■很少有西班牙正念干预措施在拉丁裔癌症患者中得到评估。我们在文化上对讲西班牙语的拉丁裔患者进行了正念干预。目标是衡量可行性和可接受性作为主要结果,随着焦虑的变化,抑郁症,睡眠是次要结果。
■将讲西班牙语的拉丁裔乳腺癌患者(n=31)随机分组,2021年4月至2022年5月,干预组或等待名单对照组。正念干预包括由新手主持人远程提供的每周6次1.5小时的会议。文化适应包括语言,隐喻,隐喻目标,概念,创伤知情,和对灵性的承认。可行性的基准是75%的参与者参加他们的第一届会议,75%的参与者完成了6个课程中的4个,并且在5分Likert可得性量表上评分≥4分,测量6周后实施变化的能力。可接受性被测量为在5点Likert量表上得分≥4,测量每节正念干预的有效性和相关性。意向治疗,具有重复测量分析的线性混合模型检查了焦虑的变化,抑郁症,和睡眠在第6周和第18周(干预后3个月)。
■所有三个可行性基准都满足了第一届会议的75%的出席,96%的参与者完成了6个课程中的4个,在可行性量表上,94%评分≥4分(平均值(SD)=4.3(0.6))。在所有6个课程中,有用性和相关性问题的可接受性得分均≥4。焦虑在3个月时显著降低(-3.6(CI-6.9,-0.2),P=.04),但鉴于微小的变化,其临床意义尚不清楚。抑郁评分下降,但并不重要,睡眠没有变化。
■这种文化适应,使用新手促进者远程提供的正念干预是可以接受的,也是可行的,并且在讲西班牙语的拉丁裔乳腺癌患者中显示出相关的焦虑减轻.
■ClinicalTrials.govID#NCT04834154。
UNASSIGNED: Few Spanish mindfulness interventions have been evaluated in Latinx patients with cancer. We culturally adapted a mindfulness intervention for Spanish speaking Latinx patients. The objective was to measure feasibility and acceptability as primary outcomes, with changes in anxiety, depression, and sleep as secondary outcomes.
UNASSIGNED: Spanish-speaking Latinx patients with breast cancer (n = 31) were randomized, between April 2021 and May 2022 to either intervention or wait-list control groups. The mindfulness intervention consisted of 6-weekly 1.5-hour sessions remotely delivered by a novice facilitator. Cultural adaptations included language, metaphor, goal, concept, trauma informed, and acknowledgement of spirituality. Feasibility was benchmarked as 75% of participants attending their first session, 75% of participants completing 4 of 6 sessions, and scoring ≥ 4 on a 5-point Likert feasability scale measuring ability to implement changes after 6-weeks. Acceptability was measured as scoring ≥ 4 on a 5-point Likert scale measuring usefulness and relevance of the mindfulness intervention for each session. An intention-to-treat, linear mixed model with repeated measures analysis examined changes in anxiety, depression, and sleep at week 6 and 18 (3 months post intervention).
UNASSIGNED: All three feasibility benchmarks were met with 75% of first session attendance, 96% of participants completing 4 of 6 sessions, and 94% scoring ≥ 4, on the feasibility scale (Mean (SD) = 4.3 (0.6)). Acceptability scores for both usefulness and relevance questions were ≥ 4 across all 6 sessions. Anxiety was significantly reduced at 3 months (-3.6 (CI -6.9, -0.2), P = .04), but is of unclear clinical significance given the small change. Depression scores declined, but not significantly, and there were no changes in sleep.
UNASSIGNED: This culturally adapted, remotely delivered mindfulness intervention using a novice facilitator was acceptable and feasible and demonstrated associated reductions in anxiety amongst Spanish speaking Latinx patients with breast cancer.
UNASSIGNED: ClinicalTrials.gov ID# NCT04834154.