Stickler syndrome is a genetic disorder characterized by collagen abnormalities leading to various ocular manifestations, such as retinal detachment. We present two cases of siblings clinically diagnosed with Stickler syndrome who exhibited retinal detachment. Case 1, a seven-year-old girl, and case 2, her 14-year-old brother, both displayed severe myopia and other clinical signs consistent with Stickler syndrome. Despite their ages, neither case showed evidence of posterior precortical vitreous pocket (PPVP) on imaging or during surgical intervention. These findings suggest a potential relationship between collagen abnormalities and PPVP dysplasia in Stickler syndrome.

UNASSIGNED: High-resolution Ultrasound (USG) provides good anatomical details of the ocular posterior segment and depicts the various pathological conditions affecting the ocular posterior segment, which helps ophthalmologists for choosing the best treatment options. This study aims to evaluate the utility of High-resolution Ultrasonography in the Evaluation of Posterior Segment Ocular lesions by using Sensitivity and Specificity.
UNASSIGNED: A hospital-based retrospective study enrolled 81 patients in a tertiary care hospital. Clinical and ophthalmological examinations were performed followed by USG of the orbits. B-mode USG was done with a 7.5-13 MHz linear probe. The final diagnosis was made by correlating the USG findings with clinical and ophthalmological examinations.
UNASSIGNED: Sensitivity, specificity, the positive predictive value, the negative predictive value, and the accuracy of B-scan USG were compared with the ophthalmological findings by using the Chi-square test.
UNASSIGNED: Of 81 patients (n=48 males and n=33 females) with a mean age of 38.98 ± 16.48 [SD] years, posterior segment ocular lesions in association with cataracts were found in 27 (33.3%) patients, whereas 14 (51.9%) patients had posterior vitreous detachment (PVD), 10 (37%) patients had retinal detachment (RD), and 1 (3.7%) patient had choroidal detachment (CD). Posterior segment ocular pathologies were found in 17 (21%) patients with blunt ocular injuries, whereas 8 (47.1%) patients had PVD, 4 (23.5%) patients had RD and 4 (23.5%) patients had CD. The ocular USG had a sensitivity of 87.32%, specificity of 80%, and accuracy of 86.42% with a statistically significant difference between the USG findings and the Ophthalmology diagnosis of the posterior segment ocular abnormalities of a p-value of 0.0005.
UNASSIGNED: High-resolution ultrasound is one of the best and an easily available imaging modality for the evaluation of posterior segment ocular pathologies, especially in the presence of opaque ocular media.
UNASSIGNED: Aukštos raiškos ultragarsas (trumpinama USG) suteikia kokybišką ir detalią anatominę informaciją apie užpakalinį akies segmentą bei parodo įvairias patologines būkles, paveikiančias užpakalinį akies segmentą. Tai teikia galimybę oftalmologams pasirinkti geriausią gydymo variantą. Šiuo tyrimu siekiama įvertinti, kiek naudingas aukštos raiškos ultragarsas, vertinant užpakalinio akies segmento pažeidimus, ir kaip tai atspindi jautrumas ir specifiškumas.
UNASSIGNED: Ligoninėje (tretinio lygmens medicinos įstaigoje) atliktas perspektyvusis tyrimas, kuriame dalyvavo 81 pacientas. Atlikti klinikiniai ir oftalmologiniai akiᶙ tyrimai, po kuriᶙ buvo atliekamas akiduobės USG. B režimo USG buvo atliktas su 7,5–13 MHz linijiniu zondu. Galutinė diagnozė pateikta susiejant ultragarso duomenis su klinikiniais ir oftalmologiniais tyrimais.
UNASSIGNED: Jautrumas, specifiškumas, teigiama nuspėjamoji vertė, neigiama nuspėjamoji vertė ir B režimo USG buvo lyginami su oftalmologiniᶙ tyrimᶙ išvadomis pasitelkiant chi kvadrato testą.
UNASSIGNED: Iš 81 paciento (n = 48 vyrai ir n = 33 moterys), kuriᶙ vidutinis amžius 38,98 ± 16,48 [SD] metai, užpakalinio akies segmento pažeidimai, susiję su katarakta, buvo nustatyti 27 (33,3 %) pacientams, o 14 (51,9 %) pacientᶙ nustatyta užpakalinė stiklakūnio atšoka (trumpinama PVD), 10 (37 %) pacientᶙ buvo tinklainės atšoka (trumpinama RD), o 1 (3,7 %) pacientui nustatyta choroidinė atšoka (trumpinama CD). Užpakalinio akiᶙ segmento patologija nustatyta 17 (21 %) pacientᶙ, kurie buvo patyrę akiᶙ pažeidimus neaštriu daiktu, o 8 pacientams (47,1 %) nustatytas PVD, 4 (23,5 %) pacientams RD bei 4 pacientams (23,5 %) buvo CD. Akiᶙ USG jautrumas 87,32 %, specifiškumas siekė 80 %, o tikslumas buvo 86,42 %. Nustatytas statistiškai svarbus skirtumas tarp USG rezultatᶙ ir užpakalinio akies segmento anomalijᶙ oftalmologinės diagnozės; nustatyta p vertė 0,0005.
UNASSIGNED: Aukštos raiškos ultragarsas yra vienas iš geriausiᶙ bei lengvai prieinamas raiškaus vaizdavimo modalumas vertinant užpakalinio akies segmento patologijas, ypač kai akyse yra kokiᶙ nors neskaidriᶙ elementᶙ.

Epiretinal membranes (ERMs) typically remain stable or progressively worsen. Here, we report two rare cases of spontaneous ERM regression and one case of ERM separation. This is a case series of three patients. The patients\' clinical data were collected and ERMs were evaluated with serial optical coherence tomographies (OCTs). Cases one and two were female patients presenting with floaters. Mild-to-moderate idiopathic ERM was diagnosed which spontaneously regressed over the following years without intervention and evidence of separation. Patients\' vision was slightly decreased or remained stable, respectively. Case three was a female patient presenting with blurry vision. A mild ERM was diagnosed with vitreomacular traction (VMT) and a tiny macular hole. Over the following three months, ERM separation along with VMT release was evidenced on OCT. The macular hole healed simultaneously. Her vision improved from 20/70 to 20/30. The possibility of spontaneous regression of idiopathic ERMs should be a factor to consider in management. Further research must be done to determine the mechanism of this phenomenon.

Induction of posterior vitreous detachment (PVD) is one of the most critical steps for the success of retinal detachment (RD) surgery. Failure to completely remove the vitreous can result in re-detachments. We describe a novel technique to induce PVD. After core vitrectomy, perfluorocarbon liquid (PFCL) is injected. The vitreous on the posterior pole is gently stroked, with a diamond-dusted membrane scraper, to create a defect in it. This defect is gradually enlarged to create a ring of rolled out vitreous. The entire vitreous is removed in form of a sheet by lifting the edges of the ring using an internal limiting membrane peeling forceps. PFCL naturally slides into the potential space, gradually extending the vitreous detachment peripherally. With this technique, the vitreous sheet in case of RD can easily, effectively and safely be removed with this technique.