■先天性乳糜胸和腹水的预后范围从自发消退到死亡,但是没有确定的检查来预测预后。我们旨在开发一种临床有用的方法,使用吲哚菁绿(ICG)淋巴造影评估先天性乳糜胸和腹水婴儿的淋巴异常。
■我们回顾性评估了2012年至2022年在我们医院接受ICG淋巴造影的先天性乳糜胸和乳糜腹水婴儿。评估了ICG淋巴造影结果。我们将躯干中的真皮回流定义为从肢体末端通过躯干表面的淋巴管返回的淋巴流。躯干皮肤回流与临床结果之间的关联,如下,进行了调查:排水期的持续时间,气管内插管的持续时间,以及住院时间的长短。
■20名婴儿在躯干皮肤回流,十个没有。躯干有和没有皮肤回流的婴儿的临床结果如下(中位数):引流期的持续时间(20vs.0天,p=0.001),气管插管的持续时间(12vs.2天,p=0.04),和住院时间(62vs.41天,p=0.04),分别。在校正胎龄的多元线性回归分析中,引流期的持续时间与躯干皮肤回流相关[exp(B)=2.62;p=0.003].
■ICG淋巴造影中躯干的真皮回流有助于预测先天性乳糜胸和腹水的临床病程。
UNASSIGNED: The prognosis of congenital chylothorax and ascites ranges from spontaneous resolution to death, but no established examination exists to predict the prognosis. We aimed to develop a clinically useful method to evaluate lymphatic abnormalities using indocyanine green (ICG) lymphography in infants with congenital chylothorax and ascites.
UNASSIGNED: We retrospectively evaluated infants with congenital chylothorax and chylous ascites who underwent ICG lymphography in our hospital between 2012 and 2022. The ICG lymphography findings was evaluated. We defined the dermal backflow in the trunk as the lymphatic flow from the end of the limb back through the lymphatic vessels on the surface of the trunk. The association between the dermal backflow in the trunk and clinical outcomes, as follows, are investigated: the duration of the drainage period, the duration of endotracheal intubation, and the length of hospital stay.
UNASSIGNED: Twenty infants had a dermal backflow in the trunk, and ten did not. Clinical outcomes in infants with and without dermal backflow in the trunk were as follows (median): the duration of the drainage period (20 vs. 0 days, p = 0.001), the duration of endotracheal intubation (12 vs. 2 days, p = 0.04), and the length of hospital stay (62 vs. 41 days, p = 0.04), respectively. In multivariate linear regression analysis adjusted for gestational age, the duration of the drainage period was correlated with the dermal backflow in the trunk [exp(B) = 2.62; p = 0.003].
UNASSIGNED: The dermal backflow in the trunk in ICG lymphography was useful in predicting the clinical course of congenital chylothorax and ascites.