Biliary peritonitis

胆汁性腹膜炎
  • 文章类型: Case Reports
    自发性胆管穿孔引起的胆汁性腹水是一种罕见的病例,通常在6-36个月的儿科年龄组中看到。我们正在介绍一个14个月大的婴儿腹胀伴腹痛的病例,呕吐,发烧,和没有大便的历史。经检查,腹部紧张而柔软。关于放射学调查,腹腔中存在大量游离液,并伴有肠梗阻和脾胃部分倒置。经直肠刺激后肠梗阻缓解,之后口服喂养耐受性良好。诊断性穿刺发现胆汁液,确认诊断。患者进一步接受广谱抗生素和游离液体引流治疗。治疗范围从保守治疗到Roux-en-Y吻合术。非手术诊断是罕见的,如果早期发现,有助于改善患者的预后。此病例报告强调了危重患者早期诊断和非手术治疗方式的重要性。
    Biliary ascites due to spontaneous biliary duct perforation is a rare case presentation usually seen in the paediatric age group of 6-36 months. We are presenting the case of a 14-month-old baby with abdominal distention associated with abdominal pain, vomiting, fever, and a history of no passage of stools. Upon examination, the abdomen was tense and tender. On radiological investigations, gross free fluid was present in the abdominal cavity along with bowel obstruction and partial situs inversus of the spleen and stomach. The bowel obstruction was relieved by rectal stimulation, after which oral feeds were well tolerated. Bilious fluid was found on diagnostic paracentesis, confirming the diagnosis. The patient was managed further by broad-spectrum antibiotics and drainage of the free fluid. The management ranges from conservative treatment to Roux-en-Y anastomosis. A non-surgical diagnosis is uncommonly seen and helps improve the patient\'s prognosis if detected early. This case report highlights the importance of early diagnosis and non-surgical treatment modality in critical patients.
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  • 文章类型: Journal Article
    这项研究的目的是对从胆囊穿孔患者收集的数据进行回顾性分析,以进行诊断。管理和结果。
    对40例胆囊穿孔患者的住院记录进行了回顾性分析,这些患者在术前和术中诊断为胆囊穿孔病例,为期10年,并在我们的三级医疗保健中心的外科部门进行管理。除创伤病例和儿科年龄组患者外,患者不分性别。
    在40名患者中,女性26人,男性14人。根据安德森对Neimeier分类的修改,13例(32.5%)为1型,23例(57.5%)为2型,4例(10%)患者为3型穿孔,没有患者为4型穿孔。23例(57.5%)患者被发现有眼底穿孔,其次是身体11例(27.5%),三个(7.5%)在哈特曼的袋中,而三个患者(7.5%),有多个穿孔。所有1型Neimer分级的患者均临床诊断为胆源性腹膜炎,而大多数2型Neimer分类病例在术前通过CECT腹部12/23患者(52%)和超声腹部10/23(43.47%)诊断。所有患者都接受了手术,有三个死亡。
    在我们的研究中,胆囊穿孔患者以女性为主。在患者中,52.5%为糖尿病患者,平均年龄为55.9岁。CECT腹部是诊断2型胆囊穿孔最有用的方式。为了更好地治疗这些病例,必须进行及时的手术干预。
    UNASSIGNED: The aim of this study was to perform retrospective analysis of data collected from patients of gallbladder perforations for diagnosis, management and outcome.
    UNASSIGNED: A retrospective analysis of data was carried out for 40 patients of gallbladder perforations from the hospital record of patients who were diagnosed preoperatively and intraoperatively as a case of gallbladder perforation over a period of 10 years and were managed in our surgery unit of a tertiary health care centre. Patients were included irrespective of sex except cases of trauma and patients of the paediatric age group.
    UNASSIGNED: Among 40 patients, 26 were females and 14 were males. As per Anderson modification of Neimeier classification, 13 (32.5%) had type 1, 23 (57.5%) had type 2, and four (10%) patients had type 3 perforations and none of the patients had type 4 perforation. Twenty-three patients (57.5%) were found to have fundal perforation, followed by body in 11 patients (27.5%), three (7.5%) in Hartman\'s pouch while in three patients (7.5%), there were multiple perforations. All patients of type 1 Neimer classification were diagnosed clinically as cases of biliary peritonitis, whereas most cases of type 2 Neimer classification were diagnosed preoperatively by CECT abdomen 12/23 patients (52%) and ultrasound abdomen 10/23 (43.47%). All patients underwent surgery, and there were three mortalities.
    UNASSIGNED: In our study, there was female predominance in patients having gallbladder perforation. Of the patients, 52.5% were diabetic and mean age was 55.9 years. CECT abdomen was the most useful modality for diagnosis of type 2 gallbladder perforations. Timely surgical intervention is mandatory for a better outcome of these cases.
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  • 文章类型: Case Reports
    胆汁性腹膜炎是代表具有高死亡风险的医疗紧急情况的病理状况。这种情况在胆道破裂后的人类和兽医学中都有报道,肝外胆道梗阻,胆囊破裂,创伤,或者十二指肠穿孔.在这份报告中,描述了首例Bobtail纯种犬因胃穿孔引起的胆汁性腹膜炎,这可能是由非甾体抗炎药(NSAIDs)引起的。选择性脾切除和去势后,这只狗因食欲不振被转诊到我们医院接受医疗管理,精神抑郁,和多次胃部呕吐并有血迹.临床诊断测试显示存在胆汁性腹膜炎。由于临床状况恶化,病人接受了安乐死。宏观检查显示游离的褐色腹腔积液和胃幽门区穿孔性溃疡。
    Biliary peritonitis is a pathological condition representing a medical emergency with a high risk of mortality. This condition is reported in both human and veterinary medicine following biliary tract rupture, extrahepatic biliary obstructions, gallbladder rupture, trauma, or duodenal perforation. In this report, the first-ever case of biliary peritonitis due to gastric perforation in a Bobtail purebred dog is described, which was probably induced by the administration of nonsteroidal anti-inflammatory drugs (NSAIDs). After an elective splenectomy and castration, the dog was referred to our hospital for medical management for inappetence, mental depression, and multiple episodes of gastric vomits with traces of blood. Clinical diagnostic tests showed the presence of biliary peritonitis. Due to worsening clinical conditions, the patient was subjected to euthanasia. Macroscopic examination showed a free brownish abdominal effusion and the presence of perforating ulcer of the stomach pylorus region.
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  • 文章类型: Case Reports
    胆总管自发性穿孔(SPCBD)是一种特殊的疾病,尤其是成年人。一旦排除创伤和胆总管囊肿,原因通常是特发性的。早期诊断往往是困难的,因为它经常误导的外观。
    未经授权:作者报告了一名54岁男子的病例,一个已知的2型糖尿病病例,他因急性腹痛出现在我们的急诊科,这种疼痛已经持续了2天。
    未经授权:在体检时,病人发烧高达38.5摄氏度,腹部扩张,通常很紧。腹部计算机断层扫描证实存在游离液体。此外,与解决的胆囊扩张相比,胆囊壁的厚度增加了。因为探索未能证明腹水的原因,作者进行了诊断性穿刺,露出深黄绿色的腹水,这意味着胆漏。初步复苏后,进行了紧急剖腹探查术.作者发现继发于SPCBD的胆汁性腹膜炎。腹腔灌洗后,穿孔是在T形管上修复的。术后病程顺利。组织学发现与溃疡性非结石性胆囊炎一致。经过3个月的随访,患者无病。
    未经评估:SPCBD在成人中并不常见,这在文献中很少报道。本病的发病机制尚不明确,可能与单因素或多因素有关。通常,这种疾病是在死后诊断出来的。早期诊断和最佳手术治疗具有挑战性。
    UNASSIGNED:本病例强调了SPCBD的术前诊断困难。应在尽可能短的时间内进行紧急手术治疗,以降低高死亡率。
    Spontaneous perforation of the common bile duct (SPCBD) is an exceptional disease, especially in adults. The cause is often idiopathic once trauma and choledochal cyst are excluded. Early diagnosis is often difficult because of its often-misleading appearance.
    UNASSIGNED: The authors report the case of a 54-year-old man, a known case of type 2 diabetes mellitus, who presented to our emergency department for acute abdominal pain that had evolved for 2 days.
    UNASSIGNED: On physical examination, the patient had a fever of up to 38.5°C, and the abdomen was distended and generally tight. The abdominal computerized tomography scan confirms the presence of free fluid. In addition, the thickness of the gallbladder wall had increased in contrast with a resolved gallbladder distention. Because exploration failed to demonstrate the cause of ascites, the authors performed a diagnostic paracentesis, which revealing ascites with a dark yellow-green color, which implied bile leakage.After initial resuscitation, an emergent exploratory laparotomy was performed. The authors found biliary peritonitis secondary to SPCBD. After peritoneal lavage, the perforation was repaired over a T-tube. The postoperative course was uneventful. Histological findings were consistent with ulcerous acalculous cholecystitis. The patient was disease-free after a 3-month follow-up.
    UNASSIGNED: SPCBD is an uncommon condition in adults, and it is rarely reported in the literature. The pathogenesis of this disease is not clear and may be related to single or multiple factors. Usually, this disease is diagnosed in the postmortem. Early diagnosis and optimal surgical treatment are challenging.
    UNASSIGNED: This present case highlighted the preoperative diagnostic difficulties of the SPCBD. Emergent surgical management should be instituted in the shortest time possible to reduce the high mortality.
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  • 文章类型: Case Reports
    背景:乳糜胸是一种罕见的疾病,其中乳糜渗入胸膜腔,胆源性腹膜炎是临床上少见的胸导管栓塞并发症。
    方法:我们描述了一名50岁女性的病例,该女性表现为乳糜胸,并使用线圈和组织泪胶和碘油的混合物进行了胸导管栓塞。干预后患者出现上腹痛和发热。她被诊断为胆汁性腹膜炎,并在河内医科大学医院接受胆囊切除术治疗。
    结论:尽管胸导管栓塞术被认为是一种安全且微创的手术,这并非没有风险。胸导管栓塞后,应利用影像学数据和实验室检查结果来探索严重或持续性腹痛,以尽快确定问题。
    BACKGROUND: Chylothorax is an uncommon condition in which chyle leaks into the pleural cavity, and biliary peritonitis is a rare complication of thoracic duct embolization in clinical practice.
    METHODS: We describe the case of a 50-year-old woman who presented with chylothorax and underwent thoracic duct embolization using a coil and a mixture of histoacryl glue and lipiodol. The patient developed upper abdominal pain and fever after the intervention. She was diagnosed with biliary peritonitis and treated with cholecystectomy at Hanoi Medical University Hospital.
    CONCLUSIONS: Although thoracic duct embolization is considered a safe and minimally invasive procedure, it is not without risk. Following thoracic duct embolization, severe or persistent abdominal pain should be explored utilizing imaging data and laboratory results to determine problems as soon as possible.
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  • 文章类型: Case Reports
    急性胰腺炎可引起多种局部并发症,有时很不寻常。在本报告中,在急性胰腺炎的背景下,我们提出了一个相当不寻常的胆汁性腹膜炎的原因。病例介绍一名41岁的胆源性急性胰腺炎和合并胆总管结石的女性患者在进行保守治疗后,由于败血症和腹膜刺激的迹象,需要紧急剖腹手术。在剖腹手术中,诊断为胆源性腹膜炎。令人惊讶的是,残余的胆结石阻塞壶腹水平的胆总管导致胆汁回流,通过公共频道,进入主胰管,随后进入部分破裂的急性胰腺坏死集合。结论应对意外情况是应对急性胰腺炎患者的外科团队不断面临的挑战。尽管在急性胰腺炎的过程中推迟了手术干预,尽可能多,是理想的策略,这并不总是可能的。根据患者的临床状况决定治疗策略是最合适的方法。
    Introduction  Acute pancreatitis can cause a wide variety of local complications, sometimes pretty unusual. In the present report, we present a rather unusual cause of biliary peritonitis on the background of acute pancreatitis. Case Presentation  A 41-year-old female patient with biliary acute pancreatitis and concomitant choledocholithiasis required an urgent laparotomy due to signs of sepsis and peritoneal irritation after a trial of conservative management. During laparotomy, the diagnosis of biliary peritonitis was established. Surprisingly, a residual gallstone obstructing the common bile duct at the level of the ampulla was causing bile to reflux, through the common channel, into the main pancreatic duct and subsequently into a partially ruptured acute pancreatic necrotic collection. Conclusion  Dealing with the unexpected is a constant challenge for the surgical team dealing with acute pancreatitis patients. Although deferring surgical intervention during the course of acute pancreatitis, as much as possible, is the ideal strategy, this is not always possible. Deciding the treatment strategy based on the patients\' clinical condition represents the most appropriate approach.
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  • 文章类型: Case Reports
    UASSIGNED:T管的目的是在胆总管中诱发其周围的炎症,形成用于引流胆汁的纤维道。去除T形管后,胆汁渗入腹膜是严重的并发症。在持续疼痛且具有保护性和刚性的情况下,可以对腹膜进行临时诊断。成像技术可用于胆漏的鉴别。在大多数情况下,患者恢复与保守或手术管理。
    UNASSIGNED:我们向您介绍了一名65岁营养不良的女性,在T型管摘除后立即出现胆腹膜特征,并计划在外科重症监护病房进行保守治疗和持续监测。尽管经过适当的治疗,患者仍恶化,并进入感染性休克,导致她死亡。
    未经证实:胆性腹膜炎并不少见,但它是T管拔除后危及生命的并发症。不良的营养状况也可能导致瘘管形成的延迟,并且在去除T形管期间存在胆漏的相对风险。乳胶T型管的使用在成熟道形成中更有效,胆漏的发生率较低。Seldinger\的方法,其中包括使用金属丝引导T形管的移除,显示胆漏显著减少。
    未经证实:在胆汁感染的情况下,胆汁性腹膜炎的死亡率显著上升。拔除T管后的不良反应为4.3%,约3%严重到足以入院。
    UNASSIGNED: The purpose of T-tubes is to induce inflammation around it in the common bile duct, forming a fibrous tract for drainage of bile. The leakage of bile into the peritoneum is a drastic complication following T-tube removal. A provisional diagnosis of choleperitoneum is established in the presence of persistent pain with guarding and rigidity. Imaging techniques can be used for the identification of biliary leakage. With most cases, patients recover with either conservative or surgical management.
    UNASSIGNED: We present you a 65 years old malnourished female with features of choleperitoneum immediately following T-tube removal and was planned for conservative management with constant monitoring in surgical intensive care unit. The patient deteriorated despite adequate treatment and went into septic shock which resulted into her demise.
    UNASSIGNED: Biliary peritonitis is not very uncommon but a life-threatening complication of T-tube removal. Poor nutritional status may also lead to delay in fistulous tract formation and there is a relative risk of biliary leakage during removal of T-tube. The use of a latex T-tube is more effective in mature tract formation and has less incidence of bile leakage. Seldinger\'s method, which involves using a wire to guide the removal of the T-tube, shows a significant reduction of biliary leakage.
    UNASSIGNED: The mortality in biliary peritonitis significantly rises in cases of infected bile. The adverse reaction following the removal of T-tube was 4.3% and about 3% were severe enough to be admitted to the hospital.
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  • 文章类型: Journal Article
    胆囊穿孔在手术患者中很少见。罕见的发生是由于难以诊断胆囊穿孔。本研究的目的是确定可以降低与这种潜在威胁生命的疾病相关的发病率和死亡率的最佳管理策略。
    这是一项来自医院健康记录的回顾性研究,其中40例连续胆囊破裂患者的经历,无论是自发的还是继发于良性疾病和恶性肿瘤,从2017年2月到2021年1月,在一家三级护理医院超过48个月被发现。病因,临床表现,并对所给予的治疗进行了分析。
    在40名患者中,23为女性,大多数患者年龄超过45岁。12例患者仅对静脉抗生素和镇痛药有反应,而5例患者由于临床状况未改善而需要超声引导的猪尾导管引流。期待管理失败导致7例患者延迟剖腹手术,而4例因全身性腹膜炎而需要紧急剖腹手术。在同一入院的诊断性腹腔镜检查后,对12例胆囊肠瘘患者进行了选择性胆囊切除术。38例患者病情稳定,在30天的随访中表现良好。
    与其他疾病相比,胆囊穿孔更常见于急性结石性胆囊炎。当急性结石性胆囊炎的治疗延迟超过6-8周时,更为明显。临床表现的范围从轻度疼痛和呕吐到全身性腹膜炎不等。患者通常需要逐步方法来控制正在进行的败血症以改善结果。
    UNASSIGNED: Gallbladder perforation is an infrequent entity seen among surgical patients. Rare occurrence owes to difficulty in diagnosing gallbladder perforations. The aim of the present study was to determine the optimal management strategy that may decrease the morbidity and mortality associated with this potentially life-threatening condition.
    UNASSIGNED: This was a retrospective study from hospital health records wherein the experience of 40 consecutive patients with gallbladder rupture, either spontaneous or secondary to both benign conditions and malignancy, was noted at a tertiary care hospital over 48 months from February 2017 till January 2021. The etiology, clinical presentation, and treatment given were analysed.
    UNASSIGNED: Out of 40 patients included, 23 were females and the majority of patients were more than 45 years of age. Twelve patients responded to intravenous antibiotics and analgesics alone while five required an ultrasound-guided pigtail catheter drainage due to non-improving clinical condition. The failure of expectant management led to a delayed laparotomy in seven patients while four patients required emergency laparotomy because of generalized peritonitis. An elective cholecystectomy was offered to 12 patients with cholecystoenteric fistulae after diagnostic laparoscopy in the same admission. Thirty-eight patients were discharged in stable condition and doing well at 30-day follow-up.
    UNASSIGNED: Gallbladder perforation is seen more commonly in acute calculous cholecystitis compared to other conditions. It is more evident when the treatment of acute calculous cholecystitis is delayed by more than 6-8 weeks. The spectrum of clinical presentation varies from mild pain and vomiting to generalized peritonitis. The patient often requires a step-up approach to control the ongoing sepsis for an improved outcome.
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  • 文章类型: Case Reports
    教学要点:自发性穿孔伴胆汁性腹膜炎是胆管囊肿的罕见并发症,在出现急腹症的患者中应考虑。腹水,和扩张的胆道树成像。
    Teaching point: Spontaneous perforation with biliary peritonitis is a rare complication of bile duct cysts which should be considered in a patient presenting with acute abdomen, ascites, and dilated biliary tree on imaging.
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  • 文章类型: Case Reports
    背景:常染色体显性遗传性多囊肾病(ADPKD)是最常见的遗传性肾脏疾病,多囊性肝病是其主要的肾外表现,然而,由于肝囊肿破裂引起的胆汁性腹膜炎极为罕见。
    方法:患者是一名71岁的日本女性,3年前被诊断为ADPKD,1个月前突然出现右腹痛。由于腹部计算机断层扫描(CT)显示右叶肝囊肿破裂,她被送进了医院。通过保守治疗,她的症状有所改善,1周后出院。虽然她有一段时间没有症状,出院后1个月,她注意到腹胀和全身不适。由于腹部CT显示大量腹水,她又被送进了医院。体格检查显示腹胀无压痛。她的血清肌酐,碱性磷酸酶,γ-谷氨酰转肽酶,总胆红素,CA19-9升高。腹腔穿刺术显示琥珀色透明腹水,胆红素和CA19-9浓度高。由于肝囊肿破裂,她被诊断为胆汁性腹膜炎。血液透析治疗始于腹水引流。腹水的流出没有减少的趋势,滴注胆管造影(DIC)-CT显示破裂的囊肿与肝内胆管之间存在连通。在第31天,她被转移到大学医院,并进行了腹部手术。切除肝右叶破裂囊肿的坏死屋顶后,胆漏口缝合。进行了胆囊切除术,胆道造影显示胆总管无结石。术后1个月腹部CT显示无腹水复发,第49天出院。出院后立即停止血液透析治疗,因为尿量增加,肌酐水平降低。此后没有腹水复发。
    结论:虽然罕见,在ADPKD患者中,由于囊肿和肝内胆管之间的沟通,胆汁性腹膜炎可能与肝囊肿破裂有关,当怀疑胆道囊肿破裂时,应建议使用DIC-CT。
    BACKGROUND: Autosomal dominant polycystic kidney disease (ADPKD) is the most frequent genetic kidney disease and polycystic liver disease is its major extrarenal manifestation, however biliary peritonitis due to a liver cyst rupture is extremely rare.
    METHODS: The patient was a 71-year-old Japanese woman who was diagnosed with ADPKD 3 years previously and developed right abdominal pain suddenly 1 month previously. As abdominal computed tomography (CT) showed a ruptured liver cyst in the right lobe, she was admitted to our hospital. Her symptoms improved with conservative management and she was discharged from the hospital after 1 week. Although she was asymptomatic for a while, she noticed abdominal distension and general malaise at 1 month after hospital discharge. Since abdominal CT showed massive ascites, she was admitted to our hospital again. A physical examination revealed abdominal distention without tenderness. Her serum creatinine, alkaline phosphatase, γ-glutamyl transpeptidase, total bilirubin, and CA19-9 were elevated. Abdominal paracentesis revealed amber transparent ascites and the bilirubin and CA19-9 concentrations were high. She was diagnosed with biliary peritonitis due to a ruptured liver cyst. Hemodialysis treatment was initiated with drainage of the ascites. The outflow of the ascites was no tendency to decrease and drip infusion cholangiography (DIC)-CT revealed a communication between the ruptured cyst and an intrahepatic bile duct. On day 31, she was transferred to a university hospital and abdominal surgery was performed. After removing the necrotic roof of the ruptured cyst on the right liver lobe, the orifice of the bile leakage was sutured. Cholecystectomy was performed and cholangiography showed no stones in the common bile duct. Abdominal CT one month after the operation showed no recurrence of ascites and she was discharged on day 49. Hemodialysis treatment was discontinued immediately after discharge because urine volume increased and her creatinine level decreased. There has been no recurrence of ascites since then.
    CONCLUSIONS: While rare, biliary peritonitis can occur in association with the rupture of a liver cyst in ADPKD patients due to communication between the cyst and the intrahepatic bile duct, and DIC-CT should be recommended when biliary cyst rupture is suspected.
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