Spinal bifida

  • 文章类型: Case Reports
    目的是描述一例罕见的表现为进行性尿失禁的腰椎膜膜膨出症。脂膜脊膜膨出是一种闭合性脊柱发育不良,通常表现为脂肪瘤状肿块,在臀裂上方有神经缺损。脊髓栓系综合征被定义为由异常低的脊髓圆锥引起的过度脊髓张力引起的症状和体征。末端有一个异常厚的丝附于下部骶骨区。一名19岁男性,无明显病史,过去一年出现腰背痛和尿失禁。在身体检查中,患者的运动强度正常,所有方式的感官测试都完好无损。直肠音正常,并且没有注意到鞍式麻醉。MRI显示腰椎脂肪膜脊膜膨出伴脊髓栓系综合征。患者接受了栓系脐带松解术和脂肪瘤切除术。软组织病理显示纤维血管组织和成熟脂肪组织符合脂肪瘤。大多数脊髓栓系综合征病例与脊髓发育不良有关,一种罕见的儿科综合症.如果及早发现,它可能是可以治疗的,MRI可以帮助准确诊断病情。老年人更容易出现泌尿系统和神经系统疾病。有进行性症状的患者需要进行手术解开。在我们的案例中,唯一的症状是尿失禁,除腰椎椎旁压痛外,神经系统检查正常。
    The objective is to describe a rare case of lumbar lipomyelomeningocele presenting as progressive urinary incontinence. Lipomyelomeningocele is a type of closed spinal dysraphism typically presenting as a lipomatous mass contiguous with a neural defect above the gluteal crease. Tethered cord syndrome is defined as symptoms and signs caused by excessive spinal cord tension from an abnormally low conus medullaris, with an abnormally thick filum terminale attached to the lower sacral region. A 19-year-old male with no remarkable medical history presented with low back pain and urinary incontinence for the past one year. On physical exam patient had normal motor strength, sensory testing to all modalities was intact. The rectal tone was normal, and no saddle anesthesia was noted. MRI lumbar spine revealed lumbar lipomyelomeningocele with associated tethered cord syndrome. The patient underwent tethered cord release surgery with lipoma excision. Pathology of the soft tissue showed fibrovascular tissue and mature adipose tissue consistent with lipoma. The majority of cases of tethered cord syndrome are related to spinal dysraphism, a rare pediatric syndrome. It is potentially treatable if caught early, and MRI can help with an accurate diagnosis of the condition. Older adults are more likely to present with urological and neurological complaints. Surgical un-tethering is indicated in patients with progressive symptoms. In our case, the only presenting symptom was urinary incontinence, and the neurological exam was normal other than lower lumbar paraspinal tenderness.
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  • 文章类型: Journal Article
    Neural tube defects remain a major problem in developing countries, but there are limited comprehensive national reports to date in Ethiopia. Therefore, this study aimed to assess the prevalence of neural tube defects and associated factors in Ethiopia. Electronic databases and other sources were used to retrieve studies. Fifteen out of 862 studies were included in the final analysis. The estimated pooled prevalence of neural tube defects among children in Ethiopia was 63.3 cases per 10 000 children. The pooled prevalence of spinal bifida, anencephaly, and encephalocele was 41.09, 18.90, and 1.07 per 10 000 children, respectively. Previous family history and unplanned pregnancy were risk factors for neural tube defects. Folic acid supplementation during the first trimester of pregnancy was found to be protective. Neural tube defects are widespread in Ethiopia. Hence, fortification of food with folic acid or folic acid supplementation during childbearing age is recommended.
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  • 文章类型: Journal Article
    OBJECTIVE: To evaluate the accuracy of oblique view extended imaging (OVEI) in locating the position of the fetal conus medullaris.
    METHODS: One hundred and twenty-two normal fetuses and five counterparts with spinal bifida received prenatal ultrasound examination. The vertebral body at the terminal of the conus medullaris and the coronal section of over five vertebral bodies were reconstructed using OVEI. Development of the nervous system of normal fetuses was assessed at postnatal day 28. For spinal bifida cases, pathological examination was performed.
    RESULTS: Among 127 fetuses, the conus medullaris was accurately positioned in 120 (94.0%) cases according to OVEI. OVEI failed to locate the conus medullaris in three healthy fetuses due to obesity of the mother and four cases with spinal bifida due to abnormal fetal position. The conus medullaris was located at L3 or above in 115 healthy fetuses. The conus medullaris was positioned below L4 in five fetuses with spinal bifida, including L5 in two, S1 in two, and S3 in one, which was consistent with the findings of pathological examination.
    CONCLUSIONS: OVEI can display the 12th rib, T12, and conus medullaris simultaneously. OVEI is applicable to precisely locate the position of the conus medullaris and useful for prenatal evaluation of spinal bifida.
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