Incisional hernia

切口疝
  • 文章类型: Journal Article
    背景:造口逆转后的线性闭合(LC)与手术部位感染(SSI)的高风险相关。肠带闭合和LC对造口逆转后皮肤伤口的闭合均呈阳性,尚无法区分哪一种对患者的预后更有利。
    方法:我们在Embase进行了搜索,PubMed,WebofScience,和Cochrane图书馆,并从每个数据库开始到2024年7月进行了随机对照实验。其中,30天内的SSI,操作时间,住院时间,切口疝,和创面愈合时间均为预后指标。
    结果:本荟萃分析纳入了11项研究(荷包封堵器组506例,LC组489例)。汇总数据显示,荷包闭合组的SSI率明显低于LC组(比值比,0.15;95%置信区间,0.09-0.24;P<.00001;I2=0%)。手术时间的差异,住院时间,切口疝,创面愈合时间无统计学意义。
    结论:总体而言,与LC相比,肠袋关闭术在造口逆转后的SSI率显著较低.
    BACKGROUND: Linear closure (LC) following stoma reversal is associated with a high risk of surgical site infection (SSI). Purse-string closure and LC were both positive for the closure of the skin wound following stoma reversal, and it was not yet possible to distinguish which one was more beneficial to the patient\'s prognosis.
    METHODS: We conducted a search in Embase, PubMed, Web of Science, and Cochrane Library and conducted a randomized controlled experiment from the inception of each database to July 2024. Among them, the SSI within 30 days, operation time, hospitalization time, incisional hernia, and wound healing time were all outcome indicators.
    RESULTS: Eleven studies were included in this meta-analysis (506 patients in the purse-string closure group and 489 patients in the LC group). The pooled data showed that the SSI rate was significantly lower in the purse-string closure group than in the LC group (odds ratio, 0.15; 95% confidence interval, 0.09-0.24; P < .00001; I2 = 0%). The differences in operative time, hospitalization time, incision hernia, and wound healing time were not statistically significant.
    CONCLUSIONS: Overall, purse-string closure had a significantly lower SSI rate following stoma reversal than LC.
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  • 文章类型: Journal Article
    目的:报告膀胱切除术患者行回肠导管(IC)尿流改道行造口旁疝(PSH)修补术的围手术期和术后长期结果。
    方法:我们回顾了2003年至2022年在我们中心接受膀胱切除术和IC改道的患者。基线变量,包括PSH修复的手术方法和修复技术,被捕获。进行多变量Cox回归分析以检验不同变量与PSH复发之间的关联。
    结果:纳入36例中位年龄(IQR)为79(73-82)岁的患者。膀胱切除术至PSH修复的中位时间为30(14-49)个月。大多数PSH维修(32/36,89%)是选择性进行的,而4则是由于小肠梗阻。疝修补术通过开放进行(n=25),机器人(10),和腹腔镜方法(1)。手术技术包括用网状物直接修复(20),无网格直接修复(4),带网孔的造口重新定位(5),和没有网格的气孔定位(7)。90天并发症发生率为28%。在24(7-47)个月的中位随访中,17例(47%)患者复发。中位复发时间为9(7-24)个月。在多变量分析中,PSH修复后90天的并发症与复发风险增加相关。
    结论:在这篇关于泌尿外科文献中最大的PSH修复系列之一的报告中,47%的患者在疝修补术后复发,中位随访时间为2年。比较修复技术或使用开放或微创方法时,复发率没有显着差异。
    OBJECTIVE: To report perioperative and long-term postoperative outcomes of cystectomy patients with ileal conduit (IC) urinary diversion undergoing parastomal hernia (PSH) repair.
    METHODS: We reviewed patients who underwent cystectomy and IC diversion between 2003 and 2022 in our center. Baseline variables, including surgical approach of PSH repair and repair technique, were captured. Multivariable Cox regressionanalysis was performed to test for the associations between different variables and PSH recurrence.
    RESULTS: Thirty-six patients with a median (IQR) age of 79 (73-82) years were included. The median time between cystectomy and PSH repair was 30 (14-49) months. Most PSH repairs (32/36, 89%) were performed electively, while 4 were due to small bowel obstruction. Hernia repairs were performed through open (n=25), robotic (10), and laparoscopic approaches (1). Surgical techniques included direct repair with mesh (20), direct repair without mesh (4), stoma relocation with mesh (5), and stomarelocation without mesh (7). The 90-day complication rate was 28%. In a median follow-up of 24 (7-47) months, 17 patients (47%) had a recurrence. The median time to recurrence was 9 (7-24) months. On multivariable analysis, 90-day complication following PSH repair was associated with an increased risk of recurrence.
    CONCLUSIONS: In this report of one of the largest series of PSH repair in the Urology literature, 47% of patients had a recurrence following hernia repair with a median follow-up time of 2 years. There was no significant difference in recurrence rates when comparing repair technique or the use of open or minimally invasive approaches.
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  • 文章类型: Journal Article
    背景:最初的ROCSS试验表明,在造口闭合期间接受预防性生物网片的患者中,2年时临床可检测的切口疝显著减少。ROCSS-Ex旨在使用腹壁特定的生活质量评分来调查存活队列中网状物的5-8年成本效益。
    方法:确定了来自原始英国中心的合格参与者。使用HerQLes评分和EQ-5D-5L测量主要结果(腹壁特异性生活质量)。评估人员对患者的原始分配仍然视而不见,即使病人知道他们的治疗。
    结果:在最初的790名患者中,598人可用于长期随访。HerQLes评分可用于396例患者(无网格:191,网格:205)。两组之间的主要结局没有差异(平均差异为1.48,95%c.i.(-2.35,5.32),P=0.45),并且从长期来看,在整个队列中常规插入预防性生物网状物没有成本效益。然而,接受网片的患者在逆转后的前3年内经历了明显更少的造口部位并发症,需要更少的手术再干预(无网片组32对54;发生率为0.55,95%c.i.(0.31,0.97),P=0.04)。
    结论:ROCSS-Ex对预防性网片插入与标准修复术后5-8年腹壁特异性生活质量的影响显示出模棱两可的结果。由于大多数再干预发生在手术后的前3年内,在早期反复手术对患者影响最大的亚组中,预防性网片可能具有一定的作用.
    背景:ISRCTN25584182(http://www.clinicaltrials.gov)。
    BACKGROUND: The original ROCSS trial demonstrated a significant reduction in clinically detectable incisional hernias at 2 years in patients receiving prophylactic biological mesh during stoma closure. ROCSS-Ex was designed to investigate the 5-8-year cost-effectiveness of mesh in the surviving cohort using an abdominal wall-specific quality of life score.
    METHODS: Eligible participants from original UK centres were identified. The primary outcome (abdominal wall-specific quality of life) was measured using the HerQLes score and EQ-5D-5L. Assessors remained blind to patients\' original allocation, even if the patient was aware of their treatment.
    RESULTS: Of the original 790 patients, 598 were available for long-term follow-up. HerQLes scores were available for 396 patients (no mesh: 191, mesh: 205). There was no difference in primary outcome between the two groups (mean difference of 1.48, 95% c.i. (-2.35, 5.32), P = 0.45) and no cost benefit of routine insertion of prophylactic biological mesh across the entire cohort in the long term. However, patients who received mesh experienced significantly fewer stoma site complications within the first 3 years after reversal and needed fewer surgical reinterventions (32 versus 54 for the no mesh group; incidence rate ratio of 0.55, 95% c.i. (0.31, 0.97), P = 0.04).
    CONCLUSIONS: ROCSS-Ex has shown equivocal outcomes for prophylactic mesh insertion versus standard repair on abdominal wall-specific quality of life 5-8 years after surgery. As most reinterventions occurred within the first 3 years post-surgery, there may be a role for prophylactic mesh in a subset of patients who would be most adversely affected by repeated surgery early on.
    BACKGROUND: ISRCTN25584182 (http://www.clinicaltrials.gov).
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  • 文章类型: Journal Article
    造口旁疝(PSH)的治疗是疝手术的主要挑战。据报道,各种技术在并发症和复发率方面具有不同的结果。这项研究的目的是分享我们植入DynaMesh-IPST-R和-IPST的初步经验,由聚偏氟乙烯(PVDF)制成的腹膜内漏斗网。这是一项回顾性观察性队列研究,对2019年3月至2023年4月期间使用烟囱技术与腹膜内漏斗网眼IPST-R或IPST进行PSH治疗的患者进行了研究。主要结果是复发,次要结果是术中和术后并发症,后者使用Clavien-Dindo分类进行评估。共21例连续患者接受腹膜内PVDF漏斗网片治疗,17与IPST-R和4与IPST。术中无并发症。总的来说,61.9%(n=12)的患者无并发症发生.4例(19.0%)出现严重的术后并发症(定义为Clavien-Dindo≥3b)。在平均21.6(范围4.8-37.5)个月的随访期间,1例(4.8%)复发.总之,用于治疗造口旁疝,IPST-R或IPST网状物的植入已被证明是有效的,易于处理,而且非常安全.特别是,低复发率4.8%,这与当前的文献一致,是令人信服的。然而,更多的患者将提高结果的有效性.
    The treatment of parastomal hernias (PSH) represents a major challenge in hernia surgery. Various techniques have been reported with different outcomes in terms of complication and recurrence rates. The aim of this study is to share our initial experience with the implantation of the DynaMesh-IPST-R and -IPST, intraperitoneal funnel meshes made of polyvinylidene fluoride (PVDF). This is a retrospective observational cohort study of patients treated for PSH between March 2019 and April 2023 using the chimney technique with the intraperitoneal funnel meshes IPST-R or IPST. The primary outcome was recurrence and the secondary outcomes were intraoperative and postoperative complications, the latter assessed using the Clavien-Dindo classification. A total of 21 consecutive patients were treated with intraperitoneal PVDF funnel meshes, 17 with IPST-R and 4 with IPST. There were no intraoperative complications. Overall, no complications occurred in 61.9% (n = 12) of the patients. Major postoperative complications (defined as Clavien-Dindo ≥ 3b) were noted in four cases (19.0%). During the mean follow-up period of 21.6 (range 4.8-37.5) months, one patient (4.8%) had a recurrence. In conclusion, for the treatment of parastomal hernias, the implantation of IPST-R or IPST mesh has proven to be efficient, easy to handle, and very safe. In particular, the low recurrence rate of 4.8%, which is in line with the current literature, is convincing. However, a larger number of patients would improve the validity of the results.
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  • 文章类型: Journal Article
    目的:建立基于机器学习的永久性结肠造口术患者术后造口旁疝(PSH)风险预测模型,协助护士识别高危人群并制定预防性护理策略。
    方法:对2017年6月至2023年6月在安徽医科大学第二附属医院行永久性结肠造口的495例结直肠癌患者进行病例对照研究,随访1年。根据术后1年内的PSH发生率将患者分为PSH和非PSH组。数据分为训练(70%)和测试(30%)集。使用最小绝对收缩和选择算子(LASSO)回归进行变量选择,并利用Logistic回归(LR)建立了二元分类预测模型,支持向量分类(SVC)K近邻(KNN),随机森林(RF),轻型梯度增压机(LGBM),和极端梯度提升(XgBoost)。二进制分类标签对于PSH发生表示为1,对于没有PSH发生表示为0。通过5倍交叉验证优化参数。使用曲线下面积(AUC)评估模型性能,特异性,灵敏度,准确度,正预测值,负预测值,和F1得分。使用决策曲线分析(DCA)评估临床效用,使用Shapley加法解释(SHAP)增强了模型解释,并使用列线图实现了模型可视化。
    结果:1年内PSH的发生率为29.1%(144例患者)。在测试的模型中,RF模型显示出最高的辨别能力,AUC为0.888(95%CI:0.881-0.935),连同优越的特异性,准确度,灵敏度,F1得分。它还在DCA曲线上显示出最高的临床净效益。SHAP分析确定了与PSH风险相关的前10个影响变量:体重指数(BMI),操作持续时间,慢性阻塞性肺疾病(COPD)的病史和状态,前白蛋白,肿瘤淋巴结转移(TNM)分期,造口部位,腹直肌厚度(TRAM),C反应蛋白CRP,美国麻醉师学会身体状况分类(ASA),和气孔直径。来自SHAP图的这些见解说明了这些因素如何影响个体PSH结果。列线图用于模型可视化。
    结论:随机森林模型在预测结肠PSH方面表现出稳健的预测性能和临床相关性。该模型有助于早期识别高危患者并指导预防护理。
    OBJECTIVE: To develop a machine learning-based risk prediction model for postoperative parastomal hernia (PSH) in colorectal cancer patients undergoing permanent colostomy, assisting nurses in identifying high-risk groups and devising preventive care strategies.
    METHODS: A case-control study was conducted on 495 colorectal cancer patients who underwent permanent colostomy at the Second Affiliated Hospital of Anhui Medical University from June 2017 to June 2023, with a 1-year follow-up period. Patients were categorized into PSH and non-PSH groups based on PSH occurrence within 1-year post-operation. Data were split into training (70%) and testing (30%) sets. Variable selection was performed using Least Absolute Shrinkage and Selection Operator (LASSO) regression, and binary classification prediction models were established using Logistic Regression (LR), Support Vector Classification (SVC), K Nearest Neighbor (KNN), Random Forest (RF), Light Gradient Boosting Machine (LGBM), and Extreme Gradient Boosting (XgBoost). The binary classification label denoted 1 for PSH occurrence and 0 for no PSH occurrence. Parameters were optimized via 5-fold cross-validation. Model performance was evaluated using Area Under Curve (AUC), specificity, sensitivity, accuracy, positive predictive value, negative predictive value, and F1-score. Clinical utility was evaluated using decision curve analysis (DCA), model explanation was enhanced using shapley additive explanation (SHAP), and model visualization was achieved using a nomogram.
    RESULTS: The incidence of PSH within 1 year was 29.1% (144 patients). Among the models tested, the RF model demonstrated the highest discrimination capability with an AUC of 0.888 (95% CI: 0.881-0.935), along with superior specificity, accuracy, sensitivity, and F1 score. It also showed the highest clinical net benefit on the DCA curve. SHAP analysis identified the top 10 influential variables associated with PSH risk: body mass index (BMI), operation duration, history and status of chronic obstructive pulmonary disease (COPD), prealbumin, tumor node metastasis (TNM) staging, stoma site, thickness of rectus abdominis muscle (TRAM), C-reactive protein CRP, american society of anesthesiologists physical status classification (ASA), and stoma diameter. These insights from SHAP plots illustrated how these factors influence individual PSH outcomes. The nomogram was used for model visualization.
    CONCLUSIONS: The Random Forest model demonstrated robust predictive performance and clinical relevance in forecasting colonic PSH. This model aids in early identification of high-risk patients and guides preventive care.
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  • 文章类型: Journal Article
    目的:疝登记处报告说,一般外科医师并不总是实施指南,并建议在疝专科中心该手术的成功率更高。疝气中心有很多定义,但是他们的目标包括通过使临床实践均匀化来改善医疗保健。我们进行了系统评价和荟萃分析,以分析疝气中心的定义,并将疝气中心与非专科中心进行比较。材料和方法:CochraneCentral,Scopus,Scielo,和PubMed进行了系统搜索,寻找定义疝气中心或比较疝气中心和非专业中心的研究.评估的结果是复发,手术部位事件,住院时间(LOS),和手术时间。我们进行了疝类型的亚组分析。用RStudio进行统计学分析。结果:筛选了3,260项研究,彻底审查了88项。共纳入13项研究。五项研究定义了疝气中心和八项研究,包括141,366名患者,将疝气中心与非专业中心进行了比较。一般来说,这些定义在决策和教育要求上相似,但在结构方面和认证所需的步骤上有所不同。我们发现腹股沟疝中心的复发率较低(1.08%vs.5.11%;RR0.21;95%CI0.19至0.23;p<0.001)和腹侧疝(3.2%vs.8.9%;RR0.425;95%CI0.28至0.64;p<0.001)。疝中心的腹侧手术部位感染也较低(4.3%vs.11.9%;RR0.435;95%CI0.21至0.90;p=0.026)和腹股沟(0.1%与0.52%;RR0.15;95%CI0.02至0.99;p=0.49)修复。结论:我们的系统评价和荟萃分析支持建立疝气中心可以改善术后结局数据。系统审查注册:https://www。crd.约克。AC.uk/prospro/display_record.php?ID=CRD42024522263,PROSPEROCRD42024522263。
    Aim: Hernia registries report that guidelines are not always implemented by general surgeons and suggest that the success rate of this procedure is higher in hernia specialty centers. There are many definitions of hernia centers, but their objectives consist of improving healthcare by homogenizing the clinical practice. We performed a systematic review and meta-analysis to analyze hernia centers\' definitions and compare hernia centers with non-specialized centers. Material and Methods: Cochrane Central, Scopus, Scielo, and PubMed were systematically searched for studies defining a hernia center or comparing hernia centers and non-specialized centers. Outcomes assessed were recurrence, surgical site events, hospital length of stay (LOS), and operative time. We performed subgroup analyses of hernia type. Statistical analysis was performed with R Studio. Results: 3,260 studies were screened and 88 were thoroughly reviewed. Thirteen studies were included. Five studies defined a hernia center and eight studies, comprising 141,366 patients, compared a hernia center with a non-specialized center. Generally, the definitions were similar in decision-making and educational requirements but differed in structural aspects and the steps required for the certification. We found lower recurrence rates for hernia centers for both inguinal (1.08% versus 5.11%; RR 0.21; 95% CI 0.19 to 0.23; p < 0.001) and ventral hernia (3.2% vs. 8.9%; RR 0.425; 95% CI 0.28 to 0.64; p < 0.001). Hernia centers also presented lower surgical site infection for both ventral (4.3% vs. 11.9%; RR 0.435; 95% CI 0.21 to 0.90; p = 0.026) and inguinal (0.1% vs. 0.52%; RR 0.15; 95% CI 0.02 to 0.99; p = 0.49) repair. Conclusion: Our systematic review and meta-analysis support that a hernia center establishment improves postoperative outcomes data. Systematic Review Registration: https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42024522263, PROSPERO CRD42024522263.
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  • 文章类型: Editorial
    在微创外科手术中,结直肠手术与切口疝(IH)的发生率明显较高有关,1.7%至24.3%不等。这种并发症每年都会给医疗保健系统带来巨大的负担,需要外科医生的紧急关注。在《世界胃肠外科杂志》上发表的一项研究中,Fan等人比较了1614例不同部位行腹腔镜结直肠手术患者IH的发生率,并评估了与其发生相关的危险因素。这篇社论分析了腹腔镜结直肠手术后IH的当前危险因素,强调肥胖的影响,手术部位感染,以及切口位置的选择对其发展的影响。此外,我们总结了目前可用的IH预防措施。鉴于与IH相关的低手术修复率和高复发率,与治疗相比,预防值得更多的研究和关注。
    Among minimally invasive surgical procedures, colorectal surgery is associated with a notably higher incidence of incisional hernia (IH), ranging from 1.7% to 24.3%. This complication poses a significant burden on the healthcare system annually, necessitating urgent attention from surgeons. In a study published in the World Journal of Gastrointestinal Surgery, Fan et al compared the incidence of IH among 1614 patients who underwent laparoscopic colorectal surgery with different extraction site locations and evaluated the risk factors associated with its occurrence. This editorial analyzes the current risk factors for IH after laparoscopic colorectal surgery, emphasizing the impact of obesity, surgical site infection, and the choice of incision location on its development. Furthermore, we summarize the currently available preventive measures for IH. Given the low surgical repair rate and high recurrence rate associated with IH, prevention deserves greater research and attention compared to treatment.
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  • 文章类型: Case Reports
    切口疝是指先前手术切口部位的腹壁缺损。在本文中,我们描述了两名患者,他们在几年前曾接受过开放性肾结石手术,并且患有同侧复发性结石。他们都通过微型经皮肾镜碎石术(PCNL)治疗肾结石。病例1是一名50岁的女性,在开放手术5年后患有右侧复发性鹿角结石,需要两次PCNL手术才能达到无石状态。病例2是一名74岁的男性,有明显的合并症,在10年的开放性肾镜取石术后,患有右27毫米复发性肾结石。两名患者在PCNL术后均无并发症。这些病例表明,在腰椎切口瘢痕疝的病例中,具有超声引导和正确患者定位的微型PCNL可能是肾结石治疗的最佳方法。
    Incisional hernia refers to an abdominal wall defect at the site of a previous surgical incision. In this paper, we describe two patients who previously underwent open kidney stone surgery several years ago and had the ipsilateral recurrent stones. They were both managed by a mini percutaneous nephrolithotripsy (PCNL) to treat kidney stones. Case 1 was a 50-year-old female with right recurrent staghorn stones after 5 years of open surgery and required two PCNL procedures to achieve stone-free status. Case 2 was a 74-year-old male with significant comorbidities who had a right 27 mm recurrent kidney stone after 10 years of open nephrolithotomy. Both patients experienced no postoperative complications after PCNL. These cases show that in cases of lumbar incisional scar hernias, mini PCNL with ultrasound guidance and proper patient positioning can be an optimal approach for kidney stone treatment.
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  • 文章类型: Journal Article
    我们的研究解决了腹侧疝修补术文献中的空白,关于机器人经腹直肌后脐假体修复(r-TARUP)治疗原发性和切口腹侧疝的长期有效性。本研究旨在报告3年复发率和总体患者预后,包括生活质量。
    对2018年8月至2022年1月的101例择期r-TARUP患者进行前瞻性收集数据的回顾性分析。收集的数据包括人口统计,疝气大小,网格类型,术后结局和手术前后的欧洲疝学会生活质量问卷(EuraHS-QoL)。
    该组患者的平均年龄为53岁,平均体重指数(BMI)为32kg/m,54%的切口疝和46%的原发性疝,平均长度和宽度分别为4.4厘米和6.1厘米,利用合成的58%和生物可吸收的42%网眼类型。大多数被归类为疾病控制和预防中心(CDC)一级伤口。术后并发症包括血清肿(2%),血肿(3%),这需要手术干预,与网格类型没有显著相关性。腹横肌释放(TAR)与住院时间增加之间存在强正相关(相关系数:0.731,p<0.001)。与术后3年的评估相比,术前生活质量评估显示出统计学上的显着改善。平均值(±SD)为61.61±5.29与13.84±2.6(p<0.001)。平均随访34.4个月,1年无疝气复发,2-3年随访3次复发(3.2%)。
    r-TARUP技术已被证明对修复原发性和切口腹侧疝是安全有效的,随访期间复发率低,生活质量(QoL)明显改善。
    UNASSIGNED: Our study addresses the gap in ventral hernia repair literature, regarding the long-term effectiveness of robotic transabdominal retrorectus umbilical prosthetic repair (r-TARUP) for primary and incisional ventral hernias. This study aimed to report the 3-year recurrence rates and overall patient outcomes including quality of life.
    UNASSIGNED: A retrospective review of prospective collected data analyzed 101 elective r-TARUP patients from August 2018 to January 2022. Data collected included demographics, hernia sizes, mesh types, postoperative outcomes and the European Hernia Society Quality of Life questionnaire (EuraHS-QoL) before and after surgery.
    UNASSIGNED: The average age of the group of patients was 53, having a mean body mass index (BMI) of 32 kg/m, with 54% incisional and 46% primary hernias, with mean length and width of 4.4 cm and 6.1 cm, utilizing synthetic 58% and bioabsorbable 42% mesh types. The majority were classified as Centers of Disease Control and Prevention (CDC) class I wounds. Postoperative complications included seroma (2%), hematoma (3%), which required surgical intervention, with no significant correlation to mesh type. A strong positive correlation was found between Transversus Abdominis Release (TAR) and increased length of hospital stay (correlation coefficient: 0.731, p < 0.001). Preoperative quality of life assessments demonstrated statistically significant improvements when compared to postoperative assessments at 3 years, with a mean (±SD) of 61.61 ± 5.29 vs. 13.84 ± 2.6 (p < 0.001). Mean follow up of 34.4 months with no hernia recurrence at 1 year and 3 recurrence at the 2-3 years follow up (3.2%).
    UNASSIGNED: The r-TARUP technique has proven to be safe and effective for repairing primary and incisional ventral hernias, with a low recurrence rate during this follow up period with a noticeable improvement in quality of life (QoL).
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