Instability

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  • 文章类型: Case Reports
    胫腓关节近端(PTFJ)半脱位很少见,可在外伤或体育赛事后发生。特发性PTFJ半脱位在女性和全身韧带松弛患者中更为常见。正确的病史和临床检查以及影像学检查可以帮助在大多数情况下建立诊断。
    我们报告了一例罕见的双侧PTFJ半脱位病例,并描述了详细的临床特征和磁共振成像结果。对患者进行了保守治疗,效果良好。
    PTFJ的双侧半脱位是一种罕见的临床实体,通常与特定的人口统计学和身体特征有关,例如从事高影响力运动的年轻女性。此病例强调了进行彻底的临床和影像学评估以将其与膝关节外侧疼痛和突出的其他原因区分开的重要性。保守管理,包括物理治疗和常规随访,已经证明在控制症状和避免进展方面是有效的,强调治疗这种情况的非手术方法。
    UNASSIGNED: Proximal tibiofibular joint (PTFJ) subluxations are rare and can occur following trauma or sporting events. Idiopathic PTFJ subluxations are more common in females and in patients with generalized ligament laxity. The proper history and clinical examination together with imaging can help in establishing the diagnosis in the majority of cases.
    UNASSIGNED: We report a rare case of bilateral subluxation of PTFJ and describe the detailed clinical features and magnetic resonance imaging findings. The patient was managed conservatively with good results.
    UNASSIGNED: Bilateral subluxation of the PTFJ is a rare clinical entity often associated with specific demographic and physical characteristics, such as young females engaged in high-impact sports. This case underscores the importance of a thorough clinical and imaging evaluation to differentiate it from other causes of lateral knee pain and prominence. Conservative management, including physical therapy and routine follow-ups, has proven effective in managing symptoms and avoiding progression, highlighting the non-operative approach in treating this condition.
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  • 文章类型: Case Reports
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  • 文章类型: Journal Article
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  • 文章类型: Journal Article
    如果没有正确诊断,小儿颈椎损伤可能会造成毁灭性后果。疑似颈椎损伤的标准检查包括颈椎X射线和高分辨率CT。如果怀疑仍然存在,则获得宫颈MRI。当宫颈MRI显示韧带水肿但无法确定韧带的完整性时,则需要进行额外的检查。通常,弯曲和伸展颈椎外侧X射线可以帮助确定非镇静合作年龄适当的患者的韧带完整性。对于无法进行屈伸X线检查的儿科患者,我们在麻醉下对颈椎进行动态透视检查.患者处于仰卧位。C形臂位于横向位置。外科医生手动分散注意力,屈曲,扩展,和平移操作,同时获得实时透视和评估宫颈不稳定的迹象。如果存在宫颈不稳定,则可以进行适当的确定性治疗。如果颈椎稳定,则可以停止颈椎固定。
    Cervical spine injuries in pediatric patients can have devastating consequences if not properly diagnosed. The standard workup for suspected cervical spine injuries includes cervical X-rays and a high-resolution CT. If suspicion still exists then a cervical MRI is obtained. When the cervical MRI shows ligamentous edema but is unable to determine the integrity of the ligaments then additional workup is needed. Often a flexion and extension lateral cervical X-ray can help determine ligament integrity in the non-sedated cooperative age-appropriate patient. For pediatric patients who are unable to perform the flexion and extension X-ray, we perform a dynamic fluoroscopic examination of the cervical spine under anesthesia. The patient is positioned in the supine position. The C-arm is positioned in the lateral position. The surgeon manually performs distraction, flexion, extension, and translation maneuvers while obtaining live fluoroscopy and assessing for signs of cervical instability. If cervical instability exists then the appropriate definitive treatment can be performed. If the cervical spine is stable then cervical immobilization can be discontinued.
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  • 文章类型: Journal Article
    背景:退变性腰椎管狭窄症(LSS)是一种常见的疾病,涉及椎管狭窄。传统上,诊断不稳定性需要站立的横向射线照片来检测动态平移,但是,由于患者的不适和辐射暴露等挑战,有关于完全依赖射线照片的争论。这项研究旨在评估磁共振成像(MRI)的发现是否可以有效地诊断X射线照片上观察到的不稳定性。
    方法:我们回顾了在我们机构接受手术的478例退行性LSS患者。不稳定定义为在伸展和屈曲的站立侧位X线片上的矢状平移超过3mm。将患者分为稳定组(平移<3mm的组)和不稳定组(平移>3mm的组)。这项研究评估了潜在的不稳定变量,包括小关节积液等MRI表现,面接头角度,磁盘高度索引,椎间盘内真空存在,终板硬化,黄韧带肥大,多裂肌脂肪变性,比较两组之间的这些因素。
    结果:共纳入478例连续诊断为退行性腰椎管狭窄(LSS)的患者。患者平均年龄为66.32岁,其中43.3%是男性。大约27.6%的病例在伸展和屈曲期间在站立的侧面X光片上表现出不稳定的迹象。使用二元逻辑回归的多变量分析显示小关节积液(比值比[OR]2.73;95%置信区间[CI]1.27-3.94;P=0.002),圆盘高度指数(OR2.22;95%CI1.68-3.35;P=0.009),和真空体征的存在(OR1.77;95%CI1.32-2.84;P=0.021)被确定为与不稳定性相关的因素。
    结论:我们的研究结果表明较高的小关节积液,真空标志的存在,在退行性LSS患者中,较大的椎间盘高度指数与站立侧位X线片上的伸展和屈曲不稳定有关。
    BACKGROUND: Degenerative lumbar spinal stenosis (LSS) is a common condition that involves the narrowing of the spinal canal. Diagnosing instability traditionally requires standing lateral radiographs to detect dynamic translation, but there is debate about relying solely on radiographs due to challenges like patient discomfort and radiation exposure. This study aimed to evaluate if Magnetic Resonance Imaging (MRI) findings could effectively diagnose instability observed on radiographs.
    METHODS: We reviewed 478 consecutive patients with degenerative LSS who had surgery at our institution. Instability was defined as a sagittal translation exceeding 3 mm on standing lateral radiographs in both extension and flexion. Patients were divided into stable (those with < 3 mm translation) and unstable groups (those with > 3 mm translation). The study assessed potential variables for instability, including MRI findings like facet joint effusion, facet joint angle, disk height index, intradiscal vacuum presence, endplate sclerosis, ligamentum flavum hypertrophy, and multifidus muscle fatty degeneration, comparing these factors between the two groups.
    RESULTS: A total of 478 consecutive patients diagnosed with degenerative Lumbar Spinal Stenosis (LSS) were included. The average age of the patients was 66.32 years, with 43.3% being male. Approximately 27.6% of the cases exhibited signs of instability on the standing lateral radiograph during extension and flexion. The multivariate analysis using binary logistic regression revealed that facet joint effusion (odds ratio [OR] 2.73; 95% confidence interval [CI] 1.27-3.94; P = 0.002), disk height index (OR 2.22; 95% CI 1.68-3.35; P = 0.009), and the presence of the Vacuum sign (OR 1.77; 95% CI 1.32-2.84; P = 0.021) were identified as factors associated with instability.
    CONCLUSIONS: Our findings showed thata higher facet joint effusion, the presence of Vacuum sign, and a greater Disk Height Index were associated with the presence of instability on the standing lateral radiograph in extension and flexion in patients with degenerative LSS.
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  • 文章类型: Journal Article
    翻修全髋关节置换术(rTHA)的结果随着其体积的增加而变得越来越重要。电脑导航,一种在初次全髋关节置换术(THA)期间改善组件定位的可靠方法,在RTHA设置中没有很好的研究。鉴于rTHA后的位错率明显高于初级THA,在这些情况下,组件定位变得至关重要。
    这里,我们提供了两个病例报告和手术技术,一名77岁男子因原发性THA后复发性髋关节不稳定而接受RTHA,一名61岁女性因严重髂腰滑囊炎接受rTHA治疗,由于有大节段脊柱融合术史,不稳定和脱位的风险增加。
    两名患者均在rTHA后通过无图像计算机导航实现了最佳的髋臼组件定位。
    在rTHA中使用无图像计算机导航可在髋臼rTHA期间提供准确且可重复的组件定位。
    UNASSIGNED: The outcomes of revision total hip arthroplasty (rTHA) have become increasingly important as their volume increases. Computer navigation, a reliable method to improve component positioning during primary total hip arthroplasty (THA), is not well studied in the rTHA setting. Given that dislocation rates following rTHA are significantly higher than those of primary THA, component positioning becomes paramount in these cases.
    UNASSIGNED: Here, we present two case reports and surgical techniques, one of a 77-year-old man undergoing rTHA for recurrent hip instability following primary THA, and one of a 61-year-old woman undergoing rTHA for severe iliopsoas bursitis who was at increased risk for instability and dislocation given her history of large segment spinal fusion.
    UNASSIGNED: Both patients achieved optimal acetabular component positioning after rTHA with imageless computer navigation.
    UNASSIGNED: The use of imageless computer navigation in rTHA provides accurate and reproducible component positioning during acetabular rTHA.
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  • 文章类型: Journal Article
    肩锁关节(ACJ)损伤是一种常见的骨科疾病,占所有肩部损伤的40%以上。这项研究的目的是评估ACJ不稳定性的前50篇被引用文章的研究趋势和特征。
    在WebofScience中进行了系统搜索,以确定主要与ACJ损伤或不稳定有关的文章。特征包括引文编号,原产国,期刊和出版机构,影响因子,作者身份,证据水平,患者人口统计学,和研究类型进行分析和记录。
    关于ACJ不稳定性的研究产出一直在稳步增长,被引用的前50项研究主要提供IV级证据。这些研究主要集中在治疗结果上,主要包括男性患者,并且引文计数差异很大。美国运动医学杂志是最有成效的杂志,美国是生产力最高的国家。
    ACJ不稳定性文献中的出版物越来越多,主要集中在一些机构和期刊上,主要关注治疗结果。这些出版物中有很大一部分科学质量低下,并且明显缺乏对女性结果的研究。
    UNASSIGNED: Acromioclavicular joint (ACJ) injury is a common orthopaedic condition accounting for over 40 % of all shoulder injuries. The purpose of this study is to assess the research trends and characteristics of the top 50 cited articles on ACJ instability.
    UNASSIGNED: A systematic search was conducted in Web of Science to identify articles primarily related to ACJ injury or instability. Characteristics including citation number, country of origin, journal and institution of publication, impact factor, authorship, level of evidence, patient demographics, and study type were analyzed and recorded.
    UNASSIGNED: Research output on ACJ instability has been steadily increasing, with the top 50 cited studies predominantly presenting Level IV evidence. These studies primarily focused on treatment outcomes which included predominantly male patients and exhibited a large variation in citation counts. The American Journal of Sports Medicine was the most productive journal, and the USA was the most productive nation.
    UNASSIGNED: There is an increasing number of publications in the ACJ instability literature, primarily concentrated in a few institutions and journals, and focusing mainly on treatment outcomes. A significant portion of these publications are of low scientific quality, and there is a notable lack of research on outcomes for females.
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  • 文章类型: Journal Article
    本研究探讨了静电相互作用和氢键对泪膜稳定性的影响,眼表健康的关键因素。虽然粘膜层和睑板层已经被广泛研究,电解质在水相中的作用尚不清楚。干眼综合征,以撕裂数量或质量不足为特征,与高渗透压有关,使电解质成分成为可能影响撕裂稳定性的重要因素。在石英玻璃圆顶上使用模型缓冲溶液,我们模拟了生理相关的泪膜条件。单独的氯化钠通过盐晶体成核引起过早的去润湿。相比之下,微量含羟基的溶质(磷酸氢二钠,磷酸二氢钾,和葡萄糖)表现出有趣的现象:准稳定的薄膜,SolutalMarangoni驱动的流体流入增加了薄膜厚度,和粘性指法由于萨夫曼-泰勒的不稳定性。这些观察结果通过与表面张力增加的盐溶液和含羟基溶质参与显著氢键键合的倾向的结合而合理化。改变局部粘度。这在本体缓冲溶液和膜区域之间产生了粘度对比。此外,这些溶质屏蔽了玻璃圆顶,抵消氯化钠结晶。这些见解不仅促进了我们对泪膜力学的理解,而且为干眼综合征的预测性诊断铺平道路。为基于个人泪膜成分的个性化医疗干预提供了一个强大的平台。
    This study explores the impact of electrostatic interactions and hydrogen bonding on tear film stability, a crucial factor for ocular surface health. While mucosal and meibomian layers have been extensively studied, the role of electrolytes in the aqueous phase remains unclear. Dry eye syndrome, characterized by insufficient tear quantity or quality, is associated with hyperosmolality, making electrolyte composition an important factor that might impact tear stability. Using a model buffer solution on a silica glass dome, we simulated physiologically relevant tear film conditions. Sodium chloride alone induced premature dewetting through salt crystal nucleation. In contrast, trace amounts of solutes with hydroxyl groups (sodium phosphate dibasic, potassium phosphate monobasic, and glucose) exhibited intriguing phenomena: quasi-stable films, solutal Marangoni-driven fluid influx increasing film thickness, and viscous fingering due to Saffman-Taylor instability. These observations are rationalized by the association of salt solutions with increased surface tension and the propensity of hydroxyl-group-containing solutes to engage in significant hydrogen bonding, altering local viscosity. This creates a viscosity contrast between the bulk buffer solution and the film region. Moreover, these solutes shield the glass dome, counteracting sodium chloride crystallization. These insights not only advance our understanding of tear film mechanics but also pave the way for predictive diagnostics in dry eye syndrome, offering a robust platform for personalized medical interventions based on individual tear film composition.
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  • 文章类型: Journal Article
    开发了Latarjet程序,用于治疗年轻的肩关节前不稳定,高需求的磨耗性关节盂骨丢失患者,其初级位错后再位错的风险可能超过90%。在手术后重新出现的患者的晚期计算机断层扫描(CT)扫描中通常会观察到喙突移植物骨质溶解和突出的螺钉,但在整个Latarjet队列中骨质溶解的临床相关性尚未确定.我们旨在评估接受Latarjet手术的患者的临床和放射学结果,并确定严重的喙突移植物骨溶解是否损害了临床结果。
    这是对接受开放式Latarjet手术的患者的回顾性分析。通过包含西安大略肩关节不稳定指数(WOSI)的电子问卷邀请患者,并询问了索引手术以来的再脱位和再手术。使用最佳拟合圆法在CT上计算术前关节盂骨丢失。骨溶解分别在近端和远端螺钉的水平上进行分级(0,螺钉头埋在移植物中;1,螺钉头暴露;2,螺纹暴露;3,完全吸收/严重骨溶解)。术后≥12个月进行轴向CT扫描。
    在2011年至2022年之间,一名外科医生进行了442Latarjet手术。158名患者在术后44(27-70)个月的中位数(四分位距[IQR])回答了问卷,其中中位数(IQR)WOSI评分为352(142-666)分(0=最佳,2100=最差)。3/158(2%)患者发生复发性前不稳。一名患者为此适应症需要再次手术。在术后CT扫描≥12个月(中位数[IQR]40[29-69]个月)的患者中,1例患者在两个螺钉周围出现严重的骨质溶解(WOSI=90),17/62(27%)患者在1个螺钉周围出现严重的骨溶解,所有这些都是近端(中位数[IQR]WOSI=235[135-644]),44/62(71%)患者在任一螺钉周围均未出现严重骨质溶解(中位数[IQR]WOSI=487[177-815]).基于严重骨质溶解的存在,两组之间的WOSI评分没有统计学上的显着差异。
    Latarjet是可靠的程序,其再脱位和再手术率低。随着时间的推移,喙突移植物会出现严重的骨质溶解,并且总是首先影响近端移植物。严重骨质溶解的存在并不影响临床结果。
    UNASSIGNED: The Latarjet procedure was developed for the treatment of anterior shoulder instability in young, high-demand patients with attritional glenoid bone loss, whose risk of redislocation following primary dislocation may exceed 90%. Coracoid graft osteolysis and prominent screws are commonly observed in late computed tomography (CT) scans of patients who re-present following the procedure, but the clinical relevance of osteolysis in the overall Latarjet cohort is undetermined. We aimed to evaluate clinical and radiological outcomes in patients who underwent the Latarjet procedure, and to determine if severe coracoid graft osteolysis compromised clinical outcomes.
    UNASSIGNED: This was a retrospective analysis of patients who underwent the open Latarjet procedure. Patients were invited via an e-questionnaire that contained a Western Ontario Shoulder Instability Index (WOSI), and queried about redislocation and reoperation since index surgery. Preoperative glenoid bone loss was calculated on CT using the best-fit circle method. Osteolysis was graded (0, screw head buried in graft; 1, screw head exposed; 2, threads exposed; 3, complete resorption/severe osteolysis) at the level of the proximal and distal screws respectively, on axial CT scans performed ≥ 12 months postoperatively.
    UNASSIGNED: Between 2011 and 2022, a single surgeon performed 442 Latarjet procedures. One hundred fifty eight patients responded to the questionnaire at median (interquartile range [IQR]) 44 (27-70) months postoperatively, among whom the median (IQR) WOSI score was 352 (142-666) points (0 = best, 2100 = worst). Recurrent anterior instability occurred in 3/158 (2%) patients. One patient required reoperation for this indication. Among patients who had CT scans ≥ 12 months postoperatively (median [IQR] 40 [29-69] months), 1 patient developed severe osteolysis around both screws (WOSI = 90), 17/62 (27%) patients developed severe osteolysis around 1 screw, all of which were proximal (median [IQR] WOSI = 235 [135-644]), and 44/62 (71%) patients did not develop severe osteolysis around either screw (median [IQR] WOSI = 487 [177-815]). There were no statistically significant differences in WOSI scores between groups based on the presence of severe osteolysis.
    UNASSIGNED: The Latarjet is reliable procedure that has a low rate of redislocation and reoperation. Severe coracoid graft osteolysis occurs with time, and always affects the proximal graft first. The presence of severe osteolysis did not compromise clinical outcomes.
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  • 文章类型: Journal Article
    磨玻璃结节(GGN)是肺腺癌在计算机断层扫描(CT)上最常见的表现。临床上,经穿刺活检等手段术前诊断GGN的成功率仍然较低。本研究的目的是利用影像组学分析方法探讨在CT图像上表现为GGN的肺腺癌的临床和影像组学特征。建立一个影像组学模型,并预测GGN型肺腺癌的病理组织分类和不稳定性。
    本研究回顾性收集了249例经病理证实为肺腺癌的298例GGN病变患者。将图像导入到西门子科学研究原型软件中,以勾勒出感兴趣的区域并提取影像组学特征。使用降维过程后的特征建立Logistic模型A(用于识别表现为GNs的肺腺癌浸润的放射组学模型)。绘制了模型在训练集和验证集上的受试者工作特性(ROC)曲线,并计算曲线下面积(AUC)。第二,从至少两次CT图像来源的298个病灶中,共选择112个病灶,首次CT与术前CT之间的时间定义为不少于90天。计算所有病灶的质量倍增时间(MDT)。根据不同的MDT诊断阈值预测不稳定性。最后,计算并比较了它们的AUC.
    无创性病变组与有创性病变组的年龄和病变部位分布差异有统计学意义(P<0.05),但性别差异无统计学意义(P>0.05)。模型A在训练集中具有0.89的AUC、0.75的灵敏度和0.86的特异性,并且在验证集中具有0.87的AUC、0.63的灵敏度和0.90的特异性。“非侵袭性”病变与侵袭性病变之间的MDT差异无统计学意义(P>0.05)。影像组学模型B1、B2和B3的AUC分别为0.89、0.80和0.81;敏感性分别为0.71、0.54和0.76;特异性分别为0.83、0.77和0.60;准确性分别为0.78、0.65和0.69。
    “非侵入性”病变组与侵入性病变组之间的年龄和病变位置有统计学上的显着差异。影像组学模型可以预测表现为GGN的肺腺癌的侵袭性。“非侵入性”病变和侵入性病变之间的MDT没有显着差异。影像组学模型可以预测表现为GGN的肺腺癌的不稳定性。当MDT的阈值设置为813天时,该模型具有较高的特异性,准确度,诊断效率。
    UNASSIGNED: Ground-glass nodule (GGN) is the most common manifestation of lung adenocarcinoma on computed tomography (CT). Clinically, the success rate of preoperative diagnosis of GGN by puncture biopsy and other means is still low. The aim of this study is to investigate the clinical and radiomics characteristics of lung adenocarcinoma presenting as GGN on CT images using radiomics analysis methods, establish a radiomics model, and predict the classification of pathological tissue and instability of GGN type lung adenocarcinoma.
    UNASSIGNED: This study retrospectively collected 249 patients with 298 GGN lesions who were pathologically confirmed of having lung adenocarcinoma. The images were imported into the Siemens scientific research prototype software to outline the region of interest and extract the radiomics features. Logistic model A (a radiomics model to identify the infiltration of lung adenocarcinoma manifesting as GGNs) was established using features after the dimensionality reduction process. The receiver operating characteristic (ROC) curve of the model on training set and the verification set was drawn, and the area under the curve (AUC) was calculated. Second, a total of 112 lesions were selected from 298 lesions originating from CT images of at least two occasions, and the time between the first CT and the preoperative CT was defined as not less than 90 days. The mass doubling time (MDT) of all lesions was calculated. According to the different MDT diagnostic thresholds instability was predicted. Finally, their AUCs were calculated and compared.
    UNASSIGNED: There were statistically significant differences in age and lesion location distribution between the \"noninvasive\" lesion group and the invasive lesion group (P<0.05), but there were no statistically significant differences in sex (P>0.05). Model A had an AUC of 0.89, sensitivity of 0.75, and specificity of 0.86 in the training set and an AUC of 0.87, sensitivity of 0.63, and specificity of 0.90 in the validation set. There was no significant difference statistically in MDT between \"noninvasive\" lesions and invasive lesions (P>0.05). The AUCs of radiomics models B1, B2 and B3 were 0.89, 0.80, and 0.81, respectively; the sensitivities were 0.71, 0.54, and 0.76, respectively; the specificities were 0.83, 0.77, and 0.60, respectively; and the accuracies were 0.78, 0.65, and 0.69, respectively.
    UNASSIGNED: There were statistically significant differences in age and location of lesions between the \"noninvasive\" lesion group and the invasive lesion group. The radiomics model can predict the invasiveness of lung adenocarcinoma manifesting as GGNs. There was no significant difference in MDT between \"noninvasive\" lesions and invasive lesions. The radiomics model can predict the instability of lung adenocarcinoma manifesting as GGN. When the threshold of MDT was set at 813 days, the model had higher specificity, accuracy, and diagnostic efficiency.
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