■这项研究的目的是确定腹腔疾病(CD)患者中避免/限制性食物摄入障碍(ARFID)的患病率,并评估代谢并发症,疾病控制,饮食依从性,以及与症状和生活质量指标的相关性。
■这是一项对137名成人CD患者的回顾性研究,他们在2018年至2020年之间在CD诊所完成了ARFID调查。人口统计,临床结果,标准化饮食评估,并回顾了乳糜泻症状日记和无麸质饮食问卷的影响。测量的主要结果是基于患者报告的调查响应的怀疑ARFID的比率。
■78名患者(57%)符合疑似ARFID标准。年龄没有差异,性别,身体质量指数,微量营养素缺乏,或患有或不患有ARFID的骨骼疾病。与非ARFID患者相比,ARFID患者在活检活动或对无麸质饮食的依从性方面没有差异。食物和社会负担对无麸质饮食问卷的影响最能预测ARFID。
■ARFID很常见,对CD患者影响很大。虽然有些饮食行为肯定是由于他们的CD,有或没有怀疑ARFID的患者在疾病控制方面没有明显差异,这表明这些不适应的行为不是疾病控制所必需的。我们没有发现代谢并发症增加,但这是两年的快照.我们需要进一步了解社会和食物对在这项调查中得分高的患者的影响,以防止进一步的缺陷和损害,长期有害的饮食行为。
UNASSIGNED: The objective of this study was to identify the prevalence of avoidant/restrictive food intake disorder (ARFID) in patients with celiac disease (CD) and assess metabolic complications, disease control, diet adherence, and correlation with symptom and quality-of-life metrics.
UNASSIGNED: This was a retrospective study of 137 adult patients with CD who completed an ARFID survey in the CD clinic between 2018 and 2020. Demographics, clinical results, standardized diet assessment, and results of Celiac Disease Symptom Diary and Impact of a Gluten-free Diet Questionnaire were reviewed. The primary outcome measured was the rate of suspected ARFID based on patient-reported survey responses.
UNASSIGNED: Seventy-eight patients (57%) met suspected ARFID criteria. There were no differences in age, gender, body mass index, micronutrient deficiencies, or bone disease in those with or without ARFID. Patients with ARFID did not have a difference in biopsy activity or better adherence to a gluten-free diet compared with non-ARFID patients. Food and social burden on Impact of a Gluten-free Diet Questionnaire was most predictive of ARFID.
UNASSIGNED: ARFID is common and has a high impact in patients with CD. Although some eating behavior is certainly due to their CD, there was no distinct difference in disease control between those with or without suspected ARFID, suggesting these maladaptive behaviors are not necessary for disease control. We did not find increased metabolic complications, but this was a 2-year snapshot. We need to further understand the social and food impacts on patients who score high on this survey to prevent further deficiencies and impaired, long-term detrimental eating behaviors.