■自闭症谱系障碍(ASD)是一种复杂的神经发育状况,其特征是症状和挑战广泛。虽然ASD主要与非典型的社交和交际行为有关,越来越多的研究指出大脑各个区域的参与,包括小脑.这篇综述文章旨在全面概述小脑小叶在ASD中的作用。强调最近的发现和潜在的治疗意义。
■使用PubMed中已发布的文章,Scopus,和谷歌学者,我们提取了相关数据来完成这项审查工作。我们已经搜索了包括解剖学见解在内的术语,神经影像学,神经生物学,和自闭症谱系障碍。
■神经生物学研究强调了小脑和与ASD相关的其他大脑区域之间的复杂关系,显示神经递质系统和小脑电路异常。在ASD的病理生理学中小脑的相关性已经被进一步强调的解剖研究,已经揭示了小脑异常的证据,包括音量的变化,形态学,和连通性。
■对ASD中小脑功能的深入了解可能会导致对该病症的潜在机制的新理解,并更容易创建更有针对性的干预措施和治疗方法,以治疗ASD患者的小脑功能障碍。
UNASSIGNED: Autism spectrum disorder (ASD) is a complex neurodevelopmental condition characterized by a wide range of symptoms and challenges. While ASD is primarily associated with atypical social and communicative behaviors, increasing research has pointed towards the involvement of various brain regions, including the
cerebellum. This review article aims to provide a comprehensive overview of the role of cerebellar lobules in ASD, highlighting recent findings and potential therapeutic implications.
UNASSIGNED: Using published articles found in PubMed, Scopus, and Google Scholar, we extracted pertinent data to complete this review work. We have searched for terms including anatomical insights, neuroimaging, neurobiological, and autism spectrum disorder.
UNASSIGNED: The intricate relationship between the
cerebellum and other brain regions linked to ASD has been highlighted by neurobiological research, which has shown abnormalities in neurotransmitter systems and cerebellar circuitry. The relevance of the
cerebellum in the pathophysiology of ASD has been further highlighted by anatomical studies that have revealed evidence of cerebellar abnormalities, including changes in volume, morphology, and connectivity.
UNASSIGNED: Thorough knowledge of the
cerebellum\'s function in ASD may lead to new understandings of the underlying mechanisms of the condition and make it easier to create interventions and treatments that are more specifically targeted at treating cerebellar dysfunction in ASD patients.