Closure

闭合
  • 文章类型: Case Reports
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  • 文章类型: Journal Article
    探讨腓骨游离皮瓣(FFF)梭形设计的皮肤桨闭合和重建颌面部软缺损的可行性。
    将50例接受FFF重建颌面部软缺损的患者分为两组。梭形组(20例)使用FFF中的梭形设计的皮肤桨(皮肤桨宽度小于2厘米)进行治疗,腿部伤口用初级缝合闭合。通过折叠梭形皮肤桨实现颌面部软缺损的重建或死腔的填充。常规组(30例)使用常规设计的皮肤桨(皮肤桨宽度不小于2.5cm)进行治疗。腿部伤口用床垫缝合或植皮闭合,同时通过常规方法重建颌面部软缺损或填充死腔。术后平均住院时间,腿部伤口愈合时间,术后并发症记录在术后至少6个月.
    与传统方法相比,梭形设计的皮肤桨减少了腿部伤口的平均愈合时间(梭形组:11.05天,常规组:14.77天,P<0.05)。梭形组的平均长宽比明显大于常规组(梭形组:5.85,常规组:2.93,P<0.05)。两组皮肤桨的移植物大小无差异(梭形组:23.13,常规组:27.13,P>0.05)。常规组的腿部伤口术后早期并发症高于梭形组(梭形组:0%,常规组:6.67%),而两组间供区术后晚期并发症无一例。常规组颌面部软重建愈合障碍高于梭形组(梭形组:5.26%,常规组:20.69%)。
    Fusiform设计的用于闭合腿部伤口和颌面部软缺损的皮肤桨是常规设计的皮肤桨的可行替代方案。梭形设计的皮肤桨减少了术后住院时间,腿部伤口愈合时间短,并发症少。
    UNASSIGNED: To investigate the feasibility of leg wound closure and reconstruction of maxillofacial soft defect by a fusiform-designed skin paddle in fibula free flap (FFF).
    UNASSIGNED: Fifty patients who underwent FFF for reconstruction of maxillofacial soft defect were divided into two groups. The fusiform group (20 patients) was treated using a fusiform-designed skin paddle in FFF (skin paddle width less than 2 cm), and leg wound was closed using primary suturing. Reconstruction of the maxillofacial soft defect or filling of dead space was achieved by folding the fusiform skin paddle. The conventional group (30 patients) was treated using the conventional-designed skin paddle (skin paddle width no less than 2.5 cm). The leg wound was closed using mattress suturing or skin graft, while reconstruction of the maxillofacial soft defect or filling of dead space by conventional way. The average postoperative length of hospital stay, healing time of leg wound, and post-surgical complications were recorded at least 6 months after the surgery.
    UNASSIGNED: Compared with traditional method, the fusiform-designed skin paddle reduced the average healing time of the leg wound (fusiform group: 11.05 days, conventional group: 14.77 days, P < 0.05). The average length-to-width ratio in fusiform group was significantly greater than that of in conventional group (fusiform group: 5.85, conventional group: 2.93, P < 0.05), and no difference was observed on the graft size of skin paddle between two groups (fusiform group: 23.13, conventional group: 27.13, P > 0.05). The post-surgical early complications of the leg wound in the conventional group were higher than that of in the fusiform group (fusiform group: 0%, conventional group: 6.67%), while the post-surgical late complication of the donor site between the two groups showed no case. Healing disorders of maxillofacial soft reconstruction in the conventional group were higher than that of in the fusiform group (fusiform group: 5.26%, conventional group: 20.69%).
    UNASSIGNED: Fusiform-designed skin paddle for closure of the leg wound and maxillofacial soft defect is a feasible alternative to the conventional- designed skin paddle. The fusiform- designed skin paddle resulted in the less postoperative length of hospital stay, shorter healing time of leg wound and less complication.
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  • 文章类型: Journal Article
    比较经胸超声心动图(TTE)和X射线引导的卵圆孔未闭(PFO)闭合的有效性。
    在这项回顾性研究中,回顾性分析2020年1月至2022年12月在永康市第一人民医院接受PFO封堵术的90例患者的临床资料.其中,43例患者行X线引导下PFO封堵术(X线组),47例患者行TTE引导下PFO封堵术(TTE组)。围手术期,治疗前后测定心功能相关指标,以及从右到左的分流状态,两组的并发症发生率。
    TTE组与X线组之间的手术时间或住院时间没有显着差异(p>0.05)。治疗后,两组患者的心功能指标均较治疗前升高(p<0.05),组间差异无统计学意义(p>0.05)。治疗后,两组患者的右向左分流较治疗前有所改善(p<0.05),组间无显著差异(p>0.05)。两组并发症比较差异无统计学意义(p>0.05)。
    TTE引导的PFO闭塞在PFO的治疗中与X射线引导的PFO闭塞一样有效。TTE手术在临床上有利于以良好的安全性减少辐射损伤。
    UNASSIGNED: To compare the effectiveness of transthoracic echocardiography (TTE) and X-ray guided closure of patent foramen ovale (PFO).
    UNASSIGNED: In this retrospective study, clinical data from 90 patients who underwent PFO occlusion surgery in the First People\'s Hospital of Yongkang from January 2020 to December 2022 were retrospectively reviewed. Among them, 43 patients underwent X-ray guided PFO occlusion surgery (X-ray group) while 47 patients underwent TTE guided PFO occlusion surgery (TTE group). Perioperative, cardiac function related indicators were measured before and after treatment, along with right-to-left shunting status, and incidence of complications in both groups.
    UNASSIGNED: There was no significant difference in the duration of surgery or hospitalization between the TTE group and the X-ray group (p>0.05). After treatment, the cardiac function indicators of both groups increased compared to before treatment (p<0.05), and there was no significant difference between the groups (p>0.05). After treatment, right-to-left shunting in the two groups improved compared to before treatment (p<0.05), with no significant difference between the groups (p>0.05). There was no significant difference in complications between the two groups (p>0.05).
    UNASSIGNED: TTE guided PFO occlusion is as effective as X-ray guided PFO occlusion in the treatment of PFO. TTE surgery is clinically beneficial for reducing radiation damage with a good safety profile.
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  • 文章类型: Journal Article
    背景:气管食管瘘(TEF)尤其是恶性TEF(mTEF)是一种罕见但危重的医学疾病,需要立即干预。这种危及生命的状况通常表现在重症患者中,这些患者依赖于长时间的机械通气,并且由于健康状况受损而不适合进行开胸手术。这些mTEF患者的管理仍然是一个重大挑战。本研究旨在评估使用心脏间隔封堵器闭合mTEF的安全性和有效性。
    方法:于2021-2023年在湖北省宜昌市中心人民医院呼吸科行房间隔缺损(ASD/VSD)房间隔封堵器封堵术治疗8例mTEF患者。该过程涉及通过瘘管经皮放置封堵器以实现闭合。
    结果:在所有患者中,心脏间隔封堵器的放置均成功且有效。研究表明,使用心脏间隔封堵器治疗mTEF患者可以缓解症状,提高生活质量,提高生存率,无明显并发症。此外,这项研究提供了关于手术适应症的全面细节,术前评估和诊断,封堵器的选择,遮挡的方法,和术后护理。
    结论:应用心脏间隔封堵器治疗mTEF是一种安全有效的姑息性治疗方法。这种方法对于具有与传统手术干预相关的并发症和死亡率高风险的患者可能特别有益。
    BACKGROUND: Tracheoesophageal fistula (TEF) especially malignant TEF (mTEF) is an uncommon yet critical medical condition necessitating immediate intervention. This life-threatening condition frequently manifests in critically ill patients who are dependent on prolonged mechanical ventilation and are unsuitable candidates for thoracotomy due to their compromised health status. The Management of these mTEF patients remain a significant challenge.This study aimed to evaluate the safety and efficacy of using a cardiac septal occluder for the closure of mTEF.
    METHODS: 8 patients with mTEF underwent closure surgery using atrial/ventricular septal defect (ASD/VSD) septal occluders at the Respiratory Department of HuBei Yichang Central People\'s Hospital from 2021 to 2023. The procedure involved percutaneous placement of the occluder through the fistula to achieve closure.
    RESULTS: The placement of the cardiac septal occluder was successfully achieved with ease and efficiency in all patients. The study demonstrated that the use of cardiac septal occluder therapy in patients with mTEF can alleviate symptoms, improve quality of life, and enhance survival rates, with no significant complications observed. Furthermore, the study provided comprehensive details on surgical indications, preoperative evaluation and diagnosis, selection of occluder, methods of occlusion, and postoperative care.
    CONCLUSIONS: The application of cardiac septal occluder in the treatment of mTEF is a safe and effective palliative treatment. This approach may be particularly beneficial for patients with a high risk of complications and mortality associated with traditional surgical interventions.
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  • 文章类型: Journal Article
    简介随着牙周病的发病率持续激增,牙周治疗的需求同时上升。进行牙周手术治疗以控制和消除疾病活动。传统上,丝线缝线被认为是导致生物膜积聚和组织创伤的术后皮瓣闭合的黄金标准。氰基丙烯酸酯是避免这些限制的备选方案。目的通过比较3-0编织丝线与氰基丙烯酸酯固定的牙周皮瓣手术后的愈合情况,评估临床疗效。方法选择10例中重度牙周炎患者的20个手术部位,经过1期治疗后随机分为两组:试验组(2-氰基丙烯酸异戊酯)和对照组(3-0丝编织线)。术后伤口愈合,使用言语评定量表(VRS)进行疼痛评估,和服用的止痛片在第三次进行了评估,第五,第七,第14天使用ANOVA检验和事后Bonferroni检验进行统计分析。结果组间比较,VRS和创面愈合指数在不同水平间隔期间差异无统计学意义。但与对照组相比,试验组术后消耗的镇痛药数量较少.结论本研究得出结论,2-氰基丙烯酸异戊酯可作为传统丝线的替代品,因为它可以减少术后疼痛和不适。
    Introduction As the incidence of periodontal diseases continues to surge, there is a concurrent elevation in the demand for periodontal treatment. Periodontal surgical therapy is done to control and eliminate disease activity. Conventionally, silk sutures have been considered the gold standard for post-operative flap closure that leads to biofilm accumulation and tissue trauma. Cyanoacrylates are alternate options to avoid the limitations. Objective The objective of the study was to assess clinical outcomes by comparing the healing after periodontal flap surgery when secured with 3-0 braided silk suture versus cyanoacrylate. Methodology Twenty surgical sites from 10 patients with moderate to severe periodontitis were selected and randomly divided into two groups after phase-1 therapy: the test group (isoamyl 2-cyanoacrylate) and the control group (3-0 silk braided suture). Post-operative wound healing, pain assessment using a verbal rating scale (VRS), and analgesic tablets taken were evaluated on the third, fifth, seventh, and 14th days. Statistical analysis was done using the ANOVA test with the post-hoc Bonferroni test. Results There was no statistically significant difference between the VRS and wound healing index at different levels of intervals during intergroup comparison, but the number of analgesics consumed post-operatively was less in the test group as compared to the control group. Conclusion The present study concluded that isoamyl 2-cyanoacrylate can be used as an alternative to conventional silk sutures as it decreases post-operative pain and discomfort.
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  • 文章类型: Journal Article
    使用背骨作为游离骨软骨骨移植物或血管化骨瓣已成为大型骨瓣的支柱,粉碎性中指骨掌侧唇骨折。迄今为止,很少有研究在评估供区发病率的半哈密特移植物或皮瓣,没有人讨论过这个供体部位的修复或重建模式。
    对14例半髋关节置换术(HHA)的回顾性分析,包括6个血管化移植物和8个非血管化移植物,两名外科医生进行了手术。使用了四种哈玛特缺损重建技术:没有正式重建,自体骨移植,凝胶泡沫,或合成骨替代物.背囊通过伸肌支持带移植或直接闭合来修复。手腕运动范围,疼痛评分,和射线照相对齐进行了评估。
    随访6个月时,所有患者都达到了完全,与未受伤的一侧相比,无痛的手腕运动,用视觉模拟量表疼痛评分为0。连续X光片显示腕骨对齐保持,没有不稳定或半脱位。没有证明基于hamate缺损重建方法或囊膜修复技术的差异。
    安全恢复无痛,HHA后可实现无限制的手腕功能,不管阻碍捐赠现场管理。适当的背侧囊修复对于防止不稳定至关重要。需要进一步的研究来比较技术,但在没有明确证据的情况下,选择可能会受到外科医生偏好的指导。
    UNASSIGNED: The use of the dorsal hamate as a free osteochondral bone graft or vascularized bone flap has become the mainstay for large, comminuted middle phalanx volar lip fractures. To date, few studies have been conducted in the assessment of donor site morbidity for the hemi-hamate graft or flap, and none have discussed modes of repair or reconstruction of this donor site.
    UNASSIGNED: A retrospective analysis of 14 hemi-hamate arthroplasty (HHA) procedures, including 6 vascularized and 8 non-vascularized grafts, from two surgeons was performed. Four hamate defect reconstruction techniques were utilized: no formal reconstruction, autologous bone grafting, gel foam, or synthetic bone substitute. The dorsal capsule was repaired with either extensor retinaculum grafting or by direct closure. Wrist range of motion, pain scores, and radiographic alignment were assessed.
    UNASSIGNED: At 6 months follow-up, all patients achieved full, pain-free wrist motion compared to the uninjured side, with visual analog scale pain scores of 0. Serial radiographs showed maintained carpal alignment without instability or subluxation. No differences based on the hamate defect reconstruction method or capsular repair technique was demonstrated.
    UNASSIGNED: Safe return to pain free, unrestricted wrist function is achievable after HHA, regardless of hamate donor site management. Adequate dorsal capsular repair appears critical to prevent instability. Further study is needed to compare techniques, but choice may be guided by surgeon preference in the absence of clear evidence.
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  • 文章类型: Journal Article
    鉴于关于商业失败的学术著作越来越多,在社会科学领域,令人惊讶的是,过去的研究在很大程度上忽视了极端的环境冲击和“黑天鹅”事件,比如冠状病毒(COVID-19)大流行和其他全球危机造成的事件,可能会导致业务失败。从当前关于商业失败和COVID-19正在展开的事件的文献中汲取见解,我们强调了新的外生冲击带来的悖论(即,超越过去经验的冲击)及其对中小企业的影响。大流行加速了国家和市场之间关系的重新配置,扩大有政治联系的人和没有政治联系的人之间的差距,它可能会给一些参与者带来新的合法性挑战,即使其他人似乎不太关心这些问题,而经验知识资源可能既是优势,也是负担。
    In light of growing scholarly works on business failure, across the social science domains, it is surprising that past studies have largely overlooked how extreme environmental shocks and \'black swan\' events such as those caused by the coronavirus (COVID-19) pandemic and other global crises, can precipitate business failures. Drawing insights from the current literature on business failure and the unfolding event of COVID-19, we highlight the paradoxes posed by novel exogenous shocks (that is, shocks that transcend past experiences) and the implications for SMEs. The pandemic has accelerated the reconfiguration of the relationship between states and markets, increasing the divide between those with political connections and those without, and it may pose new legitimacy challenges for some players even as others seem less concerned by such matters, whilst experiential knowledge resources may be both an advantage and a burden.
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  • 文章类型: Case Reports
    我们报告了在左前降支冠状动脉次全闭塞血运重建过程中,由于扫雪现象而自发闭合1级冠状动脉穿孔的极为罕见的情况。冠状动脉穿孔通常是心导管实验室冠状动脉介入治疗期间的噩梦。虽然大的冠状动脉穿孔需要展开覆膜支架,小穿孔需要肝素逆转,长时间的气球充气,部署小线圈,或凝胶泡沫闭合。有小穿孔的冠状动脉节段用药物洗脱支架(DES)进行支架,这可能导致脂肪斑块向穿孔转移,随后密封冠状动脉穿孔。
    We report an extremely rare case of spontaneous closure of grade 1 coronary perforation by the snowplow phenomenon during the revascularization of a subtotal occlusion in the left anterior descending coronary artery. Coronary artery perforation is usually a nightmare during coronary intervention in the cardiac catheterization laboratory. While large coronary perforation requires the deployment of a covered stent, small perforations require heparin reversal, prolonged balloon inflation, deployment of small coils, or gel foam closure. The coronary segment with a small perforation was stented with a drug-eluting stent (DES), which might have resulted in the shifting of the fatty plaque toward the perforation and subsequently sealing the coronary perforation.
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  • 文章类型: Journal Article
    皮层视觉区域,V4已被认为是对有助于对象的中级表示的轮廓进行编码。对自然轮廓固有的复杂轮廓特征的神经响应有望阐明表示的本质。为了接近自然轮廓的皮质编码,我们研究了猴子(Macacafuscata)V4神经元中多个轮廓特征的同时编码及其种群水平表示。大量的神经元显示出两个或更多的特征,如曲率和闭合,这表明大量的V4神经元同时编码多个轮廓特征。大部分神经元对围绕经典感受野中心的急剧弯曲的轮廓做出了强烈反应,这表明V4神经元倾向于编码物体轮廓的突出特征。对神经反应和每个轮廓特征之间的互信息(MI)的分析表明,对于每种类型的MI,大多数神经元表现出相似的幅度,表明许多神经元显示的反应取决于多个轮廓特征。接下来,我们使用多维缩放分析检查了人口水平的表示。与轮廓刺激相比,神经对多种轮廓特征的偏好以及对自然刺激的偏好随着主轴和次轴的增加而增加。分别,表明多种轮廓特征和表面纹理在种群响应中的贡献。我们的分析表明,V4神经元同时在自然图像中编码多个轮廓特征,并表示群体中的轮廓和表面属性。重要性陈述自然物体的轮廓通常很复杂,但视觉系统会提取它们的特征并有效地表示它们的形状。中级视觉皮层的神经元,V4,对自然轮廓的表示起着至关重要的作用。分析电生理数据,我们发现V4神经元同时编码多个轮廓特征,如曲率,关闭,和方向,并代表突出的轮廓,如角落和凸起。例如,许多神经元对封闭物体范围的急性曲率做出反应。互信息和种群分析表明,许多神经元的反应取决于多个轮廓特征,并代表种群中的轮廓和表面。一群V4神经元似乎编码了复杂但突出的轮廓,以表示自然物体。
    The cortical visual area, V4, has been considered to code contours that contribute to the intermediate-level representation of objects. The neural responses to the complex contour features intrinsic to natural contours are expected to clarify the essence of the representation. To approach the cortical coding of natural contours, we investigated the simultaneous coding of multiple contour features in monkey (Macaca fuscata) V4 neurons and their population-level representation. A substantial number of neurons showed significant tuning for two or more features such as curvature and closure, indicating that a substantial number of V4 neurons simultaneously code multiple contour features. A large portion of the neurons responded vigorously to acutely curved contours that surrounded the center of classical receptive field, suggesting that V4 neurons tend to code prominent features of object contours. The analysis of mutual information (MI) between the neural responses and each contour feature showed that most neurons exhibited similar magnitudes for each type of MI, indicating that many neurons showing the responses depended on multiple contour features. We next examined the population-level representation by using multidimensional scaling analysis. The neural preferences to the multiple contour features and that to natural stimuli compared with silhouette stimuli increased along with the primary and secondary axes, respectively, indicating the contribution of the multiple contour features and surface textures in the population responses. Our analyses suggested that V4 neurons simultaneously code multiple contour features in natural images and represent contour and surface properties in population.
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  • 文章类型: Journal Article
    背景和目的:切口疝的预防已成为外科医生在腹壁手术的重要概念。已经提出了几种技术来帮助减少切口疝的形成,腹壁的缝线闭合是基石之一。据报道可以降低切口疝发生率的技术细节包括实现4:1的缝合线与伤口长度之比以及使用小咬伤技术。尽管有证据支持许多这些技术,但执业外科医生之间的实践模式似乎存在差距。在外科住院医师中引入和推广这些原则可能有助于缩小这一差距。本文回顾了我们在机构进行腹壁闭合手术培训的经验。材料和方法:2010年至今,我们对与腹壁闭合相关的计划和项目进行了回顾。项目类型,干预,对教育的影响进行了评价和总结。结果:确定了七个与手术训练和腹壁闭合有关的项目。三个项目使用腹壁模拟模型进行了技能培训,并与缝合技术相关。两个项目是临床研究,重点是缝合线与伤口长度之比,并在住院医师培训计划中改善该变量的结果。两个项目涉及与腹壁闭合和教育有关的模型。结论:在手术住院医师计划中实施教育计划可以改善腹壁闭合的技术和知识,并有助于研究工作。
    Background and Aims: Incisional hernia prevention has become an important concept for surgeons operating on the abdominal wall. Several techniques have been proposed to help decrease incisional hernia formation with suture closure of the abdominal wall being one of the cornerstones. Technical details that have been reported to decrease incisional hernia rates include achieving a 4:1 Suture to Wound length ratio and the use of a small bites technique. Despite evidence to support many of these techniques there appears to be a gap in practice patterns amongst practicing surgeons. Introducing and promoting these principles in surgical residency may help to close this gap. This paper reviews our experience with surgical training for abdominal wall closures at our institution. Materials and Methods: Programs and projects related to abdominal wall closure were reviewed from our institution from 2010-Present. Type of project, intervention, and impact on education was evaluated and summarized. Results: Seven projects were identified relating to surgical training and abdominal wall closure. Three projects dealt with skills training using an abdominal wall simulation model and related to suturing techniques. Two projects were clinical studies focused on suture to wound length ratios and improving outcomes with this variable in a residency training program. Two projects dealt with models relating to abdominal wall closure and education. Conclusion: Implementation of educational programs in surgical residency programs can lead to improvements in technique and knowledge around abdominal wall closure and help in research endeavors.
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