semicircular canal plugging

  • 文章类型: Journal Article
    (1)背景:患有梅尼埃病的患者可以经历Tumarkin综合征,其特征是姿势不稳定,步态异常,and,偶尔,突然失去平衡,称为前庭跌落发作或Tumarkin危机。在这项研究中,建议将半规管堵塞作为这种情况的最终治疗方法。讨论了这种手术的结果。(2)方法:对9例确诊为Ménière病的Tumarkin危象患者进行后半规管封堵术。这些患者用视频头部冲动测试进行评估,前庭诱发的肌源性电位,术前和术后的纯音测听仪。(3)结果:VHIT显示术后PSC增益中位数降低(术前。0.86和POSTOP。0.52;p<0.009)。前半规管和外侧半规管无统计学差异。手术治疗后无患者出现新的Tumarkin危象。(4)结论:我们在Ménière病患者Tumarkin综合征的后半规管堵塞的十年经验表明,这种手术方法可以成功控制Tumarkin的危机。患者满意度高,听力水平几乎没有恶化。
    (1) Background: Patients affected by Ménière\'s disease can experience Tumarkin\'s syndrome, which is characterized by postural instability, gait abnormalities, and, occasionally, an abrupt loss of balance known as vestibular drop attack or Tumarkin\'s crisis. In this study, semicircular canal plugging is proposed as the definitive treatment for this condition. The outcomes of this type of surgery are discussed. (2) Methods: A total of 9 patients with a confirmed diagnosis of Ménière disease suffering from Tumarkin crisis underwent posterior semicircular canal plugging. These patients were assessed with Video Head Impulse Tests, vestibular evoked myogenic potentials, and Pure Tone Audiometry preoperatively and postoperatively. (3) Results: VHIT showed a postoperative decrease in PSC gain median (Preop. 0.86 and postop. 0.52; p < 0.009). No statistically significant differences were described for the anterior semicircular canal and the lateral semicircular canal. No patient experienced new Tumarkin crisis after the surgical treatment. (4) Conclusions: Our ten years of experience with posterior semicircular canal plugging in Ménière disease patients with Tumarkin\'s syndrome has shown that this type of surgical procedure is successful in controlling Tumarkin\'s crisis, with high patient satisfaction and little worsening in hearing level.
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  • 文章类型: Journal Article
    梅尼埃病(MD)的特征是特发性内淋巴水肿(ELH)。频繁的眩晕发作是MD的最致残症状。
    本研究评估了三支半规管闭塞联合内淋巴囊减压治疗MD患者频发性眩晕的疗效。
    在2021年5月至2022年4月进行的这项研究中,纳入了11名具有完整病历的患者。所有患者均接受三支半规管闭塞(TSCO)内淋巴囊减压(ESD)治疗。各种测试,包括纯音测听法(PTA),前庭诱发肌源性电位(VEMPs),视频头脉冲测试(v-HIT),热量测试数据,头晕障碍清单(DHI),伯格平衡量表(BBS),和耳鸣障碍量表(THI)在手术前后进行。
    在平均23个月的术后随访期间,眩晕的成功控制率为100%(9/9),完全控制率88.89%(8/9),实质控制率11.11%(1/9)。
    三重半规管闭塞联合ESD可能是治疗MD患者频繁眩晕发作的有效治疗选择。这种联合疗法有可能成为MD治疗框架的重要补充。
    UNASSIGNED: Meniere\'s disease (MD) is characterized by idiopathic endolymphatic hydrops (ELH). Frequent vertigo attacks is the most disabling symptom of MD.
    UNASSIGNED: This study evaluated the efficacy of triple semicircular canal occlusion combined with endolymphatic sac decompression in the treatment of frequent vertigo in patients with MD.
    UNASSIGNED: Eleven patients with complete medical records were included in this study conducted from May 2021 to April 2022. All patients were enrolled to undergo triple semicircular canal occlusion (TSCO) with endolymphatic sac decompression (ESD). Various tests including pure tone audiometry (PTA), vestibular evoked myogenic potentials (VEMPs), the video head impulse test (v-HIT), caloric test data, the Dizziness Handicap Inventory (DHI), the Berg Balance Scale (BBS), and the Tinnitus Handicap Inventory (THI) were performed both before and after the surgery.
    UNASSIGNED: The successful control rate of vertigo was 100% (9/9) in the average 23-month postoperative follow-up period, with complete control rate of 88.89% (8/9) and substantial control rate of 11.11% (1/9).
    UNASSIGNED: Triple semicircular canal occlusion combined with ESD may be an effective treatment option for managing frequent vertigo attacks in patients with MD. This combination therapy has the potential to become a significant addition to the treatment framework for MD.
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  • 文章类型: Journal Article
    UNASSIGNED:探讨通过鼓室导管插入术(TAC)地塞米松治疗难治性梅尼埃病(MD)的长期疗效和安全性。
    未经评估:在此回顾性分析中,从2020年1月至2020年8月在我院接受TAC治疗的60例单侧难治性MD患者随访2年。50例接受内淋巴囊减压(ESD)的患者和50例接受鼓室类固醇(ITS)的患者被确定为对照组。眩晕控制,听力水平,耳鸣,在研究期间评估了听觉丰满度和功能水平。
    UNASSIGNED:经过2年随访,TAC治疗的难治性MD患者的有效眩晕控制率为76.7%(46/60),完全控制率为58.3%(35/60),实质性控制率为18.3%(11/60)。TAC的眩晕控制率与ESD相当(χ2=0.313,p>0.05),且显著高于ITS(χ2=4.380,p<0.05)。这些患者的听力损失率为10.8%(4/37),与对照组无显著差异(χ2=2.452,p>0.05)。TAC患者耳鸣改善率为56.7%(34/60),明显高于ESD(χ2=11.962,p<0.001)和ITS(χ2=15.278,p<0.001)。TAC组的听觉饱满度改善率为56.7%(34/60),显著高于ESD组(χ2=11.962,p<0.001)和ITS组(χ2=5.635,p<0.05)。TAC组功能水平改善率为71.7%(43/60),远高于ITS组(χ2=17.256,p<0.001),但TAC和ESD之间没有显着差异(χ2=0.410,p>0.05)。TAC治疗后无患者出现并发症或不良反应。
    UNASSIGNED:通过TAC治疗地塞米松可有效控制眩晕发作并改善难治性MD患者的相关症状,为MD的治疗提供有价值的新见解。
    UNASSIGNED: To explore the long-term efficacy and safety of dexamethasone treatment via tympanic antrum catheterization (TAC) in intractable Meniere\'s disease (MD).
    UNASSIGNED: In this retrospective analysis, 60 unilateral intractable MD patients treated with TAC in our hospital from January 2020 to August 2020 were followed for 2 years. Fifty patients who underwent endolymphatic sac decompression (ESD) and 50 patients who accepted intratympanic steroids (ITS) were established as the control groups. Vertigo control, hearing level, tinnitus, aural fullness and functional level were assessed during the study.
    UNASSIGNED: The effective vertigo control rate of intractable MD patients with TAC treatment was 76.7% (46/60) after 2 years follow-up, with a complete control rate of 58.3% (35/60) and a substantial control rate of 18.3% (11/60). The vertigo control rate of TAC was comparable to that of ESD (χ 2 = 0.313, p > 0.05), and significantly higher than that of ITS (χ 2 = 4.380, p < 0.05). The hearing loss rate of these patients was 10.8% (4/37), which was not significantly different from the control groups (χ 2 = 2.452, p > 0.05). The tinnitus improvement rate of patients with TAC was 56.7% (34/60), which was significantly higher than that of patients with ESD (χ 2 =11.962, p < 0.001) and ITS (χ 2 =15.278, p < 0.001). The aural fullness improvement rate in the TAC group was 56.7% (34/60), which was significantly higher than that in the ESD (χ 2 = 11.962, p < 0.001) and ITS groups (χ 2 = 5.635, p < 0.05). The functional level improvement rate in the TAC group was 71.7% (43/60), which was much higher than that in the ITS group (χ 2 = 17.256, p < 0.001), but there was no significant difference between TAC and ESD (χ 2 = 0.410, p > 0.05). No patients had complications or adverse reactions following TAC treatment.
    UNASSIGNED: Dexamethasone treatment via TAC can effectively control vertigo attacks and improve related symptoms of intractable MD patients, providing valuable new insights into the treatment of MD.
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  • 文章类型: Comparative Study
    Background: TSCP has shown its efficacy in vertigo control for intractable Meniere\'s disease. However, hearing impairment remains a problem and hampered the application of the surgery.Aims/objectives: To investigate the effect of dexamethasone on the hearing of Meniere\'s disease patients after TSCP to determine whether inflammation is involved in this processMaterial and methods: Meniere\'s disease patients who received TSCP surgeries were treated with or without dexamethasone postoperatively. All patients\' hearing function were evaluated during a follow up of 2 years after surgery and compared between the two groups.Results: Hearing worsening and word recognition score loss were milder in the dexamethasone group than in the non-dexamethasone group. The rates of profound hearing worsening and word recognition score loss remained significantly lower in the dexamethasone group than in the non-dexamethasone group even 2 years after surgery.Conclusions: Dexamethasone protects the hearing of Meniere\'s patients after TSCP. Inflammation may be involved in the mechanism by which TSCP causes hearing impairment in these patients.Significance: This finding suggests that steroids should be used routinely after TSCP for hearing preservation, and operative precedures need to be modified to minimize inflammation in the inner ear.
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  • 文章类型: Journal Article
    Meniere\'s disease is a common chronic inner ear disease. Because the definitive pathogenesis is still unknown, there is currently no cure for this disorder. Semicircular canal plugging (SCP), first used to treat patients with intractable benign paroxysmal positional vertigo, has since been applied to patients with intractable peripheral vertigo. This study was aimed to explore the long-term efficacy of triple semicircular canal plugging (TSCP) in the treatment of intractable Meniere\'s disease (MD) so as to provide a new method in the framework of treatment with MD.
    Three hundred and sixty-one unilateral MD patients, who were treated with TSCP in our hospital between Dec. 2010 and Sep. 2016, were recruited in this study for retrospective analysis. Vertigo control and auditory function were monitored during a period of two-year follow-up. Seventy three patients who were subjected to intratympanic gentamicin were selected as a control group. Pure tone audiometry, caloric test, vestibular evoked myogenic potential (VEMP) were performed in two-year follow-up.
    The total control rate of vertigo in TSCP group was 97.8% (353/361) in the two-year follow-up, with complete control rate of 80.3% (290/361) and substantial control rate of 17.5% (63/361). The rate of hearing loss was 26.3% (95/361). The total control rate of vertigo in intratympanic gentamicin group was 83.6% (61/73), with complete control rate of 63.0% (46/73) and substantial control rate of 20.5% (15/73). The rate of hearing loss was 24.7% (18/73). The vertigo control rate of TSCP was significantly higher than that of chemical labyrinthectomy(χ2 = 24.798, p <  0.05). There was no significant difference of hearing loss rate between two groups. (χ2 = 0.087, p >  0.05).
    Triple semicircular canal plugging (TSCP), which can reduce vertiginous symptoms in patients with intractable Meniere\'s disease (MD), represents an effective therapy for this disorder. It might become a new important method in the framework of treatment with MD.
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  • 文章类型: Journal Article
    CONCLUSIONS: TSCP, which can reduce vertiginous symptoms in patients with intractable MD, represents an effective therapy for this disorder.
    OBJECTIVE: To explore the long-term efficacy of triple semicircular canal plugging (TSCP) in the treatment of intractable Meniere\'s disease (MD).
    METHODS: Seventy-nine patients diagnosed with unilateral MD referred to a vertigo clinic of the hospital between December 2010 and December 2013 were included in this study for retrospective analysis. TSCP was performed in the affected ear for each patient. Vertigo control and auditory function were measured. Pure tone audiometry, caloric test, and cervical vestibular evoked myogenic potential (cVEMP) were performed in 2-year follow-up. Thirty-six MD patients, who accepted endolymphatic sac decompression (ESD) operation were selected as a comparison group.
    RESULTS: The total control rate of vertigo in the TSCP group was 98.7% in the 2-year follow-up, with a complete control rate of 81.0% and substantial control rate of 17.7%. The rate of hearing preservation was 70.9%. The total control rate of vertigo in the ESD operation group was 72.2%. The vertigo control rate of TSCP was significantly higher than that of ESD operation. Twenty-four months after treatment, canal paresis was found in the operation side of all patients of TSCP by means of caloric test.
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