■升主动脉直径的大规模调查,尤其是在亚洲人口中,缺乏。此外,有关高血压(HP)分布的相关证据,二叶主动脉瓣(BAV),马凡氏综合症(MFS)很少。我们旨在研究升主动脉直径在中国这些人群中的分布。
■对接受心脏超声检查的总人数698795人的数据进行回顾性分析。筛选后,647087人被纳入最终分析。在正常人群中,平均升主动脉直径为28.1±3.2mm(女性为27.2±3.1mm,男性29.0±3.1mm(P<0.001)。主动脉内径随年龄增长而逐渐增大(P<0.001)。主动脉扩张的患病率,动脉瘤,HP患者的解剖率为12.83%,2.70%,和4.77%,分别。在有MFS的个人中,相应的比率为43.92%,35.31%,和26.11%。值得注意的是,尽管BAV患者的主动脉扩张(37.00%)和主动脉瘤(16.46%)发生率很高,主动脉夹层的发生率相对较低(0.74%).大多数主动脉夹层发生在主动脉直径小于55mm。然而,在总人口中,主动脉夹层的发生率随着主动脉直径的增加而明显增加,揭示了“主动脉悖论”的存在。
■(i)上升直径随着年龄的增长而增加,男性大于女性;(ii)解释了“主动脉悖论”;(iii)BAV具有高的主动脉扩张率,但主动脉夹层的发病率较低。
UNASSIGNED: Large-scale investigations on ascending aortic diameter, especially in the Asian population, are lacking. Furthermore, relevant evidence regarding the distribution of hypertension (HP), bicuspid aortic valve (BAV), and Marfan syndrome (MFS) is scarce. We aimed to examine the distribution of ascending aortic diameter in these populations in China.
UNASSIGNED: The data of a total number of 698 795 individuals who underwent cardiac ultrasound were subjected to retrospective analysis. After screening, 647 087 individuals were included in the final analysis. In the normal population, the mean ascending aortic diameter was 28.1 ± 3.2 mm (27.2 ± 3.1 mm in women vs. 29.0 ± 3.1 mm in men) (P < 0.001). Aortic diameter increased gradually with age (P < 0.001). The prevalence of aortic dilation, aneurysm, and dissection in individuals with HP was 12.83%, 2.70%, and 4.77%, respectively. In individuals with MFS, the corresponding rates were 43.92%, 35.31%, and 26.11%. Notably, although BAV patients had high incidences of aortic dilation (37.00%) and aortic aneurysm (16.46%), the incidence of aortic dissection was relatively low (0.74%). Most cases of aortic dissection occurred at an aortic diameter of less than 55 mm. However, in the overall population, the incidence of aortic dissection significantly increased with the increase in the aortic diameter, revealing the existence of an \'aortic paradox\'.
UNASSIGNED: (i) The ascending diameter increases with age and is larger in men than in women; (ii) \'Aortic paradox\' is explained; (iii) BAV bears a high rate of aortic dilation, but a low incidence of aortic dissection.