目的:本研究探讨精准护理联合间歇性充气加压(IPC)装置预防卵巢癌患者围手术期深静脉血栓(DVT)的效果。
方法:回顾性分析2019年2月至2023年4月西安市人民医院卵巢癌手术患者136例。将患者分为两组:71例患者接受IPC干预的精准护理(研究组),其余患者接受标准护理(对照组)。分析的关键变量包括手术持续时间,术中失血,术后输血需求,肢体周长的变化,和凝血参数的变化激活部分凝血活酶时间(APTT),D-二聚体(D-D),纤维蛋白原(FIB),术前、术后凝血酶原时间(PT)。记录两组DVT的发生率,以确定深静脉血栓形成的危险因素。
结果:两组间在手术时间上无显著差异,术中失血,术后输血率(P>0.05)。干预后,研究组有显著改善,与对照组相比,FIB和D-D水平降低,PT和APTT水平升高(P<0.05)。此外,研究组干预后的肢体周长差异明显较小,DVT发生率较低(P=0.003).精准护理结合IPC,干预前D-D<498.5,FIGOIII+IV期被确定为DVT发生的独立因素.
结论:与常规护理相比,精准护理与IPC装置配合可显著降低卵巢癌患者围手术期DVT的风险。
OBJECTIVE: This study investigated the efficacy of precision nursing combined with intermittent pneumatic compression (IPC) devices in preventing perioperative deep vein thrombosis (DVT) in patients with ovarian cancer.
METHODS: A retrospective analysis was conducted on 136 ovarian cancer surgery patients at Xi\'an People\'s Hospital from February 2019 to April 2023. The patients were divided into two groups: 71 patients received precision nursing with IPC intervention (study group), while the remaining received standard nursing care (control group). Key variables analyzed included operation duration, intraoperative blood loss, postoperative blood transfusion requirements, changes in limb circumference, and variations in coagulation parameters activated partial thromboplastin time (APTT), D-Dimer (D-D), Fibrinogen (FIB), and Prothrombin Time (PT) before and after surgery. The incidence of DVT was recorded in both groups to determine risk factors for deep vein thrombosis.
RESULTS: No significant differences were observed between the groups regarding operation duration, intraoperative blood loss, and postoperative blood transfusion rates (P > 0.05). Post-intervention, significant improvements were noted in the study group, with reduced FIB and D-D levels and increased PT and APTT levels compared to the control group (P < 0.05). Furthermore, the study group exhibited a significantly smaller post-intervention difference in limb circumference and a lower incidence of DVT (P=0.003). Precision nursing combined with IPC, pre-intervention D-D < 498.5, and FIGO stages III+IV were identified as independent factors against DVT development.
CONCLUSIONS: Precision nursing paired with an IPC device significantly reduces the risk of perioperative DVT in ovarian cancer patients compared to conventional care.