■这项调查旨在阐明饮食中维生素E摄入量之间的相关性,B6,烟酸和白内障的发病率,利用全面的NHANES2005-2008数据集来确认这些营养素对白内障形成的预防作用。
■使用NHANES2005-2008周期的数据,这项分析集中于7,247名受试者,根据不完整的饮食或白内障数据进行排除.白内障的鉴定是通过参与者自我报告的眼科手术史确定的。使用自动多次通过方法测量营养摄入量,数据采用logistic和分位数回归分析,探讨维生素摄入量与白内障患病率之间的关系.
■我们的分析确定了维生素E,B6,和烟酸与白内障发展的风险有关。具体来说,前四分位数中维生素B6(OR=0.85,95%CI=0.76~0.96,p=0.0073)和烟酸(OR=0.98,95%CI=0.97~1.00,p=0.0067)的摄入量较高与白内障发生的可能性降低显著相关.维生素E摄入显示不同摄入水平的白内障风险持续降低(OR=0.96,95%CI=0.94-0.99,p=0.0087),证明了非线性逆相关。
■结果表明,维生素B6和烟酸的摄入量增加,与常规维生素E摄入相结合,可能有延缓或预防白内障发生的潜力。这些结果为白内障预防和管理提供了一种新的营养策略。主张有重点的营养补充可能有助于保持眼睛健康和降低白内障的风险。建议进一步研究以验证这些发现并建立最佳剂量以获得最大益处。
UNASSIGNED: This investigation aims to elucidate the correlations between dietary intakes of vitamin E, B6, and niacin and the incidence of cataracts, utilizing the comprehensive NHANES 2005-2008 dataset to affirm the prophylactic roles of these nutrients against cataract formation.
UNASSIGNED: Using data from the NHANES 2005-2008 cycles, this analysis concentrated on 7,247 subjects after exclusion based on incomplete dietary or cataract data. The identification of cataracts was determined through participants\' self-reported ophthalmic surgical history. Nutritional intake was gauged using the automated multiple pass method, and the data were analyzed using logistic and quantile regression analyses to investigate the relationship between vitamin consumption and cataract prevalence.
UNASSIGNED: Our analysis identified significant inverse associations between the intake of vitamins E, B6, and niacin and the risk of cataract development. Specifically, higher intakes of vitamin B6 (OR = 0.85, 95% CI = 0.76-0.96, p = 0.0073) and niacin (OR = 0.98, 95% CI = 0.97-1.00, p = 0.0067) in the top quartile were significantly associated with a reduced likelihood of cataract occurrence. Vitamin E intake showed a consistent reduction in cataract risk across different intake levels (OR = 0.96, 95% CI = 0.94-0.99, p = 0.0087), demonstrating a nonlinear inverse correlation.
UNASSIGNED: The outcomes indicate that elevated consumption of vitamin B6 and niacin, in conjunction with regular vitamin E intake, may have the potential to delay or prevent cataract genesis. These results suggest a novel nutritional strategy for cataract prevention and management, advocating that focused nutrient supplementation could be instrumental in preserving eye health and reducing the risk of cataracts. Further research is recommended to validate these findings and establish optimal dosages for maximum benefit.