背景:足部问题可能会对类风湿关节炎(RA)患者的活动性产生实质性的负面影响。它们影响步行和执行日常任务的功能能力。
方法:本研究纳入61例RA和足部疼痛或肿胀患者。研究组包括37例(年龄54.3±9.5岁)足部病变患者,如超声波所示,对照组为24例(年龄57.3±11.5岁),无足部病变。患者的健康状况用足部功能指数修订的简表(FFI-RS)进行评估,波兰版健康评估问卷-残疾指数(HAQ-DI),和疾病活动评分28(DAS28)。
结果:FFI-RS显示研究组和对照组的总结果有显著差异,以及疼痛和僵硬分量表。随后的分析显示出许多显着的相关性。FFI-RS总结果与HAQ站起来相关,走路,和总结果。FFI-RS疼痛结果与社会问题和HAQ的总结果相关。FFI-RS难度结果与病程相关。在研究小组中,FFI-RS刚度存在显著相关性,困难,和社会问题的结果是HAQ站起来,走路,和总结果,以及FFI-RS活性限制结果与HAQ的站立结果。在对照组中,FFI-RS刚度存在相关性,困难,和活动限制结果与HAQ的步行和总结果。最后,在研究小组中,我们还发现了FFI-RS总数的相关性,疼痛,刚度,困难,和社会问题结果与视觉模拟量表(VAS)结果,以及FFI-RS总结果和DAS28结果。
结论:FFI-RS是评估RA患者功能状态的有效工具,可用于评估治疗效果。FFI-RS检测无足部病变患者与RA相关的足部关节功能变化,通过超声波评估。
BACKGROUND: Foot problems may have a substantial negative impact on rheumatoid arthritis (RA) patients\' mobility. They affect walking and the functional capacity to perform daily tasks.
METHODS: This study included 61 patients with RA and foot pain or swelling. The study group comprised 37 patients (aged 54.3 ± 9.5 years) with foot lesions, as demonstrated in an ultrasound, and the control group comprised 24 patients (aged 57.3 ± 11.5 years) without foot lesions. The patients\' health statuses were evaluated with the Foot Function Index-Revised Short Form (
FFI-RS), the Polish version of the Health Assessment Questionnaire-Disability Index (HAQ-DI), and the Disease Activity Score 28 (DAS 28).
RESULTS: The
FFI-RS showed significant differences between the study and control groups in total results, as well as in the pain and stiffness subscales. Subsequent analyses showed numerous significant correlations. The
FFI-RS total results correlated with the HAQ\'s standing up, walking, and total results. The
FFI-RS pain results correlated with the social issues and HAQ\'s total results. The
FFI-RS difficulty results correlated with the disease\'s duration. In the study group, there were significant correlations of the FFI-RS stiffness, difficulty, and social issues results with the HAQ\'s standing up, walking, and total results, and also of the FFI-RS activity limitation results with the HAQ\'s standing up results. In the control group, there were correlations of the FFI-RS stiffness, difficulty, and activity limitation results with the HAQ\'s walking and total results. Finally, in the study group, we also found correlations of the FFI-RS total, pain, stiffness, difficulty, and social issues results with the Visual Analog Scale (VAS) results, as well as of the FFI-RS total results with the DAS 28 results.
CONCLUSIONS: The FFI-RS is an effective tool for assessing RA patients\' functional status and can be used to evaluate treatment effects. The FFI-RS detected RA-related changes in the foot joint function in patients without foot lesions, as assessed by ultrasound.