UNASSIGNED:使用增强深度成像谱域光学断层扫描(EDISD-OCT)测量高度近视眼的脉络膜厚度(CT),并探讨CT与眼轴长度(AL)和角膜曲率之间的关系。
UNASSIGNED:本研究评估了在眼科接受治疗的33例双眼高度近视(等效球度≥-6D或AL≥26mm)患者的66只眼,河北医科大学第四医院2020年8月至2021年8月(高度近视组)。对照组包括27名健康志愿者的54只眼。两组患者年龄均为18~40岁。采用EDISD-OCT测量中心凹下脉络膜厚度(SFCT)的CT和从中心凹到鼻及颞侧的CT,间隔500~2500μm。眼内压,屈光度,眼轴,角膜曲率,比较两组患者的CT和CT。CT之间的相关性,屈光度和AL由Pearson'sr.
UASSIGNED:屈光度,AL,垂直角膜曲率,高度近视组的CT和CT明显高于对照组(P<0.05)。两组SFCT与AL均存在显著相关性(P<0.05)。高度近视组AL与CT呈负相关(r=-0.395,P<0.05),对照组AL与CT呈正相关(r=0.29,P<0.05)。AL和性别之间存在弱相关性,眼内压,和水平角膜曲率(P<0.05),AL与屈光度呈负相关(r=-0.861,P<0.001)。
UNASSIGNED:EDISD-OCT可以定量测量高度近视的CT。高度近视患者的CT明显薄于同龄对照组。屈光度之间有显著的相关性,AL和CT,表明AL是指示近视程度的参数,CT改变可能在高度近视的发生发展中起作用。
UNASSIGNED: To measure choroidal thickness (CT) in highly myopia eyes using enhanced depth imaging spectral-domain optical tomography (EDI SD-OCT) and explore the relationship between the CT and axial length (AL) and corneal curvature.
UNASSIGNED: This study assessed 66 eyes of 33 patients with both eyes of high myopia (equivalent sphericity ≥-6D or AL≥26mm) who underwent treatment at the department of ophthalmology, fourth hospital of Hebei Medical University from August 2020 to August 2021(High-myopia group). The control group included 54 eyes from 27 healthy volunteers. The patients in the two groups were 18~40 years old. EDI SD-OCT was used to measure the CT of subfoveal choroidal thickness (SFCT) and CT from fovea to nasal and temporal sides at an interval of 500~2500μm. The intraocular pressure, diopter, ocular axis, corneal curvature, and CT were compared between the two groups. The correlation between CT, diopter and AL was measured by Pearson\'s r.
UNASSIGNED: The diopter, AL, vertical corneal curvature, and CT in the high-myopia group were significantly higher than those in the control group (P<0.05). There was significant correlation between SFCT and AL in both groups (P<0.05). There was a negative correlation between AL and CT in high-myopia group (r=-0.395, P<0.05), and a positive correlation between AL and CT in control group (r=0.29, P<0.05). There was a weak correlation between AL and gender, intraocular pressure, and horizontal corneal curvature(P<0.05), and a negative correlation between AL and diopter (r=-0.861, P<0.001).
UNASSIGNED: EDI SD-OCT can quantitatively measure the CT of high myopia. The CT of patients with high myopia was significantly thinner than that of the control group of the same age. There was a significant correlation between diopter, AL and CT, suggesting that AL is a parameter indicating the degree of myopia, and the change of CT may play a role in the occurrence and development of high myopia.