Fractura

Fractura
  • 文章类型: Journal Article
    由于尿毒症的附加因素,慢性肾脏病患者的骨折风险高于普通人群。尽管尿毒症相关骨折背后的机制尚未完全了解,骨矿物质含量的减少和骨结构的改变都会增加骨脆性,这一点已被广泛接受。随着慢性肾病的进展,骨折的风险增加,尤其是一旦病人需要透析.风险增加的许多原因包括高龄,闭经,类固醇暴露,维生素D减少,PTH增加,营养不良和慢性炎症。血清磷,无论是高还是非常低,似乎与骨折的风险有关.此外,已知血清磷酸盐增加通过旨在预防高磷酸盐血症的适应性激素机制的发展直接和间接影响骨代谢,如PTH和FGF23的增加和骨化三醇的减少。如果使用磷捕获器减少肠道对磷的吸收,这些适应性机制就不那么强烈。这似乎对降低骨折风险有积极影响。我们在这里描述了与血清磷水平相关的可能机制,肾脏疾病中典型的适应性机制以及使用药物控制高磷酸盐血症和骨折风险。我们发现文献中没有研究提供不同治疗方法对慢性肾脏病患者骨折风险影响的证据。我们建议控制磷应该是一个需要考虑的目标。
    Patients with chronic kidney disease have a higher risk of fractures than the general population due to the added factor of uraemia. Although the mechanisms behind uraemia-associated fractures are not fully understood, it is widely accepted that the decrease in bone mineral content and alteration in bone architecture both increase bone fragility. As chronic kidney disease progresses, the risk of fracture increases, especially once the patient requires dialysis. Among the many causes of the increased risk are advanced age, amenorrhoea, steroid exposure, decreased vitamin D, increased PTH, malnutrition and chronic inflammation. Serum phosphorus, whether high or very low, seems to correlate with the risk of fracture. Moreover, increased serum phosphate is known to directly and indirectly affect bone metabolism through the development of adaptive hormonal mechanisms aimed at preventing hyperphosphataemia, such as the increase in PTH and FGF23 and the reduction in calcitriol. These adaptive mechanisms are less intense if the intestinal absorption of phosphorus is reduced with the use of phosphorus captors, which seem to have a positive impact in reducing the risk of fractures. We describe here the possible mechanisms associating serum phosphorus levels, the adaptive mechanisms typical in kidney disease and the use of drugs to control hyperphosphataemia with the risk of fractures. We found no studies in the literature providing evidence on the influence of different treatments on the risk of fractures in patients with chronic kidney disease. We suggest that control of phosphorus should be an objective to consider.
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  • 文章类型: Journal Article
    背景:桡骨远端骨折(DRF)正在成为卫生资源的更大负担,因为我们的人口统计和管理策略不断发生变化,所以准确的流行病学理解是必须的。我们提出了一项DRF流行病学研究,并将其与伊比利亚半岛和欧洲的其他卫生地区进行了比较。
    方法:在2017年至2018年期间在我们卫生领域登记的18岁以上患者的每个DRF都是观察性的,并使用AO-OTA分类进行回顾性记录和分类。年龄,性别,一年的季节,损伤机制,分析了相关损伤的存在和治疗类型。
    结果:1,108例患者的1,121DRF,903名女性(81.5%)和205名男性(18.5%),已注册。左侧受累612例(54.6%),右侧受累509例(45.4%)。我们样本的平均年龄为65.9岁(CI95%:65-67.9岁)。我们人群中DRF的发生率为每100,000人年158.5骨折;49.2%被分类为AO-OTA分类的A型,19%被手术治疗。
    结论:DRF的发病率在男性和女性六十岁时最高。AO-OTA分类的A型骨折最常见。大部分骨折非手术治疗。通常接受手术治疗的患者是一名妇女,超过50岁的桡骨远端关节内复杂骨折。
    BACKGROUND: Distal radius fractures (DRF) are being a bigger burden for health resources as changes continue to happen in our population demography and in management strategies, so a precise epidemiologic comprehension is mandatory. We present a DRF epidemiology study and we compared it with other sanitary areas of the Iberian Peninsula and Europe.
    METHODS: Every DRF in our sanitary area registered between 2017 and 2018 in patients older than 18 years old were observational and retrospectively recorded and classified using AO-OTA classification. Age, sex, season of the year, mechanism of injury, presence of associated injuries and type of treatment were analysed.
    RESULTS: 1,121 DRF in 1,108 patients, 903 women (81.5%) and 205 men (18.5%), were registered. Left side was affected in 612 cases (54.6%) and right side in 509 cases (45.4%). The average age of our sample was 65.9 years old (CI95%: 65-67.9 years old). The incidence rate of DRF in our population was 158.5 fractures per 100,000 people-year; 49.2% were classified as type A of AO-OTA classification and 19% were treated surgically.
    CONCLUSIONS: Incidence of DRF had a maximum during males and women sixth decade of age. Type A fractures of AO-OTA classification were the most frequent. Most part of the fractures were treated non-surgically. The usual patient treated surgically was a woman, over 50 years old with a distal radius intraarticular complex fracture.
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  • 文章类型: Journal Article
    背景:预期寿命提高了,导致脆性患者髋臼骨折增加。带加固笼的全髋关节置换术是一种技术上复杂的选择,但允许骨折控制和早期动员。我们的目的是评估在髋臼骨折的脆性患者中使用Burch-Schneider笼是否可以立即稳定负荷,而不会威胁到关节成形术的早期生存。
    方法:对一系列14例髋臼骨折患者进行描述性研究,这些患者通过与自体骨移植和骨水泥髋臼杯相关的加固笼治疗,动员和承受。JudetLetournel骨折类型,手术延迟,并对入院期间并发症进行分析。出院后,我们根据Gie的分类记录了移植物的掺入情况,根据布鲁克的说法,钙化的存在,骨折的固结,根据HHS和MerléD\'AubignéPostel评分,植入物松动和功能方面。
    结果:最常见的骨折是两列(6/14),手术延迟平均为11天,住院时间为21,5天。一名患者在手术后死亡。平均随访时间为34.4个月。所有骨折均已愈合,并且在所有情况下都合并了骨移植物。平均HHS为82分,Merle评分为15/18。无与关节置换相关的并发症。
    结论:在骨移植上使用Burch-Schneider固定支架进行全髋关节置换术,不增加骨连接是治疗所有类型的髋臼骨折的好选择。
    BACKGROUND: Life expectancy has risen, leading to an increase in acetabular fractures in fragile patients. Total hip arthroplasty with a reinforcement cage is a technically complex option, but allows fracture control and early mobilization. Our aim is to assess whether the use of Burch-Schneider cage in fragile patients with acetabular fractures allows immediate load stabilization without threatening the early survival of the arthroplasty.
    METHODS: Descriptive study of a series of 14 patients with acetabular fractures treated by a reinforcement cage associated with autologous bonegraft plus a cemented acetabular cup, and mobilization and bearing. Judet Letournel fracture types, surgical delay, and complications during admission were analyzed. Following hospital discharge we recorded the incorporation of grafts according to Gie\'s classification, presence of calcifications according to Brooker, consolidation of the fracture, loosening of implants and functional aspects according to the HHS and Merlé D\'Aubigné Postel score.
    RESULTS: The most common fracture was both columns (6/14), with a surgical delay being of 11 days mean and 21,5 days of length of stay. One patient died after surgery. The mean follow-up was 34.4 months. All fractures healed and the bonegraft was incorporated in all cases. The mean HHS was 82 points and the Merle Score was 15/18. There were no complications related to arthroplasty.
    CONCLUSIONS: Total hip arthroplasty with Burch-Schneider cage on bonegraft and no added osteosynthesis is a good option of treatment of all types of displaced acetabular fractures in a fragile patient.
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  • 文章类型: Journal Article
    Patients with chronic kidney disease have a higher risk of fractures than the general population due to the added factor of uraemia. Although the mechanisms behind uraemia-associated fractures are not fully understood, it is widely accepted that the decrease in bone mineral content and alteration in bone architecture both increase bone fragility. As chronic kidney disease progresses, the risk of fracture increases, especially once the patient requires dialysis. Among the many causes of the increased risk are advanced age, amenorrhoea, steroid exposure, decreased vitamin D, increased parathyroid hormone (PTH), malnutrition and chronic inflammation. Serum phosphorus, whether high or very low, seems to correlate with the risk of fracture. Moreover, increased serum phosphate is known to directly and indirectly affect bone metabolism through the development of adaptive hormonal mechanisms aimed at preventing hyperphosphataemia, such as the increase in PTH and fibroblast growth factor 23 (FGF23) and the reduction in calcitriol. These adaptive mechanisms are less intense if the intestinal absorption of phosphorus is reduced with the use of phosphorus captors, which seem to have a positive impact in reducing the risk of fractures. We describe here the possible mechanisms associating serum phosphorus levels, the adaptive mechanisms typical in kidney disease and the use of drugs to control hyperphosphataemia with the risk of fractures. We found no studies in the literature providing evidence on the influence of different treatments on the risk of fractures in patients with chronic kidney disease. We suggest that control of phosphorus should be an objective to consider.
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  • 文章类型: Journal Article
    BACKGROUND: Hip fracture is a very frequent traumatic pathology in the elderly with high mortality. Different factors have been associated with mortality after surgery (age comorbidities). There are surgical factors that are associated with mortality, but they have not been related to the different mortality rates and medical comorbidities.
    OBJECTIVE: To analyze the surgical parameters with influence on mortality in surgery of extracapsular hip fractures in the elderly patient, as well as the influence of medical comorbidities of these patients on mortality, by means of the Charlson comorbidity index (CCI).
    METHODS: Retrospective review of 187 patients operated on in 2015. Data were collected on age and sex, laterality and type of fracture; surgical delay, surgical time, type of osteosynthesis material, mean stay. The presence of comorbidities was determined using the JRC.
    RESULTS: Mean age was 85 years. Regarding the Charlson comorbidity index in brief, 67.4% of patients had a score between 0 and 1, 23.5% of 2, and 9.1% >2. Mortality at one month and one year after surgery was 5.3% and 14.4% respectively. Forty-three complications were recorded, of which 31 were medical complications. Of the 27 patients who died in the first year, 14 (51.8%) suffered complications, 48.2% of which were medical complications.
    CONCLUSIONS: Multivariate analysis showed significant differences with respect to age, medical complications and Charlson index abbreviated to 2 with respect to mortality. There is no association between delay and surgical time with increased mortality.
    CONCLUSIONS: No association was demonstrated between the surgical parameters studied (surgical delay and time, fracture pattern and stability, reduction criteria, surgical complications) and increased short and long-term mortality. Patients with older age, comorbidities measured with abbreviated CCI and those suffering medical complications have a higher risk of mortality at the month and year of surgery.
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  • 文章类型: Journal Article
    Sternal fractures are considered uncommon in pediatric patients. Classically, they have been described as fractures secondary to high-energy trauma that have a risk of associated lesions.
    OBJECTIVE: To describe the clinical and imaging features of sternal fractures in patients less than 18 years of age.
    METHODS: We retrospectively reviewed 79 pediatric patients diagnosed with sternal fractures after trauma.
    RESULTS: We found that 92.4% of the fractures were caused by low-energy trauma and that associated lesions were present in only 3 (4%) patients.
    CONCLUSIONS: Our results suggest that sternal fractures in children are often due to lesser trauma and that associated lesions are rare.
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  • 文章类型: Journal Article
    Osteoporosis is a systemic skeletal disease characterized by low bone mass and/or microarchitectural deterioration of bone. Osteoporosis is a risk factor for fractures specially in patients with advanced COPD. The aim of this cross-sectional study was to determine the frequency of osteoporosis and vertebral fracture in COPD patients.
    We evaluated 91 COPD patients and compared to 82 healthy subjects (control group) matched for gender and age. We measured the bone mineral density by means of dual energy X-ray absorptiometry (DXA), evaluating the lumbar vertebra (L1-L4), proximal femur and total femur and evaluated vertebral fractures in thoracic and lumbar spine using X-ray. We questioned patients whether they had had any fall that resulted in any fracture in the past five years.
    Males comprised 60.4% of COPD group and 57.3% of the control group. Mean age was 66.2±9.2 years for COPD group and 64.2±8.8 for the control group. The frequency of osteoporosis in the COPD group was 29.7% and 18.3% in control group (p=0.007). The frequency of vertebral fractures was 18.6% in the COPD group and 9.0% in control group (p=0.06). The frequency of reported falls at resulting in any fracture was 36.3% in the COPD group and 7.3% in control group (p=0.001).
    Our data indicate that COPD patients present a high frequency of osteoporosis and falls seem to be an important factor for vertebral fracture.
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  • 文章类型: Journal Article
    OBJECTIVE: To update the recommendations on osteoporosis (OP) of the Spanish Society of Rheumatology (SER) based on the best possible evidence.
    METHODS: A panel of nine expert rheumatologists in OP was created, previously selected by the SER through an open call. The phases of the work were: identification of the key areas for updating the previous consensus, analysis and synthesis of the scientific evidence (using the SIGN levels of evidence) and formulation of recommendations based on this evidence and consensus techniques.
    RESULTS: This revision of the recommendations implies an update in the diagnostic evaluation and treatment of OP. It proposes some criteria to consider the high risk of fracture and some indications to start treatment. The recommendations also address issues related to the safety of treatments and the management of special situations such as inflammatory diseases and treatment with glucocorticoids.
    CONCLUSIONS: We present an update of SER recommendations on OP.
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  • 文章类型: Journal Article
    背景:老年患者的髋臼骨折提出了治疗挑战,因为它们的骨合成可能会受到粉碎和骨骼质量差的阻碍。在某些情况下,一个很好的解决方案是通过直接前入路进行急性全髋关节置换术(THA),有或没有最小的相关骨合成。这项研究的目的是建立适应症并评估临床/功能,放射学结果和并发症,在短期和中期,髋臼骨折后使用前路手术治疗急性THA。
    方法:我们分析了15名患者收集的人口统计学数据,骨折的分类,手术数据,临床/功能和进化影像学评估,以及围手术期并发症。
    结果:患者的平均随访时间为40个月,Harris髋关节评分的最终功能评估为96.5,和MerleD'Aubigné在93%的优秀。放射学控制令人满意,没有假体松动。只有2例患者出现低度异位钙化。94%的患者术后恢复最佳,立即加载。只有一人死亡,原因与手术无关。
    结论:鉴于某些髋臼骨折,急性THA采用仰卧位直接前入路,并在范围控制下使用翻修杯和相关的最小接骨术,如有必要,促进充分的骨折稳定,患者的功能恢复与立即负荷和良好的结果,在短期和中期的并发症最少。
    BACKGROUND: Acetabular fractures in elderly patients present a therapeutic challenge, since their osteosynthesis may be hindered by comminution and poor bone quality. In certain cases, a good solution is acute total hip arthroplasty (THA) by direct anterior approach with or without minimal associated osteosynthesis. The objective of this study was to establish the indications and evaluate the clinical/functional, radiological results and complications, in the short and medium term, of acute THA using an anterior approach after acetabular fractures.
    METHODS: We analyzed 15 patients collecting: demographic data, classification of fractures, surgical data, clinical/functional and evolutionary radiographic evaluation, together with perioperative complications.
    RESULTS: The mean follow-up of the patients was 40 months with a final functional assessment of 96.5 for Harris Hip Score, and Merle D\'Aubigné excellent in 93%. The radiological controls were satisfactory without prosthetic loosening. Only 2patients presented low-grade heterotopic calcifications. Ninety-four percent of the patients presented optimal postoperative recovery, with immediate loading. There was only one death for reasons unrelated to the surgery.
    CONCLUSIONS: Given certain acetabular fractures, acute THA using a direct anterior approach in the supine position and under scope control with a revision cup plus associated minimal osteosynthesis, if necessary, facilitates adequate fracture stabilization with full functional recovery of the patient with immediate loading and excellent results in the short and medium term with minimal complications.
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  • 文章类型: Journal Article
    目标:脊髓灰质炎后患者存在诸如骨骼小而变形等问题,有狭窄的髓内管和骨质疏松症,影响手术治疗。本文的目的是描述该人群骨折手术治疗的主要术前和术中并发症。
    方法:对1995年至2014年进行了回顾性分析。从医疗记录中获得的数据包括患者年龄,断裂模式(AO/OTA),使用的设备,与标准程序相比,手术的技术方面发生了变化,以及术中骨骼并发症的存在。
    结果:64例78例骨折患者被纳入研究。47%的骨折位于股骨近端。髋关节置换术(14例)的主要并发症是髋关节外展肌缺失和术中不稳定(3),杯固定不良(3)和术中假体周围骨折(2)。髓内钉的主要问题是由于狭窄的管道和先前的骨畸形。电镀时报告的主要问题包括难以安装预成型板,和超大的硬件。
    结论:考虑到大量的术中并发症,在术前计划中,我们必须包括小直径和长度的指甲,锁定板和外部固定器,and,在髋关节置换术的情况下,细长的茎和限制性或双活动髋臼系统。
    OBJECTIVE: Post-polio patients present problems such as small and deformed bones, with narrow intramedullary canal and osteoporosis, affecting surgical treatment. The aim of this article is to describe the main preoperative and intraoperative complications of the surgical treatment of fractures in this population.
    METHODS: A retrospective analysis was conducted between 1995 and 2014. Data obtained from the medical records included patient age, fracture pattern (AO/OTA), device used, technical aspects of the surgery that changed compared to a standard procedure, and the presence of intraoperative skeletal complications.
    RESULTS: Sixty-four patients with 78 fractures were included in the study. Forty-seven percent of the fractures were at the proximal femur. The main complications of hip arthroplasty (14 patients) were absent hip abductors and intraoperative instability (3), bad cup fixation (3) and intraoperative periprosthetic fracture (2). The main problems of intramedullary nailing were due to a narrow canal and previous bone deformity. Main problems reported when plating included difficulty to fit a precontoured plate, and oversized hardware.
    CONCLUSIONS: Given the large number of intraoperative complications, in preoperative planning we must include nails of small diameter and length, locking plates and external fixators, and, in the case of hip arthroplasty, long and thin stems and restrictive or dual mobility acetabular systems.
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