背景:为了研究对跌倒风险有影响的因素,并确定放射学膝关节骨关节炎(KOA)是否是独立于膝关节疼痛的跌倒因素,心理因素,和身体功能。
方法:在Aizu队列研究(LOHAS)中对1083名受试者进行了2009年机车综合征和健康结果的横断面分析。进行了逻辑回归分析,以检查影像学KOA与跌倒史之间的关系。
结果:跌倒史与膝关节疼痛的严重程度显著相关。与没有膝盖疼痛的受试者相比,轻度膝关节疼痛的受试者的比值比(OR)是1.53倍(95%置信区间[CI]:1.04-2.25),中度膝关节疼痛的患者高1.69倍(95CI:1.03-2.79),和2.98倍,在那些严重的膝关节疼痛(95CI:1.67-5.30)。在抑郁症患者中,OR为1.91(95CI:1.25-2.92),在那些行动不便的人中,OR为1.70(95CI:1.08-2.69)。年龄,性别,膝盖蠕动,BMI,奥斯特,安眠药的使用与跌倒风险无显著相关.在多变量分析中,影像学KOA严重程度与跌倒风险无显著相关(轻度OA的OR0.81,95CI0.44-1.50;重度OA的OR1.10,95CI0.57-2.14).
结论:膝关节疼痛,流动性下降,和抑郁症,但不是射线照相KOA的严重程度,与跌倒风险显著相关。无论个人的射线照相KOA严重程度如何,可以通过治疗他/她的膝盖疼痛来降低跌倒的风险,流动性问题,和/或心理因素。
BACKGROUND: To investigate factors that have an impact on the risk of falls and determine whether radiographic knee osteoarthritis (KOA) is a factor involved in falls independent of knee pain, psychological factors, and physical function.
METHODS: A cross-sectional analysis was conducted on 1083 subjects for the 2009 Locomotive Syndrome and Health Outcomes in the Aizu Cohort Study (LOHAS). A logistic regression analysis was performed to examine the relationship between radiographic KOA and fall history.
RESULTS: Fall history was significantly associated with the severity of knee pain. Compared to subjects with no knee pain, the odds ratio (OR) was 1.53 times higher in the subjects with mild knee pain (95% confidence interval [CI]: 1.04-2.25), 1.69 times higher in those with moderate knee pain (95%CI: 1.03-2.79), and 2.98 times higher in those with severe knee pain (95%CI: 1.67-5.30). In subjects with depression, the OR was 1.91 (95%CI: 1.25-2.92), and in those with decreased mobility, the OR was 1.70 (95%CI: 1.08-2.69). Age, gender, knee crepitus, BMI, OLST, and sleeping pill use were not significantly associated with fall risk. In a multivariate analysis, radiographic KOA severity was not significantly associated with fall risk (OR 0.81, 95%CI 0.44-1.50 in mild OA; OR 1.10, 95%CI 0.57-2.14 in severe OA).
CONCLUSIONS: Knee pain, decreased mobility, and depression, but not the radiographic KOA severity, were significantly associated with a fall risk. Regardless of the individual\'s radiographic KOA severity, the risk of falls may be reduced by treating his/her knee pain, mobility problems, and/or psychological factors.