生物素(B7)作为抗氧化剂,因为它抑制了许多在生物体内自然形成的自由基的作用。本研究旨在确定在暴露于氧化应激的肉仔鸡饲粮中添加不同浓度的生物素对生产和生理性能的影响。使用了180只无性别的Ross-308一天龄的肉鸡小鸡,他们一起饲养直到7天。然后将小鸡随机分为5个处理;每个处理包括3个重复,每个重复12只小鸡。通过向饮用水中添加0.5%H2O2来诱导氧化应激。第一次治疗,T1(控制),不添加B7或H2O2,并且第二处理(T2):是阳性对照处理,不添加维生素B7+水以平均0.5%的H2O2添加。第三处理(T3):添加550微克B7/kg进料+水,以平均0.5%添加H2O2。第四处理(T4):650微克/千克维生素B7+水,平均添加0.5%H2O2。第五处理(T5):750微克维生素B7/kg饲料+0.5%H2O2加入水中。在暴露于氧化应激的T4和T5鸟类的日粮中添加维生素B7的结果表明,平均活体重显着增加(P<0.05),总增重和累计饲料消耗平均值,和处理的鸟类的最佳累积饲料转化率(T3,T4,T5)。与其他疗法相比,所有额外的维生素B7处理显示葡萄糖浓度显着降低(P<0.05),胆固醇,甘油三酯,以及丙二醛(MDA),低密度脂蛋白(LDL)和高密度脂蛋白(HDL)和总蛋白的浓度显着增加(P<0.05)。与所有其他处理相比,T5处理的禽类血清中谷胱甘肽过氧化物酶(GSH-Px)的浓度显着升高(P<0.05)。我们得出的结论是,与阴性和阳性对照相比,添加不同浓度的维生素B7可以提高暴露于诱导氧化应激的肉仔鸡的生产力和一些生理特性。
Biotin (B7) acts as an antioxidant, as it inhibits the effect of many free radicals that are naturally formed within the organism\'s body. This study aimed to determine the effect of adding different concentrations of biotin to the diet of broilers exposed to oxidative stress in improving productive and physiological performance. 180 unsexed Ross-308 one-day age chicks of broiler chickens were used, and they were reared together until 7 days. Then the chicks were randomly distributed into 5 treatments; each treatment included 3 replicates, 12 chicks for each replicate. Oxidative stress was induced by adding 0.5% H2O2 to drinking water. The first treatment, T1 (control), was free from adding B7 or H2O2, and the second treatment (T2): was a positive control treatment free from adding vitamin B7 + water added to it H2O2 at an average of 0.5%. The third treatment (T3): adding 550 micrograms of B7/kg of feed + water added H2O2 at an average of 0.5%. Fourth treatment (T4): 650 micrograms/kg vitamin B7 + water with 0.5% H2O2 added on average. Fifth treatment (T5): 750 micrograms of vitamin B7/kg of feed + 0.5% H2O2 added to the water. The results of adding vitamin B7 to the diet of T4 and T5 birds exposed to oxidative stress showed a significant increase (P<0.05) in the average live body weight, total weight gain and cumulative feed consumption average, and the best cumulative feed conversion ratio for treated birds (T3, T4, T5). In comparison to the other therapies, all additional vitamin B7 treatments demonstrated a significant decrease (P<0.05) in the concentrations of glucose, cholesterol, triglycerides, as well as Malondialdehyde (MDA), and low-density lipoproteins (LDL) and a significant increase (P<0.05) in the concentrations of high-density lipoproteins (HDL) and total protein. The concentration of glutathione peroxidase (GSH-Px) was significantly elevated (P<0.05) in the serum of T5-treated birds compared to all other treatments. We conclude that adding vitamin B7 in different concentrations improved the productivity and some physiological traits of broilers exposed to the induced oxidative stress compared with the negative and positive control treatments.