pits or the train derailment and those who will experience future toxic exposure.
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  • 文章类型: Journal Article
    背景:这项研究调查了难民和寻求庇护儿童的健康问题和医疗保健需求,并旨在制定改善策略。
    方法:根据448名难民和寻求庇护儿童以及222名非难民当地儿童的定量数据,这项研究是在杜兹斯大学进行的,儿科,2010年至2021年。难民儿童来自三个国家:伊拉克(n=304),叙利亚(n=101)和阿富汗(n=43)。使用SPSS数据分析程序对数据进行分析。道德许可是从杜兹尔伦理委员会获得的。
    结果:结果表明,难民和寻求庇护儿童的急性疾病或感染率明显较高,营养不良(p<0.001)和贫血(p<0.001)比当地儿童生活在过度拥挤的家庭(p=0.017)和不健康的条件。由于难民儿童的童婚,青少年怀孕(p=0.049)成为一个重要的社会问题,主要以近亲结婚的形式(p<0.001)。叙利亚难民女孩中至少有两次青少年怀孕(18岁以下)的比率最高(p=0.01)。尽管难民和寻求庇护儿童的健康保险费率较高(在74%至95%之间),与当地儿童相比,他们的保险费率较低。本研究还比较了来自三个民族的数据,包括叙利亚,阿富汗和伊拉克儿童;在国际保护(IP)制度下,社会支持和权利有限的伊拉克和阿富汗儿童与其他群体相比,健康状况更差。尽管伊拉克儿童入院时的医疗保险率最高(p<0.001),他们的慢性病发病率也更高(p=0.001),感染(p=0.004),过敏性鼻炎(p=0.001)和营养不良(p<0.001)。入院年龄最小(p=0.006)和住院时间最短(p=0.004)的阿富汗儿童上呼吸道感染率也较高(p=0.021)。
    结论:本研究强调了迫切需要改进筛查计划,以及合作努力解决这些人群的特定健康需求的重要性。解决儿童难民的健康状况是一项复杂和多方面的任务,需要医疗保健专业人员的积极参与,决策者和研究人员,每个人都可以发挥至关重要的作用。
    BACKGROUND: This study examines the health problems and healthcare needs of refugee and asylum-seeker children and aims to develop strategies for improvement.
    METHODS: Based on quantitative data from 448 refugee and asylum-seeker children and 222 non-refugee local children, this study was conducted at Düzce University, Department of Paediatrics, between 2010 and 2021. The refugee children originated from three countries: Iraq (n = 304), Syria (n = 101) and Afghanistan (n = 43). The data were analysed using the SPSS data analysis program. Ethical clearance was obtained from the Ethics Committee of Düzce Üniversity.
    RESULTS: The results suggest that refugee and asylum-seeker children have significantly higher rates of acute illness or infection, malnutrition (p < 0.001) and anaemia (p < 0.001) than local children as a result of living in overcrowded families (p = 0.017) and unhealthy conditions. Adolescent pregnancy (p = 0.049) emerges as an important social problem as a result of child marriage among refugee children, mostly in the form of consanguineous marriages (p < 0.001). The rate of having at least two adolescent pregnancies (under 18) was highest among Syrian refugee girls (p = 0.01). Although refugee and asylum-seeker children have higher rates of health insurance (between 74% and 95%), they have lower rates of insurance compared to local children. This research also compares the data from three nationalities, including Syria, Afghanistan and Iraq children; Iraqi and Afghan children under the international protection (IP) system with limited social support and rights had worse health conditions compared to other groups. Although Iraqi children had the highest rates of health insurance on admission (p < 0.001), they also had higher rates of chronic diseases (p = 0.001), infections (p = 0.004), allergic rhinitis (p = 0.001) and malnutrition (p < 0.001). The youngest age of admission (p = 0.006) and the shortest length of stay (p = 0.004) were for Afghan children who also had higher rates of upper respiratory infections (p = 0.021).
    CONCLUSIONS: This study highlights the urgent need for improved screening programmes and the importance of collaborative efforts to address the specific health needs of these populations. Addressing the health status of child refugees is a complex and multifaceted task that requires the active participation of healthcare professionals, policymakers and researchers, each of whom has a crucial role to play.
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