未经授权:腹股沟疝是一种常见的外科疾病。一旦被监禁或勒死,它可能危及病人的生命。因此,研究嵌顿性腹股沟疝(IIH)和绞窄性腹股沟疝(SIH)的危险因素至关重要。IIH和SIH的严重并发症之一是肠坏死,这是由于血液供应障碍而发生的。本研究探讨肠切除的危险因素,建立简单模型评估肠切除的发生率,为临床工作提供重要帮助和有限指导。
UNASSIGNED:我们的研究小组收集并回顾性分析了2008年9月至2016年12月在温州医科大学附属第一医院住院的338例IIH患者的临床资料。根据手术计划,我们将纳入的病例分为两组,非肠和肠切除组,并对这些组的临床病例特征进行统计分析。
UNASSIGNED:基于多变量逻辑回归分析,我们发现,在老年人(≥70岁)中,肠切除风险增加是高度相关的,对于高温(≥37.3°C)的人,高全身免疫炎症指数(SII)值(≥1230.13),肠梗阻的存在,和腹膜炎的迹象。Further,我们使用特殊软件处理了5个独立的风险因素,得到了一个简单的模型,称为列线图。为了验证列线图的准确性和预测能力,我们计算C指数:0.806,并使用校准曲线来评估其稳定性和预测性能。我们构建了ROC曲线列线图和其他子变量,并计算对应于列线图的曲线下面积(AUC)(AUC=0.808,95%CI=0.762至0.848),SII(AUC=0.752,95%CI=0.703至0.797),年龄(AUC=0.641,95%CI=0.587至0.692),温度(AUC=0.579,95%CI=0.524至0.632),肠梗阻(AUC=0.685,95%CI=0.633至0.734),和腹膜炎的迹象(AUC=0.580,95%CI=0.525至0.633)。
UNASSIGNED:可以说,我们首次发现,诸如SII之类的临床变量是IIH的阑尾切除术的独立危险因素。基于SII和其他变量的列线图可以准确且容易地预测IIH需要肠切除的概率。
UNASSIGNED: An inguinal hernia is a common surgical disease. Once incarcerated or strangulated, it may endanger the life of the patient. Therefore, it is essential to study the risk factors of incarcerated inguinal hernia (IIH) and strangulated inguinal hernia (SIH). One of the serious complications of IIH and SIH is intestinal necrosis, which occurs owing to blood supply disorder. The study explores the risk factors of intestinal resection and establishes a simple model to assess the incidence of intestinal resection to provide significant assistance and limited guidance for clinical work.
UNASSIGNED: Our research team collected and retrospectively analysed the clinical data of 338 patients with IIH who were hospitalized in the First Affiliated Hospital of Wenzhou Medical University between September 2008 and December 2016. According to the surgical plan, we divided the included cases into two groups, non-intestinal and intestinal resection groups, and the clinical case characteristics of these groups were statistically analysed.
UNASSIGNED: Based on multivariable logistic regression analysis, we found that increased risk of bowel resection was highly correlated among the elderly (≥70 years), and for people with high temperature (≥37.3°C), high systemic immune-inflammation index(SII) values (≥1230.13), presence of bowel obstruction, and signs of peritonitis. Further, we processed the five independent risk factors using special software to obtain a simple model called a nomogram. To verify the nomogram\'s accuracy and predictive ability, we calculate the C-index: 0.806 and use the calibration curve to evaluate its stability and predictive performance. We constructed the ROC curve nomogram and other sub-variables, and calculated the area under the curve (AUC) corresponding to the nomogram (AUC = 0.808, 95% CI = 0.762 to 0.848), SII (AUC = 0.752, 95% CI = 0.703 to 0.797), age (AUC = 0.641, 95% CI = 0.587 to 0.692), temperature (AUC = 0.579, 95% CI = 0.524 to 0.632), bowel obstruction (AUC = 0.685, 95% CI = 0.633 to 0.734), and signs of peritonitis (AUC = 0.580, 95% CI = 0.525 to 0.633).
UNASSIGNED: It can be said that we found for the first time that clinical variables such as SII are independent risk factors for enterectomy for IIH. The nomogram based on SII and other variables can accurately and easily predict the probability of IIH requiring bowel resection.