■评估鼻窦乳头状瘤的临床和预后行为。
■在2001年至2016年期间,在三级鼻学实践中对被诊断为鼻窦乳头状瘤的患者进行了回顾。使用病理专用电子病历软件,诊断为鼻腔鼻窦乳头状瘤的患者被确定。确定了该病变的四个亚类:倒置(IP),外生性(EP)嗜酸细胞(OP)和内翻外生性(IPEP)乳头状瘤。
■共有107例患者被确定为独特的鼻腔鼻窦乳头状瘤诊断。其中,大多数患者被诊断为IP(87,81.3%).与IP和EP单独人群相比,共同诊断为IP和EP(IPEP)的患者亚群在临床表现和预后方面是独特的。IP+EP患者(5,4.7%)年龄较大,平均年龄为75.25岁,而45岁(EP)和55.26岁(IP),p<.0001。与33.3%(EP)和4.6%(IP)相比,IP+EP患者更常出现鼻出血(60%)。最后,所有IP+EP患者至少有一次复发,相比之下,33.3%(EP)和28.5%(IP)。
■每种病理亚型的鼻窦乳头状瘤具有独特的临床特征和手术切除后的复发率。诊断为IP+EP的患者亚群往往年龄较大,更有可能出现鼻出血,更有可能复发。需要对该亚群进行进一步的调查和分析。
■4.
UNASSIGNED: To evaluate the clinical and prognostic behaviors of sinonasal papillomas.
UNASSIGNED: Patients diagnosed with sinonasal papilloma were reviewed between 2001 and 2016 at a tertiary rhinology practice. Using pathology-specific electronic medical record software, patients diagnosed with sinonasal papilloma were identified. Four subcategories of this lesion were identified: inverting (IP), exophytic (EP) oncocytic (OP) and inverting + exophytic (IP + EP) papillomas.
UNASSIGNED: A total of 107 patients were identified with unique sinonasal papilloma diagnoses. Of these, the majority were diagnosed with IP (87, 81.3%). The subpopulation of patients co-diagnosed with IP and EP (IP + EP) was unique with respect to clinical presentation and prognosis relative to both the IP and EP alone populations. IP + EP patients (5, 4.7%) were older with an average age of 75.25 years compared to 45 (EP) and 55.26 (IP), p < .0001. IP + EP patients more often presented with epistaxis (60%) compared to 33.3% (EP) and 4.6% (IP). Finally, all IP + EP patients had at least one recurrence of their disease, compared to 33.3% (EP) and 28.5% (IP).
UNASSIGNED: Each histopathologic subtype of sinonasal papilloma has unique clinical characteristics and recurrence rates after surgical resection. The subpopulation of patients diagnosed with IP + EP tends to be older, more likely to present with epistaxis, and more likely to recur. Additional investigation and analysis of this subpopulation is warranted.
UNASSIGNED: 4.