endovascular treatment

血管内治疗
  • 文章类型: Case Reports
    1型神经纤维瘤病(NF-1)的特征通常是与血管易损性相关的血管疾病,可导致不利的结果。这里,我们描述了1例NF-1合并大量皮下血肿的病例,存在视力损害的风险,因此快速减压和随后的侵入性较小的方法可获得良好的结果.
    一名患有NF-1的40岁女性患者在轻度头部挫伤后出现巨大的左皮下颞部血肿。住院四天后,血肿增大,严重压迫左眼,提示立即清除血肿以保持视觉功能。血肿清除后立即,在数字减影血管造影中发现了颞浅动静脉瘘,并通过血管内手术栓塞。她的视力得以保留,随访期间未见出血复发.
    手术血肿清除后血管内治疗可有效保留视功能。由于血管脆性是NF-1患者的特征,因此应记住血管并发症可能导致严重的临床结果。在某些NF-1病例中,血管异常的微创治疗可能是优选的。
    UNASSIGNED: Neurofibromatosis type 1 (NF-1) is often characterized by vascular disorders related to vessel vulnerability that can lead to unfavorable outcomes. Here, we describe a case of NF-1 complicated with a massive subcutaneous hematoma posing a risk of visual impairment for which rapid decompression and a subsequent less invasive approach result in a favorable outcome.
    UNASSIGNED: A 40-year-old woman with NF-1 presented with a massive left subcutaneous temporal hematoma following a mild head contusion. Four days after hospitalization, the hematoma increased in size and severely compressed the left eye, prompting immediate hematoma removal to preserve visual function. Immediately after the hematoma removal, a superficial temporal arteriovenous fistula was found on the digital subtraction angiography and embolized by the endovascular procedure. Her visual acuity was preserved, and no bleeding recurrence was observed throughout the follow-up.
    UNASSIGNED: Surgical hematoma removal followed by endovascular treatment was effective in preserving visual function. Since vessel fragility is characteristic of patients with NF-1, it should be kept in mind that vascular complications may lead to serious clinical outcomes. In certain NF-1 cases, less invasive treatments for vascular abnormalities may be preferable.
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  • 文章类型: Journal Article
    背景:胸廓内动脉瘤(ITAA)是一种极为罕见的疾病,报告的病例中约有三分之二是医源性假性动脉瘤。其余的归因于各种原因,包括血管炎,结缔组织病,和1型神经纤维瘤病(NF-1)。NF-1是一种常染色体显性遗传性疾病,其特征在于独特的临床表现,偶尔包括危及生命的血管并发症。尽管NF-1患者可能会出现各种血管异常,ITAA破裂的报道很少,只有7个案例。
    方法:一名患有NF-1的32岁男性因持续的左背部和上臂疼痛而咨询了3天的病史。初次胸片提示左侧胸腔积液,左肺尖部混浊。计算机断层扫描显示左上纵隔有肿块,最初被怀疑是肿瘤。随后的对比增强计算机断层扫描显示肿块为锁骨下动脉瘤。详细的对比增强计算机断层扫描与1-mm切片进行手术计划,确定肿块为左侧ITAA,包含破裂。考虑到再次破裂的风险,进行了紧急血管造影,证实左ITAA破裂无外渗。在近端和远端用多个微线圈成功地治疗了ITAA。患者恢复顺利,并在术后第四天出院。
    结论:该病例强调了在存在胸腔积液的NF-1患者中考虑血管病变的重要性。它还强调了诊断ITAA的挑战以及薄层对比增强计算机断层扫描和血管内治疗的有效性。
    BACKGROUND: An internal thoracic artery aneurysm (ITAA) is an exceedingly rare condition, with approximately two-thirds of reported cases being iatrogenic pseudoaneurysms. The remainder are attributed to various causes, including vasculitis, connective tissue disease, and neurofibromatosis type 1 (NF-1). NF-1 is an autosomal dominant disorder characterized by distinct clinical manifestations that occasionally include life-threatening vascular complications. Although NF-1 patients may develop various vascular abnormalities, ruptured ITAA is rarely reported, with only seven published cases.
    METHODS: A 32-year-old man with NF-1 consulted for a three-day history of persistent left back and upper arm pain. Initial chest radiography indicated left pleural effusion and an opacity at the left lung apex. Computed tomography scan revealed a mass in the left upper mediastinum that was initially suspected to be a tumor. Subsequent contrast-enhanced computed tomography revealed the mass to be a subclavian artery aneurysm. Detailed contrast-enhanced computed tomography with 1-mm slices was performed for surgical planning, identifying the mass as a left ITAA with contained rupture. Given the risk of re-rupture, emergency angiography was performed, which confirmed rupture of the left ITAA without extravasation. The ITAA was successfully treated with multiple microcoils at the proximal and distal ends. The patient had an uneventful recovery and was discharged on the fourth postoperative day.
    CONCLUSIONS: This case highlights the importance of considering vascular lesions in NF-1 patients who present with pleural effusion. It also emphasizes the challenges in diagnosing ITAA and the effectiveness of thin-slice contrast-enhanced computed tomography scans and endovascular treatment.
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  • 文章类型: Journal Article
    目的在神经血管内治疗中,有很多机会引导多个导管进入颅内血管。我们根据体外实验研究的指导顺序报告了两个微导管之间的关系。材料和方法我们假设在弯曲的血管中,例如颈内动脉的突突旁区域,最初被引导的导管倾向于穿过内部,后来被引导的导管倾向于通过外部。在硅胶血管动脉瘤模型中使用微导管和球囊导管进行体外验证。结果,发现两个导管是根据我们的假设排列的。在球囊辅助线圈栓塞的实际操作中也观察到了这一发现。结论两种导管根据导航顺序的位置关系非常重要,特别是在球囊辅助盘绕和支架辅助盘绕期间通过监禁的微导管。
    Objective  In neuroendovascular treatment, there are many opportunities to guide multiple catheters into the intracranial blood vessels. We report the relationship between two microcatheters according to the guiding order with experimental in vitro studies. Materials and Methods  We hypothesize that in a bent blood vessel such as a paraclinoid region of the internal carotid artery, the catheter that was first guided tended to pass through the inside, and the catheter that was guided later tended to pass through the outside. The in vitro verification was performed using a microcatheter and a balloon catheter in a silicone vascular aneurysmal model. Results  As a result, it was found that the two catheters were arranged according to our hypothesis. This finding was also observed during the actual operation of balloon-assisted coil embolization. Conclusion  The positional relationship between the two catheters according to the navigation order is very important, in particular during balloon-assisted coiling and stent-assisted coiling via a jailed microcatheter.
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  • 文章类型: Journal Article
    胰十二指肠切除术(PD)是一种复杂的外科手术,适用于胰头壶腹周围肿瘤患者。Vater的乳头,胆总管远端,还有十二指肠.在晚期肿瘤中,手术技术包括需要解剖和剥离位于胰十二指肠区域内的动脉,包括肝总动脉(CHA)和肝固有动脉(PHA)及其分支。PD后内脏动脉瘤的第二重要原因是术后胰瘘(POPF)中胰液对胰周动脉壁的刺激。肝动脉假性动脉瘤(HAP)是一种非常危险的疾病,因为它通常是无症状的,但它是一种罕见且可能致命的病理,因为它破裂的风险很高。因此,HAP需要治疗。目前,选择性腹腔血管造影是PD患者术后出血和假性动脉瘤诊断和治疗的金标准.对HAP患者进行开放手术和微创血管内治疗。血管内治疗包括经动脉栓塞(TAE)和支架移植物植入。治疗方法的选择取决于一般情况和当地情况,如患者的血流动力学稳定性和动脉解剖。在保留肝动脉血流的患者中(为了防止肝缺血并发症,例如肝梗塞,脓肿,或失败)是需要的,支架移植物植入是治疗的选择。本文就血管内治疗HAP的两种常用方法作一综述。此外,已经描述了风险因素和诊断工具。
    Pancreaticoduodenectomy (PD) is a complex surgical procedure performed in patients with periampullary tumors located within the pancreatic head, the papilla of Vater, the distal common bile duct, and the duodenum. In advanced tumors, the operative technique involves the need for dissection and divestment of the arteries located within the pancreaticoduodenal field, including the common hepatic artery (CHA) and the proper hepatic artery (PHA) and its branches. The second most important cause of post-PD visceral aneurysms is irritation of the peri-pancreatic arterial wall by pancreatic juice in a postoperative pancreatic fistula (POPF). Hepatic artery pseudoaneurysm (HAP) is a very dangerous condition because it is usually asymptomatic, but it is a rare and potentially lethal pathology because of the high risk of its rupture. Therefore, HAP requires treatment. Currently, selective celiac angiography is the gold-standard diagnostic and therapeutic management for postoperative bleeding and pseudoaneurysm in patients following PD. Open surgery and less invasive endovascular treatment are performed in patients with HAP. Endovascular treatment involves transarterial embolization (TAE) and stent graft implantation. The choice of treatment method depends on the general and local conditions, such as the patient\'s hemodynamic stability and arterial anatomy. In patients in whom preservation of the flow within the hepatic artery (to prevent hepatic ischemia complications such as liver infarction, abscess, or failure) is needed, stent graft implantation is the treatment of choice. This article focuses on a review of two common methods for endovascular HAP treatment. In addition, risk factors and diagnostic tools have been described.
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  • 文章类型: Journal Article
    背景:与老年患者相比,破裂和未破裂的动脉瘤在年轻人中较少见。在普通人群中,血管内治疗在手术选择上越来越受欢迎,但手术仍是年轻患者的主要治疗方法,因为人们担心血管内手术复发率较高.方法:这项研究比较了40岁以下患者与41-60岁患者的血管内治疗的近期和长期结果。这项研究纳入了239例颅内动脉瘤血管内治疗患者,分为两个年龄组:40岁以下和41-60岁。立即放射学结果的比率,并发症,并评估复发情况。结果:结果显示,年轻组成功的动脉瘤闭塞率为70.1%,老年组为64.0%。年轻组并发症发生率为1.5%,老年组并发症发生率为3.5%,老年组经历更多的手术相关并发症,尽管这种差异没有统计学意义。长期随访显示,年轻组的复发率为23.2%,老年组的复发率为18.2%。没有显著差异。结论:这项研究表明,血管内治疗对40岁以下的患者同样有效和安全。因此,它可能被认为是年轻患者可接受的一线治疗,将其使用与老年人群的使用保持一致。
    Background: Ruptured and unruptured aneurysms are less common in younger individuals compared to older patients. Endovascular treatment has gained popularity over surgical options in the general population, but surgery remains the primary treatment for younger patients due to concerns about higher recurrence rates with endovascular procedures. Methods: This study compared the immediate and long-term outcomes of endovascular treatment in patients under 40 years with those aged 41-60. The study included 239 patients who underwent endovascular treatment for intracranial aneurysms, divided into two age groups: under 40 and 41-60 years. The rates of immediate radiologic outcomes, complications, and recurrence were assessed. Results: The results showed successful aneurysm obliteration rates of 70.1% in the younger group and 64.0% in the older group. The complication rates were 1.5% in the younger group and 3.5% in the older group, with the older group experiencing more procedure-related complications, though this difference was not statistically significant. Long-term follow-up revealed recurrence rates of 23.2% in the younger group and 18.2% in the older group, with no significant difference. Conclusions: The study suggests that endovascular treatment is as effective and safe for patients under 40 years. Therefore, it may be considered an acceptable first-line treatment for younger patients, aligning its use with that in older populations.
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  • 文章类型: Journal Article
    脉络膜前动脉(AChA)动脉瘤的治疗通常与缺血性并发症有关。本研究旨在报告我院未破裂AChA动脉瘤的治疗结果。
    在2015年1月至2022年3月之间,有40例患者在我们医院接受了未破裂的AChA动脉瘤治疗。年龄,性别,动脉瘤大小,AChA分支类型,治疗,闭塞率,并发症,术前和术后90天改良Rankin量表(mRS)评分,和复发进行了调查。分支类型分类为颈内动脉(ICA),脖子,或基于AChA原点位置的圆顶类型。
    平均年龄为61.1±1.9岁;15例患者为男性,25例患者为女性。平均动脉瘤直径为4.4±0.3mm。四名患者的分支类型为ICA,脖子在35,圆顶在一个。治疗方法为手术夹闭22例,血管内线圈栓塞18例(支架辅助14例)。夹闭组所有患者和卷取组9例患者均采用运动诱发电位(MEP)监测。8例(20%)患者出现治疗并发症。4名患者(10%)在治疗后90天mRS评分恶化超过1分;然而,出现这种情况的患者比例在剪裁组和卷绕组之间没有显著差异.虽然血栓形成并发症的几率比夹闭高,差异不显著(比值比:10.2;P=0.08).卷取组的完全闭塞率较低(72.2%vs.95.3%),但差异不显著。中位随访时间为696天(范围:99-2053)。无动脉瘤复发或破裂发生。
    AChA分支类型对于AChA动脉瘤患者的治疗决策很重要。在AChA动脉瘤的夹闭和卷绕之间,并发症和闭塞的发生率没有显着差异。MEP监测可能有助于预防线圈栓塞期间的血栓并发症。
    UNASSIGNED: Treatment of anterior choroidal artery (AChA) aneurysms is frequently associated with ischemic complications. This study aimed to report the outcomes of treatment of unruptured AChA aneurysms in our hospital.
    UNASSIGNED: Between January 2015 and March 2022, 40 patients were treated for an unruptured AChA aneurysm in our hospital. Age, sex, aneurysm size, AChA branching type, treatment, occlusion rate, complications, modified Rankin Scale (mRS) score before surgery and after 90 days, and recurrence were investigated. The branching type was classified as internal carotid artery (ICA), neck, or dome type based on the location of the AChA origin.
    UNASSIGNED: The mean age was 61.1 ± 1.9 years; 15 patients were men and 25 were women. The mean aneurysm diameter was 4.4 ± 0.3 mm. The branching type was ICA in four patients, neck in 35, and dome in one. Treatment was surgical clipping in 22 patients and endovascular coil embolization in 18 (14 with stent assistance). Motor-evoked potential (MEP) monitoring was used in all patients of the clipping group and 9 cases of the coiling group. Treatment complications occurred in eight patients (20%). mRS score worsened by more than one point 90 days after treatment in four patients (10%); however, the proportion of patients who experienced this did not significantly differ between the clipping and coiling groups. Although the odds of a thrombotic complication were higher with coiling than clipping, the difference was not significant (odds ratio: 10.2; P = 0.08). The rate of complete occlusion was lower in the coiling group (72.2% vs. 95.3%), but the difference was not significant. The median follow-up was 696 days (range: 99-2053). No aneurysm recurrence or rupture occurred.
    UNASSIGNED: AChA branching type is important for treatment decision-making in patients with AChA aneurysms. Rates of complications and occlusion do not significantly differ between clipping and coiling of AChA aneurysms. MEP monitoring may be useful in preventing thrombotic complications during coil embolization.
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  • 文章类型: Case Reports
    在自发性孤立性肠系膜上动脉夹层(SISMAD)的治疗中,没有确定的方法来评估肠系膜缺血和确定血管内介入治疗的最佳时机。一名患有急性腹痛的56岁男性被诊断为SISMAD。通过肠系膜血流储备分数(FFR)评估肠系膜缺血后,FFR为0.72,建议患者保守治疗SISMAD,包括禁食,全胃肠外营养,和抗凝。患者经保守治疗14天后未植入支架,症状缓解。在接下来的5年里,患者未见腹痛复发或SISMAD恶化.可以通过肠系膜FFR评估肠系膜缺血的严重程度。在确认排除与SISMAD动脉瘤扩张或破裂相关的风险后,当FFR超过0.72时,支持保守治疗SISMAD的方法可能确实被认为是实用的.
    There is no definitive approach for assessing mesenteric ischemia and determining the optimal timing for endovascular intervention in the management of spontaneous isolated dissection of the superior mesenteric artery (SISMAD). A 56-year-old male with acute abdominal pain was diagnosed with SISMAD. After evaluating mesenteric ischemia through mesenteric fractional flow reserve (FFR), FFR was 0.72, and the patient was recommended conservative treatment for SISMAD, which involves fasting, total parenteral nutrition, and anticoagulation. The patient\'s syndrome was relieved after conservative treatment for 14 days without stent implantation. Over the next 5 years, no recurrence of abdominal pain or worsening of SISMAD was observed in the patient. Assessing the severity of mesenteric ischemia can be done through mesenteric FFR. Upon confirmation of the exclusion of risks related to dilatation or rupture of SISMAD aneurysm, an approach in favor of conservative management for SISMAD may indeed be considered pragmatic when the FFR exceeds 0.72.
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  • 文章类型: Journal Article
    缺血性脑血管病(ICVD)是一种严重的健康问题,其中脑组织由于脑血管阻塞而遭受缺氧损伤。机械血栓切除术是治疗这些患者的常用方法。然而,局部麻醉(LA)和清醒镇静(CS)在取栓过程中的作用尚不清楚.我们根据90天改良Rankin量表(mRS)评分评估了两种麻醉方案之间是否存在关系。
    在这项研究中,我们进行了一项回顾性观察性研究,以评估在4个综合性卒中中心的ICVD患者机械取栓期间使用LA和CS的效果.患者分为LA组和CS组。在倾向评分匹配(PSM)分析下进行1:1匹配前后进行统计分析。主要结果指标是90天时mRS评分为0-2。次要结果是手术时间,再通率,有症状和无症状的出血率,和手术并发症。
    共有193例患者(LA患者118例,CS患者75例)纳入PSM前的最终分析。1:1PSM后,98名患者-每组49名患者-被纳入研究。LA和CS应用组之间的临床结果没有差异(p=0.543)。比较血管内治疗(EVT)后随访时的血压(BP)值,CS组的最低收缩压和最低舒张压均较低(p=0.001和p=0.009).两组再通率无显著差异,症状性颅内出血(sICH)率,90天mRS,和手术相关并发症发生率(p=0.617,p=0.274,p=0.543,p=1.000)。
    这项研究没有揭示在90天mRS的EVT期间应用CS的优越性,sICH,再通率,或手术并发症。然而,CS应用期间发生低血压的风险较高.
    UNASSIGNED: Ischemic cerebrovascular disease (ICVD) is a serious health problem in which brain tissue suffers from hypoxic damage due to obstruction in cerebral vessels. Mechanical thrombectomy is a commonly used method in the treatment of these patients. However, the effects of local anesthesia (LA) and conscious sedation (CS) during thrombectomy are still unclear. We evaluated whether there was a relationship between the two anesthesia regimens in terms of 90-day modified Rankin Scale (mRS) scores.
    UNASSIGNED: In this study, a retrospective observational study was conducted to evaluate the effects of LA and CS used during mechanical thrombectomy in four comprehensive stroke centers among ICVD patients. Patients were divided into the LA group and the CS group. Statistical analysis was performed before and after 1:1 matching under propensity score matching (PSM) analysis. The primary outcome measure was an mRS score of 0-2 at 90 days. Secondary outcomes were procedure times, recanalization rates, symptomatic and asymptomatic hemorrhage rates, and procedural complications.
    UNASSIGNED: A total of 193 patients (118 patients with LA and 75 patients with CS) were included in the final analysis before PSM. After 1:1 PSM, 98 patients-49 patients from each group-were included in the study. There was no difference in clinical outcomes between the LA- and CS-applied groups (p = 0.543). When blood pressure (BP) values at follow-up after endovascular treatment (EVT) were compared, the lowest systolic and lowest diastolic BP were found to be lower in the CS group (p = 0.001 and p = 0.009). There was no significant difference between the two groups in terms of recanalization rates, symptomatic intracranial hemorrhage (sICH) rates, 90-day mRS, and procedure-related complication rates (p = 0.617, p = 0.274, p = 0.543, and p = 1.000).
    UNASSIGNED: This study did not reveal the superiority of CS applied during EVT on 90-day mRS, sICH, recanalization rates, or procedural complications. However, the risk of developing hypotension during the CS application was found to be high.
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  • 文章类型: Journal Article
    大脑前动脉(ACA)动脉瘤的位置各不相同,在ACA的过程中会出现各种动脉瘤。破裂和一些未破裂的ACA动脉瘤可能需要积极治疗以避免出血或再出血。虽然开放手术是ACA动脉瘤的有效治疗方法,血管内治疗(EVT)正在成为选择病例的替代治疗方法。用于ACA动脉瘤的EVT技术通常有所不同,并且根据动脉瘤的性质和位置逐案进行。为了更好地理解ACA动脉瘤的EVT策略,有必要对ACA动脉瘤进行EVT检查。在这次审查中,讨论了以下主题:ACA解剖和异常,ACA动脉瘤的分类,ACA动脉瘤的自然史,ACA动脉瘤的开放手术和EVT状态,各种ACA动脉瘤的EVT技术,以及EVT治疗ACA动脉瘤的预后和并发症。根据我们的审查和经验,传统的螺旋EVT仍然是大多数ACA动脉瘤的首选治疗方法。对于A1动脉瘤,EVT具有挑战性。在选择合适的案例后,对于ACA动脉瘤患者,采用导流器和WovenEndoBridge装置可获得良好的预后。此外,母体动脉闭塞可用于治疗侧支循环良好的A1动脉瘤和一些远端ACA动脉瘤。总的来说,EVT作为ACA动脉瘤的替代治疗方案越来越受欢迎。
    The locations of anterior cerebral artery (ACA) aneurysms vary, and various aneurysms can occur along the course of the ACA. Ruptured and some unruptured ACA aneurysms may require aggressive treatment to avoid bleeding or rebleeding. Although open surgery is an effective treatment for ACA aneurysms, endovascular treatment (EVT) is becoming an alternative treatment in select cases. EVT techniques for ACA aneurysms often vary and are performed on a case-by-case basis according to the nature and location of the aneurysm. To better understand the EVT strategy for ACA aneurysms, it is necessary to review EVT for ACA aneurysms. In this review, the following topics are discussed: ACA anatomy and anomalies, classifications of ACA aneurysms, the natural history of ACA aneurysms, open surgery and EVT statuses for ACA aneurysms, EVT techniques for various ACA aneurysms, and the prognosis and complications of EVT for ACA aneurysms. According to our review and experience, traditional coiling EVT is still the preferred therapy for most ACA aneurysms. For A1 aneurysms, EVT is challenging. After the selection of appropriate cases, deployment of a flow diverter and Woven EndoBridge device can result in a good prognosis for patients with ACA aneurysms. In addition, parent artery occlusion can be used to treat A1 aneurysms with good collateral circulation and some distal ACA aneurysms. In general, EVT is gaining popularity as an alternative treatment option for ACA aneurysms.
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  • 文章类型: Editorial
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