Background: Patellofemoral osteoarthritis (PF OA) is exceptionally predominant and limiting. However, little is known about the risk factors that contribute to its onset and progression. Purpose: The aim of this study was to decide if women with PF OA descend stairs using different muscular activation strategies compared to similarly aged healthy controls. Methods: Thirty-one women with isolated PF OA and 11 similarly aged healthy women took part in this study. The activation onset and duration of PF OA in vastus medialis oblique (VMO), vastus lateralis (VL), gluteus medius (GM), transversus abdominis (TrA), and multifidus muscles were evaluated during the stair descent task using surface electromyography (EMG). Results: There was a non-significant difference between women with PF OA and healthy controls regarding all tested variables, except for the GM activation onset that was significantly delayed in women with PF OA, with the p-value of 0.011. Conclusion: The causes of PF OA differ and might not always be due to a lack of quadriceps strength or VMO activation deficiency, and prospective longitudinal studies are required to confirm this assumption.

The purpose of this study was to examine the changes in muscular activity between the left and right lower legs during gait in healthy children throughout temporal parameters of EMG and symmetry index (SI). A total of 17 healthy children (age: 8.06 ± 1.92 years) participated in this study. Five muscles on both legs were examined via the Vicon 8-camera motion analysis system synchronized with a Trigno EMG Wireless system and a Bertec force plate; onset-offset intervals were analyzed. The highest occurrence frequency of the primary activation modality was found in the stance phase. In the swing phase, onset-offset showed only a few meaningful signs of side asymmetry. The knee flexors demonstrated significant differences between the sides (p < 0.05) in terms of onset-offset intervals: biceps femoris in stance, single support, and pre-swing phases, with SI values = -6.45%, -14.29%, and -17.14%, respectively; semitendinosus in single support phase, with SI = -12.90%; lateral gastrocnemius in swing phase, with SI = -13.33%; and medial gastrocnemius in stance and single support phases, with SI = -13.33% and -23.53%, respectively. The study outcomes supply information about intra-subject variability, which is very important in follow-up examinations and comparison with other target groups of children.

The occupant\'s posture can be changeable to an inadvertent or unintentional out-of-seat position (OOSP) depend on their convenience. Understanding for OOSP has been demanded, but it is not sufficient; especially when AEB is activated. The aim of the current study was to characterize the motion responses of an occupant in various OOSPs when AEB is activated and to identify if there were any additional risks of injury or discomfort to the occupant. The normal seat position (NSP) and three OOSPs were defined to compare the difference of human responses, and six healthy males were participated. Particularly, the maximum rotation angles of the neck in OOSP2 and OOSP3 differed significantly around 1.3 ± 0.3 and 1.4 ± 0.2 times higher respectively than from in the NSP (p < 0.05). Occupants assuming OOSP3 exhibited motion characteristics were not restrained effectively and characterized a hovering and falling upper body and a slipping pelvis. This study has identified, for the first time, a potential risk of injury or discomfort when AEB is activated while an occupant is in an OOSP. This study may serve as fundamental data for the development of safety system that can improve restraint and counteract any deterioration in occupant safety.

The tearing of a muscle-tendon complex (MTC) is caused by an eccentric contraction; however, the structures involved and the mechanisms of rupture are not clearly identified. The passive mechanical behavior the MTC has already been modeled and validated with the discrete element method. The muscular activation is the next needed step. The aim of this study is to model the muscle fiber activation and the muscular activation of the MTC to validate their active mechanical behaviors. Each point of the force/length relationship of the MTC (using a parabolic law for the force/length relationship of muscle fibers) is obtained with two steps: 1) a passive tensile (or contractile) test until the desired elongation is reached and 2) fiber activation during a position holding that can be managed thanks to the Discrete Element model. The muscular activation is controlled by the activation of muscle fiber. The global force/length relationship of a single fiber and of the complete MTC during muscular activation is in agreement with literature. The influence of the external shape of the structure and the pennation angle are also investigated. Results show that the different constituents of the MTC (extracellular matrix, tendon), and the geometry, play an important role during the muscular activation and enable to decrease the maximal isometric force of the MTC. Moreover, the maximal isometric force decreases when the pennation angle increases. Further studies will combine muscular activation with a stretching of the MTC, until rupture, in order to numerically reproduce the tearing of the MTC.

In everyday muscle action or exercises, a stretch-shortening cycle (SSC) is performed under different levels of intensity. Thereby, compared to a pure shortening contraction, the shortening phase in a SSC shows increased force, work, and power. One mechanism to explain this performance enhancement in the SSC shortening phase is, besides others, referred to the phenomenon of stretch-induced increase in muscle force (known as residual force enhancement; rFE). It is unclear to what extent the intensity of muscle action influences the contribution of rFE to the SSC performance enhancement. Therefore, we examined the knee torque, knee kinematics, m. vastus lateralis fascicle length, and pennation angle changes of 30 healthy adults during isometric, shortening (CON) and stretch-shortening (SSC) conditions of the quadriceps femoris. We conducted maximal voluntary contractions (MVC) and submaximal electrically stimulated contractions at 20%, 35%, and 50% of MVC. Isometric trials were performed at 20° knee flexion (straight leg: 0°), and dynamic trials followed dynamometer-driven ramp profiles of 80°-20° (CON) and 20°-80°-20° (SSC), at an angular velocity set to 60°/s. Joint mechanical work during shortening was significantly (p < 0.05) enhanced by up to 21% for all SSC conditions compared to pure CON contractions at the same intensity. Regarding the steady-state torque after the dynamic phase, we found significant torque depression for all submaximal SSCs compared to the isometric reference contractions. There was no difference in the steady-state torque after the shortening phases between CON and SSC conditions at all submaximal intensities, indicating no stretch-induced rFE that persisted throughout the shortening. In contrast, during MVC efforts, the steady-state torque after SSC was significantly less depressed compared to the steady-state torque after the CON condition (p = 0.034), without significant differences in the m. vastus lateralis fascicle length and pennation angle. From these results, we concluded that the contribution of the potential enhancing factors in SSCs of the m. quadriceps femoris is dependent on the contraction intensity and the type of activation.

Spastic impaired limb function is a frequent result of brain lesions. Although its assessment is important for clinical and therapeutical management, it still lacks an objective measure to quantify the functionality of the affected limb. The present paper reports a procedure based on the muscular activation recorded by Surface Electromyography (sEMG), which enables the assessment of the degree of spastic impairment. 15 healthy subjects and 7 patients with impaired upper limb function due to spasticity were included in the study. SEMG was recorded from the biceps and brachioradialis during active elbow extension at different movement velocities. The spastic impairment was clinically assessed by the Tardieu-Test and the Wolf Motor Function Test. Results of the clinical assessment and parameter values quantifying the muscular activation at different joint positions and movement velocities have been set in relation to one another. The results show that spastic impairment leads to a changed correlation between the muscular activation and movement velocity as well as to a changed inter-muscular co-ordination of biceps and brachioradialis. These changes, reflected in the sEMG, can be quantified by 5 newly introduced parameters. This way could allow the assessment of spastic impairment in the context of functional everyday tasks, for the first-time.

How do synergistic muscles interact, when their contraction aims at stabilizing and fine-tuning a movement, which is induced by the antagonistic muscle? The aim of the study was to analyze the interaction of biceps and brachioradialis during fine-tuning control tasks in comparison to load bearing ones. The surface electromyogram of biceps, brachioradialis and triceps were examined in 15 healthy subjects in dynamic flexion and extension movements with different combinations of contraction levels, joint angles and angular velocities. The measurements were conducted in two configurations, where the torque due to an external load opposes the rotational direction of the elbow flexion (load bearing tasks) or the elbow extension (fine-tuning tasks). Whereas during load bearing control tasks, similar muscular activation of biceps and brachioradialis was observed for all joint angles, angular velocities and external loads, during fine-tuning control tasks a significant difference of the muscular activation of both flexors was observed for 1kg, F(3.639,47.305)=2.864, p=0.037, and 5kg of external load, F(1.570,21.976)=6.834, p=0.008. The results confirm the synergistic muscular activation of both flexors during load bearing tasks, but suggest different control strategies for both flexors when they comprise a fine-tuning control task.

OBJECTIVE: There is some evidence that muscular activation during exercise is enhanced by higher levels of blood flow restriction (BFR). However, the impact of different relative levels of BFR on the acute neuromuscular response to resistance exercise is not yet fully understood. We examined the acute effects of low-intensity knee extensions [20 % of 1-repetition maximum (1RM)] with BFR on muscle activation, neuromuscular fatigue and torque in the rectus femoris (RF) and vastus medialis (VM) muscles.
METHODS: Fourteen men (24.8 ± 5.4 years) exercised at 20 % 1RM combined with 40, 60 and 80 % BFR. Restrictive pressures were calculated based on direct blood-flow measurements taken at rest on each participant. Torque was determined during pre- and post-exercise maximal voluntary contractions. Surface electromyographic activity [root mean square (RMS)] was obtained during dynamic and sustained isometric contractions before and after exercise. The median frequency (MF) of the electromyographic power spectrum was computed for isometric contractions.
RESULTS: Torque only decreased in the 80 % BFR condition (-5.2 %; p < 0.01). Except for the VM in the 40 % BFR, MF decreased in both muscles post-exercise in all conditions (p < 0.01). MF decrements were of greater magnitude post-exercise at higher levels of BFR. RMS increased within all sets in both muscles (p < 0.01) and attained higher values in the 80 % BFR condition; except for set 1 in the RF muscle (p < 0.01).
CONCLUSIONS: Muscular activation, as well as neuromuscular fatigue, varies as a function of relative BFR intensity. Therefore, the individual determination of vascular restriction levels is crucial before engaging in BFR exercise.

BACKGROUND: The sit-to-stand movement requires balance control and coordination between the trunk and lower limbs. For these reasons, it is commonly used in clinics for evaluating lower limb muscle function in the elderly. The aim of the present study was to point out re levant biomechanical and neurophysiological sit-to-stand parameters allowing comparison between elderly fallers and non-fallers.
METHODS: Ten elderly fallers and thirty non-fallers performed sit-to-stand movements. Sit-to-stand mechanical (maximal and mean force, impulse) and temporal parameters were measured in the vertical and anteroposterior axes using force platforms. Activity of rectus femoris, vastus lateralis, and gastrocnemius lateralis muscles was bilaterally recorded by surface electromyography.
RESULTS: Time to realize sit-to-stand movements was significantly longer in elderly fallers compared to non-fallers (p < 0.05). In the same way, maximal vertical force and mean posterior force applied on force platform were significantly lower (p < 0.05) in fallers than in non-fallers individual. At muscular activity level, results showed a main statistical difference in gastrocnemius lateralis muscle activity patterns between faller and non-faller groups.
CONCLUSIONS: Vertical and anteroposterior data from force platform, and gastrocnemius lateralis muscle activity determined during sit-to-stand movement are the most relevant parameters to differentiate fallers and non-fallers. Moreover, these factors highlight different strategies to rise from a chair between faller and non-faller group, suggesting that fallers would constantly adjust their control balance during the sit-to-stand movement.

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