目的:本研究的目的是确定牙齿组织与镰状细胞性贫血(SCA)之间的关系,以及它如何影响与口腔健康相关的生活质量。
方法:这是一项队列研究,在Yolo中心的SCA牙科服务中,对154名有或没有SCA的刚果参与者进行了研究,金沙萨,年龄至少6岁,没有临床严重疾病史(住院和输血),他们经常被监控。纳入标准是在纳入本研究之前至少6个月内,在卫生服务机构中进行SCA的诊断确认。使用牙科镜和探针通过临床检查评估牙科组织。使用牙齿缺失指数(DMFT)评估参与者的牙齿状态。对于口腔健康相关的生活质量(OHrQoL),刚果版本的感知问卷,根据口腔健康影响概况(OHIP-23)修改,用于参与者。每个问题都必须用是或否回答,取决于参与者对口腔健康相关生活质量是否满意(结局=1)或不满意(结局=0).
结果:在154名参与者中,年龄从6岁到64岁,平均年龄为19.5±7(SD)岁,96例出现SCA,只有68例正确随访;102例没有出现SCA,只有86例正确随访。SCA组的DMFT和dmft指数较高,分别为2.9和2.5。对于龋齿,SCA组与对照组之间的差异是显着的,缺失的牙齿,牙齿填充,没有龋齿。SCA组和对照组生活质量的不同维度比较,23个项目中有15个有统计学意义。
结论:本研究强烈证实了龋齿和牙齿缺失与镰状细胞性贫血之间的关联。其次,SCA参与者的生活质量似乎很差,与对照组相比。
OBJECTIVE: The aim of this study was to determine the association between dental tissues and sickle cell anemia (SCA) and how it impacts the quality of life related to oral health.
METHODS: It was a cohort study of 154 Congolese participants with and without SCA conducted in the dental service of SCA at the Yolo Center, Kinshasa, aged at least 6 years and without a history of clinically severe conditions (hospitalization and blood transfusion), who were regularly monitored. The inclusion criteria were the diagnosis confirmation of SCA at the health service in a period of at least 6 months before enrollment in this study. Dental tissues were assessed by a clinical examination using a dental mirror and probe. The index of Decayed-Missing-Filled Teeth (DMFT) was used to assess the dental state of the participants. For Oral Health-related Quality of Life (OHrQoL), the Congolese versions of the perception questionnaires, modified from the Oral Health Impacts Profile (OHIP-23), were used for participants. Each question had to be answered by yes or no, depending on whether the participant was satisfied (outcome = 1) or dissatisfied (outcome = 0) about an oral health-related quality of life.
RESULTS: Of the 154 participants, aged from 6 to 64 years, with a mean age of 19.5 ± 7 (SD) years, 96 presented with SCA and only 68 were correctly followed; 102 did not present SCA and only 86 were correctly followed. The DMFT and dmft indexes were higher in the SCA group, being 2.9 and 2.5, respectively. The difference between the SCA group and the control group was significant for decayed teeth, missing teeth, filled teeth and no caries. Of the different dimensions of quality of life that were compared between the SCA group and control group, 15 of 23 items were statistically significant.
CONCLUSIONS: The present study strongly confirmed an association between dental caries and missing teeth with sickle cell anemia. Secondly, the quality of life for SCA participants seems to be poor, compared to the control group.