背景:皮肤肿瘤疾病是男性和女性狗中最常见和第二常见的肿瘤,分别。这项研究的目的是报告2014年至2020年之间位于葡萄牙北部的病理实验室中的犬皮肤肿瘤的发生,并对解剖位置进行表征和分类,品种,年龄,和受不同类型肿瘤影响的动物的性别。
结果:在整个7年的研究中,诊断为皮肤肿瘤1185例,62.9%被归类为良性,37.1%为恶性。肥大细胞瘤(22.7%)是最常见的肿瘤类型,其次是良性软组织肿瘤(9.7%),皮脂腺肿瘤(8.1%),血管肿瘤(7.9%)和软组织肉瘤(7.6%)。皮肤肿瘤通常表现为多中心发生(14.6%),其次是后肢的单一发生(12.1%),前肢(8.6%),臀部(7.1%),腹部(6.5%)和肋部(5.2%)。随着年龄的增长,发生皮肤肿瘤的几率更高(p<0.001)。与男性相比,女性发生皮肤肿瘤的几率增加(粗OR=2.99,95%(2.51,3.55);调整OR=2.93,95%(2.46,3.49)。纯种狗,作为一个群体,与混种狗相比,显示出发生皮肤肿瘤的几率降低(粗OR=0.63,95%(0.53,0.74);调整OR=0.75,95%(0.62,0.89)。
结论:肥大细胞肿瘤,良性软组织肿瘤和皮脂腺肿瘤是最常见的组织学类型。通过这项研究进行的流行病学调查显示了该特定人群中不同类型肿瘤的相对频率。此外,本文获得的结果可以作为当地兽医帮助建立犬皮肤肿瘤组织型的初步和推定诊断的基础或有益参考。皮肤肿瘤是男性和女性狗中最常见和第二常见的肿瘤,分别。这项研究的目的是在位于葡萄牙北部的诊断病理学实验室中报告犬皮肤肿瘤的发生,在2014-2020年之间,为了表征解剖学分布,品种,年龄,和受不同皮肤肿瘤影响的动物的性别。在此期间,1,185例诊断为皮肤肿瘤;62.9%诊断为良性,而37.1%为恶性。肥大细胞瘤(22.7%)是最常见的肿瘤,其次是良性软组织肿瘤(9.7%),皮脂腺肿瘤(8.1%),血管肿瘤(7.9%)和软组织肉瘤(7.6%)。皮肤肿瘤通常发展在一个以上的位置(14.6%),其次是孤立发展在后肢(12.1%),前肢(8.6%),臀部(7.1%),腹部(6.5%)和肋部(5.2%)。随着患者年龄的增加,发现发生皮肤肿瘤的几率增加。与雄性狗相比,雌性狗的几率增加。与混种狗相比,纯种狗患皮肤肿瘤的几率降低。通过这项研究获得的信息相关性证明了该特定人群中不同类型肿瘤的相对频率。在提供犬皮肤肿瘤的初步诊断时,作为区域兽医的基础或有益参考。
BACKGROUND: Cutaneous neoplastic diseases are the most and second-most frequently reported tumors in male and female dogs, respectively. The aims of this study were to report the occurrence of canine cutaneous tumors in a pathology laboratory located in Northern Portugal between 2014 and 2020, and to characterize and categorize the anatomical locations, breed, age, and sex of the animals affected with different types of neoplasms.
RESULTS: Throughout the 7-year study, 1,185 cases were diagnosed as cutaneous tumors, with 62.9% being classified as benign, and 37.1% as malignant. Mast cell tumors (22.7%) were the most frequently diagnosed tumor type, followed by benign soft tissue tumors (9.7%), sebaceous gland tumors (8.1%), vascular tumors (7.9%) and soft tissue sarcomas (7.6%). Cutaneous tumors commonly exhibited multicentric occurrence (14.6%) followed by single occurrence in hindlimb (12.1%), forelimb (8.6%), buttock (7.1%), abdominal (6.5%) and costal (5.2%) areas. The odds of developing cutaneous neoplasia were higher with increasing age (p < 0.001). Females had an increased odds of developing skin tumors compared to males (crude OR = 2.99, 95% (2.51, 3.55); adj OR = 2.93, 95% (2.46, 3.49). Purebred dogs, as a group, showed a reduced odds of developing cutaneous tumors when compared to mixed-breed dogs (crude OR = 0.63, 95% (0.53, 0.74); adj OR = 0.75, 95% (0.62, 0.89).
CONCLUSIONS: Mast cell tumors, benign soft tissue tumors and sebaceous tumors were the most common histotypes encountered. The epidemiological survey achieved with this study demonstrates the relative frequency of different types of tumors in this particular population. Furthermore, the results herein achieved can act as a basis or a beneficial reference for local veterinarians helping in the establishment of a preliminary and presumptive diagnosis of canine cutaneous tumors histotypes. Skin tumors are the most and second-most frequently reported tumors in male and female dogs, respectively. The aim of this study was to report the occurrence of canine skin tumors in a diagnostic pathology laboratory located in Northern Portugal, between 2014-2020 and to characterize the anatomical distributions, breed, age, and sex of the animals affected by different skin tumors. During this period, 1,185 cases were diagnosed as skin tumors; 62.9% were diagnosed as benign, while 37.1% were malignant. Mast cell tumors (22.7%) were the most frequently diagnosed neoplasia, followed by benign soft tissue tumors (9.7%), sebaceous gland tumors (8.1%), vascular tumors (7.9%) and soft tissue sarcomas (7.6%). Skin tumors commonly developed in more than one location (14.6%) followed by solitary development in hindlimb (12.1%), forelimb (8.6%), buttock (7.1%), abdominal (6.5%) and costal (5.2%) areas. An increased odds of developing skin neoplasms as the patient\'s age increase was detected. Females showed an increased odds in comparison to male dogs. Purebred dogs presented decreased odds for developing skin tumors in comparison to mixed-breed dogs. The information relevance achieved with this study demonstrates the relative frequency of different types of tumors in this particular population, acting as a basis or a beneficial reference for regional veterinarians when providing an initial diagnosis of canine skin tumors.