Referrals

转介
  • 文章类型: Journal Article
    本研究的目的是探讨健康服务的不适当转诊率和类型,并评估多层次干预措施对卡塔尔RawdatAl-Khail健康中心不适当转诊率的影响。
    这项研究对2022年7月至2023年8月从电子健康记录(EHR)中提取的RawdatAl-Khail健康服务的所有转诊数据进行了回顾性分析。计算了每月不适当转诊的比率和类型。在这项研究中,我们进行了前后分析,以评估两组干预措施对降低不适当转诊率的影响.第一套涉及2022年9月电子转诊培训手册的开发和分发。第二套,2023年4月实施,包括密切监测转介的比率和类型,并在健康服务主管和转介医生之间进行反馈沟通,以寻求建议和纠正措施。
    在研究期间共收到966次转诊,男女比例为1:5。在所有推荐中,34.9%被归类为不适当的,在不同的转诊保健中心之间表现出相当大的差异。不适当推荐的最常见原因是由于缺乏“运动健康健身房评估表”(23.8%)。虽然旨在加强转诊过程的干预措施,它们并未导致不适当转诊率的整体显著降低.然而,从2023年3月至8月观察到,由于缺乏“运动健康健身房评估表”而导致的不适当推荐显著减少(41%-18%)。
    这项研究揭示了健康服务推荐的复杂性,揭示了不适当的推荐率很高,需要更仔细的审查。尽管干预措施并未显着降低这些转诊率,它强调需要持续的改进策略。结构化,建议在更高级别进行定期干预,以提高转诊的适当性.
    UNASSIGNED: The objectives of this study were to explore the rate and types of inappropriate referrals to the wellness services and to assess the impact of multi-level interventions on the rate of inappropriate referrals at Rawdat Al-Khail health center in Qatar.
    UNASSIGNED: This study employed a retrospective analysis of all referrals data to Rawdat Al-Khail wellness services extracted from the Electronic Health Records (EHRs) between July 2022 and August 2023. The monthly rates and types of inappropriate referrals were calculated. In this study, pre-post analyses were performed to evaluate the impact of two sets of interventions on reducing inappropriate referral rates. The first set involved the development and distribution of e-referral pathways training manual in September 2022. The second set, implemented in April 2023, included close monitoring the rate and types of referrals, and the initiation of feedback communication between wellness services supervisors and referring physicians for advice and corrective actions.
    UNASSIGNED: A total of 966 referrals were received during the study period, with 1:5 male-to-female ratio. Of all referrals, 34.9 % were classified as inappropriate, exhibiting considerable variations among different referring health centers. The most common reason for inappropriate referrals was due to the lack of \"exercise wellness gym assessment form\" (23.8 %). While interventions aimed at enhancing the referral process, they did not result in a significant overall reduction in inappropriate referral rates. However, there was a noteworthy reduction in the inappropriate referrals caused by the lack of \"exercise wellness gym assessment form\" observed from March to August 2023 (41 %-18 %).
    UNASSIGNED: This study sheds light on the complexities of wellness services referrals, revealing a high rate of inappropriate referrals that require closer scrutiny. Despite interventions not significantly reducing the rate of these referrals, it emphasizes the need for ongoing improvement strategies. Structured, periodic interventions at higher levels are recommended to enhance referral appropriateness.
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  • 文章类型: Journal Article
    :当前研究的目的是评估与大流行前一年同期相比,2019年冠状病毒疾病大流行对精神卫生服务的影响。
    研究中的数据是从医院计算机系统的数据库中检索的。2019年3月1日至6月30日以及2020年3月1日至6月30日在儿童精神病学门诊的所有转诊均构成样本。
    在3110个转介中,2246例,重复检查864例。在2246起案件中,70.5%(n=1583)在2019年被录取,29.5%(n=663)在2020年被录取。在2019年转诊的病例中,37.3%(n=590)是女性,而2020年这一比率为43.9%(n=291)。2019年病例的平均年龄为9.51±4.17,而2020年病例的平均年龄为10.39±4.06。注意缺陷多动障碍,对立的反抗障碍,行为障碍,抑郁症,恐慌症,学校拒绝,睡眠障碍的发生率显著增加,发现特定的学习障碍和智力低下率在2020年下降。2019年,47.6%(n=754)的病例接受了药物治疗,到2020年,这一比率上升到63.2%(n=419)。
    大流行状况显着影响了公立医院精神科转诊的内容。可以认为,转诊人数的显着减少可能是由于公民遵守禁令和担心在儿童现有精神病问题之前大流行的家庭中疾病传播的结果。
    UNASSIGNED: : The objective of the current study was to assess how the coronavirus disease 2019 pandemic has affected mental health services compared to the same period of the year before the pandemic.
    UNASSIGNED: The data in the study were retrieved from the databases of the computer systems of the hospitals. All referrals in the child psychiatry outpatient clinic between March 1 and June 30, 2019, and between March 1 and June 30, 2020, constituted the sample.
    UNASSIGNED: Of the 3110 referrals, 2246 were cases and 864 were repeating examinations. Of the 2246 cases, 70.5% (n = 1583) were admitted in 2019, while 29.5% (n = 663) were admitted in 2020. Of the cases who referred in 2019, 37.3% (n = 590) were female, while this rate was 43.9% (n = 291) in 2020. The mean age of 2019 cases was found to be 9.51 ± 4.17, while the mean age of 2020 cases was found to be 10.39 ± 4.06. While attention-deficit hyperactivity disorder, oppositional defiant disorder, conduct disorder, depressive disorder, panic disorder, school refusal, and sleep disorder rates increased significantly, specific learning disorders and mental retardation rates were found to be on the decrease in 2020. In 2019, 47.6% (n = 754) of the cases were followed with medication, and in 2020, this rate increased to 63.2% (n = 419).
    UNASSIGNED: Pandemic conditions affected the content of public hospital psychiatry referrals significantly. It can be thought that the significant decrease in the number of referrals may be the result of citizens obeying the prohibitions and the fear of disease transmission in families with the onset of the pandemic that precedes the existing psychiatric problems of children.
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  • 文章类型: Journal Article
    在过去的十年里,在美国,年龄调整后的自杀率增加了35.2%.在初级保健中,从业者经常与有自杀风险的患者互动,然而,人们对初级保健人群中自杀风险的患病率知之甚少。2017-2020年的患者数据,包括从初级保健转诊并参加协作护理行为健康服务的全国患者样本(n=37666),进行了分析。控制人口特征,使用logistic模型通过行为健康诊断比较自杀风险患病率。估计有9.96%(95%置信区间[CI]:9.65-10.27)-或约3751个人-总样本的自杀风险筛查呈阳性。与被诊断为广泛性焦虑症的个体相比,被诊断为双相情感障碍的个体的自杀风险筛查几率为8.21倍(95%CI:6.66~10.10).从业者和医疗保健系统可能会受益于增加自杀风险筛查器作为转诊患者的标准做法,这可能导致临床路径和提供者培训的进一步发展。样本中自杀风险的高比率表明,需要更多的研究来了解初级保健和协作护理人群的自杀风险患病率。
    Over the past decade, the age-adjusted suicide rate has increased by 35.2% in the United States. In primary care, practitioners often interact with patients at risk of dying by suicide, yet little is known about the prevalence of suicide risk in primary care populations. Patient data from 2017-2020, consisting of a national sample of patients referred from primary care and enrolled in collaborative care behavioral health services (n = 37 666), were analyzed. Controlling for demographic characteristics, logistic models were used to compare suicide risk prevalence by behavioral health diagnosis. An estimated 9.96% (95% confidence interval [CI]: 9.65-10.27)-or approximately 3751 individuals-of the total sample screened positively for suicide risk. Compared with individuals diagnosed with generalized anxiety disorder, individuals diagnosed with bipolar disorder had 8.21 times the odds (95% CI: 6.66-10.10) of screening for suicide risk. Practitioners and health care systems may benefit from adding suicide risk screeners as a standard practice for referred patients, which may lead to further development of clinical pathways and provider training. The high rate of suicide risk across the sample suggests that more research is needed to understand suicide risk prevalence across primary care and collaborative care populations.
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  • 文章类型: Journal Article
    背景:本研究旨在提出一种半自动方法,用于在意大利国家卫生系统(NHS)内监测随访检查的等待时间,由于官方数据库中缺乏必要的结构化信息,目前尚不可能。
    方法:已经开发了一种基于自然语言处理(NLP)的管道,用于从推荐文本中提取等待时间信息,以便在伦巴第地区进行后续检查。10.000个推荐的手动注释数据集已用于开发管道,而10.000个推荐的另一个手动注释数据集已用于测试其性能。随后,该管道已用于分析2021年规定的所有1200万次推荐,并于2022年5月在伦巴第大区进行。
    结果:基于NLP的管道在从推荐文本中识别等待时间信息方面表现出高精度(0.999)和召回率(0.973),归一化精度高(0.948-0.998)。随访检查转介文本中时间指示的总体报告较低(2%),显示出不同医学学科和处方医生类型的显着差异。在报告等待时间的推荐中,16%的人经历了延误(平均延误=19天,标准偏差=34天),在医学学科和地理区域之间观察到显著差异。
    结论:使用NLP被证明是评估后续检查等待时间的宝贵工具,由于慢性病的重大影响,这对NHS尤其重要,后续考试至关重要。卫生当局可以利用此工具来监控NHS服务的质量并优化资源分配。
    BACKGROUND: This study aims to propose a semi-automatic method for monitoring the waiting times of follow-up examinations within the National Health System (NHS) in Italy, which is currently not possible to due the absence of the necessary structured information in the official databases.
    METHODS: A Natural Language Processing (NLP) based pipeline has been developed to extract the waiting time information from the text of referrals for follow-up examinations in the Lombardy Region. A manually annotated dataset of 10 000 referrals has been used to develop the pipeline and another manually annotated dataset of 10 000 referrals has been used to test its performance. Subsequently, the pipeline has been used to analyze all 12 million referrals prescribed in 2021 and performed by May 2022 in the Lombardy Region.
    RESULTS: The NLP-based pipeline exhibited high precision (0.999) and recall (0.973) in identifying waiting time information from referrals\' texts, with high accuracy in normalization (0.948-0.998). The overall reporting of timing indications in referrals\' texts for follow-up examinations was low (2%), showing notable variations across medical disciplines and types of prescribing physicians. Among the referrals reporting waiting times, 16% experienced delays (average delay = 19 days, standard deviation = 34 days), with significant differences observed across medical disciplines and geographical areas.
    CONCLUSIONS: The use of NLP proved to be a valuable tool for assessing waiting times in follow-up examinations, which are particularly critical for the NHS due to the significant impact of chronic diseases, where follow-up exams are pivotal. Health authorities can exploit this tool to monitor the quality of NHS services and optimize resource allocation.
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  • 文章类型: Journal Article
    轶事证据显示,过去两年(2020-2021年),主要三级医院的孕产妇死亡人数增加。我们审查了孕产妇死亡审计数据,确定了孕产妇死亡的主要原因,和相关的危险因素。与决策者分享了调查结果,以帮助降低孕产妇死亡率。
    我们对位于蒙罗维亚的三级医院的孕产妇死亡进行了二级数据回顾和描述性分析。
    孕产妇死亡数据是从患者病历中提取的,包括死亡证明和产妇审计记录。活产的记录是从分娩登记册中获得的。使用EpiInfo7.2版对数据进行分析,估计产妇死亡率(MMR),确定了孕产妇死亡的主要直接和间接原因,并使用5%显著性水平的logistic回归分析了与孕产妇死亡相关的因素。
    在本报告所述期间,共有233例孕产妇死亡和14,879例活产,孕产妇死亡率(MMR)为每100,000例活产1565例。死亡母亲的平均年龄为29岁(14-45岁)。约40.3%(94/233)的病例在入院后<1天内死亡,转诊占59%(137/233)。直接死因占66%(147/223)。出血[30.6%(45/147)],子痫[(30/147)20.6%]和脓毒症[(30/147)20.6%]是主要的直接死亡原因,心血管相关[18.4%(14/76)]和HIV/AIDS[16%(12/76)]是主要的间接原因。与未转诊的患者相比,转诊的其他机构的患者死亡可能性高7.9倍(pOR:7.9,95CI:5.9-10.6,p<0.001)。
    孕产妇死亡率仍然很高。转介时间晚了。利比里亚卫生部应配备更多的二级保健设施和三级医院,以处理孕产妇紧急情况,并提高民众和医护人员对迅速识别和转诊产科紧急情况的敏感性。卫生部还需要改善输血服务,以帮助管理产后出血。
    UNASSIGNED: Anecdotal evidence showed increased maternal deaths at the major tertiary hospital over the past two years (2020-2021). We reviewed the maternal death audit data, identified the main causes of maternal death, and associated risk factors. Findings were shared with policymakers to help reduce maternal mortality.
    UNASSIGNED: We conducted a secondary data review and descriptive analysis of maternal death at the tertiary hospital located in Monrovia.
    UNASSIGNED: The maternal death data were extracted from patient medical records, including death certificates and maternal audit records. The record of live births was obtained from the delivery register. Data were analyzed using Epi Info version 7.2 Maternal mortality ratio (MMR) was estimated, the leading direct and indirect causes of maternal death were identified, and the factors associated with maternal death were explored using logistic regression at a 5% level of significance.
    UNASSIGNED: There are a total of 233 maternal deaths and 14, 879 live births giving a maternal mortality ratio (MMR) of 1565 per 100,000 live births during the period under review. The median age of the mothers at death was 29 (14-45) years. About 40.3% (94/233) of cases died within <1 day of admission, referrals accounted for 59% (137/233) of the cases. Direct causes of death accounted for 66% (147/223). Hemorrhage [30.6% (45/147)], Eclampsia [(30/147) 20.6%] and Sepsis [(30/147) 20.6%] were the main direct causes of death while cardiovascular-related [18.4% (14/76)] and HIV/AIDS [16% (12/76)] were the leading indirect cause of death. Patients from referred other facilities were 7.9 times more likely to die as compared to non-referral (pOR:7.9, 95%CI: 5.9-10.6, p < 0.001).
    UNASSIGNED: The maternal mortality ratio remained high. Referrals were done late. The Liberia Ministry of Health should equip more secondary-level health facilities and tertiary hospitals to handle maternal emergencies and sensitize the populace and healthcare workers on prompt identification and referral of obstetric emergencies. The MoH also needs to improve the blood transfusion services to help in the management of postpartum hemorrhage.
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  • 文章类型: Journal Article
    口腔健康问题很常见,但经常被忽视,在接受姑息治疗的人群中。
    为了更好地了解如何在该人群中解决口腔健康问题,本研究旨在探讨提供姑息治疗的医生对口腔保健的看法,以指导姑息性口腔保健计划的制定。
    采用描述性定性设计。
    在悉尼的姑息治疗机构对18名医生进行了一个单一的焦点小组,澳大利亚。所有参与者都有为客户提供姑息治疗服务的经验。焦点小组被录音,转录和主题分析。
    归纳主题分析的结果确定了四个主题。主题强调,参与者了解接受姑息治疗的人的口腔健康需求;然而,他们还反映了在整个医疗机构中提供口腔保健的复杂性,以及围绕成本的挑战,缺乏适当的牙科转诊途径,时间限制和意识有限。参与者还提供了建议,以改善接受姑息治疗的个人的口腔保健服务。
    为了改善该人群的口腔保健,这项研究强调了跨多学科团队的口腔健康培训的必要性,标准化筛查评估和转介,全面承担集体责任,并探索远程医疗支持口腔保健提供的潜力。
    UNASSIGNED: Oral health problems are common, but often overlooked, among people receiving palliative care.
    UNASSIGNED: To better understand how oral health can be addressed in this population, this study aimed to explore the perceptions of oral health care among medical practitioners who provide palliative care to inform the development of a palliative oral health care program.
    UNASSIGNED: A descriptive qualitative design was adopted.
    UNASSIGNED: A single focus group was conducted with 18 medical practitioners at a palliative care facility in Sydney, Australia. All participants had experience providing palliative care services to clients. The focus group was audio recorded, transcribed and thematically analysed.
    UNASSIGNED: The results from the inductive thematic analysis identified four themes. The themes highlighted that participants were aware of the oral health needs of people receiving palliative care; however, they also reflected on the complexity in delivering oral health care across the healthcare settings, as well as the challenges around cost, lack of appropriate dental referral pathways, time constraints and limited awareness. Participants also provided recommendations to improve the delivery of oral health care to individuals receiving palliative care.
    UNASSIGNED: To improve the provision of oral health care in this population, this study highlighted the need for oral health training across the multidisciplinary team, standardised screening assessments and referrals, a collective responsibility across the board and exploring the potential for teledentistry to support oral health care provision.
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  • 文章类型: Journal Article
    本研究的目的是确定一般人群对风湿性疾病不同症状的认识,从患者的角度来看,诊断延误的关键因素,从症状发作到诊断的延迟时间,这对疾病活动的影响,对治疗的反应,以及诊断为风湿性疾病的患者的并发症和不可逆畸形的发展。
    这是一项横断面研究。我们的目标研究人群是沙特阿拉伯的居民。通过在线问卷收集数据,并用SPSS进行分析。
    我们队列中风湿性疾病的总体患病率为8.7%。关节痛(75.7%),关节肿胀(47.1%)和晨僵(32.9%)是第一和最常见的表现症状。症状持续(N=32,45.7%)和症状恶化(N=21,30.0%)是就诊风湿病学家的主要原因。与年龄≥50岁的患者相比,年龄<50岁的患者的首发症状与风湿性疾病诊断之间的持续时间明显更长。结果显示,年龄≥50岁的患者中有36.4%的患者因延迟预约而延迟诊断,而年龄<50岁的患者中这一比例为5.7%。此外,症状持续时间较长的患者可能会有更多的风湿病专家就诊.大多数<50岁的参与者明显同意风湿病学家治疗自身免疫性疾病,只有少数人批准他们治疗肌肉问题。
    我们研究的大多数参与者对他们的症状了解较少,他们不知道在哪里咨询他们的疾病治疗方法。这导致了不必要的延误以及症状的恶化和加重。越来越需要在普通人群中组织关于自身免疫和风湿性疾病的宣传运动。
    UNASSIGNED: The aim of this study is to determine the general population\'s knowledge on the different symptoms of rheumatic diseases, the key factors for diagnosis delays from the patient\'s perspective, the length of delay from the onset of symptoms to the diagnosis, and the effect this holds on the disease activity, response to therapy, and the development of complications and nonreversible deformities in patients diagnosed with rheumatic diseases.
    UNASSIGNED: This is a cross-sectional study. Our target study population were the residents of Saudi Arabia. Data were collected via an online questionnaire and analyzed with SPSS.
    UNASSIGNED: The overall prevalence of rheumatic disease in our cohort was 8.7%. Joint pain (75.7%), joint swelling (47.1%) and morning stiffness (32.9%) were the first and most common presenting symptom. Persistence of symptoms (N=32, 45.7%) and symptom worsening (N=21, 30.0%) was the predominant cause to visit rheumatologist. The duration between first symptom and rheumatic disease diagnosis is significantly longer for patients aged <50 years compared to that of those with ≥50 years of age. Results show that 36.4% of patients aged ≥50 years had delayed diagnosis due to late appointment compared with 5.7% of patients aged <50 years. In addition, patients with longer duration of symptoms were likely to have more visits to the rheumatologist. Most of the participants of <50 years significantly agreed that rheumatologists treat autoimmune diseases, only a few approved that they treat muscle problems.
    UNASSIGNED: Most participants in our study have lesser knowledge about their symptoms and they did not know where to consult for the treatment of their disease. This caused unnecessary delays and worsening and aggravation of the symptoms. There is an increased need to organize an awareness campaign in the general population regarding autoimmune and rheumatic diseases.
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  • 文章类型: Journal Article
    背景:在2016年之前,在专家中心诊断的孤立性同步结直肠腹膜转移(PMCRC)患者比在转诊中心诊断的患者接受腹腔热化疗(CRS-HIPEC)的细胞减灭术和总生存期(OS)的几率更高。在全国范围内开展了提高认识和改善转诊网络的努力。
    方法:这项全国性的研究旨在评估自从这些国家努力开始以来,中心之间接受CRS-HIPEC和OS的几率差异是否减少。所有在2009年至2021年之间诊断为孤立的同步PMCRC的患者均来自荷兰癌症注册中心。诊断医院与接受CRS-HIPEC的几率之间的关联,以及OS,使用多水平多变量回归分析评估了两个时期(2009-2015年和2016-2021年)。
    结果:总计,纳入3948例患者。接受CRS-HIPEC的患者比例从2009-2015年的17.2%增加(专家中心为25.4%,在转诊中心占16.5%),2016-2021年为23.4%(专家中心为30.2%,推荐中心的22.6%)。2009-2015年,与转诊中心的诊断相比,在HIPEC中心的诊断显示,接受CRS-HIPEC的几率较高(比值比[OR]1.64,95%置信区间[CI]1.02~2.67),生存率较好(风险比[HR]0.80,95%CI0.66~0.96).在2016-2021年,在HIPEC中心与转诊中心诊断的患者之间接受CRS-HIPEC的几率没有差异(OR1.27,95%CI0.76-2.13)和生存率(HR1.00,95%CI0.76-1.32)。
    结论:以前观察到的接受CRS-HIPEC的几率差异不再存在。提高对PMCRC的认识和统一治疗可能有助于在国家一级平等获得护理和类似的生存机会。
    BACKGROUND: Before 2016, patients with isolated synchronous colorectal peritoneal metastases (PMCRC) diagnosed in expert centers had a higher odds of undergoing cytoreductive surgery with hyperthermic intraperitoneal chemotherapy (CRS-HIPEC) and better overall survival (OS) than those diagnosed in referring centers. Nationwide efforts were initiated to increase awareness and improve referral networks.
    METHODS: This nationwide study aimed to evaluate whether the between-center differences in odds of undergoing CRS-HIPEC and OS have reduced since these national efforts were initiated. All patients with isolated synchronous PMCRC diagnosed between 2009 and 2021 were identified from the Netherlands Cancer Registry. Associations between hospital of diagnosis and the odds of undergoing CRS-HIPEC, as well as OS, were assessed using multilevel multivariable regression analyses for two periods (2009-2015 and 2016-2021).
    RESULTS: In total, 3948 patients were included. The percentage of patients undergoing CRS-HIPEC increased from 17.2% in 2009-2015 (25.4% in expert centers, 16.5% in referring centers), to 23.4% in 2016-2021 (30.2% in expert centers, 22.6% in referring centers). In 2009-2015, compared with diagnosis in a referring center, diagnosis in a HIPEC center showed a higher odds of undergoing CRS-HIPEC (odds ratio [OR] 1.64, 95% confidence interval [CI] 1.02-2.67) and better survival (hazard ratio [HR] 0.80, 95% CI 0.66-0.96). In 2016-2021, there were no differences in the odds of undergoing CRS-HIPEC between patients diagnosed in HIPEC centers versus referring centers (OR 1.27, 95% CI 0.76-2.13) and survival (HR 1.00, 95% CI 0.76-1.32).
    CONCLUSIONS: Previously observed differences in odds of undergoing CRS-HIPEC were no longer present. Increased awareness and the harmonization of treatment for PMCRC may have contributed to equal access to care and a similar chance of survival at a national level.
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  • 文章类型: Journal Article
    背景:脊髓性肌萎缩症(SMA)是一种常染色体隐性遗传性神经肌肉疾病,其特征是进行性肌肉无力和萎缩。临床试验数据表明,早期诊断和治疗至关重要。这项研究的目的是评估新生儿筛查确定的婴儿的神经病学预约等待时间,反映SMA症状的儿科病例,以及转诊医师怀疑SMA的病例。还探索了在美国分类和加快转介的方法。
    方法:CureSMA调查了来自两个队列的医疗保健专业人员:(1)SMA护理中心的附属提供者和(2)其他神经科医生,儿科神经科医生,和神经肌肉专家。调查直接通过MedscapeEducation分发,分别,2020年7月9日至2020年8月31日。
    结果:总共获得了三百五五个响应(9%来自SMA护理中心,91%来自一般招募样本)。如果最终被诊断为SMA1型的婴儿被转诊到SMA护理中心,而不是一般的样本实践,则诊断旅程较短。与一般招募实践相比,SMA护理中心表现出“张力减退和运动延迟”的婴儿的预约等待时间显着缩短(p=0.004)。此外,与一般招募中心相比,通过新生儿筛查确定的SMA患儿如果转诊至SMA护理中心更有可能更早被发现.最后,这两个队列中的大多数都对传入的转诊进行了分类。当使用一组“关键紧急单词”对初始转诊进行分类时,在SMA护理中心出现“张力减退和运动延迟”的婴儿的平均等待时间显着缩短(p=0.036)。
    结论:直接转诊到SMA护理中心的婴儿与一般样本诊所相比,更有可能经历较短的SMA诊断旅程和预约等待时间。针对“张力减退和运动延迟”的转诊的分诊指南,包括使用“关键紧急词汇”,可能会缩短等待时间,并支持SMA的早期诊断和治疗。
    BACKGROUND: Spinal muscular atrophy (SMA) is an autosomal recessive neuromuscular disease characterized by progressive muscle weakness and atrophy. Clinical trial data suggest early diagnosis and treatment are critical. The purpose of this study was to evaluate neurology appointment wait times for newborn screening identified infants, pediatric cases mirroring SMA symptomatology, and cases in which SMA is suspected by the referring physician. Approaches for triaging and expediting referrals in the US were also explored.
    METHODS: Cure SMA surveyed healthcare professionals from two cohorts: (1) providers affiliated with SMA care centers and (2) other neurologists, pediatric neurologists, and neuromuscular specialists. Surveys were distributed directly and via Medscape Education, respectively, between July 9, 2020, and August 31, 2020.
    RESULTS: Three hundred five total responses were obtained (9% from SMA care centers and 91% from the general recruitment sample). Diagnostic journeys were shorter for infants eventually diagnosed with SMA Type 1 if they were referred to SMA care centers versus general sample practices. Appointment wait times for infants exhibiting \"hypotonia and motor delays\" were significantly shorter at SMA care centers compared to general recruitment practices (p = 0.004). Furthermore, infants with SMA identified through newborn screening were also more likely to be seen sooner if referred to a SMA care center versus a general recruitment site. Lastly, the majority of both cohorts triaged incoming referrals. The average wait time for infants presenting at SMA care centers with \"hypotonia and motor delay\" was significantly shorter when initial referrals were triaged using a set of \"key emergency words\" (p = 0.036).
    CONCLUSIONS: Infants directly referred to a SMA care center versus a general sample practice were more likely to experience shorter SMA diagnostic journeys and appointment wait times. Triage guidelines for referrals specific to \"hypotonia and motor delay\" including use of \"key emergency words\" may shorten wait times and support early diagnosis and treatment of SMA.
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  • 文章类型: Journal Article
    目的:心理社会康复(PSR)是精神病康复的核心。关于患者的需求和特征如何指导临床决策参考PSR干预措施的证据很少。这里,我们使用可解释的机器学习方法来确定社会人口统计学和临床特征如何影响严重精神疾病患者的PSR干预措施.
    方法:数据来自法国康复中心网络,REHABase,在2016年至2022年之间收集,并在2022年2月至9月之间进行分析。参与者患有严重的精神疾病,包括精神分裂症谱系障碍,双相情感障碍,自闭症谱系障碍,抑郁症,焦虑症和人格障碍。在基线时从37个社会人口统计学和临床变量中提取信息,并将其用作潜在的预测因子。测试了几种机器学习模型,以预测对四种PSR干预的初始推荐:认知行为治疗(CBT),认知修复(CR),心理教育(PE)和职业培训(VT)。预测因子的解释能力是使用基于人工智能的SHAP(SHapley加法扩张)方法从最佳性能算法中确定的。
    结果:纳入了总共1146例患者的数据(平均年龄,33.2年[范围,16-72岁];366名[39.2%]女性)。随机森林算法表现出最佳的预测性能,具有中等或平均预测精度[来自外部交叉验证的接收器工作曲线下的微平均面积:0.672]。SHAP依赖性图显示了社会人口统计学和临床预测因子与推荐PSR计划之间的深刻关联。例如,精神病患者更有可能被称为PE和CR,而那些非精神病性障碍患者更有可能被称为CBT和VT。同样,社会功能障碍和缺乏教育程度的患者更有可能被转诊至CR和VT,而那些功能和教育更好的人更有可能被称为CBT和体育。
    结论:社会人口统计学和临床特征的组合不足以准确预测法国康复中心网络中四个PSR计划的初始转诊。对PSR干预的转介也可能涉及服务和临床医生水平的因素。考虑到社会人口统计学和临床预测因素,在转诊方面存在差异。目前的临床和心理问题,功能和教育。
    OBJECTIVE: Psychosocial rehabilitation (PSR) is at the core of psychiatric recovery. There is a paucity of evidence regarding how the needs and characteristics of patients guide clinical decisions to refer to PSR interventions. Here, we used explainable machine learning methods to determine how socio-demographic and clinical characteristics contribute to initial referrals to PSR interventions in patients with serious mental illness.
    METHODS: Data were extracted from the French network of rehabilitation centres, REHABase, collected between years 2016 and 2022 and analysed between February and September 2022. Participants presented with serious mental illnesses, including schizophrenia spectrum disorders, bipolar disorders, autism spectrum disorders, depressive disorders, anxiety disorders and personality disorders. Information from 37 socio-demographic and clinical variables was extracted at baseline and used as potential predictors. Several machine learning models were tested to predict initial referrals to four PSR interventions: cognitive behavioural therapy (CBT), cognitive remediation (CR), psychoeducation (PE) and vocational training (VT). Explanatory power of predictors was determined using the artificial intelligence-based SHAP (SHapley Additive exPlanations) method from the best performing algorithm.
    RESULTS: Data from a total of 1146 patients were included (mean age, 33.2 years [range, 16-72 years]; 366 [39.2%] women). A random forest algorithm demonstrated the best predictive performance, with a moderate or average predictive accuracy [micro-averaged area under the receiver operating curve from \'external\' cross-validation: 0.672]. SHAP dependence plots demonstrated insightful associations between socio-demographic and clinical predictors and referrals to PSR programmes. For instance, patients with psychotic disorders were more likely to be referred to PE and CR, while those with non-psychotic disorders were more likely to be referred to CBT and VT. Likewise, patients with social dysfunctions and lack of educational attainment were more likely to be referred to CR and VT, while those with better functioning and education were more likely to be referred to CBT and PE.
    CONCLUSIONS: A combination of socio-demographic and clinical features was not sufficient to accurately predict initial referrals to four PSR programmes among a French network of rehabilitation centres. Referrals to PSR interventions may also involve service- and clinician-level factors. Considering socio-demographic and clinical predictors revealed disparities in referrals with respect to diagnoses, current clinical and psychological issues, functioning and education.
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