背景:双相情感障碍(BD)是一种严重的精神疾病。BD常与边缘性人格障碍并存,使情况变得更加复杂。
目的:探讨BD患者与BD合并边缘性人格障碍患者认知功能损害的差异。
方法:将80例BD合并边缘性人格障碍患者和80例单纯BD患者作为A组和B组,分别,80名健康志愿者作为对照.使用中文版的可重复电池评估每个组的认知功能,以评估神经心理学状态(RBANS),Stroop颜色词测试,和韦氏情报量表修订(WAIS-RC)。
结果:RBANS的指数,Stroop颜色词测试,A、B组WAIS-RC明显低于对照组(P<0.05)。A组单个字符的Stroop颜色词测试时间明显更长,单色,双字符,和双色,即时记忆得分较低,视觉广度,RBANS的言语功能维度和总分,以及较低的言语智商,性能IQ,WAIS-RC总体智商与B组比较(P<0.05)。与B组相比,A组表现出明显更长的单字符时间,单色时间,双字符时间,Stroop颜色词检验中的双色时间(P<0.05)。
结论:BD合并边缘性人格障碍患者的认知功能低于BD患者。
BACKGROUND: Bipolar disorder (BD) is a severe mental illness. BD often coexists with borderline personality disorders, making the condition more complex.
OBJECTIVE: To explore the differences in cognitive impairment between patients with BD and those with BD comorbid with borderline personality disorder.
METHODS: Eighty patients with BD and comorbid borderline personality disorder and 80 patients with BD alone were included in groups A and B, respectively, and 80 healthy volunteers were included as controls. Cognitive function in each group was evaluated using the Chinese version of the repeatable battery for the assessment of neuropsychological status (RBANS), the Stroop color-word test, and the Wechsler intelligence scale-revised (WAIS-RC).
RESULTS: The indices of the RBANS, Stroop color-word test, and WAIS-RC in groups A and B were significantly lower than those of the control group (P < 0.05). Group A had significantly longer Stroop color-word test times for single-character, single-color, double-character, and double-color, lower scores of immediate memory, visual breadth, verbal function dimensions and total score of the RBANS, as well as lower scores of verbal IQ, performance IQ, and overall IQ of the WAIS-RC compared with group B (P < 0.05). Compared to group B, group A exhibited significantly longer single-character time, single-color time, double-character time, and double-color time in the Stroop color-word test (P < 0.05).
CONCLUSIONS: The cognitive function of patients with BD complicated with borderline personality disorder is lower than that of patients with BD.